CU23848B1 - Derivados de octahidrofenantreno n(2-metilpiridino-3-il) carboxamida útiles como moduladores de receptor de glucocorticoides - Google Patents
Derivados de octahidrofenantreno n(2-metilpiridino-3-il) carboxamida útiles como moduladores de receptor de glucocorticoidesInfo
- Publication number
- CU23848B1 CU23848B1 CU2009000132A CU20090132A CU23848B1 CU 23848 B1 CU23848 B1 CU 23848B1 CU 2009000132 A CU2009000132 A CU 2009000132A CU 20090132 A CU20090132 A CU 20090132A CU 23848 B1 CU23848 B1 CU 23848B1
- Authority
- CU
- Cuba
- Prior art keywords
- octahydrophenantrene
- methylpyridino
- receptor modulators
- glucocorticoid receptor
- carboxamide derivatives
- Prior art date
Links
- 229940117965 Glucocorticoid receptor modulator Drugs 0.000 title 1
- 229940053202 antiepileptics carboxamide derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C07—ORGANIC CHEMISTRY
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- Psychology (AREA)
- Biochemistry (AREA)
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Abstract
La presente invención está dirigida a compuestos de f'rmula I: ESPACIO PARA LA FÓRMULA en la que R1 es –P(O)(OH)2; o una sal del mismo.
Applications Claiming Priority (2)
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US88798107P | 2007-02-02 | 2007-02-02 | |
PCT/IB2008/000229 WO2008093227A1 (en) | 2007-02-02 | 2008-01-25 | Tricyclic compounds and their use as glucocorticoid receptor modulators |
Publications (2)
Publication Number | Publication Date |
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CU20090132A7 CU20090132A7 (es) | 2011-10-14 |
CU23848B1 true CU23848B1 (es) | 2012-10-15 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CU20090133A CU20090133A7 (es) | 2007-02-02 | 2009-07-24 | Compuestos tricíclicos y sus composiciones |
CU2009000132A CU23848B1 (es) | 2007-02-02 | 2009-07-24 | Derivados de octahidrofenantreno n(2-metilpiridino-3-il) carboxamida útiles como moduladores de receptor de glucocorticoides |
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CU20090133A CU20090133A7 (es) | 2007-02-02 | 2009-07-24 | Compuestos tricíclicos y sus composiciones |
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WO2008093227A1 (en) * | 2007-02-02 | 2008-08-07 | Pfizer Products Inc. | Tricyclic compounds and their use as glucocorticoid receptor modulators |
MX2011001053A (es) * | 2008-07-28 | 2011-04-21 | Pfizer | Compuestos de fenantrenona, composiciones y metodos. |
US8765787B2 (en) * | 2008-11-21 | 2014-07-01 | Bridge Pharma, Inc. | Methods of treatment of xerophthalmia with self-preserving ocular formulations of norketotifen |
US20100136095A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100137843A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Delivery devices for modulating inflammation |
US20100135983A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100136097A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136096A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100136094A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100137246A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
EP2569307A2 (en) | 2010-05-10 | 2013-03-20 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
WO2012027702A1 (en) * | 2010-08-27 | 2012-03-01 | Corcept Therapeutics, Inc. | Pyridyl-amine fused azadecalin modulators |
AU2012229952A1 (en) * | 2011-03-15 | 2013-04-18 | Abbvie Inc. | Nuclear hormone receptor modulators |
US8545904B1 (en) | 2012-06-05 | 2013-10-01 | Liquid Innovators, LLC | Topical composition containing Carapa (andiroba) oil for psoriasis and other related dermatological disorders |
US9227901B2 (en) * | 2012-07-05 | 2016-01-05 | Abbvie Inc. | Process for preparing bicyclic amine derivatives |
TW201422590A (zh) | 2012-09-07 | 2014-06-16 | Abbvie Inc | 雜環核激素受體調節劑 |
WO2014094357A1 (en) | 2012-12-21 | 2014-06-26 | Abbvie Inc. | Heterocyclic nuclear hormone receptor modulators |
DK3142637T3 (da) | 2014-05-16 | 2020-08-24 | Olaplex Inc | Keratin treatment formulations and methods |
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