CN101522618A - 3-氮杂-双环[3.1.0]己烷衍生物 - Google Patents

3-氮杂-双环[3.1.0]己烷衍生物 Download PDF

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Publication number
CN101522618A
CN101522618A CNA2007800357375A CN200780035737A CN101522618A CN 101522618 A CN101522618 A CN 101522618A CN A2007800357375 A CNA2007800357375 A CN A2007800357375A CN 200780035737 A CN200780035737 A CN 200780035737A CN 101522618 A CN101522618 A CN 101522618A
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methyl
bicyclo
thiazole
hex
ylmethyl
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Chinese (zh)
Inventor
汗默德·艾萨维
克里斯托弗·博斯
马库斯·古德
拉尔夫·科贝尔施泰因
戴维·莱曼
蒂埃里·西弗朗
丹尼尔·特拉赫塞尔
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Actelion Pharmaceuticals Ltd
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Actelion Pharmaceuticals Ltd
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Publication of CN101522618A publication Critical patent/CN101522618A/zh
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Addiction (AREA)
  • Vascular Medicine (AREA)
CNA2007800357375A 2006-09-29 2007-09-28 3-氮杂-双环[3.1.0]己烷衍生物 Pending CN101522618A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006053570 2006-09-29
IBPCT/IB2006/053570 2006-09-29

Publications (1)

Publication Number Publication Date
CN101522618A true CN101522618A (zh) 2009-09-02

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CNA2007800357375A Pending CN101522618A (zh) 2006-09-29 2007-09-28 3-氮杂-双环[3.1.0]己烷衍生物

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Country Link
US (1) US20100016401A1 (https=)
EP (1) EP2079690B1 (https=)
JP (1) JP2010504957A (https=)
KR (1) KR20090077051A (https=)
CN (1) CN101522618A (https=)
AR (1) AR063081A1 (https=)
AT (1) ATE481383T1 (https=)
CA (1) CA2662612A1 (https=)
CL (1) CL2007002809A1 (https=)
DE (1) DE602007009284D1 (https=)
ES (1) ES2350460T3 (https=)
TW (1) TW200823227A (https=)
WO (1) WO2008038251A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103201261A (zh) * 2010-11-10 2013-07-10 埃科特莱茵药品有限公司 用作为食欲素受体拮抗剂的内酰胺衍生物
CN104718213A (zh) * 2012-07-18 2015-06-17 圣母大学 5,5-杂芳族抗感染化合物

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2669060A1 (en) 2006-12-01 2008-06-05 Actelion Pharmaceuticals Ltd Piperidine compounds
CL2007003827A1 (es) * 2006-12-28 2008-09-26 Actelion Pharmaceuticals Ltd Compuestos derivados de n-(2-aza-biciclo(3.1.0)hex-3-ilmetil)amida; y su uso para prevenir o tratar la depresion, neurosis, esquizofrenia, ansiedad, adicciones, epilepsia, dolor, enfermedades cardiacas, entre otras.
CL2008000836A1 (es) * 2007-03-26 2008-11-07 Actelion Pharmaceuticals Ltd Compuestos derivados de tiazolidina, antagonistas del receptor de orexina; composicion farmaceutica que los comprende; y su uso en el tratamiento de neurosis emocional, depresion grave, trastornos psicoticos, alzheimer, parkinson, dolor, entre otras.
WO2008150364A1 (en) * 2007-05-23 2008-12-11 Merck & Co., Inc. Cyclopropyl pyrrolidine orexin receptor antagonists
JP4881476B2 (ja) 2007-05-23 2012-02-22 メルク・シャープ・エンド・ドーム・コーポレイション ピリジルピペリジン・オレキシン受容体アンタゴニスト
ATE524466T1 (de) 2007-07-03 2011-09-15 Actelion Pharmaceuticals Ltd 3-azabicycloä3.3.0üoktanverbindungen
CA2693817A1 (en) * 2007-07-27 2009-02-05 Actelion Pharmaceuticals Ltd Trans-3-aza-bicyclo[3.1.0]hexane derivatives
KR20100046047A (ko) * 2007-07-27 2010-05-04 액테리온 파마슈티칼 리미티드 2-아자-비시클로[3.3.0]옥탄 유도체
AR067665A1 (es) 2007-07-27 2009-10-21 Actelion Pharmaceuticals Ltd Derivados de trans-3- aza-biciclo ( 3.1.0) hexano
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009040730A2 (en) * 2007-09-24 2009-04-02 Actelion Pharmaceuticals Ltd Pyrrolidines and piperidines as orexin receptor antagonists
MX2010008993A (es) * 2008-02-21 2010-09-07 Actelion Pharmaceuticals Ltd Derivados de 2-aza-biciclo-[2.2.1]heptano.
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