CN101616925B - 三环化合物及其作为糖皮质激素受体调节剂的用途 - Google Patents
三环化合物及其作为糖皮质激素受体调节剂的用途 Download PDFInfo
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- CN101616925B CN101616925B CN2008800052954A CN200880005295A CN101616925B CN 101616925 B CN101616925 B CN 101616925B CN 2008800052954 A CN2008800052954 A CN 2008800052954A CN 200880005295 A CN200880005295 A CN 200880005295A CN 101616925 B CN101616925 B CN 101616925B
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- ZITUOTORLGBDOZ-STDXNEQLSA-N Cc1ncccc1NC(c1ccc(C(Cc2ccccc2)(CC2)C(CC3)C[C@]2(CCC(F)(F)F)O)c3c1)=O Chemical compound Cc1ncccc1NC(c1ccc(C(Cc2ccccc2)(CC2)C(CC3)C[C@]2(CCC(F)(F)F)O)c3c1)=O ZITUOTORLGBDOZ-STDXNEQLSA-N 0.000 description 1
- 0 O[C@](CC1)CC(C[C@]2O)[C@]1(CCc1ccccc1)c(cc1)c2cc1C1=Nc2cccnc2*1 Chemical compound O[C@](CC1)CC(C[C@]2O)[C@]1(CCc1ccccc1)c(cc1)c2cc1C1=Nc2cccnc2*1 0.000 description 1
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88798107P | 2007-02-02 | 2007-02-02 | |
| US60/887,981 | 2007-02-02 | ||
| PCT/IB2008/000229 WO2008093227A1 (en) | 2007-02-02 | 2008-01-25 | Tricyclic compounds and their use as glucocorticoid receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101616925A CN101616925A (zh) | 2009-12-30 |
| CN101616925B true CN101616925B (zh) | 2012-05-23 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008800052954A Expired - Fee Related CN101616925B (zh) | 2007-02-02 | 2008-01-25 | 三环化合物及其作为糖皮质激素受体调节剂的用途 |
| CN2008800056527A Expired - Fee Related CN101616896B (zh) | 2007-02-02 | 2008-01-28 | 三环类化合物及其作为糖皮质激素受体调节剂的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008800056527A Expired - Fee Related CN101616896B (zh) | 2007-02-02 | 2008-01-28 | 三环类化合物及其作为糖皮质激素受体调节剂的用途 |
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| US6001876A (en) | 1996-07-24 | 1999-12-14 | Warner-Lambert Company | Isobutylgaba and its derivatives for the treatment of pain |
| DK2114970T3 (da) | 2007-02-02 | 2011-09-19 | Pfizer Prod Inc | Tricykliske forbindelser og deres anvendelse som glucocorticoidreceptormodulatorer |
| PE20110559A1 (es) * | 2008-07-28 | 2011-08-06 | Pfizer | (4bR,6R,7R,8aS)-4b-BENCIL-6,7-DIHIDROXI-6-METIL-N-(2-METILPIRIDIN-3-IL)-10-OXO-7-FENIL-4b,5,6,7,8,8a,9,10-OCTAHIDROFENANTRENO-2-CARBOXAMIDA COMO MODULADOR DEL RECEPTOR GLUCOCORTICOIDE |
| WO2010059894A1 (en) * | 2008-11-21 | 2010-05-27 | Bridge Pharma, Inc. | Ocular formulations of norketotifen |
| US20100137246A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
| US20100135983A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
| US20100136094A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
| US20100137787A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Delivery devices for modulating inflammation |
| US20100136096A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
| US20100136097A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
| US20100136095A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
| WO2011141909A2 (en) | 2010-05-10 | 2011-11-17 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
| CA2806900A1 (en) * | 2010-08-27 | 2012-03-01 | Corcept Therapeutics, Inc. | Pyridyl-amine fused azadecalin modulators |
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