CN103087133B - 嘌呤衍生物作为腺苷a1受体激动剂及其用法 - Google Patents
嘌呤衍生物作为腺苷a1受体激动剂及其用法 Download PDFInfo
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- CN103087133B CN103087133B CN201210444152.1A CN201210444152A CN103087133B CN 103087133 B CN103087133 B CN 103087133B CN 201210444152 A CN201210444152 A CN 201210444152A CN 103087133 B CN103087133 B CN 103087133B
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| CN200580024844.9A CN101010085B (zh) | 2004-05-26 | 2005-05-25 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
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| CN200580024844.9A Division CN101010085B (zh) | 2004-05-26 | 2005-05-25 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
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| CN103087133A CN103087133A (zh) | 2013-05-08 |
| CN103087133B true CN103087133B (zh) | 2016-09-14 |
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Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103087133B (zh) * | 2004-05-26 | 2016-09-14 | 伊诺泰克制药公司 | 嘌呤衍生物作为腺苷a1受体激动剂及其用法 |
| CN101437526A (zh) * | 2004-09-20 | 2009-05-20 | 伊诺泰克制药公司 | 嘌呤衍生物及其用法 |
| EA015683B1 (ru) * | 2005-11-30 | 2011-10-31 | Инотек Фармасьютикалз Корпорейшн | Производные пурина и способы их применения |
| BRPI0709124A2 (pt) * | 2006-03-23 | 2011-06-28 | Inotek Pharmaceuticals Corp | composto purina e métodos de uso dos mesmos |
| JP5128578B2 (ja) * | 2006-04-04 | 2013-01-23 | エモディス ゲーエムベーハー | 解離性障害の治療のためのκ−オピオイド受容体アンタゴニスト含有組成物の利用 |
| NZ596428A (en) | 2009-05-01 | 2014-03-28 | Inotek Pharmaceuticals Corp | Method of reducing intraocular pressure in humans |
| EA201270102A1 (ru) | 2009-06-30 | 2012-08-30 | Форест Лэборетериз Холдингз Лимитед | Соединения алкокси-карбонил-амино-алкинил-аденозина и их производные в качестве агонистов ar |
| WO2011053569A1 (en) * | 2009-10-26 | 2011-05-05 | Inotek Pharmaceuticals Corporation | Ophthalmic formulation and method of manufacture thereof |
| LT2523669T (lt) * | 2010-01-11 | 2017-04-25 | Inotek Pharmaceuticals Corporation | Akispūdžio mažinimo būdas, derinys ir rinkinys |
| US8455457B2 (en) * | 2010-03-19 | 2013-06-04 | Inotek Pharmaceuticals Corporation | Combination compositions for reducing intraocular pressure |
| JP2013522322A (ja) * | 2010-03-19 | 2013-06-13 | イノテック ファーマシューティカルズ コーポレイション | 眼内圧を下げるためのアデノシンａ１受容体アゴニストと炭酸脱水酵素阻害剤との組合せ組成物 |
| PH12012501906A1 (en) | 2010-03-26 | 2013-01-14 | Inotek Pharmaceuticals Corp | Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof |
| KR20130029049A (ko) | 2010-03-26 | 2013-03-21 | 이노텍 파마슈티컬스 코포레이션 | 아데노신 화합물 및 이의 용도 |
| PT2807178T (pt) | 2012-01-26 | 2017-08-08 | Inotek Pharmaceuticals Corp | Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação |
| NZ630759A (en) | 2013-03-15 | 2017-07-28 | Inotek Pharmaceuticals Corp | Ophthalmic formulations comprising an a1 agonist |
| GB2582361A (en) * | 2019-03-21 | 2020-09-23 | Univ Warwick | Adenosine receptor agonists |
| JP2022538408A (ja) * | 2019-06-21 | 2022-09-02 | アカデミー オブ ミリタリー メディカル サイエンシズ | Ａ２ａアデノシン受容体アゴニスト活性を有する６－ヒドラジノアデノシン化合物 |
| DE102021120112A1 (de) | 2021-08-03 | 2023-02-09 | Bayerische Motoren Werke Aktiengesellschaft | Schnittwerkzeug für ein Metallblech und ein Verfahren zum Betreiben eines Schnittwerkzeugs für ein Metallblech |
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| US3819613A (en) * | 1970-12-28 | 1974-06-25 | Takeda Chemical Industries Ltd | Adenosine derivatives and the production thereof |
| US3832341A (en) * | 1971-09-10 | 1974-08-27 | Hoffmann La Roche | Purine nucleoside nitrates |
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