CN103127263A - Drug for treating oyster perkinsus disease - Google Patents
Drug for treating oyster perkinsus disease Download PDFInfo
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- CN103127263A CN103127263A CN2013100653840A CN201310065384A CN103127263A CN 103127263 A CN103127263 A CN 103127263A CN 2013100653840 A CN2013100653840 A CN 2013100653840A CN 201310065384 A CN201310065384 A CN 201310065384A CN 103127263 A CN103127263 A CN 103127263A
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Abstract
The invention discloses a drug for treating oyster perkinsus disease, which comprises the following raw materials by weight: 20-45 parts of radix bupleuri, 2-4 parts of glucan, 12-14 parts of franzenbach rhubarb root and rhizome, 21-24 parts of Scutellaria baicalensis, 6-8 parts of Coptis chinensis, 12-25 parts of liquorice, 12-18 parts of motherwort, 3-5 parts of florfenicol, 0.05-0.4 parts of abamectin, 6-14 parts of mebendazole and 40-80 parts of starch. According to the invention, Chinese composition of and western composition are combined so that the drug provided by the invention has good treatment effect for oyster perkinsus disease, and has treatment both symptoms and root causes, so that the infection rate of oyster perkinsus disease can be reduced.
Description
Technical field:
The present invention relates to technical field of pharmaceuticals, specifically a kind ofly treat the medicine that large oyster is sent the JINCHONG disease.
Background technology:
Large oyster is a kind of seafood, and the formal name used at school Crassostrea rivularis is one of Qiezhou four large famous and precious marine products, and meat can be eaten raw, and is nutritious, and delicious flavour have the title of " marine milk ", also can be used as medicine simultaneously.In the situation that current high density, intensive culture, particularly abominable water quality adds the feedstuff of low-quality, add the abuse disinfecting drug, in the breeding process of large oyster, disease frequently occurs, a kind of disease that wherein impact is larger is for sending JINCHONG sick, its pathogen is mainly sea water and sends JINCHONG, mainly encroaches on the large oyster more than a year.Mortality rate also increases with advancing age, but in each department, difference is arranged again, and infection rate reaches as high as group's 90%～99%.
The large oyster early symptom that infects, polypide parasitic site tissue is inflamed, and produces fibre modification thereupon, to the later stage, histolysis widely, formative tissue abscess or edema.Large oyster health is become thin gradually, and growth stops, and gonadal growth is also hindered, and infects that serious large oyster faucal opens and extremely.For this disease, main simple medicine or the simple condition of controling environment of adopting treated at present, but the effect for the treatment of is general.
Summary of the invention:
The object of the invention is to overcome deficiency of the prior art, and a kind of with low cost, medicine that the large oyster of eutherapeutic treatment is sent the JINCHONG disease is provided.
For solving the problems of the technologies described above, the present invention by the following technical solutions:
A kind ofly treating the medicine that large oyster is sent the JINCHONG disease, is to be made by the raw material of following weight parts:
20～45 parts of Radix Bupleuri, 2～4 parts of glucosans, 12～14 parts of Radix et Rhizoma Rhei Franzenbachii, 21～24 parts of Radix Scutellariaes, 6～8 parts of Rhizoma Coptidis, 12～25 parts, Radix Glycyrrhizae, 12～18 parts of Herba Leonuris, 3～5 parts of florfenicols, 0.05～0.4 part of avilamycin, 6～14 parts of mebendazoles, 40～80 parts of starch.
In the preparation, take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, pulverize, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
The characteristic of component of the present invention:
1, Radix Bupleuri: perennial herb, main root is cylindrical, and matter is hard, and root is directly given birth to.Its composition of Radix Bupleuri mainly contains saikoside (four kinds of saikosapoins a, b, c, d), sterol, volatile oil (bupleurumol, eugenol etc.), fatty acid (oleic acid, linoleic acid, Palmic acid, stearic acid etc.) and polysaccharide etc.
2, glucosan: be the chain macromolecule material that a class has glucose molecule β-1,3 and β-1,6 glycosidic bond to be formed by connecting, comprise fungus polysaccharide, Sargassum polysaccharides, chitosan etc.With β-1,3/1,6-D glucosan etc. are common at present.Glucosan enters in animal body, can with the special receptors bind of humoral factor and immunocyte, thereby swash intravital immune system.For Fish, glucosan improves reactive oxygen free radical output and hemocytolysis effect by promoting that macrophage shifts to focus, and parasiticide, bactericidal activity, antiviral activity and the stress ability of body are improved.For crustacean and shellfish, glucosan produces activated phenol oxidase by activating pro-phenoloxidase system, participates in several ways the defense reaction of body with approach.To its immunological enhancement of many animals, can excite the activity of complement, lysozyme and macrophage, strengthen the ability that large oyster parasiticide, antibacterial etc. infect; Share with vaccine and can significantly improve vaccine valence; Improve cultivated animals rate of body weight gain, the survival rates such as large oyster, and reduce feed coefficient.
3, Radix et Rhizoma Rhei Franzenbachii: various bacteria is had inhibitory action, comprising escherichia coli, staphylococcus, dysentery bacterium, bacillus pyocyaneus etc. are had good inhibitory action, but heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, stomach function regulating antidiarrheal are for sending the disease that JINCHONG causes that good curative effect is arranged.
4, Radix Scutellariae: be used as medicine with root, the nature and flavor bitter cold, heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Have broad-spectrum antibacterial action, the anti-inflammatory allergy has analgesic, function of gallbladder promoting, calm effect simultaneously.
5, Rhizoma Coptidis: heat clearing and damp drying is arranged, the effect of eliminating fire and detoxication.Its flavor entrance is extremely bitter.
6, Radix Glycyrrhizae: the root of Radix Glycyrrhizae and rhizome contain the triterpene saponin glycyrrhizic acid, i.e. glycyrrhizin, and this glycosides is without haemolysis, and enoxolone has.Also tell multiple flavone component from Radix Glycyrrhizae, glycyrrhizin, isoliquiritigenin, liquirtin etc. are wherein arranged.The property of medicine is sweet, and is flat.Have detoxifcation, antiinflammatory, blood pressure lowering, analgesia, antiallergic action.
7, Herba Leonuri: herb contains leonurine 0.05%(and spends the initial stage to contain trace, and the flowers are in blossom, and increase mid-term gradually), stachydrine, stachydrine, rutin, Fumaric acid, leonurine first, second.The Herba Leonuri Sibirici herb contains alkaloid 0.05%.In herb, the content of leonurine changed with the period of blooming, and the initial stage content of spending is very little, and it is 0.01-0.03% that 7-8 spends mid-term content the middle of the month, reach as high as 0.04%, and contain stachydrine, leonurine, 4-guanidine radicals butanols-Isosorbide-5-Nitrae-guanidine radicals butanoic acid, arginine, trace rutin, stachyose, plant sterol, resin, fatty oil, lauric acid, linoleic acid, β-linolenic acid and oleic acid.Bitter in the mouth, suffering, cold nature.Promoting blood flow to regulate menstruation is arranged, eliminating blood stasis to promote regeneration of blood, the function of inducing diuresis to remove edema.
8, florfenicol: be the structure homologue of chloromycetin, the mechanism of action and antimicrobial spectrum are similar with thiamphenicol to chloromycetin, can be combined with the 50S subunit, suppress the phthaloyl based transferase, thereby suppress the extension of phthalein chain, and interferencing protein is synthetic.Florfenicol has structurally replaced in chloromycetin, thiamphenicol on propane chain 3 carbon locations-OH with the F atom; stoped the antibacterial Acetylase in this locational acetylation; therefore be not subjected to this enzyme affect and be inactivated; and Acetylase is relevant through the plasmid-mediated drug resistance to chloromycetin, thiamphenicol with antibacterial; therefore florfenicol can not produce similar chloromycetin, the plasmid-mediated drug resistance of thiamphenicol, and still responsive to many chloromycetin Resistant strains.Be mainly used in preventing and treating Fish by Aeromonas, pseudomonas, vibrio, bend the disease that the antibacterial such as oar bacillus, streptococcus, pasteurella, Nocard's bacillus, Edwardsiella, mycobacterium or parasite cause.
9, avilamycin: the general content of avilamycin sterling is white or little yellow crystalline powder more than 98%.Under low dosage, multiple parasitism in various pests and animal body is all had and efficiently kill activity, particularly nematicide and arthropod all have the good effect of killing to endoparasite and ectoparasite.Avilamycin belongs to a kind of macrolide disaccharidase compounds, and it has many parasites tags and stomach poison function, and its mechanism of action is to disturb nervous physiology movable, stimulates release y aminobutyric acid to cause its nerve conduction and is suppressed and paralyses to cause and get killed.
10, mebendazole: be white, off-white color or micro-yellow powder.Can cause that polypide enterocyte slurry microtubule disappears, can irreversiblely suppress polypide to the utilization of glucose, cause polypide glycogen and adenosine triphosphate to exhaust, the polypide growth promoter is obstructed, maybe can extend retaining of the interior hydrolytic enzyme of cell, thereby accelerate the dissolving of polypide cortex.Be the anthelmintic drug of efficient, wide spectrum, low toxicity, be commonly used to kill parasitism.
11, starch: mainly playing carrier function, is also binding agent simultaneously, has certain adhesive effect.
The beneficial effect that the present invention has:
The present invention is with above-mentioned each component organic assembling, complement each other, can bring into play to greatest extent the function of each component, medicinal herb components Radix Bupleuri wherein, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae, Herba Leonuri adopt superfine communication technique, effective ingredient is stripping fully, arrange in pairs or groups simultaneously Western medicine glucosan, florfenicol, avilamycin, mebendazole, starch, Chinese and Western component function synergism, send the JINCHONG disease to have good therapeutical effect to large oyster, and treating both the principal and secondary aspects of a disease, thereby reduce its disease infection rate.
The specific embodiment:
The invention will be further described with embodiment for the below, but the present invention is not limited to these embodiment.
Embodiment 1
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 20 parts of Radix Bupleuri, 2 parts of glucosans, 12 parts of Radix et Rhizoma Rhei Franzenbachii, 21 parts of Radix Scutellariaes, 6 parts of Rhizoma Coptidis, 12 parts, Radix Glycyrrhizae, 12 parts of Herba Leonuris, 3 parts of florfenicols, 0.05 part of avilamycin, 6 parts of mebendazoles, 40 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 2
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 45 parts of Radix Bupleuri, bextran 45 part, 14 parts of Radix et Rhizoma Rhei Franzenbachii, 24 parts of Radix Scutellariaes, 8 parts of Rhizoma Coptidis, 25 parts, Radix Glycyrrhizae, 18 parts of Herba Leonuris, 5 parts of florfenicols, 0.4 part of avilamycin, 14 parts of mebendazoles, 80 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 3:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 4:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.3 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 5:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 12 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 6:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 3 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 7:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 35 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 8:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, bextran 45 part, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 9:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 14 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 10:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 24 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 11:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 8 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 12:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 22 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 13:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 17 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 14:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 60 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Embodiment 15:
A kind ofly treat the medicine that large oyster is sent the JINCHONG disease, take by weight 30 parts of Radix Bupleuri, 3 parts of glucosans, 13 parts of Radix et Rhizoma Rhei Franzenbachii, 22 parts of Radix Scutellariaes, 7 parts of Rhizoma Coptidis, 18 parts, Radix Glycyrrhizae, 15 parts of Herba Leonuris, 4 parts of florfenicols, 0.2 part of avilamycin, 10 parts of mebendazoles, 70 parts of starch.
Preparation method:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, carry out conventional micronizing to 300 order, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
Experimental example:
The large oyster of Qinzhou plant, the death of large oyster occurs in summer and early autumn (8～JIUYUE), and along with weather turns cold, water temperature descends, death also reduces later on.Environmental condition before the Epidemics disease is higher water temperature (30 ℃) and higher salinity (30 ‰), the raiser uses general insecticidal materials, consumption is 100g/ mu. rice, after 3 days, microscopy finds that each visual field also exists a large amount of sea water to send JINCHONG, large oyster infection rate is more than 70%, and uses medicine dose 50g/ mu of the present invention. rice, microscopy after 3 days, as seen the sea water in the visual field is sent the dead decomposition of JINCHONG, and it is more than 30% that large oyster is sent the sick infection rate of JINCHONG.
Claims (2)
1. treat the medicine that large oyster is sent the JINCHONG disease for one kind, it is characterized in that being made by the raw material of following weight parts:
20～45 parts of Radix Bupleuri, 2～4 parts of glucosans, 12～14 parts of Radix et Rhizoma Rhei Franzenbachii, 21～24 parts of Radix Scutellariaes, 6～8 parts of Rhizoma Coptidis, 12～25 parts, Radix Glycyrrhizae, 12～18 parts of Herba Leonuris, 3～5 parts of florfenicols, 0.05～0.4 part of avilamycin, 6～14 parts of mebendazoles, 40～80 parts of starch.
2. a kind ofly according to claim 1 treat the medicine that large oyster is sent the JINCHONG disease, it is characterized in that: its preparation method is:
Take Radix Bupleuri, Radix et Rhizoma Rhei Franzenbachii, Radix Scutellariae, Rhizoma Coptidis, Radix Glycyrrhizae and Herba Leonuri by formula, pulverize, then mix with glucosan, florfenicol, avilamycin, mebendazole and the starch of formula ratio, stir, and get final product.
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Application publication date: 20130605 |