CN102127078A - Janus激酶3的杂环类抑制剂 - Google Patents
Janus激酶3的杂环类抑制剂 Download PDFInfo
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- CN102127078A CN102127078A CN2010106153197A CN201010615319A CN102127078A CN 102127078 A CN102127078 A CN 102127078A CN 2010106153197 A CN2010106153197 A CN 2010106153197A CN 201010615319 A CN201010615319 A CN 201010615319A CN 102127078 A CN102127078 A CN 102127078A
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| CN111566095A (zh) * | 2017-11-03 | 2020-08-21 | 阿克拉瑞斯治疗股份有限公司 | 被取代的吡咯并吡啶jak抑制剂及其制造方法和使用方法 |
| WO2020182159A1 (zh) * | 2019-03-14 | 2020-09-17 | 上海华汇拓医药科技有限公司 | Jak激酶抑制剂及其制备方法和在医药领域的应用 |
| CN116323612A (zh) * | 2020-07-02 | 2023-06-23 | 因赛特公司 | 作为jak2 v617f抑制剂的三环脲化合物 |
| US11787807B2 (en) | 2018-06-15 | 2023-10-17 | Janssen Pharmaceutica Nv | Small molecule inhibitors of the JAK family of kinases |
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| TWI916379B (zh) | 2020-07-02 | 2026-03-01 | 美商英塞特公司 | 作為jak2 v617f抑制劑之三環脲化合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2251341A1 (en) * | 2005-07-14 | 2010-11-17 | Astellas Pharma Inc. | Heterocyclic Janus kinase 3 inhibitors |
| WO2007007919A2 (en) | 2005-07-14 | 2007-01-18 | Astellas Pharma Inc. | Heterocyclic janus kinase 3 inhibitors |
| EP2455382B1 (en) | 2005-12-13 | 2016-10-26 | Incyte Holdings Corporation | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors |
| JPWO2008053652A1 (ja) | 2006-11-02 | 2010-02-25 | 塩野義製薬株式会社 | ヒドロキシアダマンタンアミンの製造方法 |
| EP2123651A4 (en) * | 2007-01-12 | 2011-05-04 | Astellas Pharma Inc | CONDENSED PYRIDINE COMPOUND |
| EP3070090B1 (en) | 2007-06-13 | 2018-12-12 | Incyte Holdings Corporation | Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile |
| US8541426B2 (en) | 2007-07-11 | 2013-09-24 | Pfizer Inc. | Pharmaceutical compositions and methods of treating dry eye disorders |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11827638B2 (en) | 2016-12-16 | 2023-11-28 | Janssen Pharmaceutica Nv | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases |
| US12202831B2 (en) | 2016-12-16 | 2025-01-21 | Janssen Pharmaceutica Nv | Small molecule inhibitors of the JAK family of kinases |
| CN111566095A (zh) * | 2017-11-03 | 2020-08-21 | 阿克拉瑞斯治疗股份有限公司 | 被取代的吡咯并吡啶jak抑制剂及其制造方法和使用方法 |
| US11787807B2 (en) | 2018-06-15 | 2023-10-17 | Janssen Pharmaceutica Nv | Small molecule inhibitors of the JAK family of kinases |
| WO2020182159A1 (zh) * | 2019-03-14 | 2020-09-17 | 上海华汇拓医药科技有限公司 | Jak激酶抑制剂及其制备方法和在医药领域的应用 |
| CN113631557A (zh) * | 2019-03-14 | 2021-11-09 | 上海华汇拓医药科技有限公司 | Jak激酶抑制剂及其制备方法和在医药领域的应用 |
| CN113631557B (zh) * | 2019-03-14 | 2024-03-15 | 上海华汇拓医药科技有限公司 | Jak激酶抑制剂及其制备方法和在医药领域的应用 |
| US12398141B2 (en) | 2019-03-14 | 2025-08-26 | Shanghai Synergy Pharmaceutical Sciences Co., Ltd | JAK kinase inhibitor, preparation method for same, and applications thereof in field of medicine |
| CN116323612A (zh) * | 2020-07-02 | 2023-06-23 | 因赛特公司 | 作为jak2 v617f抑制剂的三环脲化合物 |
| TWI916379B (zh) | 2020-07-02 | 2026-03-01 | 美商英塞特公司 | 作為jak2 v617f抑制劑之三環脲化合物 |
| US12390451B2 (en) | 2021-03-11 | 2025-08-19 | Janssen Pharmaceutica Nv | Small molecule inhibitor of the JAK family of kinases |
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