UA94639C2 - Трициклические соединения и их применение как модуляторов глюкокортикоидного рецептора - Google Patents
Трициклические соединения и их применение как модуляторов глюкокортикоидного рецептораInfo
- Publication number
- UA94639C2 UA94639C2 UAA200907728A UAA200907728A UA94639C2 UA 94639 C2 UA94639 C2 UA 94639C2 UA A200907728 A UAA200907728 A UA A200907728A UA A200907728 A UAA200907728 A UA A200907728A UA 94639 C2 UA94639 C2 UA 94639C2
- Authority
- UA
- Ukraine
- Prior art keywords
- glucocorticoid receptor
- receptor modulators
- tricyclic compounds
- compounds
- modulators
- Prior art date
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract
Изобретение касается соединений формулы I или их солей, которые являются модуляторами рецептора глюкокортикоида. Соединения и соли изобретения могут быть использованы в лечении состояний, опосредованных активностью рецептора глюкокортикоида.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US88798107P | 2007-02-02 | 2007-02-02 |
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Publication Number | Publication Date |
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UA94639C2 true UA94639C2 (ru) | 2011-05-25 |
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UAA200907728A UA94639C2 (ru) | 2007-02-02 | 2008-01-25 | Трициклические соединения и их применение как модуляторов глюкокортикоидного рецептора |
UAA200907730A UA95332C2 (ru) | 2007-02-02 | 2008-01-28 | Трехциклические соединения и их применение в качестве модуляторов глюкокортикоидного рецептора |
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UAA200907730A UA95332C2 (ru) | 2007-02-02 | 2008-01-28 | Трехциклические соединения и их применение в качестве модуляторов глюкокортикоидного рецептора |
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CN101616925B (zh) | 2007-02-02 | 2012-05-23 | 辉瑞产品公司 | 三环化合物及其作为糖皮质激素受体调节剂的用途 |
PT2307375E (pt) * | 2008-07-28 | 2015-01-14 | Pfizer | Compostos da fenantrenona, composições e métodos |
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US20100136096A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136094A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136095A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136097A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100135983A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100137844A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Delivery devices for modulating inflammation |
US20100137246A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
CA2798697A1 (en) | 2010-05-10 | 2011-11-17 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
SG187909A1 (en) * | 2010-08-27 | 2013-03-28 | Corcept Therapeutics Inc | Pyridyl-amine fused azadecalin modulators |
MX2013010576A (es) * | 2011-03-15 | 2014-03-12 | Abbvie Inc | Moduladores de receptores de hormonas nucleares. |
US8545904B1 (en) | 2012-06-05 | 2013-10-01 | Liquid Innovators, LLC | Topical composition containing Carapa (andiroba) oil for psoriasis and other related dermatological disorders |
US9227901B2 (en) * | 2012-07-05 | 2016-01-05 | Abbvie Inc. | Process for preparing bicyclic amine derivatives |
TW201422590A (zh) | 2012-09-07 | 2014-06-16 | Abbvie Inc | 雜環核激素受體調節劑 |
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