PT3209295T - Métodos de tratamento das condições oculares - Google Patents

Métodos de tratamento das condições oculares

Info

Publication number
PT3209295T
PT3209295T PT158523407T PT15852340T PT3209295T PT 3209295 T PT3209295 T PT 3209295T PT 158523407 T PT158523407 T PT 158523407T PT 15852340 T PT15852340 T PT 15852340T PT 3209295 T PT3209295 T PT 3209295T
Authority
PT
Portugal
Prior art keywords
methods
treating ocular
ocular conditions
conditions
treating
Prior art date
Application number
PT158523407T
Other languages
English (en)
Original Assignee
Oyster Point Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55748136&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3209295(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oyster Point Pharma Inc filed Critical Oyster Point Pharma Inc
Publication of PT3209295T publication Critical patent/PT3209295T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emergency Medicine (AREA)
PT158523407T 2014-10-20 2015-10-19 Métodos de tratamento das condições oculares PT3209295T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462066280P 2014-10-20 2014-10-20
US201562100844P 2015-01-07 2015-01-07

Publications (1)

Publication Number Publication Date
PT3209295T true PT3209295T (pt) 2021-02-05

Family

ID=55748136

Family Applications (2)

Application Number Title Priority Date Filing Date
PT158523407T PT3209295T (pt) 2014-10-20 2015-10-19 Métodos de tratamento das condições oculares
PT202125563T PT3848028T (pt) 2014-10-20 2015-10-19 Métodos de tratamento de estados oculares

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT202125563T PT3848028T (pt) 2014-10-20 2015-10-19 Métodos de tratamento de estados oculares

Country Status (20)

Country Link
US (11) US9597284B2 (pt)
EP (3) EP3209295B2 (pt)
JP (3) JP6873906B2 (pt)
KR (2) KR102601505B1 (pt)
CN (3) CN111956650B (pt)
AU (2) AU2015336216B2 (pt)
BR (2) BR112017008097B1 (pt)
CA (1) CA2965129C (pt)
DK (2) DK3848028T3 (pt)
EA (1) EA035335B1 (pt)
ES (1) ES2848977T5 (pt)
FI (1) FI3848028T3 (pt)
IL (2) IL251769B (pt)
MX (2) MX2017005064A (pt)
MY (1) MY186870A (pt)
PH (1) PH12017500602A1 (pt)
PT (2) PT3209295T (pt)
SG (2) SG10202011669PA (pt)
WO (1) WO2016064759A1 (pt)
ZA (1) ZA201703467B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9597284B2 (en) 2014-10-20 2017-03-21 Oyster Point Pharma, Inc. Dry eye treatments
EP3439661B1 (en) 2016-04-07 2021-08-04 Oyster Point Pharma, Inc. Methods of treating ocular conditions
WO2020014232A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions
WO2020014217A1 (en) * 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Methods of treating ocular conditions
WO2021222230A1 (en) 2020-04-28 2021-11-04 Oyster Point Pharma, Inc. Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277855B1 (en) * 2000-04-21 2001-08-21 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with nicotinic acetylcholine receptor agonists
US20030008892A1 (en) 2001-07-09 2003-01-09 Pfizer Inc. Pharmaceutical composition and method of modulating cholinergic function in a mammal
AU2002341327A1 (en) 2001-11-29 2003-06-10 Pfizer Products Inc. Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof
WO2004039366A1 (en) 2002-11-01 2004-05-13 Pharmacia & Upjohn Company Llc Nicotinic acetylcholine agonists in the treatment of glaucoma and retinal neuropathy
US20060270592A1 (en) * 2004-03-19 2006-11-30 Ophthalmic Research Associates, Inc. Use of neurotransmitters and neuropeptides for the treatment of dry eye diseases and related conditions
EP1802276A1 (en) 2004-10-15 2007-07-04 Pfizer Products Inc. Compositions and methods for intranasal, buccal, sublingual and pulmonary delivery of varenicline
EP1929996B1 (en) * 2004-11-09 2011-02-16 Novagali Pharma S.A. Ophthalmic emulsions containing an immunosuppressive agent
AU2006226509A1 (en) * 2005-03-22 2006-09-28 Niconovum Ab Use of an artificial sweetener to enhance absorption of nicotine
US20110086086A1 (en) 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
CA2620202C (en) 2005-08-26 2016-10-04 The Board Of Trustees Of The Leland Stanford Junior University Therapy procedure for drug delivery for trigeminal pain
US8153162B2 (en) 2005-09-27 2012-04-10 Tissuetech, Inc. Purified amniotic membrane compositions and methods of use
TWI454262B (zh) 2006-11-02 2014-10-01 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
US20080132475A1 (en) * 2006-12-05 2008-06-05 Charles Gerald Connor Treatment for dry eye
RS51970B (en) * 2007-02-02 2012-02-29 Pfizer Products Inc. TRICYCLIC UNITS AND THEIR USE AS MODULATORS OF GLUCOCORTICOID RECEPTORS
US20090093446A1 (en) 2007-10-05 2009-04-09 Winston Laboratories, Inc. Method for alleviating keratoconjunctivitis sicca
CL2008003507A1 (es) * 2007-11-26 2009-11-27 Neuroderm Ltd Composicion farmaceutica que comprende nicotina y un inhibidor de la desensibilizacion del receptor de acetilcolina nicotinico (nachr) opipramol; kit farmaceutico; dispositivo medico; y uso para tratar una enfermedad o trastorno del sistema nervioso central o periferico.
US20090215787A1 (en) 2008-02-22 2009-08-27 Mai De Ltd. Preparations of new polymorphic forms of varenicline tartrate
CN101959888A (zh) 2008-03-05 2011-01-26 塔加西普特公司 二氮杂双环烷烃的烟碱乙酰胆碱受体亚型的选择性酰胺
WO2010028011A1 (en) 2008-09-05 2010-03-11 Targacept, Inc. Amides of diazabicyclononanes and uses thereof
US20110263629A1 (en) * 2008-09-05 2011-10-27 Targacept, Inc. Amides of diazabicyclooctanes and uses thereof
US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
WO2010065443A1 (en) 2008-12-01 2010-06-10 Targacept, Inc. Synthesis and novel salt forms of (r)-5-((e)-2-(pyrrolidin-3-ylvinyl)pyrimidine
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US8821457B2 (en) * 2010-09-08 2014-09-02 Johnson & Johnson Vision Care, Inc. Punctal plug containing drug formulation
US20140170157A1 (en) * 2011-06-15 2014-06-19 Glaxosmithkline Intellectual Property (No.2) Limited Method of selecting therapeutic indications
RU2014103098A (ru) * 2011-06-30 2015-08-10 Торэй Индастриз, Инк. Противозудный агент
JO3766B1 (ar) * 2011-10-20 2021-01-31 Novartis Ag منشط مستقبل أسيتيل كولين الفا - 7 النيكوتيني
CN104094114A (zh) * 2011-11-30 2014-10-08 黛尔格诺斯蒂尔有限公司 干眼诊断
ES2426517B1 (es) * 2012-04-20 2014-05-14 Genetracer Biotech S.L Método para predecir la seguridad de un tratamiento farmacológico
MX2015013186A (es) 2013-03-15 2016-04-15 Glia Llc Adminitracion craneal de productos farmaceuticos.
NZ704579A (en) 2013-04-19 2018-10-26 Oculeve Inc Nasal stimulation devices and methods
US9597284B2 (en) 2014-10-20 2017-03-21 Oyster Point Pharma, Inc. Dry eye treatments
EP3439661B1 (en) 2016-04-07 2021-08-04 Oyster Point Pharma, Inc. Methods of treating ocular conditions
WO2020014232A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions
WO2020014217A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Methods of treating ocular conditions

Also Published As

Publication number Publication date
DK3209295T4 (da) 2024-02-26
CN111956650B (zh) 2024-06-04
US20200246336A1 (en) 2020-08-06
AU2020213351B2 (en) 2023-04-06
CN111956803A (zh) 2020-11-20
US20160106745A1 (en) 2016-04-21
US20160106665A1 (en) 2016-04-21
US20170239244A1 (en) 2017-08-24
FI3848028T3 (fi) 2024-08-21
CA2965129A1 (en) 2016-04-28
MX2017005064A (es) 2018-02-23
DK3848028T3 (da) 2024-08-26
CN111956650A (zh) 2020-11-20
SG11201703135XA (en) 2017-05-30
IL251769A0 (en) 2017-06-29
EA035335B1 (ru) 2020-05-28
BR112017008097B1 (pt) 2023-03-28
JP2021038250A (ja) 2021-03-11
KR102511955B1 (ko) 2023-03-22
MY186870A (en) 2021-08-26
US11903941B2 (en) 2024-02-20
KR20230042144A (ko) 2023-03-27
AU2020213351A1 (en) 2020-08-27
EP3848028B1 (en) 2024-05-29
BR112017008097A2 (pt) 2018-02-20
PT3848028T (pt) 2024-09-20
US10456396B2 (en) 2019-10-29
US20160106744A1 (en) 2016-04-21
US20240173318A1 (en) 2024-05-30
JP2023024574A (ja) 2023-02-16
EP3209295A1 (en) 2017-08-30
US9504645B2 (en) 2016-11-29
US11224598B2 (en) 2022-01-18
US20230226054A1 (en) 2023-07-20
US11911380B2 (en) 2024-02-27
EP4413974A3 (en) 2024-10-09
AU2015336216A1 (en) 2017-06-08
EP3848028A1 (en) 2021-07-14
JP7502404B2 (ja) 2024-06-18
US20160106746A1 (en) 2016-04-21
US20220233528A1 (en) 2022-07-28
JP2017531044A (ja) 2017-10-19
US9532944B2 (en) 2017-01-03
MX2022005888A (es) 2022-06-14
EA201790893A1 (ru) 2018-01-31
EP3848028B9 (en) 2024-10-16
US20230226053A1 (en) 2023-07-20
EP4413974A2 (en) 2024-08-14
EP3209295A4 (en) 2018-05-23
KR20170086040A (ko) 2017-07-25
US9597284B2 (en) 2017-03-21
EP3209295B1 (en) 2020-12-09
IL293188A (en) 2022-07-01
DK3209295T3 (da) 2021-03-01
AU2015336216B2 (en) 2020-05-21
JP6873906B2 (ja) 2021-05-19
ZA201703467B (en) 2023-12-20
ES2848977T3 (es) 2021-08-13
EP3209295B2 (en) 2023-12-06
PH12017500602A1 (en) 2017-09-04
BR122022025737B1 (pt) 2023-12-26
SG10202011669PA (en) 2020-12-30
IL251769B (en) 2022-06-01
CN107106542B (zh) 2020-05-08
WO2016064759A1 (en) 2016-04-28
KR102601505B1 (ko) 2023-11-14
CA2965129C (en) 2024-03-12
US11903943B2 (en) 2024-02-20
JP7257371B2 (ja) 2023-04-13
CN107106542A (zh) 2017-08-29
US11903942B2 (en) 2024-02-20
US20230226052A1 (en) 2023-07-20
ES2848977T5 (es) 2024-06-06
US9504644B2 (en) 2016-11-29

Similar Documents

Publication Publication Date Title
IL283561B (en) Methods for treating eye diseases
HK1246179A1 (zh) 治療視網膜疾病的方法
GB201701673D0 (en) Methods of well treatment
IL257252A (en) Methods for treating fgf21-related disorders
IL246791A0 (en) Compositions and methods for treating eye diseases
HK1248552A1 (zh) 使用川地匹坦的治療方法
ZA201700416B (en) Methods for treating or preventing ophthalmological conditions
IL290069A (en) Methods for treating eye conditions
GB201410116D0 (en) Method of treatment
IL253028B (en) treatment method
GB201416832D0 (en) Methods of treatment
IL251769A0 (en) Methods for treating eye conditions
HK1249866A1 (zh) 用他塞利昔布進行治療的方法
HK1244692A1 (zh) 治療纖維化的方法
HK1243937A1 (zh) 治療疾病的方法
GB201412010D0 (en) Treatment of hypertransaminasemia
GB201512139D0 (en) Methods of treatment
GB201421980D0 (en) Method of treatment
GB201421982D0 (en) Method of treatment
GB201415331D0 (en) Method of treatment
GB201414780D0 (en) Method Of Treatment
GB201511017D0 (en) Method of treatment
AU2014905194A0 (en) Method of Treatment
AU2014904907A0 (en) Method of Treatment
AU2014904371A0 (en) Method of treatment