CN101809024A - 吡铂的口服制剂 - Google Patents

吡铂的口服制剂 Download PDF

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Publication number
CN101809024A
CN101809024A CN200880103323A CN200880103323A CN101809024A CN 101809024 A CN101809024 A CN 101809024A CN 200880103323 A CN200880103323 A CN 200880103323A CN 200880103323 A CN200880103323 A CN 200880103323A CN 101809024 A CN101809024 A CN 101809024A
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CN
China
Prior art keywords
preparation
cancer
picoplatin
pyrrole
pyrrole platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880103323A
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English (en)
Chinese (zh)
Inventor
A·X·陈
C·郭
C·A·普罗西夏伊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poniard Pharmaceuticals Inc
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Poniard Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poniard Pharmaceuticals Inc filed Critical Poniard Pharmaceuticals Inc
Publication of CN101809024A publication Critical patent/CN101809024A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200880103323A 2007-07-16 2008-07-16 吡铂的口服制剂 Pending CN101809024A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95003307P 2007-07-16 2007-07-16
US60/950,033 2007-07-16
US4396208P 2008-04-10 2008-04-10
US61/043,962 2008-04-10
PCT/US2008/008669 WO2009011861A1 (en) 2007-07-16 2008-07-16 Oral formulations for picoplatin

Publications (1)

Publication Number Publication Date
CN101809024A true CN101809024A (zh) 2010-08-18

Family

ID=40259929

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880103323A Pending CN101809024A (zh) 2007-07-16 2008-07-16 吡铂的口服制剂

Country Status (7)

Country Link
US (1) US20100310661A1 (enExample)
EP (1) EP2178893A4 (enExample)
JP (1) JP2010533714A (enExample)
CN (1) CN101809024A (enExample)
CA (1) CA2693057A1 (enExample)
TW (1) TW200920347A (enExample)
WO (1) WO2009011861A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108136030A (zh) * 2015-07-30 2018-06-08 大化制药株式会社 含有高浓度紫杉烷的用于口服给药的药物组合物
CN119699569A (zh) * 2024-12-23 2025-03-28 晨光生物科技集团股份有限公司 一种叶黄素酯油悬液及其制备方法与应用

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US8168661B2 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
KR20090109130A (ko) * 2007-02-09 2009-10-19 포니아드 파마슈티칼즈, 인크. 캡슐화된 피코플라틴
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
EP2249827A4 (en) * 2008-02-08 2012-05-30 Poniard Pharmaceuticals Inc USE OF PICOPLATIN AND CETUXIMAB IN THE TREATMENT OF COLORECTAL CANCER
WO2010120336A1 (en) * 2009-04-15 2010-10-21 Poniard Pharmaceuticals, Inc. High bioavailability oral picoplatin anti-cancer therapy
WO2011034394A2 (ko) * 2009-09-21 2011-03-24 주식회사 중외제약 옥살리플라틴의 나노 입자 및 이를 제조하는 방법
EA031793B1 (ru) * 2010-06-02 2019-02-28 Астеллас Дойчланд Гмбх Пероральные лекарственные формы бендамустина
CN101926757B (zh) 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
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KR101612257B1 (ko) 2015-07-30 2016-04-20 대화제약 주식회사 고농도의 탁산을 포함하는 경구 투여용 약학 조성물
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PL247245B1 (pl) * 2019-01-31 2025-06-02 Gdanski Univ Medyczny Samoemulgująca kompozycja farmaceutyczna w postaci ciekłej zawierająca jako substancję aktywną substancję leczniczą nietrwałą w środowisku wodnym
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108136030A (zh) * 2015-07-30 2018-06-08 大化制药株式会社 含有高浓度紫杉烷的用于口服给药的药物组合物
CN108136030B (zh) * 2015-07-30 2021-01-26 大化制药株式会社 含有高浓度紫杉烷的用于口服给药的药物组合物
CN119699569A (zh) * 2024-12-23 2025-03-28 晨光生物科技集团股份有限公司 一种叶黄素酯油悬液及其制备方法与应用
CN119699569B (zh) * 2024-12-23 2025-10-17 晨光生物科技集团股份有限公司 一种叶黄素酯油悬液及其制备方法与应用

Also Published As

Publication number Publication date
TW200920347A (en) 2009-05-16
US20100310661A1 (en) 2010-12-09
EP2178893A4 (en) 2012-09-19
JP2010533714A (ja) 2010-10-28
WO2009011861A1 (en) 2009-01-22
CA2693057A1 (en) 2009-01-22
EP2178893A1 (en) 2010-04-28

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