CN102295606A - 合成3-（1，3-苯并间二氧杂环戊烯-5-基）-6-（4-环丙基哌嗪-1-基）-哒嗪的方法及其适用的中间体 - Google Patents
合成3-（1，3-苯并间二氧杂环戊烯-5-基）-6-（4-环丙基哌嗪-1-基）-哒嗪的方法及其适用的中间体 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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| EP06120117 | 2006-09-05 | ||
| EP06120117.4 | 2006-09-05 |
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| CNA2007800197395A Division CN101460487A (zh) | 2006-05-29 | 2007-05-22 | 3-(1，3-苯并间二氧杂环戊烯- 5-基)-6-(4-环丙基哌嗪-1-基)-哒嗪、其盐和溶剂合物及其作为组胺h3受体拮抗剂的用途 |
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| CNA2007800197395A Pending CN101460487A (zh) | 2006-05-29 | 2007-05-22 | 3-(1，3-苯并间二氧杂环戊烯- 5-基)-6-(4-环丙基哌嗪-1-基)-哒嗪、其盐和溶剂合物及其作为组胺h3受体拮抗剂的用途 |
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| JP2008536950A (ja) | 2005-04-18 | 2008-09-11 | ニューロジェン・コーポレーション | 置換ヘテロアリールのｃｂ１拮抗薬 |
| FR2885615B1 (fr) | 2005-05-12 | 2007-06-22 | Servier Lab | Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2885616B1 (fr) | 2005-05-12 | 2007-06-22 | Servier Lab | Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| KR101286569B1 (ko) | 2005-07-04 | 2013-07-23 | 하이 포인트 파마슈티칼스, 엘엘씨 | 신규 약제 |
| UA95454C2 (uk) | 2005-07-15 | 2011-08-10 | Амр Текнолоджи, Інк. | Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну |
| CA2606004A1 (en) | 2005-08-02 | 2007-02-08 | Neurogen Corporation | Dipiperazinyl ketones and related analogues |
| CN101410385B (zh) * | 2006-03-28 | 2011-08-24 | 高点制药有限责任公司 | 具有组胺h3受体活性的苯并噻唑类 |
| CA2653062A1 (en) * | 2006-05-23 | 2007-11-29 | Transtech Pharma, Inc. | 6- (4-cyclopropylpiperazin-1-yl) -2 ' -methyl- [3, 4 ' ] -bipyridine and its use as a medicament |
| DK2079732T3 (da) | 2006-05-29 | 2012-01-23 | High Point Pharmaceuticals Llc | 3-(1,3-benzodioxol-5-yl)-6-(4-cyclopropylpiperazin-1-yl)-pyridazin, dets salte og solvater og dets anvendelse som histamin H3-receptorantagonister |
| EP2014656A3 (en) * | 2007-06-11 | 2011-08-24 | High Point Pharmaceuticals, LLC | New heteocyclic h3 antagonists |
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2007
- 2007-05-22 DK DK07729379.3T patent/DK2079732T3/da active
- 2007-05-22 EP EP07729379A patent/EP2079732B9/en active Active
- 2007-05-22 EP EP11182795A patent/EP2402324A1/en not_active Withdrawn
- 2007-05-22 AU AU2007267197A patent/AU2007267197B2/en not_active Ceased
- 2007-05-22 RS RS20120078A patent/RS52234B/sr unknown
- 2007-05-22 AT AT07729379T patent/ATE538116T1/de active
- 2007-05-22 EA EA200870586A patent/EA016026B1/ru not_active IP Right Cessation
- 2007-05-22 CA CA2659570A patent/CA2659570C/en not_active Expired - Fee Related
- 2007-05-22 JP JP2009512547A patent/JP5694661B2/ja not_active Expired - Fee Related
- 2007-05-22 US US12/302,132 patent/US8378097B2/en not_active Expired - Fee Related
- 2007-05-22 MX MX2008014766A patent/MX2008014766A/es active IP Right Grant
- 2007-05-22 CN CN2011101822989A patent/CN102295606A/zh active Pending
- 2007-05-22 PL PL07729379T patent/PL2079732T3/pl unknown
- 2007-05-22 CN CNA2007800197395A patent/CN101460487A/zh active Pending
- 2007-05-22 NZ NZ571972A patent/NZ571972A/en not_active IP Right Cessation
- 2007-05-22 WO PCT/EP2007/054940 patent/WO2007137968A1/en not_active Ceased
- 2007-05-22 BR BRPI0711370-6A patent/BRPI0711370A2/pt not_active IP Right Cessation
- 2007-05-22 KR KR1020087028536A patent/KR20090040259A/ko not_active Ceased
- 2007-05-22 SG SG201004699-3A patent/SG163547A1/en unknown
- 2007-05-22 SI SI200730845T patent/SI2079732T1/sl unknown
- 2007-05-22 PT PT07729379T patent/PT2079732E/pt unknown
- 2007-05-22 ES ES07729379T patent/ES2375872T3/es active Active
- 2007-05-22 HR HR20120227T patent/HRP20120227T1/hr unknown
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- 2008-10-12 IL IL194681A patent/IL194681A/en not_active IP Right Cessation
- 2008-10-13 ZA ZA2008/08730A patent/ZA200808730B/en unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| ES2375872T3 (es) | 2012-03-07 |
| ATE538116T1 (de) | 2012-01-15 |
| CA2659570A1 (en) | 2007-12-06 |
| MX2008014766A (es) | 2009-03-06 |
| NZ571972A (en) | 2011-09-30 |
| EP2079732B1 (en) | 2011-12-21 |
| US20090176793A1 (en) | 2009-07-09 |
| RS52234B (sr) | 2012-10-31 |
| KR20090040259A (ko) | 2009-04-23 |
| WO2007137968A1 (en) | 2007-12-06 |
| ZA200808730B (en) | 2010-02-24 |
| EA200870586A1 (ru) | 2009-10-30 |
| PL2079732T3 (pl) | 2012-05-31 |
| CN101460487A (zh) | 2009-06-17 |
| DK2079732T3 (da) | 2012-01-23 |
| HRP20120227T1 (hr) | 2012-04-30 |
| PT2079732E (pt) | 2012-02-02 |
| JP2009538861A (ja) | 2009-11-12 |
| AU2007267197A1 (en) | 2007-12-06 |
| EP2079732A1 (en) | 2009-07-22 |
| CA2659570C (en) | 2015-10-06 |
| AU2007267197B2 (en) | 2011-12-01 |
| US8378097B2 (en) | 2013-02-19 |
| EP2402324A1 (en) | 2012-01-04 |
| CY1112455T1 (el) | 2015-12-09 |
| ES2375872T9 (es) | 2012-07-19 |
| EA016026B1 (ru) | 2012-01-30 |
| IL194681A (en) | 2013-09-30 |
| BRPI0711370A2 (pt) | 2011-11-01 |
| SG163547A1 (en) | 2010-08-30 |
| JP5694661B2 (ja) | 2015-04-01 |
| SI2079732T1 (sl) | 2012-03-30 |
| EP2079732B9 (en) | 2012-03-21 |
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