BRPI0313191A2 - composição e processo para produzir um agregado de platina e formulação farmacêutica - Google Patents
composição e processo para produzir um agregado de platina e formulação farmacêuticaInfo
- Publication number
- BRPI0313191A2 BRPI0313191A2 BRPI0313191A BR0313191A BRPI0313191A2 BR PI0313191 A2 BRPI0313191 A2 BR PI0313191A2 BR PI0313191 A BRPI0313191 A BR PI0313191A BR 0313191 A BR0313191 A BR 0313191A BR PI0313191 A2 BRPI0313191 A2 BR PI0313191A2
- Authority
- BR
- Brazil
- Prior art keywords
- producing
- composition
- pharmaceutical formulation
- aggregate
- platinum
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40087502P | 2002-08-02 | 2002-08-02 | |
PCT/US2003/024350 WO2004054499A2 (en) | 2002-08-02 | 2003-08-04 | Platinum aggregates and process for producing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0313191A2 true BRPI0313191A2 (pt) | 2016-11-08 |
Family
ID=32595039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0313191A BRPI0313191A2 (pt) | 2002-08-02 | 2003-08-04 | composição e processo para produzir um agregado de platina e formulação farmacêutica |
Country Status (13)
Country | Link |
---|---|
US (1) | US20040101553A1 (pt) |
EP (1) | EP1545459A4 (pt) |
JP (1) | JP2006502233A (pt) |
KR (1) | KR20050038011A (pt) |
CN (1) | CN1681478A (pt) |
AU (1) | AU2003302314A1 (pt) |
BR (1) | BRPI0313191A2 (pt) |
CA (1) | CA2494673A1 (pt) |
IL (1) | IL166654A0 (pt) |
MX (1) | MXPA05001312A (pt) |
NZ (1) | NZ538179A (pt) |
WO (1) | WO2004054499A2 (pt) |
ZA (1) | ZA200501176B (pt) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0011903D0 (en) * | 2000-05-18 | 2000-07-05 | Astrazeneca Ab | Combination chemotherapy |
CA2456746A1 (en) * | 2001-08-20 | 2003-02-27 | Transave, Inc. | Method for treating lung cancers |
US9186322B2 (en) | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
DK1581236T3 (da) * | 2002-10-29 | 2013-12-02 | Insmed Inc | Opretholdt afgivelse af antiinfektionsmidler |
US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
US20070065522A1 (en) * | 2004-03-18 | 2007-03-22 | Transave, Inc. | Administration of high potency platinum compound formulations by inhalation |
WO2005089448A2 (en) * | 2004-03-18 | 2005-09-29 | Transave, Inc. | Administration of cisplatin by inhalation |
WO2005112957A1 (en) * | 2004-05-21 | 2005-12-01 | Transave, Inc. | Treatment of lung diseases and pre-lung disease conditions |
JP5735724B2 (ja) * | 2004-11-08 | 2015-06-17 | インスメッド, インコーポレイテッド | 腹腔内投与される脂質ベースの白金化合物製剤を用いた、癌の治療方法 |
WO2007056264A2 (en) * | 2005-11-08 | 2007-05-18 | Transave, Inc. | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
WO2007056236A2 (en) * | 2005-11-08 | 2007-05-18 | Transave, Inc. | Methods of treating cancer with lipid-based platinum compound formulations administered intravenously |
US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
US20070122350A1 (en) * | 2005-11-30 | 2007-05-31 | Transave, Inc. | Safe and effective methods of administering therapeutic agents |
EP1962805B1 (en) | 2005-12-08 | 2016-07-06 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections |
GR20060100144A (el) * | 2006-03-03 | 2007-10-17 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene | |
US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8178564B2 (en) | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
JP5364381B2 (ja) * | 2006-12-08 | 2013-12-11 | 片山化学工業株式会社 | アンミン白金錯体を高濃度で内包するリポソームおよびその製造方法 |
EP2114418A4 (en) * | 2007-02-09 | 2013-01-09 | Poniard Pharmaceuticals Inc | ORAL DOSAGE FORM WITH STABILIZED PICOPLATIN |
KR20150125728A (ko) * | 2007-02-09 | 2015-11-09 | 포니아드 파마슈티칼즈, 인크. | 캡슐화된 피코플라틴 |
US20100196455A1 (en) * | 2007-05-04 | 2010-08-05 | Transave, Inc. | Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof |
US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
JP2010533714A (ja) * | 2007-07-16 | 2010-10-28 | ポニアード ファーマシューティカルズ, インコーポレイテッド | ピコプラチンのための経口製剤 |
CN102014624A (zh) * | 2008-02-08 | 2011-04-13 | 帕纳德制药公司 | 治疗肺癌的吡铂和氨柔比星 |
JPWO2009148169A1 (ja) * | 2008-06-06 | 2011-11-04 | 片山化学工業株式会社 | アンミン白金錯体を高濃度に内包するリポソームを用いた腫瘍治療技術 |
RU2538199C2 (ru) * | 2009-02-04 | 2015-01-10 | Дзе Бригхэм Энд Вимен'З Хоспитэл, Инк. | Наносоединения платины и способы их применения |
US9566234B2 (en) | 2012-05-21 | 2017-02-14 | Insmed Incorporated | Systems for treating pulmonary infections |
JP2015530387A (ja) | 2012-09-04 | 2015-10-15 | エライゾン ファーマシューティカルズ, エルエルシー | 脂質複合体化シスプラチンによる肺癌の再発防止 |
WO2014052634A1 (en) * | 2012-09-27 | 2014-04-03 | The University Of North Carolina At Chapel Hill | Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof |
CA2891487A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
PT3142643T (pt) | 2014-05-15 | 2019-10-28 | Insmed Inc | Métodos para o tratamento de infeções mico bacterianas pulmonares não tuberculares |
CN106955271A (zh) * | 2016-01-08 | 2017-07-18 | 佛山英特医药科技有限公司 | 奥沙利铂聚集体及其制备方法 |
CN107260674A (zh) * | 2016-04-06 | 2017-10-20 | 广州英特基因科技有限公司 | 卡铂聚集体及其制备方法 |
CN107303276A (zh) * | 2016-04-22 | 2017-10-31 | 广州英特基因科技有限公司 | 多西他赛脂质体复合物及其制备方法 |
CN107303275A (zh) * | 2016-04-22 | 2017-10-31 | 广州英特基因科技有限公司 | 吉非替尼脂质体复合物及其制备方法 |
WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
WO2021183588A1 (en) * | 2020-03-10 | 2021-09-16 | Chung Yuan Christian University | Liposome composition and preparation method thereof |
Family Cites Families (51)
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US4451447A (en) * | 1980-03-31 | 1984-05-29 | Bristol-Myers Company | Pharmaceutical formulations |
US4981692A (en) * | 1983-03-24 | 1991-01-01 | The Liposome Company, Inc. | Therapeutic treatment by intramammary infusion |
USRE33071E (en) * | 1983-03-28 | 1989-09-26 | Platinum bound to transferrin for use in the treatment of breast tumors | |
US4590001A (en) * | 1983-03-28 | 1986-05-20 | Stjernholm Rune L | Platinum bound to transferrin for use in the treatment of breast tumors |
US5019369A (en) * | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
JPH0665648B2 (ja) * | 1985-09-25 | 1994-08-24 | 塩野義製薬株式会社 | 白金系抗癌物質の安定な凍結真空乾燥製剤 |
US5117022A (en) * | 1985-10-18 | 1992-05-26 | The Board Of Regents, The University Of Texas System | Hydrophobic cis-platinum complexes efficiently incorporated into liposomes |
US5041581A (en) * | 1985-10-18 | 1991-08-20 | The University Of Texas System Board Of Regents | Hydrophobic cis-platinum complexes efficiently incorporated into liposomes |
US5049388A (en) * | 1986-11-06 | 1991-09-17 | Research Development Foundation | Small particle aerosol liposome and liposome-drug combinations for medical use |
US5320906A (en) * | 1986-12-15 | 1994-06-14 | Vestar, Inc. | Delivery vehicles with amphiphile-associated active ingredient |
MX9203808A (es) * | 1987-03-05 | 1992-07-01 | Liposome Co Inc | Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos. |
US5616334A (en) * | 1987-03-05 | 1997-04-01 | The Liposome Company, Inc. | Low toxicity drug-lipid systems |
CA1338702C (en) * | 1987-03-05 | 1996-11-12 | Lawrence D. Mayer | High drug:lipid formulations of liposomal- antineoplastic agents |
IL83380A (en) * | 1987-07-30 | 1991-04-15 | Teva Pharma | Stable aqueous cisplatin solutions |
DE68901733T2 (de) * | 1988-03-04 | 1993-03-25 | Takeda Chemical Industries Ltd | Liposom-zusammensetzung. |
US5141751A (en) * | 1988-06-29 | 1992-08-25 | Daiichi Pharmaceutical Co., Ltd. | Lipid membrane structures |
US5549910A (en) * | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5858784A (en) * | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
US5756353A (en) * | 1991-12-17 | 1998-05-26 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol-and liposome-based delivery |
EP0551169A1 (en) * | 1992-01-10 | 1993-07-14 | Takeda Chemical Industries, Ltd. | Liposome composition and production thereof |
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US5780054A (en) * | 1996-01-17 | 1998-07-14 | University Of British Columbia | Methods for increasing the circulation half-life of protein-based therapeutics |
WO1997030696A1 (fr) * | 1996-02-26 | 1997-08-28 | Daiichi Pharmaceutical Co., Ltd. | Liposome et dispersion de liposome |
PT910382E (pt) * | 1996-04-26 | 2003-10-31 | Genaera Corp | Esqualamina em combinacao com outros agentes anti-cancro para o tratamento de tumores |
ATE252372T1 (de) * | 1996-08-23 | 2003-11-15 | Sequus Pharm Inc | Liposome enthaltend cisplatin |
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AU7711096A (en) * | 1996-12-03 | 1998-06-29 | Rijsuniversiteit Utrecht | Cisplatinum comprising pharmaceutical |
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US6090407A (en) * | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
US6787132B1 (en) * | 1997-12-04 | 2004-09-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Combined chemo-immunotherapy with liposomal drugs and cytokines |
US6726925B1 (en) * | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
CA2248592A1 (en) * | 1998-08-31 | 2000-02-29 | Christopher D. Batich | Microspheres for use in the treatment of cancer |
US20050074499A1 (en) * | 1999-03-17 | 2005-04-07 | Mitsubishi Chemical Corporation | Ligand-bonded complex |
US6723338B1 (en) * | 1999-04-01 | 2004-04-20 | Inex Pharmaceuticals Corporation | Compositions and methods for treating lymphoma |
US6852334B1 (en) * | 1999-04-20 | 2005-02-08 | The University Of British Columbia | Cationic peg-lipids and methods of use |
WO2000074634A2 (en) * | 1999-06-03 | 2000-12-14 | Au Jessie L S | Methods and compositions for modulating cell proliferation and cell death |
US6352996B1 (en) * | 1999-08-03 | 2002-03-05 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
CA2393233A1 (en) * | 1999-12-04 | 2001-06-07 | Research Development Foundation | Carbon dioxide enhancement of inhalation therapy |
WO2001056548A2 (en) * | 2000-02-04 | 2001-08-09 | Lipoxen Technologies Limited | Liposomes composition produced by a dehydration-rehydration process |
JP2004501955A (ja) * | 2000-06-30 | 2004-01-22 | アイネックス ファーマシューティカルズ コーポレイション | リポソーム抗新生物薬剤およびその使用 |
CA2437555A1 (en) * | 2001-02-01 | 2002-08-08 | Yiyu Zou | Stabilised polymeric aerosols for pulmonary gene delivery |
DE60210441T2 (de) * | 2001-04-23 | 2006-11-16 | Nucryst Pharmaceuticals Corp., Fort Saskatchewan | Arzneimittel oder pflaster enthaltend ein metall wie silber, gold, platin oder palladium als antimikrobiellen wirkstoff und dessen verwendung in der behandlung von hautentzündungen |
ES2261735T3 (es) * | 2001-05-18 | 2006-11-16 | Chiron Corporation | Sistema para la administracion de una formulacion de tobramicina. |
US7063860B2 (en) * | 2001-08-13 | 2006-06-20 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
CA2456746A1 (en) * | 2001-08-20 | 2003-02-27 | Transave, Inc. | Method for treating lung cancers |
EP1424898A4 (en) * | 2001-08-20 | 2008-04-02 | Transave Inc | TREATMENT OF CANCER BY INHALATION OF STABLE FORMULATIONS CONTAINING PLATINUM |
-
2003
- 2003-08-04 BR BRPI0313191A patent/BRPI0313191A2/pt not_active IP Right Cessation
- 2003-08-04 EP EP03810869A patent/EP1545459A4/en not_active Withdrawn
- 2003-08-04 US US10/634,144 patent/US20040101553A1/en not_active Abandoned
- 2003-08-04 NZ NZ538179A patent/NZ538179A/xx unknown
- 2003-08-04 CA CA002494673A patent/CA2494673A1/en not_active Abandoned
- 2003-08-04 MX MXPA05001312A patent/MXPA05001312A/es unknown
- 2003-08-04 KR KR1020057001943A patent/KR20050038011A/ko not_active Application Discontinuation
- 2003-08-04 JP JP2004560279A patent/JP2006502233A/ja active Pending
- 2003-08-04 AU AU2003302314A patent/AU2003302314A1/en not_active Abandoned
- 2003-08-04 CN CNA038219891A patent/CN1681478A/zh active Pending
- 2003-08-04 WO PCT/US2003/024350 patent/WO2004054499A2/en active Application Filing
-
2005
- 2005-02-02 IL IL16665405A patent/IL166654A0/xx unknown
- 2005-02-09 ZA ZA200501176A patent/ZA200501176B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2004054499A3 (en) | 2004-12-02 |
CA2494673A1 (en) | 2004-07-01 |
IL166654A0 (en) | 2006-01-15 |
ZA200501176B (en) | 2006-09-27 |
JP2006502233A (ja) | 2006-01-19 |
EP1545459A2 (en) | 2005-06-29 |
AU2003302314A1 (en) | 2004-07-09 |
EP1545459A4 (en) | 2007-08-22 |
US20040101553A1 (en) | 2004-05-27 |
WO2004054499A2 (en) | 2004-07-01 |
NZ538179A (en) | 2008-09-26 |
MXPA05001312A (es) | 2005-08-03 |
KR20050038011A (ko) | 2005-04-25 |
CN1681478A (zh) | 2005-10-12 |
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B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] |
Free format text: ANULADA A EXIGENCIA CODIGO 6.7 PUBLICADA NA RPI NO 1889 DE 20/03/2007, POR TER SIDO INDEVIDA. |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |