CN101062171A - Method for producing bacterial virus element medicine for preventing bacterial virus mixed infection for critter, fowl and aquatic animals - Google Patents
Method for producing bacterial virus element medicine for preventing bacterial virus mixed infection for critter, fowl and aquatic animals Download PDFInfo
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- CN101062171A CN101062171A CNA2007100280680A CN200710028068A CN101062171A CN 101062171 A CN101062171 A CN 101062171A CN A2007100280680 A CNA2007100280680 A CN A2007100280680A CN 200710028068 A CN200710028068 A CN 200710028068A CN 101062171 A CN101062171 A CN 101062171A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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Abstract
The invention relates to a process for preparing antiviral or antibiotic essence for the prevention and treatment of bacterial and virus mixed infectious diseases of livestock, fowl and aquatic animals, which consists of mixing Chinese herbs of Bupleurum root, rhubarb horsetails, Coptis chinensis, baikal skullcap root, Chinese angelica root, clerodendroa cyrtophyllum and cordate houttuynia, lixiviating with 80-90% alcoholic solution, charging one or more antiviral or antibiotic elements.
Description
[technical field]
The present invention relates to a kind of preparation method of Chinese-western medicine preparation, relate in particular to a kind of preparation method that is used to prevent and treat the bacterial disease toxin of domestic animal, poultry and aquatic animal bacterial virus mixed infection disease.
[background technology]
In recent years, the breed scale of China fowl poultry, aquatic products industry constantly enlarges, the degree of its intensification and batch production is more and more higher, but aspect (one) livestock rearing: (1), density too high (2), poultry, domestic animal are raised together with (3), sanitary condition is poor, thereby cause various bacterial virus mixed infection diseases to be propagated mutually between poultry, domestic animal and infection fast.(2) aspect aquaculture: (3) are raised together with in (1), density too high (2), various aquatic animal, the breed water pollution is serious day by day, thereby cause the frequent generation of various bacterial virus mixed infection diseases, are seriously perplexing the sound development of culture fishery.When poultry and aquatic animal occurred by various bacterial virus mixed infection disease in breeding process, people generally used Western medicine such as antiviral or antibiotics, antibiotics simply in a large number: florfenicol, polymyxin, gentamycin or pefloxacin etc.Though these medicines have certain curative effect effect, but spreading unchecked application, multiple medicine repeated use can cause liver and gall kidney burden, the bacterial virus of animal to produce drug resistance and may bring bad pathological changes, make and monophagia, particular about food or abnormal phenomena such as do not get fat in breeding process, occur, if do not prevent as early as possible and treat, can cause the death of poultry, aquatic animal when serious.By dried current poultry and aquatic animal paathogenic factor many kinds are arranged, wherein their immunocompetence reduces, have a delicate constitution, it is to cause poultry and the morbific principal element of aquatic animal that the resistance difference allows extraneous various bacterial viruses take advantage of a weak point, and is their healthy stealthy killer so immunocompetence is hanged down.Yet the health care veterinary medicine that can improve poultry and aquatic animal immunocompetence is fewer, current health care veterinary medicine on the market is just to play no scorching antibody effect under the anosis situation of poultry and aquatic animal, if poultry and aquatic animal have taken place by various bacteriovirus infections, current health care veterinary medicine all can not play health-care effect.
Along with being on the rise of poultry, the various bacterial virus diseases of aquaculture, utilize Chinese medicine conditioning to add the science and technology that western medicine combines and prevent and treat various diseases, be one of diseases prevention and treatment developing direction of poultry and aquatic animal from now on.By discovering:, and finally cause the appearance of various bacteria virus mixed infection disease in case the infection of another kind or various bacteria virus can be accelerated and increase the weight of to poultry or aquatic animal by certain bacteriovirus infection.Its reason is after poultry or aquatic animal are by certain bacteriovirus infection, to influence the intravital various digestion of animal, blood, immune system, reduce immunity, anti-virus ability etc., thereby, and reach the various bacteria virus mixed infection and become disease for other bacterial virus enters in the body or a large amount of in vivo breeding provides condition.Therefore earlier adopt multiple Chinese herbal medicine by approach such as soaking or oral, the digestive system and the blood system of conditioning poultry, aquatic animal, thereby reach the purpose that improves immunocompetence, resistance against diseases, stoping virus to penetrate the place by one or more antiviral or antibiotics, antibiotics Western medicine again becomes owner of arterial cell, influences virus uncoating, suppress virus multiplication, hinder the synthetic of viral nucleic acid, thereby reach the effect of treatment.Finally reach the sick prevention of bacterial virus mixed infection, the purpose of treatment.
[summary of the invention]
The present invention is directed to above deficiency, provide a kind of utilization Chinese medicine conditioning to add the western medicine principle of combining, can effectively prevent and treat the preparation method of the bacterial disease toxin of domestic animal, poultry and aquatic animal bacterial virus mixed infection disease.
For realizing purpose of the present invention, the preparation method that is used to prevent and treat the bacterial disease toxin of domestic animal, poultry and aquatic animal bacterial virus mixed infection disease may further comprise the steps:
(1) by mass ratio 15～20: respectively take by weighing and mix Radix Bupleuri, Radix Et Rhizoma Rhei, SHUANGHUANGLIAN, Radix Scutellariae, Radix Angelicae Sinensis, Folium Isatidis, Herba Houttuyniae at 10～20: 10～15: 5～10: 10～20: 12～20: 15～20;
(2) with 80～90% alcoholic solution lixiviates, after room temperature left standstill and treats layering, it was centrifugal, dry to get supernatant liquid;
(3) in gnotobasis with Chinese medicine ethanol extraction and one or more antiviral or antibiotics, antibiotics Western medicine powder with 3～5: 1 mass ratio mixes.
Among the present invention,
Radix Bupleuri, reducing fever by reconciliation cures mainly invasion of SHAO YANG by pathogen, alternate attack of chill and fever, cold, fever and malaria cold and heat; Dispersing the stagnated live-QI to relieve the stagnation of QI cures mainly stagnation of QI due to depression of the liver.
Radix Et Rhizoma Rhei have purge heat, effect such as removing pathogenic heat from blood and toxic substance from the body, removing blood stasis, modern pharmacological research shows, it has antibiotic, antiinflammatory, anti-infective effect, Radix Et Rhizoma Rhei has more sensitive effect to staphylococcus aureus, gonococcus, streptococcus, next is to diphtheria corynebacterium, anthrax bacillus, Bacillus typhi and dysentery bacterium, to some virus (influenza virus, hepatitis B virus, herpes simplex virus etc.) certain inhibitory action is also arranged, multiple inflammation there is antiinflammatory action, the oozing out of early stage inflammation, swelling and the granulation hyperplasia in later stage are all had the obvious suppression effect.
Radix Scutellariae has anti-microbial effect, wider antimicrobial spectrum is arranged, dysentery bacterium, diphtheria corynebacterium, bacillus pyocyaneus, staphylococcus, streptococcus, Diplococcus pneumoniae and meningococcus etc. all there is inhibitory action, even the staphylococcus aureus to antibiotics such as penicillin have developed immunity to drugs still belongs to sensitivity to Radix Scutellariae.
Radix Angelicae Sinensis can be protected hepatocyte, anti-inflammation, and blood fat reducing improves arteriosclerosis etc.
Folium Isatidis has the effect of heat-clearing and toxic substances removing, cooling blood for hemostasis, to influenza, pneumonia, dysentery, hepatitis, gastroenteritis, aphtha, carbuncle and the various hemorrhage person that belongs to the dominance of heat in the interior, therapeutical effect is preferably arranged all.
Herba Houttuyniae has antibacterial action, volatile oil components such as contained houttuynine sodium bisulfite, lauryl aldehyde, methyl n nonyl ketone, fragrant ethylene and quercitrin, cordarine in the Herba Houttuyniae, staphylococcus aureus, Staphylococcus albus, dysentery bacterium, bacillus pyocyaneus, Bacillus proteus, paracolon, Grain-positive bacillus cereus etc. all there are certain inhibitory action, stronger to staphylococcus aureus and Staphylococcus albus effect.Experiment shows that the bright juice of Herba Houttuyniae has remarkable inhibitory action to staphylococcus aureus; In addition, Herba Houttuyniae also has antivirus action.Herba Houttuyniae all has inhibitory action to multiple virus, and can delay the cytopathic effect of virus.
Bacterial disease toxin of the present invention all has good anti-effect to multiple malignant bacteria such as Aeromonas hydrophila, Edwardsiella, myxococcus, pseudomonas, vibrio etc., it not only has good opsonic action to systems such as the liver of domestic animal, poultry and aquatic animal, gallbladder, kidneys, and the disease that is caused by various pathogenic bacteria mixed infections is had the prevention and the treatment of significance.Under domestic animal, poultry and aquatic animal situation at healthy NIP, the bacterial disease toxin can improve their body immunity and resistance against diseases, and by facilitating digestion, improving appetite, increase feed intake, alleviate the toxic and side effects of other medicines, thereby the various bacteriovirus infection diseases and the health that effectively prevent domestic animal, poultry and aquatic animal increase fast.Be subjected to certain malignant bacteria or multiple malignant bacteria mixed infection when domestic animal, poultry and aquatic animal and have under the situation of inflammation, bacterial disease toxin of the present invention not only can heat clearing away, detoxifcation, sterilization, hemorrhagic disease, erythroderma, gill rot, black gill disease disease, enteritis disease, red leg disease and bacterial septicemia etc. that treatment is caused by bacteriovirus infection, and its quick restitution after can also reducing the toxic side effect of disease treatment process Chinese medicine and improving treatment, can obviously shorten treatment course of treatment of domestic animal, poultry and aquatic animal.The appearance of present technique has been filled up present domestic animal, poultry, aquatic animal to the prevention of bacterial virus mixed infection disease and the market vacancy effect of treatment double effects, and it has very high marketing using value.
The present invention is soluble in water, and steady quality.Can direct or mixed water and forage feed domestic animal, poultry and aquatic animal, their curative effect is all relatively good, and the drinking-water convenient drug administration, the absorbance height, widely distributed, drug residue free has no side effect, and safety range is wide.
[specific embodiment]
Embodiment 1:
(1) takes by weighing Radix Bupleuri 15 gram, Radix Et Rhizoma Rhei 10 grams, Radix Scutellariae 5 grams, Radix Angelicae Sinensis 10 grams, Folium Isatidis 12 grams, Herba Houttuyniae 15 grams, clean oven dry (degree of dehydration is 97%) back and add SHUANGHUANGLIAN sheet 10 grams and mix;
(2), after room temperature leaves standstill and treats layering, get centrifugal, the dry 50 gram Chinese medicine ethanol extractions that get of supernatant liquid with 100ml 86% alcoholic solution lixiviate;
(3) in gnotobasis, the Chinese medicine ethanol extraction is mixed and promptly gets the bacterial disease toxin with 10 gram florfenicols, 10 gram polymyxin.
This bacterial disease toxin is applicable to the sick mixed infection of colibacillosis, intestinal of chicken septic; Duck mixed type flower hepatopathy, hepatitis, pasteurellosis bacillus, oromeningitis, pneumonia, enteritis, diarrhoea cholera, intestinal toxicity syndrome; Aquatic animal mixed type bacterial infection gill rot, shelling, yellow gill disease, the swollen sick carapace appendage Peptic Ulcers of the gill, bacterial disease.
Embodiment 2:
(1) takes by weighing Radix Bupleuri 15 gram, Radix Et Rhizoma Rhei 10 grams, Radix Scutellariae 5 grams, Radix Angelicae Sinensis 10 grams, Folium Isatidis 12 grams, Herba Houttuyniae 15 grams, clean oven dry (degree of dehydration is 97%) back and add SHUANGHUANGLIAN sheet 10 grams and mix;
(2), after room temperature leaves standstill and treats layering, get centrifugal, the dry 50 gram Chinese medicine ethanol extractions that get of supernatant liquid with 100ml 86% alcoholic solution lixiviate Chinese medicinal powder;
(3) in gnotobasis, the Chinese medicine ethanol extraction is mixed and promptly gets the bacterial disease toxin with 10 gram rimantadines, 10 gram levofloxacin.
This bacterial disease toxin is applicable to that chicken virus, infectious bursa of Fabricius, flu, heating, eqpidemic disease, biography are propped up, pyretic toxicity disease, cleaning endotoxin; Duck mixed type virosis, influenza virus, heating, duck pestilence, flu, laryngitis, cough with asthma, viral oromeningitis; Pig circular ring virus 2 viral disease, influenza, asthma, pyretic toxicity disease infection; Aquatic animal muscle nebulousurine, caloric disease severe infection, bacterial disease viral disease, pyretic toxicity disease.
Embodiment 3:
(1) takes by weighing Radix Bupleuri 15 gram, Radix Et Rhizoma Rhei 10 grams, Radix Scutellariae 5 grams, Radix Angelicae Sinensis 10 grams, Folium Isatidis 12 grams, Herba Houttuyniae 15 grams, clean oven dry (degree of dehydration is 97%) back and add SHUANGHUANGLIAN sheet 10 grams and mix;
(2), after room temperature leaves standstill and treats layering, get centrifugal, the dry 50 gram Chinese medicine ethanol extractions that get of supernatant liquid with 100ml 86% alcoholic solution lixiviate Chinese medicinal powder;
(3) in gnotobasis, the Chinese medicine ethanol extraction is mixed and promptly gets the bacterial disease toxin with 10 gram taimulins, 10 gram doxycyclines.
This bacterial disease toxin is applicable to that chicken serum type escherichia coli, airsacculitis, pericarditis, perihepatitis, salpingitis, respiratory tract disease infect; Pig cough with asthma, pneumonia, pleuritis severe infection; Dead disease syndrome virosis, bacterial infection, shrimp pestilence, yellow head disease are stolen in aquatic animal.
Embodiment 4:
(1) takes by weighing Radix Bupleuri 15 gram, Radix Et Rhizoma Rhei 10 grams, Radix Scutellariae 5 grams, Radix Angelicae Sinensis 10 grams, Folium Isatidis 12 grams, Herba Houttuyniae 15 grams, clean oven dry (degree of dehydration is 97%) back and add SHUANGHUANGLIAN sheet 10 grams and mix;
(2), after room temperature leaves standstill and treats layering, get centrifugal, the dry 50 gram Chinese medicine ethanol extractions that get of supernatant liquid with 100ml 86% alcoholic solution lixiviate Chinese medicinal powder;
(3) in gnotobasis, the Chinese medicine ethanol extraction is mixed and promptly gets the bacterial disease toxin with 10 gram gentamycins, 10 gram pefloxacins.
This bacterial disease toxin is applicable to chicken mixed type septic chronic respiratory diseases disease, bacillosis, escherichia coli, pericarditis, perihepatitis, peritonitis, the comprehensive serious symptom of respiratory tract; Duck mixed type infectious serositis, characteristic of disease hepatitis, pneumonia main road bacillus, intestinal disease; Pig mixed infection, edema disease, escherichia coli, streptococcus mixed infection; Aquatic animal taura syudrome bacteria mixed infection, white spot syndrome, baculovirus disease, red leg disease, brown spot.
Embodiment 4:
(1) takes by weighing Radix Bupleuri 15 gram, Radix Et Rhizoma Rhei 10 grams, Radix Scutellariae 5 grams, Radix Angelicae Sinensis 10 grams, Folium Isatidis 12 grams, Herba Houttuyniae 15 grams, clean oven dry (degree of dehydration is 97%) back and add SHUANGHUANGLIAN sheet 10 grams and mix;
(2), after room temperature leaves standstill and treats layering, get centrifugal, the dry 50 gram Chinese medicine ethanol extractions that get of supernatant liquid with 100ml 86% alcoholic solution lixiviate Chinese medicinal powder;
(3) in gnotobasis, the Chinese medicine ethanol extraction is mixed and promptly gets the bacterial disease toxin with 10 gram tilmicosins, 10 gram polygynax.
This bacterial disease toxin is applicable to chicken mixed type intestinal toxicity syndrome, viral diarrhea, toxemia, gastroenteritis, necrotic enteritis, HUANGBAI(sic) dysentery, the seriously ill disease infection of intestinal; Intestinum Sus domestica toxicity syndrome, viral diarrhea, necrotic enteritis, yellow and white dysentery of piglet, infectiousness gastroenteritis.
Claims (6)
1, be used to prevent and treat the preparation method of the bacterial disease toxin of domestic animal, poultry and aquatic animal bacterial virus mixed infection disease, it is characterized in that may further comprise the steps:
(1) by mass ratio 15～20: respectively take by weighing and mix Radix Bupleuri, Radix Et Rhizoma Rhei, SHUANGHUANGLIAN, Radix Scutellariae, Radix Angelicae Sinensis, Folium Isatidis, Herba Houttuyniae at 10～20: 10～15: 5～10: 10～20: 12～20: 15～20;
(2) with 80～90% alcoholic solution lixiviates, after room temperature left standstill and treats layering, it was centrifugal, dry to get supernatant liquid;
(3) in gnotobasis with Chinese medicine ethanol extraction and one or more antiviral or antibiotics, antibiotics Western medicine powder with 3～5: 1 mass ratio mixes.
2, preparation method as claimed in claim 1 is characterized in that Western medicine is florfenicol or polymyxin.
3, preparation method as claimed in claim 1 is characterized in that Western medicine is rimantadine or levofloxacin.
4, preparation method as claimed in claim 1 is characterized in that Western medicine is taimulin or doxycycline.
5, preparation method as claimed in claim 1 is characterized in that Western medicine is gentamycin or pefloxacin.
6, preparation method as claimed in claim 1 is characterized in that Western medicine is tilmicosin or polygynax.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007100280680A CN101062171A (en) | 2007-05-18 | 2007-05-18 | Method for producing bacterial virus element medicine for preventing bacterial virus mixed infection for critter, fowl and aquatic animals |
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| CNA2007100280680A CN101062171A (en) | 2007-05-18 | 2007-05-18 | Method for producing bacterial virus element medicine for preventing bacterial virus mixed infection for critter, fowl and aquatic animals |
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Cited By (21)
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|---|---|---|---|---|
| CN102125178A (en) * | 2010-12-27 | 2011-07-20 | 豆梅英 | Feed additive for preventing and treating virus caused death of aquatic livestock and preparation method thereof |
| CN102805772A (en) * | 2012-08-23 | 2012-12-05 | 河南新正好生物工程有限公司 | Application of coptis chinensis, amur cork-tree bark, Chinese rhubarb and skullcap dysentery inhibiting particles to preparation of medicines for treating intestinal diseases of poultry, and medicinal composition formed by compounding particles |
| CN102813910A (en) * | 2012-08-09 | 2012-12-12 | 南京农业大学 | Medicine composition used for controlling poultry airsacculitis, and preparation method thereof |
| CN102861178A (en) * | 2012-10-17 | 2013-01-09 | 青岛农业大学 | Traditional Chinese medicine composition for preventing icteric hepatitis of poultry |
| CN102895377A (en) * | 2012-11-09 | 2013-01-30 | 挑战（天津）动物药业有限公司 | Pharmaceutical composition for treating livestock respiratory diseases and method for preparing pharmaceutical composition for treating livestock respiratory diseases |
| CN103006892A (en) * | 2012-12-28 | 2013-04-03 | 北京大北农动物保健科技有限责任公司 | Medicine composition for preventing and treating porcine viral diseases, and premix and batch with composition |
| CN103055281A (en) * | 2012-12-05 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating white head-mouth disease of fish and preparation method of pure Chinese medicinal composition |
| CN103127263A (en) * | 2013-02-28 | 2013-06-05 | 张丽香 | Drug for treating oyster perkinsus disease |
| CN103416610A (en) * | 2013-06-26 | 2013-12-04 | 浙江省海洋开发研究院 | Feed for cynoglossus semilaevis gunther |
| CN103655593A (en) * | 2013-12-12 | 2014-03-26 | 挑战（天津）动物药业有限公司 | Composite medicine preparation for prevention and treatment of bacterium and virus polyinfection diseases of livestock as well as preparation method and application thereof |
| CN104083731A (en) * | 2014-07-31 | 2014-10-08 | 刘吉山 | Medicament for preventing and treating mixed infection of domestic rabbits as well as preparation method and application thereof |
| CN104083730A (en) * | 2014-07-31 | 2014-10-08 | 刘吉山 | Medicine for preventing and treating mixed infection of pigs, as well as preparation method and application thereof |
| CN104096186A (en) * | 2014-07-31 | 2014-10-15 | 刘吉山 | Medicine for preventing and curing mixed infection of sheep, as well as preparation method and application of medicine |
| CN104096185A (en) * | 2014-07-31 | 2014-10-15 | 刘吉山 | Medicine for preventing and curing mixed infection among poultry, as well as preparation method and application of medicine |
| CN105288062A (en) * | 2015-10-30 | 2016-02-03 | 黄海东 | Poultry and livestock medicine for treating pneumonia and plague |
| CN105535936A (en) * | 2016-01-26 | 2016-05-04 | 苟斌书 | Compound antibacterial preparation for treating pneumonia of foxes, martens and raccoon dogs |
| CN105998321A (en) * | 2016-05-10 | 2016-10-12 | 烟台东和生态农牧科研所 | Feed additive for treating and preventing broiler mycoplasmosis and preparation method thereof |
| CN107319195A (en) * | 2017-07-20 | 2017-11-07 | 通化师范学院 | It is a kind of that there is feed addictive of preventing and treating fresh-water fishes fin rot effect and application thereof |
| CN107812166A (en) * | 2017-09-29 | 2018-03-20 | 遵义医学院 | A kind of feed addictive for preventing fish acute gastroenteritis and preparation method thereof |
| CN109303904A (en) * | 2017-07-29 | 2019-02-05 | 格特生物制药（天津）有限公司 | A kind of Chinese medicine composition and preparation method thereof for treating duck flower hepatopathy |
| CN113197868A (en) * | 2021-05-11 | 2021-08-03 | 四川省畜牧科学研究院 | Synergistic compound florfenicol particle |
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- 2007-05-18 CN CNA2007100280680A patent/CN101062171A/en active Pending
Cited By (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102125178B (en) * | 2010-12-27 | 2012-08-29 | 豆梅英 | Feed additive for preventing and treating virus caused death of aquatic livestock and preparation method thereof |
| CN102125178A (en) * | 2010-12-27 | 2011-07-20 | 豆梅英 | Feed additive for preventing and treating virus caused death of aquatic livestock and preparation method thereof |
| CN102813910A (en) * | 2012-08-09 | 2012-12-12 | 南京农业大学 | Medicine composition used for controlling poultry airsacculitis, and preparation method thereof |
| CN102813910B (en) * | 2012-08-09 | 2013-10-16 | 南京农业大学 | Medicine composition used for controlling poultry airsacculitis, and preparation method thereof |
| CN102805772A (en) * | 2012-08-23 | 2012-12-05 | 河南新正好生物工程有限公司 | Application of coptis chinensis, amur cork-tree bark, Chinese rhubarb and skullcap dysentery inhibiting particles to preparation of medicines for treating intestinal diseases of poultry, and medicinal composition formed by compounding particles |
| CN102805772B (en) * | 2012-08-23 | 2015-05-20 | 河南新正好生物工程有限公司 | Application of coptis chinensis, amur cork-tree bark, Chinese rhubarb and skullcap dysentery inhibiting particles to preparation of medicines for treating intestinal diseases of poultry, and medicinal composition formed by compounding particles |
| CN102861178A (en) * | 2012-10-17 | 2013-01-09 | 青岛农业大学 | Traditional Chinese medicine composition for preventing icteric hepatitis of poultry |
| CN102895377B (en) * | 2012-11-09 | 2015-03-11 | 挑战（天津）动物药业有限公司 | Pharmaceutical composition for treating livestock respiratory diseases and method for preparing pharmaceutical composition for treating livestock respiratory diseases |
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| CN103055281B (en) * | 2012-12-05 | 2014-12-31 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating white head-mouth disease of fish and preparation method of pure Chinese medicinal composition |
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| CN103127263A (en) * | 2013-02-28 | 2013-06-05 | 张丽香 | Drug for treating oyster perkinsus disease |
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| CN104096186A (en) * | 2014-07-31 | 2014-10-15 | 刘吉山 | Medicine for preventing and curing mixed infection of sheep, as well as preparation method and application of medicine |
| CN104096185A (en) * | 2014-07-31 | 2014-10-15 | 刘吉山 | Medicine for preventing and curing mixed infection among poultry, as well as preparation method and application of medicine |
| CN104083730A (en) * | 2014-07-31 | 2014-10-08 | 刘吉山 | Medicine for preventing and treating mixed infection of pigs, as well as preparation method and application thereof |
| CN104083731B (en) * | 2014-07-31 | 2017-05-17 | 山东省滨州畜牧兽医研究院 | Medicament for preventing and treating mixed infection of domestic rabbits as well as preparation method thereof |
| CN104083731A (en) * | 2014-07-31 | 2014-10-08 | 刘吉山 | Medicament for preventing and treating mixed infection of domestic rabbits as well as preparation method and application thereof |
| CN105288062A (en) * | 2015-10-30 | 2016-02-03 | 黄海东 | Poultry and livestock medicine for treating pneumonia and plague |
| CN105535936A (en) * | 2016-01-26 | 2016-05-04 | 苟斌书 | Compound antibacterial preparation for treating pneumonia of foxes, martens and raccoon dogs |
| CN105998321A (en) * | 2016-05-10 | 2016-10-12 | 烟台东和生态农牧科研所 | Feed additive for treating and preventing broiler mycoplasmosis and preparation method thereof |
| CN107319195A (en) * | 2017-07-20 | 2017-11-07 | 通化师范学院 | It is a kind of that there is feed addictive of preventing and treating fresh-water fishes fin rot effect and application thereof |
| CN109303904A (en) * | 2017-07-29 | 2019-02-05 | 格特生物制药（天津）有限公司 | A kind of Chinese medicine composition and preparation method thereof for treating duck flower hepatopathy |
| CN107812166A (en) * | 2017-09-29 | 2018-03-20 | 遵义医学院 | A kind of feed addictive for preventing fish acute gastroenteritis and preparation method thereof |
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