NI201100040A - Anticuerpos anti-il-13 modificados, composiciones, métodos y usos. - Google Patents

Anticuerpos anti-il-13 modificados, composiciones, métodos y usos.

Info

Publication number
NI201100040A
NI201100040A NI201100040A NI201100040A NI201100040A NI 201100040 A NI201100040 A NI 201100040A NI 201100040 A NI201100040 A NI 201100040A NI 201100040 A NI201100040 A NI 201100040A NI 201100040 A NI201100040 A NI 201100040A
Authority
NI
Nicaragua
Prior art keywords
methods
antibodies
compositions
modified anti
fragment
Prior art date
Application number
NI201100040A
Other languages
English (en)
Spanish (es)
Inventor
V Swanson Ronald
Chi Ellen
Raghunathan Gopalan
Zhao Shanrong
Fransson Johan
Cordier Wendy
C Almagro Juan
Hyun Linus
Giles-Komar Jill
T O'neil Karyn
M Carton Jill
Mimi Zhou Hong
V Teplyakov Alexey
Feng Yiqing
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of NI201100040A publication Critical patent/NI201100040A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
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    • C07K2317/55Fab or Fab'
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/5437IL-13

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  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
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NI201100040A 2008-08-20 2011-02-18 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos. NI201100040A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US9723208P 2008-09-16 2008-09-16

Publications (1)

Publication Number Publication Date
NI201100040A true NI201100040A (es) 2011-09-03

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Application Number Title Priority Date Filing Date
NI201100040A NI201100040A (es) 2008-08-20 2011-02-18 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos.

Country Status (20)

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US (2) US8399630B2 (enExample)
EP (1) EP2328615A2 (enExample)
JP (2) JP2012506695A (enExample)
KR (1) KR20110043786A (enExample)
CN (1) CN102264391A (enExample)
AR (1) AR073088A1 (enExample)
AU (1) AU2009283008A1 (enExample)
BR (1) BRPI0917370A2 (enExample)
CA (1) CA2734645A1 (enExample)
CO (1) CO6341573A2 (enExample)
CR (1) CR20110152A (enExample)
EA (1) EA201170357A1 (enExample)
EC (1) ECSP11010840A (enExample)
IL (1) IL211087A0 (enExample)
MX (1) MX2011001909A (enExample)
NI (1) NI201100040A (enExample)
NZ (1) NZ591098A (enExample)
UY (1) UY32060A (enExample)
WO (1) WO2010021874A2 (enExample)
ZA (1) ZA201102081B (enExample)

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US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
NZ591098A (en) * 2008-08-20 2012-08-31 Centocor Ortho Biotech Inc Engineered anti-il-13 antibodies, compositions, methods and uses
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
JP2013508287A (ja) * 2009-10-14 2013-03-07 ヤンセン バイオテツク,インコーポレーテツド 抗体を親和性成熟する方法
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
WO2013019730A1 (en) 2011-07-29 2013-02-07 The Washington University Antibodies to tip-1 and grp78
KR101935088B1 (ko) 2012-08-24 2019-01-04 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Ror1 암을 치료하고 전이를 저해하는데 이용을 위한 항체와 백신
US20140271462A1 (en) 2013-03-13 2014-09-18 Imaginab, Inc. Antigen binding constructs to cd8
EP3172222A4 (en) 2014-07-24 2018-03-21 Washington University Compositions targeting radiation-induced molecules and methods of use thereof
CN115960230A (zh) 2015-08-07 2023-04-14 伊麦吉纳博公司 靶向分子的抗原结合构建体
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