TW200920347A

TW200920347A - Oral formulations for picoplatin

Oral formulations for picoplatin Download PDF

Info

Publication number: TW200920347A
Authority: TW; Taiwan
Prior art keywords: cancer; picoplatin; preparation; formulation; oil
Prior art date: 2007-07-16

Application number

TW097127053A

Other languages

English (en)

Chinese (zh)

Inventor

Andrew Xian Chen

Cheni Kwok

Christopher A Procyshyn

Original Assignee

Poniard Pharmaceuticals Inc

Priority date

2007-07-16

Filing date

2008-07-16

Publication date

2009-05-16

2008-07-16 Application filed by Poniard Pharmaceuticals Inc filed Critical Poniard Pharmaceuticals Inc

2009-05-16 Publication of TW200920347A publication Critical patent/TW200920347A/zh

Links

IIMIOEBMYPRQGU-UHFFFAOYSA-L picoplatin Chemical compound N.[Cl-].[Cl-].[Pt+2].CC1=CC=CC=N1 IIMIOEBMYPRQGU-UHFFFAOYSA-L 0.000 title claims abstract description 192
229950005566 picoplatin Drugs 0.000 title claims abstract description 189
239000000203 mixture Substances 0.000 title claims abstract description 140
238000009472 formulation Methods 0.000 title claims abstract description 91
238000002360 preparation method Methods 0.000 claims abstract description 86
238000000034 method Methods 0.000 claims abstract description 74
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 63
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239000002245 particle Substances 0.000 claims description 79
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235000019198 oils Nutrition 0.000 claims description 61
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 60
239000002904 solvent Substances 0.000 claims description 54
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229910052697 platinum Inorganic materials 0.000 claims description 31
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