CN102105153B - Sglt2抑制剂的医药用途和含该抑制剂的组合物 - Google Patents

Sglt2抑制剂的医药用途和含该抑制剂的组合物 Download PDF

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Publication number
CN102105153B
CN102105153B CN200980128978.3A CN200980128978A CN102105153B CN 102105153 B CN102105153 B CN 102105153B CN 200980128978 A CN200980128978 A CN 200980128978A CN 102105153 B CN102105153 B CN 102105153B
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China
Prior art keywords
inhibitor
sglt2
uric acid
hyperuricemia
dapagliflozin
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Expired - Fee Related
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CN200980128978.3A
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English (en)
Chinese (zh)
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CN102105153A (zh
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B·R·莱斯利
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AstraZeneca AB
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Bristol Myers Squibb Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
CN200980128978.3A 2008-05-22 2009-05-15 Sglt2抑制剂的医药用途和含该抑制剂的组合物 Expired - Fee Related CN102105153B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5535208P 2008-05-22 2008-05-22
US61/055352 2008-05-22
PCT/US2009/044156 WO2009143020A1 (en) 2008-05-22 2009-05-15 Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same

Publications (2)

Publication Number Publication Date
CN102105153A CN102105153A (zh) 2011-06-22
CN102105153B true CN102105153B (zh) 2014-03-05

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CN200980128978.3A Expired - Fee Related CN102105153B (zh) 2008-05-22 2009-05-15 Sglt2抑制剂的医药用途和含该抑制剂的组合物

Country Status (9)

Country Link
US (1) US8791077B2 (enExample)
EP (2) EP2291189B1 (enExample)
JP (2) JP5820269B2 (enExample)
CN (1) CN102105153B (enExample)
BR (1) BRPI0913129A2 (enExample)
CA (1) CA2725047A1 (enExample)
ES (1) ES2526930T3 (enExample)
MX (1) MX2010012656A (enExample)
WO (1) WO2009143020A1 (enExample)

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WO2014149789A1 (en) * 2013-03-15 2014-09-25 Janssen Pharmaceutica Nv Combination of canagliflozin and probenecid for the treament of hyperuricemia
ES2959444T3 (es) 2013-04-04 2024-02-26 Boehringer Ingelheim Vetmedica Gmbh Tratamiento de trastornos metabólicos en animales equinos
EP3082829B1 (en) 2013-12-17 2021-02-17 Boehringer Ingelheim Vetmedica GmbH Sglt2 inhibitors for the treatment of metabolic disorders in feline animals
EA032558B1 (ru) 2014-01-23 2019-06-28 Бёрингер Ингельхайм Ветмедика Гмбх Лечение метаболических расстройств у представителей собачьих
DK3721882T3 (da) 2014-04-01 2024-10-21 Boehringer Ingelheim Vetmedica Gmbh Behandling af hypofyse pars intermedia-dysfunktion hos hestedyr
KR102539788B1 (ko) 2014-09-25 2023-06-07 베링거잉겔하임베트메디카게엠베하 말과 동물의 대사 장애를 예방하기 위한 sglt2 억제제와 도파민 작용제의 병용 치료
MX389367B (es) * 2015-08-27 2025-03-20 Boehringer Ingelheim Vetmedica Gmbh Composiciones farmaceuticas liquidas que comprenden inhibidores de sglt-2.
KR101863604B1 (ko) * 2016-04-08 2018-06-04 한국 한의학 연구원 익지 추출물을 유효성분으로 함유하는 고요산혈증 또는 고요산혈증 관련 대사 장애의 예방, 개선 또는 치료용 조성물
US11020412B2 (en) 2017-03-16 2021-06-01 Inventia Healthcare Limited Pharmaceutical composition comprising dapagliflozin
WO2019087239A1 (ja) * 2017-10-30 2019-05-09 合同会社カルナヘルスサポート 腎症治療剤
JPWO2019092770A1 (ja) * 2017-11-07 2019-11-14 合同会社カルナヘルスサポート 網膜疾患治療剤
WO2020070539A1 (en) * 2018-10-01 2020-04-09 Astrazeneca Ab Compositions for reducing serum uric acid
JP2022511800A (ja) 2018-12-06 2022-02-01 アースローシ セラピューティクス，インク． 痛風または高尿酸血症を処置または予防するための化合物の結晶形態
CN113164439A (zh) 2018-12-06 2021-07-23 安索治疗公司 用于治疗或预防痛风或高尿酸血症的方法
WO2020178821A1 (en) * 2019-03-03 2020-09-10 Algatechnologies Ltd. Compositions comprising algae powder and uses thereof
JP6831961B2 (ja) * 2019-10-23 2021-02-24 株式会社カルナヘルスサポート 網膜疾患治療剤
BR112022010385A2 (pt) 2019-11-28 2022-08-23 Boehringer Ingelheim Vetmedica Gmbh Uso de inibidores de sglt-2 na secagem de mamíferos não humanos
KR20230024354A (ko) * 2020-06-10 2023-02-20 아쓰로시 테라퓨틱스, 인크. 만성 신장 질환을 치료 또는 예방하는 방법

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Also Published As

Publication number Publication date
EP2291189A1 (en) 2011-03-09
CN102105153A (zh) 2011-06-22
EP2668953A1 (en) 2013-12-04
MX2010012656A (es) 2010-12-20
WO2009143020A1 (en) 2009-11-26
EP2291189B1 (en) 2014-10-01
JP2011520965A (ja) 2011-07-21
CA2725047A1 (en) 2009-11-26
ES2526930T3 (es) 2015-01-16
JP2014205700A (ja) 2014-10-30
US8791077B2 (en) 2014-07-29
US20110065658A1 (en) 2011-03-17
BRPI0913129A2 (pt) 2016-01-05
JP5820269B2 (ja) 2015-11-24

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