UY32060A - Anticuerpos anti-il-13 obtenidos mediante ingeniería, composiciones , métodos y usos - Google Patents

Anticuerpos anti-il-13 obtenidos mediante ingeniería, composiciones , métodos y usos

Info

Publication number
UY32060A
UY32060A UY0001032060A UY32060A UY32060A UY 32060 A UY32060 A UY 32060A UY 0001032060 A UY0001032060 A UY 0001032060A UY 32060 A UY32060 A UY 32060A UY 32060 A UY32060 A UY 32060A
Authority
UY
Uruguay
Prior art keywords
methods
engineering
compositions
antibodies obtained
antibodies
Prior art date
Application number
UY0001032060A
Other languages
English (en)
Inventor
Karyn T O Neil
Ronald V Swanson
Chi Ellen
Raghunathan Gopalan
Zhao Shanrong
Fransson Johan
Cordier Wendy
Juan C Almagro
Hyun Linus
Jill Giles-Komar
Jill M Carton
Hong Mimi Zhou
Alexey V Teplyakov
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of UY32060A publication Critical patent/UY32060A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2319/00—Fusion polypeptide
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    • G—PHYSICS
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    • G01N2333/5437—IL-13

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  • General Health & Medical Sciences (AREA)
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Abstract

La presente invención se refiere a anticuerpos inmunoespecíficos para la proteína interleucina-13 humana (IL-13) o fragmentos de la misma, así como también los métodos para preparar y usar los mismos, incluyendo indicaciones terapéuticas.
UY0001032060A 2008-08-20 2009-08-19 Anticuerpos anti-il-13 obtenidos mediante ingeniería, composiciones , métodos y usos UY32060A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US9723208P 2008-09-16 2008-09-16

Publications (1)

Publication Number Publication Date
UY32060A true UY32060A (es) 2010-02-26

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Application Number Title Priority Date Filing Date
UY0001032060A UY32060A (es) 2008-08-20 2009-08-19 Anticuerpos anti-il-13 obtenidos mediante ingeniería, composiciones , métodos y usos

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US (2) US8399630B2 (es)
EP (1) EP2328615A2 (es)
JP (2) JP2012506695A (es)
KR (1) KR20110043786A (es)
CN (1) CN102264391A (es)
AR (1) AR073088A1 (es)
AU (1) AU2009283008A1 (es)
BR (1) BRPI0917370A2 (es)
CA (1) CA2734645A1 (es)
CO (1) CO6341573A2 (es)
CR (1) CR20110152A (es)
EA (1) EA201170357A1 (es)
EC (1) ECSP11010840A (es)
IL (1) IL211087A0 (es)
MX (1) MX2011001909A (es)
NI (1) NI201100040A (es)
NZ (1) NZ591098A (es)
UY (1) UY32060A (es)
WO (1) WO2010021874A2 (es)
ZA (1) ZA201102081B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
WO2010021874A2 (en) * 2008-08-20 2010-02-25 Centocor Ortho Biotech Inc. Engineered anti-il-13 antibodies, compositions, methods and uses
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
US8580714B2 (en) * 2009-10-14 2013-11-12 Janssen Biotech, Inc. Methods of affinity maturing antibodies
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