ES2526930T3 - Método para el tratamiento de la hiperuricemia empleando un inhibidor de SGLT2 y composición que contiene el mismo - Google Patents
Método para el tratamiento de la hiperuricemia empleando un inhibidor de SGLT2 y composición que contiene el mismo Download PDFInfo
- Publication number
- ES2526930T3 ES2526930T3 ES09751249.5T ES09751249T ES2526930T3 ES 2526930 T3 ES2526930 T3 ES 2526930T3 ES 09751249 T ES09751249 T ES 09751249T ES 2526930 T3 ES2526930 T3 ES 2526930T3
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- Prior art keywords
- inhibitor
- sglt2
- hyperuricemia
- sglt2 inhibitor
- dapagliflozin
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- 210000000813 small intestine Anatomy 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229940121377 sodium-glucose co-transporter inhibitor Drugs 0.000 description 1
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- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
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- 229960005322 streptomycin Drugs 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
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- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960003329 sulfinpyrazone Drugs 0.000 description 1
- MBGGBVCUIVRRBF-UHFFFAOYSA-N sulfinpyrazone Chemical compound O=C1N(C=2C=CC=CC=2)N(C=2C=CC=CC=2)C(=O)C1CCS(=O)C1=CC=CC=C1 MBGGBVCUIVRRBF-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
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| US5535208P | 2008-05-22 | 2008-05-22 | |
| US55352P | 2008-05-22 | ||
| PCT/US2009/044156 WO2009143020A1 (en) | 2008-05-22 | 2009-05-15 | Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same |
Publications (1)
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|---|---|
| ES2526930T3 true ES2526930T3 (es) | 2015-01-16 |
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| EP (2) | EP2668953A1 (enExample) |
| JP (2) | JP5820269B2 (enExample) |
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| BR (1) | BRPI0913129A2 (enExample) |
| CA (1) | CA2725047A1 (enExample) |
| ES (1) | ES2526930T3 (enExample) |
| MX (1) | MX2010012656A (enExample) |
| WO (1) | WO2009143020A1 (enExample) |
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| US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
| US8163704B2 (en) | 2009-10-20 | 2012-04-24 | Novartis Ag | Glycoside derivatives and uses thereof |
| CA2801930A1 (en) | 2010-06-16 | 2011-12-22 | Takeda Pharmaceuticals U.S.A., Inc. | Novel modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors |
| US20140093563A1 (en) * | 2011-06-13 | 2014-04-03 | Ranbaxy Laboratories Limited | Febuxostat compositions |
| RU2014134845A (ru) * | 2012-01-27 | 2016-03-20 | Тейдзин Фарма Лимитед | Терапевтическое средство против диабета |
| WO2014149789A1 (en) * | 2013-03-15 | 2014-09-25 | Janssen Pharmaceutica Nv | Combination of canagliflozin and probenecid for the treament of hyperuricemia |
| EP2981269B9 (en) | 2013-04-04 | 2023-12-06 | Boehringer Ingelheim Vetmedica GmbH | Treatment of metabolic disorders in equine animals |
| PL3082829T3 (pl) | 2013-12-17 | 2021-09-06 | Boehringer Ingelheim Vetmedica Gmbh | Inhibitory sglt2 do leczenia zaburzeń metabolicznych u zwierząt kotowatych |
| PL3096765T3 (pl) | 2014-01-23 | 2019-05-31 | Boehringer Ingelheim Vetmedica Gmbh | Leczenie zaburzeń metabolicznych u zwierząt psowatych |
| KR102662473B1 (ko) | 2014-04-01 | 2024-05-03 | 베링거잉겔하임베트메디카게엠베하 | 말과 동물에서 대사 장애의 치료 |
| AU2015320975B2 (en) | 2014-09-25 | 2020-10-08 | Boehringer Ingelheim Vetmedica Gmbh | Combination treatment of SGLT2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals |
| NZ739429A (en) * | 2015-08-27 | 2023-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Liquid pharmaceutical compositions comprising sglt-2 inhibitors |
| KR101863604B1 (ko) * | 2016-04-08 | 2018-06-04 | 한국 한의학 연구원 | 익지 추출물을 유효성분으로 함유하는 고요산혈증 또는 고요산혈증 관련 대사 장애의 예방, 개선 또는 치료용 조성물 |
| WO2018167589A1 (en) | 2017-03-16 | 2018-09-20 | Inventia Healthcare Private Limited | Pharmaceutical composition comprising dapagliflozin |
| WO2019087239A1 (ja) * | 2017-10-30 | 2019-05-09 | 合同会社カルナヘルスサポート | 腎症治療剤 |
| WO2019092770A1 (ja) * | 2017-11-07 | 2019-05-16 | 合同会社カルナヘルスサポート | 網膜疾患治療剤 |
| AU2018444285A1 (en) * | 2018-10-01 | 2021-05-20 | Astrazeneca Ab | Compositions for reducing serum uric acid |
| BR112021010708A2 (pt) | 2018-12-06 | 2021-08-24 | Arthrosi Therapeutics, Inc. | Formas cristalinas de um composto para tratar ou prevenir gota ou hiperuricemia |
| AU2019392750B2 (en) | 2018-12-06 | 2025-07-10 | Arthrosi Therapeutics, Inc. | Methods for treating or preventing gout or hyperuricemia |
| WO2020178821A1 (en) * | 2019-03-03 | 2020-09-10 | Algatechnologies Ltd. | Compositions comprising algae powder and uses thereof |
| JP6831961B2 (ja) * | 2019-10-23 | 2021-02-24 | 株式会社カルナヘルスサポート | 網膜疾患治療剤 |
| US11759474B2 (en) | 2019-11-28 | 2023-09-19 | Boehringer Ingelheim Vetmedica Gmbh | Use of SGLT-2 inhibitors in the drying-off of non-human mammals |
| EP4164624A4 (en) * | 2020-06-10 | 2024-10-16 | Arthrosi Therapeutics, Inc. | METHODS OF TREATMENT OR PREVENTION OF CHRONIC KIDNEY DISEASE |
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| JP3065235B2 (ja) | 1995-11-07 | 2000-07-17 | 田辺製薬株式会社 | プロピオフェノン誘導体およびその製法 |
| JP3006513B2 (ja) | 1995-11-07 | 2000-02-07 | 田辺製薬株式会社 | 医薬組成物 |
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| JPH10245391A (ja) | 1997-03-03 | 1998-09-14 | Dainippon Ink & Chem Inc | ７−グリコシロキシベンゾピラン誘導体を有効成分とする糖尿病治療剤 |
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| CA2672001A1 (en) | 2001-04-27 | 2002-11-07 | Ajinomoto Co., Inc. | N-substituted pyrazole-o-glycoside derivatives and therapeutic agent for diabetes containing the same |
| ATE369787T1 (de) | 2001-06-20 | 2007-09-15 | Purdue Research Foundation | Druckmanschette mit körperbeleuchtung zur verwendung bei der optischen nichtinvasiven messung von blutparametern |
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| BRPI0408140B8 (pt) | 2003-03-14 | 2018-12-11 | Astellas Pharma Inc | derivado de c-glicosídeo ou seu sal, composição farmacêutica e uso do derivado de c-glicosídeo ou seu sal |
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| TW200606129A (en) | 2004-07-26 | 2006-02-16 | Chugai Pharmaceutical Co Ltd | Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same |
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| TW200637839A (en) | 2005-01-07 | 2006-11-01 | Taisho Pharmaceutical Co Ltd | 1-thio-d-glucitol derivatives |
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| TWI448291B (zh) * | 2006-11-09 | 2014-08-11 | Boehringer Ingelheim Int | 使用ｓｇｌｔ-２抑制劑之組合療法及彼等之醫藥組合物 |
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-
2009
- 2009-05-15 BR BRPI0913129A patent/BRPI0913129A2/pt not_active IP Right Cessation
- 2009-05-15 CA CA2725047A patent/CA2725047A1/en not_active Abandoned
- 2009-05-15 MX MX2010012656A patent/MX2010012656A/es active IP Right Grant
- 2009-05-15 US US12/993,750 patent/US8791077B2/en not_active Expired - Fee Related
- 2009-05-15 WO PCT/US2009/044156 patent/WO2009143020A1/en not_active Ceased
- 2009-05-15 CN CN200980128978.3A patent/CN102105153B/zh not_active Expired - Fee Related
- 2009-05-15 JP JP2011510594A patent/JP5820269B2/ja not_active Expired - Fee Related
- 2009-05-15 ES ES09751249.5T patent/ES2526930T3/es active Active
- 2009-05-15 EP EP13181659.7A patent/EP2668953A1/en not_active Withdrawn
- 2009-05-15 EP EP09751249.5A patent/EP2291189B1/en not_active Not-in-force
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2014
- 2014-06-23 JP JP2014128550A patent/JP2014205700A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2291189A1 (en) | 2011-03-09 |
| CN102105153B (zh) | 2014-03-05 |
| JP2011520965A (ja) | 2011-07-21 |
| MX2010012656A (es) | 2010-12-20 |
| WO2009143020A1 (en) | 2009-11-26 |
| US8791077B2 (en) | 2014-07-29 |
| BRPI0913129A2 (pt) | 2016-01-05 |
| CA2725047A1 (en) | 2009-11-26 |
| EP2291189B1 (en) | 2014-10-01 |
| US20110065658A1 (en) | 2011-03-17 |
| JP5820269B2 (ja) | 2015-11-24 |
| CN102105153A (zh) | 2011-06-22 |
| JP2014205700A (ja) | 2014-10-30 |
| EP2668953A1 (en) | 2013-12-04 |
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