CN103124560B - 制备积雪草提取物的方法 - Google Patents

制备积雪草提取物的方法 Download PDF

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Publication number
CN103124560B
CN103124560B CN201180043552.5A CN201180043552A CN103124560B CN 103124560 B CN103124560 B CN 103124560B CN 201180043552 A CN201180043552 A CN 201180043552A CN 103124560 B CN103124560 B CN 103124560B
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mixture
extract
temperature
weight
solvent
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Expired - Fee Related
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CN103124560A (zh
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C·杜瓦尔
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Naturex Inc
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Naturex Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Steroid Compounds (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201180043552.5A 2010-09-09 2011-09-02 制备积雪草提取物的方法 Expired - Fee Related CN103124560B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1057179A FR2964570A1 (fr) 2010-09-09 2010-09-09 Procede de preparation d'un extrait de centella asiatica
FR1057179 2010-09-09
PCT/FR2011/052013 WO2012032250A1 (fr) 2010-09-09 2011-09-02 Procédé de préparation d'un extrait de centella asiatica

Publications (2)

Publication Number Publication Date
CN103124560A CN103124560A (zh) 2013-05-29
CN103124560B true CN103124560B (zh) 2015-09-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180043552.5A Expired - Fee Related CN103124560B (zh) 2010-09-09 2011-09-02 制备积雪草提取物的方法

Country Status (8)

Country Link
US (1) US9487552B2 (enExample)
EP (1) EP2613792B1 (enExample)
JP (1) JP5778772B2 (enExample)
KR (1) KR20130103745A (enExample)
CN (1) CN103124560B (enExample)
BR (1) BR112013005706A2 (enExample)
FR (1) FR2964570A1 (enExample)
WO (1) WO2012032250A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3023482B1 (fr) * 2014-07-11 2016-07-15 Laboratoires Lea Extrait hydroglycerine d'ombellifere pour un usage cosmetique
KR101582465B1 (ko) 2014-08-26 2016-01-05 김효상 조립식 휴대폰 거치장치
HRP20230726T1 (hr) * 2016-07-17 2023-10-13 Oneness Biotech Co., Ltd. Topikalna formulacija za poticanje zarastanja rana
CN106860494A (zh) * 2017-02-28 2017-06-20 宁波绿之健药业有限公司 一种积雪草提取物的制备工艺
CN109879926B (zh) * 2019-02-27 2021-07-23 江西省药品检验检测研究院 连钱草中的三萜苷类化合物及其提取分离方法
KR102211883B1 (ko) 2020-01-31 2021-02-02 손현용 스마트폰용 무 전원 확성기
CN111285916B (zh) * 2020-02-14 2021-07-02 浏阳朗林生物科技有限公司 一种积雪草总苷含量高的积雪草提取物的制备方法
CN113801184B (zh) * 2020-06-16 2025-03-25 盈科瑞（天津）创新医药研究有限公司 一种羟基积雪草苷的纯化方法
CN112773745A (zh) * 2021-02-06 2021-05-11 广州贝塔健康生物科技有限公司 一种积雪草苷提取物制备方法及在化妆品中的应用
CN115813964A (zh) * 2022-11-09 2023-03-21 广州好肌肤科技有限公司 一种具有抗氧化的积雪草提取物的提取工艺及应用
KR102786604B1 (ko) * 2022-12-12 2025-03-26 주식회사 코스모바이오 병풀로부터 아시아티코사이드 및 마데카소사이드의 분리 정제 방법
CN119431486A (zh) * 2024-11-01 2025-02-14 南宁兴景科技有限公司 一种积雪草利用膜分离法获得高含量羟基积雪草苷的方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1774257A (zh) * 2002-12-10 2006-05-17 拜尔消费者保健股份公司 制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法
CN101007037A (zh) * 2007-01-23 2007-08-01 上海海一生物科技有限公司 美洲一枝黄花总三萜提取物及其制备方法和用途
CN101323637A (zh) * 2008-07-29 2008-12-17 卢照凯 一种积雪草甙及其制备方法
CN101375933A (zh) * 2007-08-29 2009-03-04 财团法人生物技术开发中心 制备用于治疗皮肤病症和促进伤口愈合的植物提取物的方法
CN101652143A (zh) * 2007-02-12 2010-02-17 Indus生物技术私人有限公司 用于选择性5-羟色胺再摄取抑制的组合物及其方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100228873B1 (ko) * 1997-03-24 1999-11-01 강재헌 센텔라아시아티카에서 분리한 아시아티코사이드와 마테카소 사이드의 수용성 추출물을 함유한 간세포 및 항간섬유화 치료제
CN1325062C (zh) * 2005-12-06 2007-07-11 新疆特丰药业股份有限公司 从孕马尿中获取结合雌激素混合物方法及其所用大孔吸附树脂的应用
EP1867729A1 (en) * 2006-06-14 2007-12-19 Libragen Water soluble phenolics derivatives with dermocosmetic and therapeutic applications
FR2915899B1 (fr) * 2007-05-07 2012-09-21 Burgundy Nouvelles utilisations de l'hibiscus, notamment pharmaceutiques.
CN101549075B (zh) * 2009-05-08 2011-08-03 上海现代制药股份有限公司 一种治疗乳腺增生的中药组合物及其制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1774257A (zh) * 2002-12-10 2006-05-17 拜尔消费者保健股份公司 制备富含羟基积雪草苷和特米诺苷的积雪草酸提取物的方法
CN101007037A (zh) * 2007-01-23 2007-08-01 上海海一生物科技有限公司 美洲一枝黄花总三萜提取物及其制备方法和用途
CN101652143A (zh) * 2007-02-12 2010-02-17 Indus生物技术私人有限公司 用于选择性5-羟色胺再摄取抑制的组合物及其方法
CN101375933A (zh) * 2007-08-29 2009-03-04 财团法人生物技术开发中心 制备用于治疗皮肤病症和促进伤口愈合的植物提取物的方法
CN101323637A (zh) * 2008-07-29 2008-12-17 卢照凯 一种积雪草甙及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中药现代化种植、加工和质控技术研究进展;孟冬霞等;《中兽医医药杂志》;20071231(第05期);第68-70页 *
积雪草提取纯化工艺的研究;卢茂芳等;《湖南中医药大学学报》;20071231;第27卷(第01期);第16-19页 *

Also Published As

Publication number Publication date
US9487552B2 (en) 2016-11-08
WO2012032250A1 (fr) 2012-03-15
EP2613792B1 (fr) 2016-09-21
HK1185010A1 (en) 2014-02-07
EP2613792A1 (fr) 2013-07-17
CN103124560A (zh) 2013-05-29
JP2013537888A (ja) 2013-10-07
JP5778772B2 (ja) 2015-09-16
KR20130103745A (ko) 2013-09-24
BR112013005706A2 (pt) 2016-05-10
FR2964570A1 (fr) 2012-03-16
US20130172541A1 (en) 2013-07-04

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