KR101167342B1 - 아데노신 ａ1 수용체 아고니스트로서의 퓨린 유도체 및 이것의 사용 방법 - Google Patents

아데노신 ａ1 수용체 아고니스트로서의 퓨린 유도체 및 이것의 사용 방법 Download PDF

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KR101167342B1
KR101167342B1 KR1020067027319A KR20067027319A KR101167342B1 KR 101167342 B1 KR101167342 B1 KR 101167342B1 KR 1020067027319 A KR1020067027319 A KR 1020067027319A KR 20067027319 A KR20067027319 A KR 20067027319A KR 101167342 B1 KR101167342 B1 KR 101167342B1
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purine derivative
purine
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derivative
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KR20070028456A (ko
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프라카쉬 자그타프
크샤바 스자보
앤드류 엘. 살쯔만
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이노텍 파마슈티컬스 코포레이션
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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KR1020067027319A 2004-05-26 2005-05-25 아데노신 ａ1 수용체 아고니스트로서의 퓨린 유도체 및 이것의 사용 방법 Expired - Fee Related KR101167342B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US57480504P 2004-05-26 2004-05-26
US60/574,805 2004-05-26
US58826304P 2004-07-15 2004-07-15
US60/588,263 2004-07-15
PCT/US2005/018381 WO2005117910A2 (en) 2004-05-26 2005-05-25 Purine derivatives as adenosine a1 receptor agonists and methods of use thereof

Related Child Applications (1)

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KR1020117027975A Division KR101267202B1 (ko) 2004-05-26 2005-05-25 아데노신 ａ1 수용체 아고니스트로서의 퓨린 유도체 및 이것의 사용 방법

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KR20070028456A KR20070028456A (ko) 2007-03-12
KR101167342B1 true KR101167342B1 (ko) 2012-07-19

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KR1020067027319A Expired - Fee Related KR101167342B1 (ko) 2004-05-26 2005-05-25 아데노신 ａ1 수용체 아고니스트로서의 퓨린 유도체 및 이것의 사용 방법
KR1020117027975A Expired - Fee Related KR101267202B1 (ko) 2004-05-26 2005-05-25 아데노신 ａ1 수용체 아고니스트로서의 퓨린 유도체 및 이것의 사용 방법

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US (3) US7423144B2 (https=)
EP (2) EP2221307A1 (https=)
JP (3) JP4484928B2 (https=)
KR (2) KR101167342B1 (https=)
CN (1) CN103087133B (https=)
AT (1) ATE462704T1 (https=)
AU (1) AU2005249430B2 (https=)
BR (1) BRPI0510406A (https=)
CA (1) CA2567289C (https=)
CY (1) CY1110159T1 (https=)
DE (1) DE602005020286D1 (https=)
DK (1) DK1758596T3 (https=)
EA (1) EA011826B1 (https=)
ES (1) ES2343421T3 (https=)
HR (1) HRP20100344T2 (https=)
IL (1) IL179400A (https=)
ME (1) ME01072B (https=)
MX (1) MXPA06013560A (https=)
NO (1) NO339450B1 (https=)
NZ (1) NZ551951A (https=)
PL (1) PL1758596T3 (https=)
PT (1) PT1758596E (https=)
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CN101437526A (zh) * 2004-09-20 2009-05-20 伊诺泰克制药公司 嘌呤衍生物及其用法
EA015683B1 (ru) * 2005-11-30 2011-10-31 Инотек Фармасьютикалз Корпорейшн Производные пурина и способы их применения
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JP5128578B2 (ja) * 2006-04-04 2013-01-23 エモディス ゲーエムベーハー 解離性障害の治療のためのκ−オピオイド受容体アンタゴニスト含有組成物の利用
NZ596428A (en) 2009-05-01 2014-03-28 Inotek Pharmaceuticals Corp Method of reducing intraocular pressure in humans
EA201270102A1 (ru) 2009-06-30 2012-08-30 Форест Лэборетериз Холдингз Лимитед Соединения алкокси-карбонил-амино-алкинил-аденозина и их производные в качестве агонистов ar
WO2011053569A1 (en) * 2009-10-26 2011-05-05 Inotek Pharmaceuticals Corporation Ophthalmic formulation and method of manufacture thereof
LT2523669T (lt) * 2010-01-11 2017-04-25 Inotek Pharmaceuticals Corporation Akispūdžio mažinimo būdas, derinys ir rinkinys
US8455457B2 (en) * 2010-03-19 2013-06-04 Inotek Pharmaceuticals Corporation Combination compositions for reducing intraocular pressure
JP2013522322A (ja) * 2010-03-19 2013-06-13 イノテック ファーマシューティカルズ コーポレイション 眼内圧を下げるためのアデノシンａ１受容体アゴニストと炭酸脱水酵素阻害剤との組合せ組成物
PH12012501906A1 (en) 2010-03-26 2013-01-14 Inotek Pharmaceuticals Corp Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof
KR20130029049A (ko) 2010-03-26 2013-03-21 이노텍 파마슈티컬스 코포레이션 아데노신 화합물 및 이의 용도
PT2807178T (pt) 2012-01-26 2017-08-08 Inotek Pharmaceuticals Corp Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação
NZ630759A (en) 2013-03-15 2017-07-28 Inotek Pharmaceuticals Corp Ophthalmic formulations comprising an a1 agonist
GB2582361A (en) * 2019-03-21 2020-09-23 Univ Warwick Adenosine receptor agonists
JP2022538408A (ja) * 2019-06-21 2022-09-02 アカデミー オブ ミリタリー メディカル サイエンシズ Ａ２ａアデノシン受容体アゴニスト活性を有する６－ヒドラジノアデノシン化合物
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