CN102264391A - 工程化抗il-13抗体、组合物、方法和用途 - Google Patents

工程化抗il-13抗体、组合物、方法和用途 Download PDF

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Publication number
CN102264391A
CN102264391A CN2009801424060A CN200980142406A CN102264391A CN 102264391 A CN102264391 A CN 102264391A CN 2009801424060 A CN2009801424060 A CN 2009801424060A CN 200980142406 A CN200980142406 A CN 200980142406A CN 102264391 A CN102264391 A CN 102264391A
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China
Prior art keywords
antibody
seq
variable region
people
heavy chain
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CN2009801424060A
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Chinese (zh)
Inventor
R·V·斯万森
E·赤
G·拉胡纳坦
S·赵
J·弗兰森
W·科尔迪尔
J·C·阿尔马格罗
L·云
J·吉尔斯-科马
K·T·奥奈尔
J·M·卡通
H·M·周
A·V·特普利亚科夫
Y·冯
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Janssen Biotech Inc
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Centocor Ortho Biotech Inc
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Publication of CN102264391A publication Critical patent/CN102264391A/zh
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    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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CN2009801424060A 2008-08-20 2009-08-11 工程化抗il-13抗体、组合物、方法和用途 Pending CN102264391A (zh)

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US9047208P 2008-08-20 2008-08-20
US61/090472 2008-08-20
US9723208P 2008-09-16 2008-09-16
US61/097232 2008-09-16
PCT/US2009/053425 WO2010021874A2 (en) 2008-08-20 2009-08-11 Engineered anti-il-13 antibodies, compositions, methods and uses

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