CN102264378A - 包含桔梗根提取物或桔梗皂甙组分的用于预防或治疗丙型肝炎的药物组合物 - Google Patents

包含桔梗根提取物或桔梗皂甙组分的用于预防或治疗丙型肝炎的药物组合物 Download PDF

Info

Publication number
CN102264378A
CN102264378A CN2010800037472A CN201080003747A CN102264378A CN 102264378 A CN102264378 A CN 102264378A CN 2010800037472 A CN2010800037472 A CN 2010800037472A CN 201080003747 A CN201080003747 A CN 201080003747A CN 102264378 A CN102264378 A CN 102264378A
Authority
CN
China
Prior art keywords
extract
saponin
pharmaceutical composition
hcv
radix platycodonis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800037472A
Other languages
English (en)
Chinese (zh)
Inventor
金钟宇
李常旭
朴相珍
慎重哲
梁栽源
林钟焕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B&c Biopharmaceutical Co ltd
Original Assignee
B&c Biopharmaceutical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B&c Biopharmaceutical Co ltd filed Critical B&c Biopharmaceutical Co ltd
Publication of CN102264378A publication Critical patent/CN102264378A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00—Compounds of titanium
    • C01G23/04—Oxides; Hydroxides
    • C01G23/047—Titanium dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
    • H10F10/00—Individual photovoltaic cells, e.g. solar cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E10/00—Energy generation through renewable energy sources
    • Y02E10/50—Photovoltaic [PV] energy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nutrition Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Manufacturing & Machinery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CN2010800037472A 2009-01-23 2010-01-21 包含桔梗根提取物或桔梗皂甙组分的用于预防或治疗丙型肝炎的药物组合物 Pending CN102264378A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20090006078 2009-01-23
KR10-2009-0006078 2009-01-23
KR1020090100092A KR101162710B1 (ko) 2009-01-23 2009-10-21 도라지 추출물 또는 도라지 사포닌 화합물을 함유하는 ｃ형 간염의 예방 또는 치료용 약학적 조성물
KR10-2009-0100092 2009-10-21
PCT/KR2010/000376 WO2010085091A2 (en) 2009-01-23 2010-01-21 Pharmaceutical composition for preventing or treating hepatitis c, comprising the roots extract of platycodon grandiflorum or platycodon grandiflorum saponin components

Publications (1)

Publication Number Publication Date
CN102264378A true CN102264378A (zh) 2011-11-30

Family

ID=42753875

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800037472A Pending CN102264378A (zh) 2009-01-23 2010-01-21 包含桔梗根提取物或桔梗皂甙组分的用于预防或治疗丙型肝炎的药物组合物

Country Status (8)

Country Link
US (1) US20110274656A1 (enExample)
EP (1) EP2389185A2 (enExample)
JP (1) JP2012515773A (enExample)
KR (1) KR101162710B1 (enExample)
CN (1) CN102264378A (enExample)
AU (1) AU2010207093A1 (enExample)
CA (1) CA2748942A1 (enExample)
WO (1) WO2010085091A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021110101A1 (zh) * 2019-12-03 2021-06-10 延边大学 一种去芹糖桔梗皂苷d的制备方法及其应用
CN113116912A (zh) * 2021-06-07 2021-07-16 长春中医药大学 去芹糖桔梗皂苷d在制备预防和/或治疗肝癌药物中的应用

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101251589B1 (ko) * 2012-09-27 2013-04-08 한국화학연구원 도라지 또는 도라지 추출물로부터의 순도 및 유효 사포닌 함량이 증가된 조사포닌 조성물의 제조방법
CN103768078B (zh) * 2012-10-22 2019-02-05 北京大学 三萜衍生物及其抗流感用途
WO2014193088A1 (ko) * 2013-05-31 2014-12-04 동국대학교 산학협력단 포도근 추출물 또는 이의 분획물을 유효성분으로 포함하는 c형 간염의 예방 또는 치료용 조성물
KR101475630B1 (ko) 2013-05-31 2014-12-22 동국대학교 산학협력단 포도근 추출물 또는 이의 분획물을 유효성분으로 포함하는 c형 간염의 예방 또는 치료용 조성물
JP6095591B2 (ja) * 2014-02-12 2017-03-15 株式会社アンチエイジング・プロ 山芋抽出物の製造方法
KR101705545B1 (ko) 2015-02-06 2017-02-13 주식회사 웰파이토 도라지 발효물을 유효성분으로 포함하는 기관지질환, 면역증강 및 항비만 예방 효능의 건강차 조성물
KR101880934B1 (ko) 2017-09-14 2018-07-23 주식회사 아오스 도라지에서 추출된 도라지 사포닌 농축물을 함유하는 약학적 조성물의 제조방법
WO2020085799A1 (ko) * 2018-10-23 2020-04-30 주식회사 온사이언스 도라지 사포닌을 포함하는 표준화된 도라지 추출물 또는 막분리 도라지 사포닌 추출물을 함유하는 간질환의 예방 또는 치료용 약학적 조성물 및 간기능 개선용 건강기능식품
CN110754573A (zh) * 2019-12-04 2020-02-07 金陵科技学院 一种桔梗皂苷d饲料添加剂及其应用、制备方法
KR102611611B1 (ko) 2023-03-21 2023-12-11 주식회사 아오스 도라지에서 추출된 도라지 사포닌 농축물을 함유하는 약학적 조성물의 제조방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1397560A (zh) * 2002-08-13 2003-02-19 吉林天药科技股份有限公司 从桔梗中提取桔梗总皂苷和单体桔梗皂苷d的方法及其医药新用途和中药制剂
CN1566137A (zh) * 2003-07-04 2005-01-19 深圳亿胜医药科技发展有限公司 桔梗总皂苷生产工艺
CN1850851A (zh) * 2006-05-24 2006-10-25 浙江大学 利用弱极性大孔树脂制备桔梗总皂苷提取物的方法及用途
CN101240005A (zh) * 2007-10-29 2008-08-13 吉林农业大学 一种从桔梗中制备桔梗皂苷d的方法及其在抗癌药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849282A (en) * 1990-05-09 1998-12-15 Otsuka Pharmaceutical Co., Ltd. Method of treating colon, renal, and lung carcinomas with γ-interferon and Ser71 !-interleukin-1β
US5405837A (en) * 1993-05-18 1995-04-11 Indiana University Foundation Method for the treatment of neoplastic disease utilizing tiazofurin and ribavirin
KR20050021026A (ko) 2001-06-15 2005-03-07 주식회사 장생도라지 장생도라지 추출물을 포함하는 면역계의 이상으로부터발생하는 질병의 예방 및 치료용 약제학적 조성물
KR20030021072A (ko) * 2001-09-05 2003-03-12 주식회사 장생도라지 간 질병의 예방 및 치료용 간장질환용제
KR100564927B1 (ko) * 2003-09-04 2006-03-30 비타민하우스알앤비티(주) 플라티코딘을 유효성분으로 함유하는 항암제
KR100643877B1 (ko) * 2004-07-19 2006-11-10 주식회사 장생도라지 장생도라지 추출물을 유효성분으로 함유하는 알코올성간질환의 억제, 치료용 약학적 조성물 및 알코올대사촉진용 조성물
JPWO2006046674A1 (ja) * 2004-10-25 2008-05-22 中外製薬株式会社 Ｃ型肝炎ウイルス感染症の予防および治療剤
KR20050043880A (ko) * 2005-04-27 2005-05-11 김성호 간염억제활성을 갖는 생약 제제 추출물
KR100543354B1 (ko) * 2005-05-17 2006-01-20 김성호 간염억제활성을 갖는 생약재 추출물
JP4794944B2 (ja) * 2005-08-11 2011-10-19 博光 熊田 Ｃ型肝炎に対するインターフェロン／リバビリン併用療法の有効性の判定方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1397560A (zh) * 2002-08-13 2003-02-19 吉林天药科技股份有限公司 从桔梗中提取桔梗总皂苷和单体桔梗皂苷d的方法及其医药新用途和中药制剂
CN1566137A (zh) * 2003-07-04 2005-01-19 深圳亿胜医药科技发展有限公司 桔梗总皂苷生产工艺
CN1850851A (zh) * 2006-05-24 2006-10-25 浙江大学 利用弱极性大孔树脂制备桔梗总皂苷提取物的方法及用途
CN101240005A (zh) * 2007-10-29 2008-08-13 吉林农业大学 一种从桔梗中制备桔梗皂苷d的方法及其在抗癌药物中的应用

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
付文卫等: "桔梗中三萜皂苷的分离与结构鉴定", 《中国药物化学杂志》 *
张娟等: "皂苷的提取方法及含量测定研究进展", 《中国现代中药》 *
杨献文等: "桔梗总皂苷的制备工艺研究", 《沈阳药科大学学报》 *
郭文杰等: "桔梗中三萜皂苷类化学成分研究进展", 《中国药学杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021110101A1 (zh) * 2019-12-03 2021-06-10 延边大学 一种去芹糖桔梗皂苷d的制备方法及其应用
CN113116912A (zh) * 2021-06-07 2021-07-16 长春中医药大学 去芹糖桔梗皂苷d在制备预防和/或治疗肝癌药物中的应用

Also Published As

Publication number Publication date
WO2010085091A3 (en) 2010-11-25
KR20100086923A (ko) 2010-08-02
JP2012515773A (ja) 2012-07-12
EP2389185A2 (en) 2011-11-30
CA2748942A1 (en) 2010-07-29
US20110274656A1 (en) 2011-11-10
WO2010085091A2 (en) 2010-07-29
KR101162710B1 (ko) 2012-07-05
AU2010207093A1 (en) 2011-07-21

Similar Documents

Publication Publication Date Title
CN102264378A (zh) 包含桔梗根提取物或桔梗皂甙组分的用于预防或治疗丙型肝炎的药物组合物
Wu et al. In vivo and in vitro antiviral activity of hyperoside extracted from Abelmoschus manihot (L) medik
Li et al. Glycyrrhizic acid in the treatment of liver diseases: literature review
CN101392015B (zh) 山茶种子中的三萜皂苷及其制备方法和医药用途
Yang et al. Hepatoprotective and inhibiting HBV effects of polysaccharides from roots of Sophora flavescens
CN115215914A (zh) 核苷类似物及其用途
Wang et al. Therapeutic potential of oleanolic acid in liver diseases
CN103880910A (zh) 一种环黄芪醇的制备方法及其用途
JP2013508425A (ja) Ｂｉ２０１３３５、インターフェロンアルファおよびリバビリンを含むｈｃｖの併用療法のための投薬処置計画
KR101584885B1 (ko) C형 간염 바이러스의 게놈 복제의 선택적 저해 활성을 갖는 레스베라트롤 다량체 및 이의 용도
CN103880856B (zh) 没药烷型倍半萜类衍生物及其药物组合物和其在制药中的应用
CN102223888A (zh) 富含甘草素的提取物或自其衍生的甘草素用于增加胆汁流、利胆作用以及用于预防和治疗胆汁淤积性肝病的用途
CN103096885B (zh) 不饱和脂肪酸用于抑制病毒复制和/或感染的用途
JP7376871B2 (ja) センソ及びゴオウの医薬用途
CN105017354B (zh) 一种环烯醚萜类化合物及其制备方法、制剂与应用
WO2006046674A1 (ja) Ｃ型肝炎ウイルス感染症の予防および治療剤
CN110669028B (zh) 大象肠道来源的放线菌的丁烯酸内酯类化合物及其应用
KR102694541B1 (ko) 플로로탄닌을 유효성분으로 포함하는 항바이러스제
CN106822152B (zh) 一种药物组合物及其应用
WO1996036346A1 (en) Water-soluble extract originating in feather cockscomb
CN101602787B (zh) 泽泻醇a衍生物,其药物组合物及其制备方法和用途
AU2006270662B2 (en) A composition comprising an extract of tiarella polyphylla and tiarellic acid isolated therefrom having antiinflammatory, antiallergic and antiasthmatic activity
JP2012250940A (ja) Ｃ型肝炎の予防、治療又は改善用組成物
CN101717425B (zh) 11,23,24-三-氧-丁酰基泽泻醇a,其药物组合物及其用途
CN117586262A (zh) 核苷类似物及其用途

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20111130