PE20090113A1 - Compuestos triciclicos como moduladores del receptor de glucocorticoides, composiciones y procedimientos - Google Patents

Compuestos triciclicos como moduladores del receptor de glucocorticoides, composiciones y procedimientos

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Publication number
PE20090113A1
PE20090113A1 PE2008000234A PE2008000234A PE20090113A1 PE 20090113 A1 PE20090113 A1 PE 20090113A1 PE 2008000234 A PE2008000234 A PE 2008000234A PE 2008000234 A PE2008000234 A PE 2008000234A PE 20090113 A1 PE20090113 A1 PE 20090113A1
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PE
Peru
Prior art keywords
modulators
glucocorticoid receptor
procedures
compositions
tricyclic compounds
Prior art date
Application number
PE2008000234A
Other languages
English (en)
Inventor
Rajesh Venkateswaran Devraj
Crescenzo Gary A De
Xiao Hu
Kevin De Wayne Jerome
Mark Gerald Obukowicz
Paul Vincent Rucker
Ronald Keith Webber
Lisa Olson
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PE20090113A1 publication Critical patent/PE20090113A1/es

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Abstract

REFERIDA A UN COMPUESTO TRICICLICO DE FORMULA (I), DONDE R1 ES -P(O)(OH)2. ES UN COMPUESTO PREFERIDO DIHIDROGENOFOSFATO DE (2R,4ALFAS,10ALFAR)-4ALFA-BENCIL-7-((2-METILPIRIDIN-3-IL)CARBAMAOIL)-2-(TRIFLUOROMETIL)-1,2,3,4,4ALFA,9,10,10ALFA-OCTAHIDROFENANTREN-2-ILO O UNA SAL DEL MISMO, ENTRE OTROS. TAMBIEN ESTA REFERIDA A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON MODULADORES DEL RECEPTOR DE GLUCOCORTICOIDES Y SON UTILES EN EL TRATAMIENTO DE TRASTORNOS ENDOCRINOS, REUMATICOS, AFECCIONES DERMATOLOGICAS, ENTRE OTROS
PE2008000234A 2007-02-02 2008-02-01 Compuestos triciclicos como moduladores del receptor de glucocorticoides, composiciones y procedimientos PE20090113A1 (es)

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US88798107P 2007-02-02 2007-02-02

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PE20090113A1 true PE20090113A1 (es) 2009-02-13

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PE2008000231A PE20081736A1 (es) 2007-02-02 2008-01-31 Compuestos triciclicos, composiciones, y procedimientos
PE2008000234A PE20090113A1 (es) 2007-02-02 2008-02-01 Compuestos triciclicos como moduladores del receptor de glucocorticoides, composiciones y procedimientos

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CN101616925B (zh) 2007-02-02 2012-05-23 辉瑞产品公司 三环化合物及其作为糖皮质激素受体调节剂的用途
PT2307375E (pt) * 2008-07-28 2015-01-14 Pfizer Compostos da fenantrenona, composições e métodos
WO2010059894A1 (en) * 2008-11-21 2010-05-27 Bridge Pharma, Inc. Ocular formulations of norketotifen
US20100136096A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for modulating inflammation
US20100136094A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for modulating inflammation
US20100136095A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for modulating inflammation
US20100136097A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for modulating inflammation
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