BR112013005706A2 - métodos para preparar um extrato refinado e um extrato purificado de centella asiatica - Google Patents

métodos para preparar um extrato refinado e um extrato purificado de centella asiatica

Info

Publication number
BR112013005706A2
BR112013005706A2 BR112013005706A BR112013005706A BR112013005706A2 BR 112013005706 A2 BR112013005706 A2 BR 112013005706A2 BR 112013005706 A BR112013005706 A BR 112013005706A BR 112013005706 A BR112013005706 A BR 112013005706A BR 112013005706 A2 BR112013005706 A2 BR 112013005706A2
Authority
BR
Brazil
Prior art keywords
extract
centella asiatica
methods
preparing
purified
Prior art date
Application number
BR112013005706A
Other languages
English (en)
Inventor
Charles Duval
Original Assignee
Naturex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Naturex filed Critical Naturex
Publication of BR112013005706A2 publication Critical patent/BR112013005706A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

métodos para preparar um extrato refinado e um extrato purificado de centella asiatica. a invenção diz respeito a um método para preparar um extrato refinado de centella asiatica compreendendo uma mistura de madecassoside e terminoloside. o método compreende: passagem sobre resina adsorvente, eluição com um eluente compreendendo pelo menos 30% em peso de um solvente alcoólico, e uma etapa de recristalização usando uma mistura de solventes, compreendendo água e um solvente alcoólico.
BR112013005706A 2010-09-09 2011-09-02 métodos para preparar um extrato refinado e um extrato purificado de centella asiatica BR112013005706A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1057179A FR2964570A1 (fr) 2010-09-09 2010-09-09 Procede de preparation d'un extrait de centella asiatica
PCT/FR2011/052013 WO2012032250A1 (fr) 2010-09-09 2011-09-02 Procédé de préparation d'un extrait de centella asiatica

Publications (1)

Publication Number Publication Date
BR112013005706A2 true BR112013005706A2 (pt) 2016-05-10

Family

ID=43728752

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013005706A BR112013005706A2 (pt) 2010-09-09 2011-09-02 métodos para preparar um extrato refinado e um extrato purificado de centella asiatica

Country Status (9)

Country Link
US (1) US9487552B2 (pt)
EP (1) EP2613792B1 (pt)
JP (1) JP5778772B2 (pt)
KR (1) KR20130103745A (pt)
CN (1) CN103124560B (pt)
BR (1) BR112013005706A2 (pt)
FR (1) FR2964570A1 (pt)
HK (1) HK1185010A1 (pt)
WO (1) WO2012032250A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3023482B1 (fr) * 2014-07-11 2016-07-15 Laboratoires Lea Extrait hydroglycerine d'ombellifere pour un usage cosmetique
KR101582465B1 (ko) 2014-08-26 2016-01-05 김효상 조립식 휴대폰 거치장치
DK3484457T3 (da) * 2016-07-17 2023-07-10 Oneness Biotech Co Ltd Topisk formulering til fremme af sårheling
CN106860494A (zh) * 2017-02-28 2017-06-20 宁波绿之健药业有限公司 一种积雪草提取物的制备工艺
CN109879926B (zh) * 2019-02-27 2021-07-23 江西省药品检验检测研究院 连钱草中的三萜苷类化合物及其提取分离方法
KR102211883B1 (ko) 2020-01-31 2021-02-02 손현용 스마트폰용 무 전원 확성기
CN111285916B (zh) * 2020-02-14 2021-07-02 浏阳朗林生物科技有限公司 一种积雪草总苷含量高的积雪草提取物的制备方法
CN112773745A (zh) * 2021-02-06 2021-05-11 广州贝塔健康生物科技有限公司 一种积雪草苷提取物制备方法及在化妆品中的应用
CN115813964A (zh) * 2022-11-09 2023-03-21 广州好肌肤科技有限公司 一种具有抗氧化的积雪草提取物的提取工艺及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100228873B1 (ko) * 1997-03-24 1999-11-01 강재헌 센텔라아시아티카에서 분리한 아시아티코사이드와 마테카소 사이드의 수용성 추출물을 함유한 간세포 및 항간섬유화 치료제
FR2848117B1 (fr) * 2002-12-10 2006-08-04 Roche Consumer Health Ltd Procede de preparation d'un extrait de centella asiatica riche en madecassoside et en terminoloside
CN1325062C (zh) * 2005-12-06 2007-07-11 新疆特丰药业股份有限公司 从孕马尿中获取结合雌激素混合物方法及其所用大孔吸附树脂的应用
EP1867729A1 (en) * 2006-06-14 2007-12-19 Libragen Water soluble phenolics derivatives with dermocosmetic and therapeutic applications
CN101007037A (zh) * 2007-01-23 2007-08-01 上海海一生物科技有限公司 美洲一枝黄花总三萜提取物及其制备方法和用途
ATE495749T1 (de) * 2007-02-12 2011-02-15 Indus Biotech Private Ltd Zusammensetzung für selektive hemmung der serotoninwiederaufnahme und verfahren dafür
FR2915899B1 (fr) * 2007-05-07 2012-09-21 Burgundy Nouvelles utilisations de l'hibiscus, notamment pharmaceutiques.
US8449924B2 (en) * 2007-08-29 2013-05-28 Development Center For Biotechnology Process for the preparation of plant extracts for treating skin disorders and enhancing healing of wounds
CN101323637B (zh) * 2008-07-29 2010-12-22 卢照凯 一种积雪草甙及其制备方法
CN101549075B (zh) * 2009-05-08 2011-08-03 上海现代制药股份有限公司 一种治疗乳腺增生的中药组合物及其制备方法

Also Published As

Publication number Publication date
US9487552B2 (en) 2016-11-08
WO2012032250A1 (fr) 2012-03-15
EP2613792B1 (fr) 2016-09-21
JP2013537888A (ja) 2013-10-07
US20130172541A1 (en) 2013-07-04
CN103124560B (zh) 2015-09-23
FR2964570A1 (fr) 2012-03-16
EP2613792A1 (fr) 2013-07-17
KR20130103745A (ko) 2013-09-24
HK1185010A1 (en) 2014-02-07
CN103124560A (zh) 2013-05-29
JP5778772B2 (ja) 2015-09-16

Similar Documents

Publication Publication Date Title
BR112013005706A2 (pt) métodos para preparar um extrato refinado e um extrato purificado de centella asiatica
ECSP11011387A (es) Anticuerpos biespecíficos anti-erbb-3/anti-c-met
BR112012007873A2 (pt) "sistema e método para amortecer vibrações em uma turbina eólica".
ECSP10010439A (es) Antagonistas n,n-disustituidos de aminoalquilbifenilo de receptores d2 de prostaglandina
EA201491161A1 (ru) Фторированные модуляторы рецепторов эстрогенов и их применение
CO6680708A2 (es) Compuesto modulares de estrógenos y composiciones que comprenden los mismos
CR20140431A (es) Anticuerpos biespecificos contra tweak humana e il 17 humana y usos de los mismos
CO6480918A2 (es) Antagonistas policíclicos de receptores de ácido lisofosfatídico.
EA201590590A1 (ru) Модуляторы рецептора андрогенов и их применение
CL2008000825A1 (es) Compuestos heterociclicos derivados de quinolincarboxamidas utiles como antagonistas de p2x7; su metodo de preparacion; la composicion farmaceutica que lo contiene; el emtodo de preparacion de la composicion; y el uso de los mismos para preparar medicamentos utiles en artritis reumatoide.
CO6450612A2 (es) Compuestos 1-cianoetilheterociclilcarboxamida sustituidos 750
BR112015022566A2 (pt) composto e composição farmacêutica
BR112014010528A2 (pt) composição de resina de expóxi curável, e, métodos para curar um sistema de resina de expóxi e para fabricar uma estrutura de compósito
CL2008002076A1 (es) Compuestos derivados de ariloxazoles sustituidos; procedimiento de preparacion de dichos compuestos; composicion farmaceutica que los comprende; y su uso para tratar diabetes, sindrome metabolico, dislipidemias, entre otras enfermedades.
CL2013001101A1 (es) Compuestos derivados de rasagilina enriquecida con deuterio; su proceso de preparacion; mezcla de al menos dos compuestos enriquecidos con deuterio; composicion farmaceutica que los comprende, util para tratar un trastorno neurodegenerativo tal como mal de parkinson, sindrome de piernas inquietas, perdida auditiva y disfuncion olfativa.
ECSP12011701A (es) Anticuerpos anti-cdcp1 humanizados
BR112015017606A2 (pt) composição, método de produzir a composição, utilização da composição e combustível obtido a partir da composição
CL2012003681A1 (es) Compuestos derivados de piperidina; composicion farmaceutica; y su uso como inhibidores de acetil-coa carboxilasa para el tratamiento de trastornos metabolicos, tales como obesidad y diabetes.
EA201391489A1 (ru) Композиции со сниженной вязкостью
BR112012020628A2 (pt) fotoiniciador de éter polialquílico, uso de um fotoiniciador de éter polialquílico, método para curar uma composição de matriz, e, composição de matriz
UY31622A1 (es) Antagonistas de aminoalquilbifenilo n,n-disubstituidos de receptores de prostaglandina d2
EA201290790A1 (ru) Биоадгезивные композиции местных анестетиков
BR112015023209A8 (pt) novos medicamentos compreendendo uma composição de anticorpo enriquecida com uma carga principal de isoforma
BRPI0922813B8 (pt) composição termofixa para partes e revestimentos compósitos intumescentes
BRPI1015324A2 (pt) sistema curável, método para a fabricação de um produto curado, produto curado, e, usos do produto curado e do sistema curável

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2477 DE 26-06-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.