SG11201703135XA - Methods of treating ocular conditions - Google Patents

Methods of treating ocular conditions

Info

Publication number
SG11201703135XA
SG11201703135XA SG11201703135XA SG11201703135XA SG11201703135XA SG 11201703135X A SG11201703135X A SG 11201703135XA SG 11201703135X A SG11201703135X A SG 11201703135XA SG 11201703135X A SG11201703135X A SG 11201703135XA SG 11201703135X A SG11201703135X A SG 11201703135XA
Authority
SG
Singapore
Prior art keywords
methods
treating ocular
ocular conditions
conditions
treating
Prior art date
Application number
SG11201703135XA
Inventor
Douglas Michael Ackermann Jr
James Loudin
Kenneth J Mandell
Original Assignee
Oyster Point Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55748136&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201703135X(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oyster Point Pharma Inc filed Critical Oyster Point Pharma Inc
Publication of SG11201703135XA publication Critical patent/SG11201703135XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995Pyrazines or piperazines forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
SG11201703135XA 2014-10-20 2015-10-19 Methods of treating ocular conditions SG11201703135XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462066280P 2014-10-20 2014-10-20
US201562100844P 2015-01-07 2015-01-07
PCT/US2015/056273 WO2016064759A1 (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions

Publications (1)

Publication Number Publication Date
SG11201703135XA true SG11201703135XA (en) 2017-05-30

Family

ID=55748136

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202011669PA SG10202011669PA (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions
SG11201703135XA SG11201703135XA (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10202011669PA SG10202011669PA (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions

Country Status (19)

Country Link
US (10) US9532944B2 (en)
EP (2) EP3209295B2 (en)
JP (3) JP6873906B2 (en)
KR (2) KR102601505B1 (en)
CN (3) CN107106542B (en)
AU (2) AU2015336216B2 (en)
BR (2) BR122022025737B1 (en)
CA (1) CA2965129C (en)
DK (1) DK3209295T4 (en)
EA (1) EA035335B1 (en)
ES (1) ES2848977T3 (en)
IL (2) IL251769B (en)
MX (2) MX2017005064A (en)
MY (1) MY186870A (en)
PH (1) PH12017500602A1 (en)
PT (1) PT3209295T (en)
SG (2) SG10202011669PA (en)
WO (1) WO2016064759A1 (en)
ZA (1) ZA201703467B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9532944B2 (en) 2014-10-20 2017-01-03 Oyster Point Pharma, Inc. Methods of improving ocular discomfort
JP7090551B2 (en) * 2016-04-07 2022-06-24 オイスター ポイント ファーマ インコーポレイテッド How to treat eye conditions
WO2020014232A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions
TW202019424A (en) * 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 Methods of treating ocular conditions
TW202206078A (en) 2020-04-28 2022-02-16 美商奧伊斯特普安生物製藥公司 Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections

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US6277855B1 (en) 2000-04-21 2001-08-21 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with nicotinic acetylcholine receptor agonists
US20030008892A1 (en) 2001-07-09 2003-01-09 Pfizer Inc. Pharmaceutical composition and method of modulating cholinergic function in a mammal
CA2468705A1 (en) 2001-11-29 2003-06-05 Pfizer Products Inc. Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof
AU2003269413A1 (en) * 2002-11-01 2004-05-25 Pharmacia & Upjohn Company Llc Nicotinic acetylcholine agonists in the treatment of glaucoma and retinal neuropathy
US20060270592A1 (en) * 2004-03-19 2006-11-30 Ophthalmic Research Associates, Inc. Use of neurotransmitters and neuropeptides for the treatment of dry eye diseases and related conditions
MX2007004495A (en) 2004-10-15 2007-05-10 Pfizer Prod Inc Compositions and methods for intranasal, buccal, sublingual and pulmonary delivery of varenicline.
CA2586074C (en) * 2004-11-09 2013-07-23 Novagali Pharma Sa Ophthalmic oil-in-water type emulsion with stable positive zeta potential
WO2006100075A2 (en) * 2005-03-22 2006-09-28 Niconovum Ab Use of an artificial sweetener to enhance absorption of nicotine
US20110086086A1 (en) 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
JP5276982B2 (en) 2005-08-26 2013-08-28 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ Method for the treatment of headache by administration of oxytocin
US8182841B2 (en) 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-inflammation methods
TWI404532B (en) 2006-11-02 2013-08-11 Targacept Inc Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes
DK2114970T3 (en) * 2007-02-02 2011-09-19 Pfizer Prod Inc Tricyclic compounds and their use as glucocorticoid receptor modulators
US20090093446A1 (en) 2007-10-05 2009-04-09 Winston Laboratories, Inc. Method for alleviating keratoconjunctivitis sicca
CL2008003507A1 (en) * 2007-11-26 2009-11-27 Neuroderm Ltd Pharmaceutical composition comprising nicotine and a nicotinic acetylcholine receptor (nachr) opipramol desensitization inhibitor; pharmaceutical kit; medical device; and use to treat a disease or disorder of the central or peripheral nervous system.
US20090215787A1 (en) 2008-02-22 2009-08-27 Mai De Ltd. Preparations of new polymorphic forms of varenicline tartrate
RU2010140613A (en) 2008-03-05 2012-04-10 Таргасепт, Инк. (Us) AMIDES OF DIAZABicycloalkanes Selective for the Subtype of Nicotinic Acetylcholine Receptors
JP2012502039A (en) * 2008-09-05 2012-01-26 ターガセプト,インコーポレイテッド Diazabicyclooctane amides and uses thereof
WO2010028011A1 (en) 2008-09-05 2010-03-11 Targacept, Inc. Amides of diazabicyclononanes and uses thereof
PT3279195T (en) 2008-12-01 2020-09-29 Oyster Point Pharma Inc Synthesis and novel salt forms of (r)-5-((e)-2-(pyrrolidin-3-ylvinyl)pyrimidine
US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
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JP6162705B2 (en) * 2011-10-20 2017-07-12 ノバルティス アーゲー Biomarkers predicting responsiveness to treatment with alpha 7 nicotinic acetylcholine receptor activators
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TW202019424A (en) 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 Methods of treating ocular conditions
WO2020014232A1 (en) 2018-07-10 2020-01-16 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions

Also Published As

Publication number Publication date
CN111956650A (en) 2020-11-20
US20160106745A1 (en) 2016-04-21
BR122022025737B1 (en) 2023-12-26
CN107106542A (en) 2017-08-29
EP3848028A1 (en) 2021-07-14
EP3209295B1 (en) 2020-12-09
WO2016064759A1 (en) 2016-04-28
US11903943B2 (en) 2024-02-20
JP2021038250A (en) 2021-03-11
JP7257371B2 (en) 2023-04-13
KR102601505B1 (en) 2023-11-14
IL251769B (en) 2022-06-01
SG10202011669PA (en) 2020-12-30
IL293188A (en) 2022-07-01
KR102511955B1 (en) 2023-03-22
AU2015336216A1 (en) 2017-06-08
US20230226052A1 (en) 2023-07-20
US9504644B2 (en) 2016-11-29
US11903941B2 (en) 2024-02-20
US11224598B2 (en) 2022-01-18
AU2020213351B2 (en) 2023-04-06
US20170239244A1 (en) 2017-08-24
EA201790893A1 (en) 2018-01-31
CN111956803A (en) 2020-11-20
ES2848977T3 (en) 2021-08-13
MY186870A (en) 2021-08-26
EA035335B1 (en) 2020-05-28
CN107106542B (en) 2020-05-08
CA2965129A1 (en) 2016-04-28
KR20230042144A (en) 2023-03-27
DK3209295T4 (en) 2024-02-26
US20160106665A1 (en) 2016-04-21
US10456396B2 (en) 2019-10-29
PH12017500602A1 (en) 2017-09-04
AU2020213351A1 (en) 2020-08-27
US20160106746A1 (en) 2016-04-21
US20220233528A1 (en) 2022-07-28
MX2022005888A (en) 2022-06-14
US20230226054A1 (en) 2023-07-20
EP3209295B2 (en) 2023-12-06
JP2023024574A (en) 2023-02-16
DK3209295T3 (en) 2021-03-01
US20200246336A1 (en) 2020-08-06
PT3209295T (en) 2021-02-05
EP3209295A4 (en) 2018-05-23
BR112017008097A2 (en) 2018-02-20
JP6873906B2 (en) 2021-05-19
AU2015336216B2 (en) 2020-05-21
US20230226053A1 (en) 2023-07-20
CA2965129C (en) 2024-03-12
IL251769A0 (en) 2017-06-29
US20160106744A1 (en) 2016-04-21
ZA201703467B (en) 2023-12-20
US9504645B2 (en) 2016-11-29
JP2017531044A (en) 2017-10-19
EP3209295A1 (en) 2017-08-30
US11911380B2 (en) 2024-02-27
KR20170086040A (en) 2017-07-25
BR112017008097B1 (en) 2023-03-28
MX2017005064A (en) 2018-02-23
US9597284B2 (en) 2017-03-21
US9532944B2 (en) 2017-01-03
US11903942B2 (en) 2024-02-20

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