CN102574785A - 四取代的杂芳基化合物和它们作为mdm2和/或mdm4调节剂的用途 - Google Patents

四取代的杂芳基化合物和它们作为mdm2和/或mdm4调节剂的用途 Download PDF

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CN102574785A
CN102574785A CN2010800482502A CN201080048250A CN102574785A CN 102574785 A CN102574785 A CN 102574785A CN 2010800482502 A CN2010800482502 A CN 2010800482502A CN 201080048250 A CN201080048250 A CN 201080048250A CN 102574785 A CN102574785 A CN 102574785A
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alkyl
amino
carbonyl
phenyl
chloro
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G·博尔德
P·菲雷
F·热西耶
J·卡伦
J·赫尔戈维奇李斯特万
K·马苏亚
A·沃佩尔
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Novartis AG
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CN2010800482502A 2009-08-26 2010-08-24 四取代的杂芳基化合物和它们作为mdm2和/或mdm4调节剂的用途 Pending CN102574785A (zh)

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US23710709P 2009-08-26 2009-08-26
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PCT/EP2010/062300 WO2011023677A1 (en) 2009-08-26 2010-08-24 Tetra-substituted heteroaryl compounds and their use as mdm2 and/or mdm4 modulators

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WO2011046771A1 (en) 2009-10-14 2011-04-21 Schering Corporation SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
JO2998B1 (ar) 2010-06-04 2016-09-05 Amgen Inc مشتقات بيبيريدينون كمثبطات mdm2 لعلاج السرطان
SI2603600T1 (sl) 2010-08-13 2019-04-30 Aileron Therapeutics, Inc. Peptidomimetični makrocikli
WO2013049250A1 (en) 2011-09-27 2013-04-04 Amgen Inc. Heterocyclic compounds as mdm2 inhibitors for the treatment of cancer
WO2013059525A1 (en) 2011-10-18 2013-04-25 Aileron Therapeutics, Inc. Peptidomimetic macrocyles
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