CA2693057A1 - Oral formulations for picoplatin - Google Patents
Oral formulations for picoplatin Download PDFInfo
- Publication number
- CA2693057A1 CA2693057A1 CA 2693057 CA2693057A CA2693057A1 CA 2693057 A1 CA2693057 A1 CA 2693057A1 CA 2693057 CA2693057 CA 2693057 CA 2693057 A CA2693057 A CA 2693057A CA 2693057 A1 CA2693057 A1 CA 2693057A1
- Authority
- CA
- Canada
- Prior art keywords
- picoplatin
- formulation
- cancer
- oil
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229950005566 picoplatin Drugs 0.000 title claims abstract description 399
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- 239000000203 mixture Substances 0.000 title claims abstract description 200
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- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims description 13
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Organic Chemistry (AREA)
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- Oncology (AREA)
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95003307P | 2007-07-16 | 2007-07-16 | |
| US60/950,033 | 2007-07-16 | ||
| US4396208P | 2008-04-10 | 2008-04-10 | |
| US61/043,962 | 2008-04-10 | ||
| PCT/US2008/008669 WO2009011861A1 (en) | 2007-07-16 | 2008-07-16 | Oral formulations for picoplatin |
Publications (1)
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| US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| MX2009008487A (es) * | 2007-02-09 | 2010-01-15 | Poniard Pharmaceuticals Inc | Picoplatino encapsulado. |
| TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
| US20110053879A1 (en) * | 2008-02-08 | 2011-03-03 | Poniard Pharmaceuticals, Inc. | Picoplatin and amrubicin to treat lung cancer |
| EP2418955A4 (en) * | 2009-04-15 | 2012-11-21 | Poniard Pharmaceuticals Inc | ORBIOTIC ANTICANCER THERAPY BASED ON HIGH BIODISIBILITY PICOPLATIN |
| AU2010296180B2 (en) * | 2009-09-21 | 2016-05-05 | Bio-Synectics, Inc | Oxaliplatin nanoparticles and method for preparing same |
| WO2011151087A1 (en) * | 2010-06-02 | 2011-12-08 | Astellas Deutschland Gmbh | Oral dosage forms of bendamustine |
| CN101926757B (zh) * | 2010-09-01 | 2013-01-02 | 北京大学 | 一种难溶性药物的液体组合物及其制备方法 |
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| AU2013257546B2 (en) | 2012-05-10 | 2017-12-14 | Painreform Ltd. | Depot formulations of a local anesthetic and methods for preparation thereof |
| KR101612257B1 (ko) * | 2015-07-30 | 2016-04-20 | 대화제약 주식회사 | 고농도의 탁산을 포함하는 경구 투여용 약학 조성물 |
| KR101612260B1 (ko) | 2015-07-30 | 2016-04-20 | 대화제약 주식회사 | 고농도의 탁산을 포함하는 경구 투여용 약학 조성물 |
| ES2895948T3 (es) | 2015-07-30 | 2022-02-23 | Dae Hwa Pharma Co Ltd | Composición farmacéutica para administración oral que comprende taxano a alta concentración |
| GB2541387A (en) * | 2015-08-14 | 2017-02-22 | Res Center Pharmaceutical Eng Gmbh | Self-emulsifying Nanosuspensions as Drug Delivery Systems (SENDDS) |
| WO2017096530A1 (zh) * | 2015-12-08 | 2017-06-15 | 广州中科蓝华生物科技有限公司 | 癸氧喹酯固体分散体、其制备方法和用途 |
| CN110636863A (zh) * | 2017-05-18 | 2019-12-31 | 丘比株式会社 | 具有自乳化性的组合物及其制造方法及纳米乳液及其制造方法 |
| CN108066771A (zh) * | 2017-12-15 | 2018-05-25 | 北京思如诺科技有限公司 | 一种具有高载药量环境响应型抗肿瘤纳米药物、载体以及制备方法 |
| PL247245B1 (pl) * | 2019-01-31 | 2025-06-02 | Gdanski Univ Medyczny | Samoemulgująca kompozycja farmaceutyczna w postaci ciekłej zawierająca jako substancję aktywną substancję leczniczą nietrwałą w środowisku wodnym |
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| CN119699569B (zh) * | 2024-12-23 | 2025-10-17 | 晨光生物科技集团股份有限公司 | 一种叶黄素酯油悬液及其制备方法与应用 |
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-
2008
- 2008-07-16 CN CN200880103323A patent/CN101809024A/zh active Pending
- 2008-07-16 TW TW097127053A patent/TW200920347A/zh unknown
- 2008-07-16 CA CA 2693057 patent/CA2693057A1/en not_active Abandoned
- 2008-07-16 JP JP2010517010A patent/JP2010533714A/ja not_active Withdrawn
- 2008-07-16 US US12/669,274 patent/US20100310661A1/en not_active Abandoned
- 2008-07-16 WO PCT/US2008/008669 patent/WO2009011861A1/en not_active Ceased
- 2008-07-16 EP EP08780206A patent/EP2178893A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009011861A1 (en) | 2009-01-22 |
| EP2178893A1 (en) | 2010-04-28 |
| JP2010533714A (ja) | 2010-10-28 |
| CN101809024A (zh) | 2010-08-18 |
| TW200920347A (en) | 2009-05-16 |
| US20100310661A1 (en) | 2010-12-09 |
| EP2178893A4 (en) | 2012-09-19 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20140716 |