CA2734645A1 - Engineered anti-il-13 antibodies, compositions, methods and uses - Google Patents

Engineered anti-il-13 antibodies, compositions, methods and uses Download PDF

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Publication number
CA2734645A1
CA2734645A1 CA2734645A CA2734645A CA2734645A1 CA 2734645 A1 CA2734645 A1 CA 2734645A1 CA 2734645 A CA2734645 A CA 2734645A CA 2734645 A CA2734645 A CA 2734645A CA 2734645 A1 CA2734645 A1 CA 2734645A1
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CA
Canada
Prior art keywords
antibody
seq
human
binding
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2734645A
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English (en)
French (fr)
Inventor
Ronald V. Swanson
Ellen Chi
Gopalan Raghunathan
Shanrong Zhao
Johan Fransson
Wendy Cordier
Juan C. Almagro
Linus Hyun
Jill Giles-Komar
Karyn T. O'neil
Jill M. Carton
Hong Mimi Zhou
Alexey V. Teplyakov
Yiqing Feng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of CA2734645A1 publication Critical patent/CA2734645A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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  • Proteomics, Peptides & Aminoacids (AREA)
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CA2734645A 2008-08-20 2009-08-11 Engineered anti-il-13 antibodies, compositions, methods and uses Abandoned CA2734645A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US61/090,472 2008-08-20
US9723208P 2008-09-16 2008-09-16
US61/097,232 2008-09-16
PCT/US2009/053425 WO2010021874A2 (en) 2008-08-20 2009-08-11 Engineered anti-il-13 antibodies, compositions, methods and uses

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CA2734645A1 true CA2734645A1 (en) 2010-02-25

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CA2734645A Abandoned CA2734645A1 (en) 2008-08-20 2009-08-11 Engineered anti-il-13 antibodies, compositions, methods and uses

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US (2) US8399630B2 (enExample)
EP (1) EP2328615A2 (enExample)
JP (2) JP2012506695A (enExample)
KR (1) KR20110043786A (enExample)
CN (1) CN102264391A (enExample)
AR (1) AR073088A1 (enExample)
AU (1) AU2009283008A1 (enExample)
BR (1) BRPI0917370A2 (enExample)
CA (1) CA2734645A1 (enExample)
CO (1) CO6341573A2 (enExample)
CR (1) CR20110152A (enExample)
EA (1) EA201170357A1 (enExample)
EC (1) ECSP11010840A (enExample)
IL (1) IL211087A0 (enExample)
MX (1) MX2011001909A (enExample)
NI (1) NI201100040A (enExample)
NZ (1) NZ591098A (enExample)
UY (1) UY32060A (enExample)
WO (1) WO2010021874A2 (enExample)
ZA (1) ZA201102081B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9758591B2 (en) 2012-08-24 2017-09-12 The Regents Of The University Of California Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
US10688181B2 (en) 2016-06-27 2020-06-23 The Regents Of The University Of California Cancer treatment combinations

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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