CN101973944B - 一种Gefitinib Form 1 晶型的制备方法 - Google Patents
一种Gefitinib Form 1 晶型的制备方法 Download PDFInfo
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- CN101973944B CN101973944B CN 201010515608 CN201010515608A CN101973944B CN 101973944 B CN101973944 B CN 101973944B CN 201010515608 CN201010515608 CN 201010515608 CN 201010515608 A CN201010515608 A CN 201010515608A CN 101973944 B CN101973944 B CN 101973944B
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- 0 COc1cc2ncnc(Nc(cc3Cl)ccc3F)c2cc1OCCCN1CC*CC1 Chemical compound COc1cc2ncnc(Nc(cc3Cl)ccc3F)c2cc1OCCCN1CC*CC1 0.000 description 1
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CN 201010515608 CN101973944B (zh) | 2010-10-14 | 2010-10-14 | 一种Gefitinib Form 1 晶型的制备方法 |
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CN 201010515608 CN101973944B (zh) | 2010-10-14 | 2010-10-14 | 一种Gefitinib Form 1 晶型的制备方法 |
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CN101973944A CN101973944A (zh) | 2011-02-16 |
CN101973944B true CN101973944B (zh) | 2012-07-04 |
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CN 201010515608 Active CN101973944B (zh) | 2010-10-14 | 2010-10-14 | 一种Gefitinib Form 1 晶型的制备方法 |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103896862B (zh) * | 2012-12-25 | 2017-05-10 | 江苏天士力帝益药业有限公司 | 一种吉非替尼Form 1晶型的制备方法 |
CN103910690A (zh) * | 2013-01-06 | 2014-07-09 | 上海科胜药物研发有限公司 | 一种吉非替尼新晶型及其制备方法 |
CN103102316A (zh) * | 2013-01-17 | 2013-05-15 | 李彦 | ZD1839Form 1晶型的制备方法 |
KR20150001936A (ko) * | 2013-06-28 | 2015-01-07 | 제일약품주식회사 | 게피티닙의 신규한 결정형 및 이의 제조방법 |
CN104016930B (zh) * | 2014-06-03 | 2015-11-11 | 广东药学院 | 一种吉非替尼的精制方法 |
CN104277005A (zh) * | 2014-09-19 | 2015-01-14 | 成都新恒创药业有限公司 | 一种吉非替尼Form 1晶型的制备方法 |
JP6871255B2 (ja) | 2015-12-30 | 2021-05-12 | シントン・ベスローテン・フェンノートシャップ | ゲフィチニブの結晶形aを製造する方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1652790A (zh) * | 2002-02-26 | 2005-08-10 | 阿斯特拉曾尼卡有限公司 | 新型晶形抗癌化合物zd1839 |
WO2006090413A1 (en) * | 2005-02-23 | 2006-08-31 | Natco Pharma Limited | Novel crystalline form of gefitinib and a process for its preparation |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1652790A (zh) * | 2002-02-26 | 2005-08-10 | 阿斯特拉曾尼卡有限公司 | 新型晶形抗癌化合物zd1839 |
WO2006090413A1 (en) * | 2005-02-23 | 2006-08-31 | Natco Pharma Limited | Novel crystalline form of gefitinib and a process for its preparation |
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CN101973944A (zh) | 2011-02-16 |
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Effective date of registration: 20150624 Address after: 210042 Xuanwu Avenue, Jiangsu, Nanjing, No. 699 -18 Patentee after: Jiangsu Simcere Pharmaceutical Research Company Limited Patentee after: Jiangsu Simcere Pharmaceutical Co., Ltd. Address before: 210042 Xuanwu Avenue, Jiangsu, Nanjing, No. 699 -18 Patentee before: Jiangsu Simcere Pharmaceutical Research Company Limited |
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Effective date of registration: 20160728 Address after: 210042 Xuanwu District, Xuanwu District, Jiangsu, Nanjing No. 699 -18 Patentee after: Jiangsu Simcere Pharmaceutical Co., Ltd. Address before: 210042 Xuanwu Avenue, Jiangsu, Nanjing, No. 699 -18 Patentee before: Jiangsu Simcere Pharmaceutical Research Company Limited Patentee before: Jiangsu Simcere Pharmaceutical Co., Ltd. |
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