CN102600441A - Compound tincture for preventing and controlling insect bites and stings of livestock - Google Patents

Abstract

The invention discloses compound tincture for preventing and controlling insect bites and stings of livestock. The compound tincture is mainly prepared by mixing 24 raw materials, such as 40-50 parts of cortex meliae, 40-50 parts of mint leaf, 40-50 parts of rangooncreeper fruit, 40-50 parts of Chinese torreya seed, 40-50 parts of cushaw seed, 40-50 parts of betel nut, 30-40 parts of shrubalthea bark, 30-40 parts of camphor, 30-40 parts of Chinese hibiscus leaf, 30-40 parts of rosin, 30-40 parts of denseflower indigo leaf, 30-40 parts of Japanese peristrophe herb, 20-30 parts of philippine violet herb, 20-30 parts of common carpesium fruit, 20-30 parts of adder tongue herb, 10-20 parts of erythromycin and 10-20 parts of vitamin B. Various effective components are percolated, homogenized and sterilized to obtain an external tincture. The external tincture has remarkable curative effects for body surface diseases caused by pathogenic microorganisms and other reasons as well as quick response and high cure rate.

Description

A kind of compound spirit of preventing and treating the domestic animal mosquito bite

Technical field

The invention belongs to field of traditional Chinese veterinary, specifically a kind of compound spirit of preventing and treating the domestic animal mosquito bite.

Background technology

Summer and autumn, mosquito is movable rampant, not only sucks the blood of poultry, captures nutrition, and excretes poison, and makes to be bitten position generation erubescence swell and itch, spreads disease.Cause the poultry that are injured to become thin gradually, poor growth, dysplasia, serious also causes death.Prevent the mosquito bite domestic animal, remove and do environmental health well, adopt medicine to kill and drive method with mosquito incense.

Also have, clinically cause behind the mosquito bite: the body surface disease that pathogenic microorganism and other reason cause, tinea capitis, tinea corporis and cruris, tinea manus and pedis, tinea versicolor, dermatocandidiasis, tinea unguium, sporotrichosis to mainly containing.Main antibiotic, the hormone medicine of leaning on treated, yet, owing to antibiotic, hormone medicine have bigger side effect to the domestic animal body surface; So; Seek a kind of body and can not produce chemical sproofly, can kill multiple pathogen, can play the new medicine of quick rehabilitative action to the damaged skin mucosa it; To substitute or to reduce the application of antibiotic, hormone medicine, be one of striving direction of those skilled in the art.

Summary of the invention

The inventor is through research repeatedly, and through verification experimental verification, found a kind of compound spirit of preventing and treating the domestic animal mosquito bite that better curative effect is arranged finally, and this externally applied liniment has significant curative effect to the body surface disease that pathogenic microorganism and other cause of disease cause.

Technical assignment of the present invention provides a kind of compound spirit of preventing and treating the domestic animal mosquito bite.

Another one technical assignment of the present invention provides the method for preparing of this tincture.

The present invention separates as follows a kind of compound spirit side that prevents and treats the domestic animal mosquito bite:

Medicament selection Cortex Meliae of the present invention, mentha leave, Fructus Quisqualis, Semen Torreyae, Semen Cucurbitae, Semen Arecae, Cortex Hibisci, Camphora, Folium Hibisci Rosae-Sinensis, Colophonium, Folium Indigoferae teysmannii, Herba Peristrophes, Herba Violae, Fructus Carpesii, Herba Ophioglossi, Folium Acori graminei, Radix Sophorae Tonkinensis, Borneolum Syntheticum, Rhizoma Zingiberis Recens, Bulbus Allii, Chinese liquor, Oleum Glycines, erythromycin, vitamin B make up as the function raw material; With Cortex Meliae, mentha leave, Fructus Quisqualis, Semen Torreyae, Semen Cucurbitae, Semen Arecae is monarch drug; Can heat radiation, pain relieving, antipruritic, sterilize, go stagnated fire; Because multiple pathogen is had inhibitory action; In prescription, played anti-inflammation, antalgesic-antipruritic, the pivotal role of treatment various skin membrane disease.Cortex Hibisci, Camphora, Folium Hibisci Rosae-Sinensis, Colophonium, Folium Indigoferae teysmannii, Herba Peristrophes are ministerial drug, have broad-spectrum sterilization, disinfectant activity, and golden yellow staphylococcus, escherichia coli, Bacillus typhi, dysentery bacterium are all had strong inhibitory action.Assist a ruler in governing a country jointly to play the merit of the malicious dissipating blood stasis of a surname, anti-inflammation, diffusing swollen pain relieving, removing dampness to relieve itching in league with Herba Violae, Fructus Carpesii, Herba Ophioglossi, Folium Acori graminei, Radix Sophorae Tonkinensis, Borneolum Syntheticum, Rhizoma Zingiberis Recens, Bulbus Allii, Chinese liquor, Oleum Glycines, erythromycin, vitamin B.These material combination make each efficacy of drugs produce synergism, and it mixes the back and produces peat-reek, can mosquito repellent; Thereby effectively preventing domestic animal mosquito bite.

A kind of compound spirit of preventing and treating the domestic animal mosquito bite is to be processed by following weight portion raw material:

Cortex Meliae 40-50 part; Mentha leave 40-50 part; Fructus Quisqualis 40-50 part; Semen Torreyae 40-50 part; Semen Cucurbitae 40-50 part; Semen Arecae 40-50 part; Cortex Hibisci 30-40 part; Camphora 30-40 part; Folium Hibisci Rosae-Sinensis 30-40 part; Colophonium 30-40 part; Folium Indigoferae teysmannii 30-40 part; Herba Peristrophes 30-40 part; Herba Violae 20-30 part; Fructus Carpesii 20-30 part; Herba Ophioglossi 20-30 part; Folium Acori graminei 20-30 part; Radix Sophorae Tonkinensis 20-30 part; Borneolum Syntheticum 20-30 part; Rhizoma Zingiberis Recens 10-20 part; Bulbus Allii 10-20 part; Chinese liquor 10-20 part; Oleum Glycines 10-20 part; Erythromycin 10-20 part; VitaminB10-20 part;

Method for preparing comprises:

A, Borneolum Syntheticum is dissolved in the Chinese liquor by formula proportion;

B, step 1 gained solution and Oleum Glycines, erythromycin, vitamin B are fully with must stock solution after water mixes subsequent use;

C, by formula proportion Cortex Meliae, mentha leave, Fructus Quisqualis, Semen Torreyae, Semen Cucurbitae, Semen Arecae, Cortex Hibisci, Camphora, Folium Hibisci Rosae-Sinensis, Colophonium, Folium Indigoferae teysmannii, Herba Peristrophes, Herba Violae, Fructus Carpesii, Herba Ophioglossi, Folium Acori graminei, Radix Sophorae Tonkinensis, Rhizoma Zingiberis Recens, Bulbus Allii are screened → weighing assorts → dries → after pulverizing; Put into and be equipped with that to contain 5 times of amount concentration be that 80% (V/V) Chinese liquor solution mix to stir, flood and adjust flow velocity after 24 hours; When the existing stock solution of potching liquid 3/4 the time stop percolation, press residue, it is for use to get percolation;

D, step 2 mixed the subsequent use stock solution in back mix, stir with step 3 percolate, then under 0-10 ℃ of temperature with ultrasound wave homogenize 10-30 minute, sterilize, packing is finished product.

Usage and dosage: get medical Cotton Gossypii or cotton during use, be equal on the area average price at impaired skin and smear evenly, every day six times, cure next day.

A kind of compound spirit of preventing and treating the domestic animal mosquito bite is to be processed by following weight portion raw material:

Cortex Meliae 42-48 part; Mentha leave 42-48 part; Fructus Quisqualis 42-48 part; Semen Torreyae 42-48 part; Semen Cucurbitae 42-48 part; Semen Arecae 42-48 part; Cortex Hibisci 32-38 part; Camphora 32-38 part; Folium Hibisci Rosae-Sinensis 32-38 part; Colophonium 32-38 part; Folium Indigoferae teysmannii 32-38 part; Herba Peristrophes 32-38 part; Herba Violae 22-28 part; Fructus Carpesii 22-28 part; Herba Ophioglossi 22-28 part; Folium Acori graminei 22-28 part; Radix Sophorae Tonkinensis 22-28 part; Borneolum Syntheticum 22-28 part; Rhizoma Zingiberis Recens 12-18 part; Bulbus Allii 12-18 part; Chinese liquor 12-18 part; Oleum Glycines 12-18 part; Erythromycin 12-18 part; Vitamin B12-18 part;

A kind of compound spirit of preventing and treating the domestic animal mosquito bite is to be processed by following weight portion raw material:

45 parts of Cortex Meliaees, 45 parts of mentha leavves, 45 parts of Fructus Quisqualis, 45 parts of Semen Torreyaes, 45 parts of Semen Cucurbitaes, 45 parts of Semen Arecaes, 35 parts of Cortex Hibiscis, 35 parts of Camphoras, 35 parts of Folium Hibisci Rosae-Sinensiss, 35 parts of Colophonium, 35 parts of Folium Indigoferae teysmanniis, 35 parts of Herba Peristrophess, 25 parts of Herba Violaes, 25 parts of Fructus Carpesiis, 25 parts of Herba Ophioglossis, 25 parts of Folium Acori gramineis, 25 parts of Radix Sophorae Tonkinensiss, 25 parts of Borneolum Syntheticums, 15 parts in Rhizoma Zingiberis Recens, 15 parts in Bulbus Allii, 15 parts of Chinese liquor, 15 parts in Oleum Glycines, 15 parts in erythromycin, VITAMIN B15 part;

The present invention relates to herbal pharmacology and the property of medicine is following:

Cortex Meliae:

Not [nature and flavor] " not Lu ": " be slightly cold." " Japan hanako materia medica ": " hardship, little poison." " the medical center nationality is wanted ": " is big bitter, Great Cold."

[function cures mainly] heat clearing away, dampness, parasite killing.Control ascarid, pinworm, rubella, scabies.

[pharmacological action] 1, anthelmintic action: show that through the pig test this medicine decoct or alcohol extract all have inhibition so that the paralysis effect to ascaris suum.The effective ingredient that drives the ascarid effect is a Toosendanin, and is stronger than the effect of ethanol extraction.The Toosendanin of low concentration (1:5000-9000); Whole piece ascaris suum and sections (head and middle part) thereof there is tangible excitation; Show as spontaneous activity and strengthen, occur unusual violent contraction off and on, destroy its laws of motion property (movable strengthen with weaken alternate); Continue 10-24 hour, change spastic contraction at last gradually over to.Toosendanin can see through polypide Epidermis, directly act on ascarid muscle, upset its energy metabolism, cause contraction fatigue and spasm.The Fructus Toosendan rope of this concentration is not blocked by atropine the excitation of ascarid nerve-muscle, and the prompting Toosendanin is not a cholinomimetic.The Toosendanin of high concentration (l:1000) to ascaris suum particularly the neuroganglion of head the paralysis effect is arranged.This paralysis effect possibly be that polypide receives to be the result that intermittent cramp shrinks behind the drug effect.Measure the cholinesterase activity of polypide homogenate respectively and breathe zymolysis through Ammon method and Warburg apparatus, result's proof does not all have obviously influence, shows that Toosendanin is not to work through carbohydrate metabolism.Can find out in the experimental result of ATP from ascarid muscle and Phos that in addition Toosendanin can make the catabolism quickening of ATP, thereby cause ascarid that the energy short supply is arranged and cause fatigue of contraction, and be excreted.The Cortex Meliae medicinal liquid (25%-50%) of high concentration also has the paralysis effect external to the mice pinworm. 2, to the influence of respiratory center:Heavy dose of Toosendanin (every rat, vein or intramuscular injection 2mg) can cause that rats breathing is depleted.This mainly is owing to the inhibitory action of this composition to maincenter.Medulla oblongata respiratory center position directly gives Toosendanin (every rat 0.10-0.15mg), can support The above results.The respiration inhibition that the central stimulants nikethamide causes Toosendanin has slight antagonism .3, to the influence of neuromuscular propagation function: Toosendanin has rat and irreversibly checks the muscle contraction that indirect stimulation causes, but the excitement that does not affect the nerves conduction does not reduce the reaction of muscle to direct stimulation yet; Toosendanin is 1 and optionally acts on presynaptic neuromuscular transmission blocker.Its site of action is at the presynaptic teleneuron, and model of action is the acetylcholine release that suppresses to excite nerve and bring out.Electron microscope observation shows that Toosendanin has tangible effect to the ultrastructure of white mice neuromuscular junction, shows that the synaptic space width increases and the synaptic vesicle decreased number.These two kinds of variations do not appear at same joint simultaneously.4, anti-botulism: Toosendanin has therapeutical effect to the botulism animal.To the mice of lethal dose A type botulism, poisoning gave Toosendanin in back 6 hours, and obvious therapeutic action is arranged; To the monkey of lethal dose A type botulism, poisoning gave Toosendanin in back 24 hours, can cure animals more than half; To the mice of Type B botulism, Toosendanin also has protective effect.In addition, Toosendanin can obviously strengthen the therapeutical effect of antitoxic serum to botulism mice and rabbit.5 of papillary electromyography and mechanical characteristics: Toosedarin concentration-dependent manner the complex extreme fast reaction potential duration of 90% (APD? 90) extended with barium chloride blocked Ik1, prolonged APD90 cancel role TSN TSN so bad slow reaction electrical e Pian PD prolongation and contractile force (FC) Enhanced with barium chloride, cancel TSN above role, but the role of prolonged APD exists.In addition, Toosendanin can make isolated frog heart shrink allorhythmia, can recover automatically in lasting l hour.6, other effects:Plain (200mg/kg) rabbit filling stomach of chinaberry and concentration are that the Toosendanin of 0.2 * 10 (4) mg all has remarkable increase to the tension force and the contractility of rabbit on the throne and isolated rabbit intestinal.Concentration is that the Toosendanin of 0.2 * l0 (3) mg can make myenteron present spastic contraction.This excitation can be resisted by diphenhydramine, and is not blocked by atropine.10% Cortex Meliae infusion has inhibitory action to multiple pathogenic fungus.Melia extract for treating mouse experiment property schistosomiasis mansoni, the aspects such as borer population and hatching test of living from the animal body internal memory confirm that certain curative effect is arranged.

Herba Menthae:

[meridian distribution of property and flavor] cool in nature, acrid in the mouth;

The effect of [function] irritation causes trachea to produce new secretion, and makes stiff mucus be easy to get rid of, so eliminate the phlegm, germ-resistant effect.

Fructus Quisqualis:

[meridian distribution of property and flavor] sweet in the mouth warm in nature is gone into spleen, stomach, large intestine channel,

The effect of [effect] tool parasite killing, removing food stagnancy, spleen invigorating.Its sweet temperature is the temperature of gentleness, and different non-warm-dryness syndrome is comparable, so can help movingization of the diet, stagnates in the intestinal and dredge, and is rich in fat liquid, so sliding sharp circulation.Semen Torreyae:

[nature and flavor] are sweet, and are flat.1. " herbal classic ": " sweet in the mouth, temperature." 2. " not Lu ": " be poisonous." 3. " a thousand pieces of gold dietetic therapy ": " sweet in the mouth is flat puckery, nontoxic."

[return through] gone into lung, stomach, large intestine channel.1. " Bencao Jingshu ": " lunar, the Yangming Channel of starting with." 2. " book on Chinese herbal medicine is newly organized ": " goes into stomach, spleen, large intestine channel, goes into lung again."

[function cures mainly] parasite killing, removing food stagnancy is moisturized.Control abdominal pain due to worm stagnation, infantile malnutrition, cough caused by dryness, constipation, hemorrhoid.1. " herbal classic ": " pathogen in the main abdomen is gone three worms, and Serpentis stings." 2. " not Lu ": " main five hemorrhoid." 3. TAO Hong-Jing: " treated cun white." 4. the Meng numerous: " made us and can be eaten, and rapid digestion of food helps muscles and bones, and the field headquarters is defended, and makes eye bright." 5. " daily book on Chinese herbal medicine ": " kills interventral big small worm, and children's's Huang is thin, and promptly healing of malnutrition due to parasitic infestation person's food arranged in the abdomen.Be with shell to chew carefully food down, expectorant again." 6. " giving birth to the chief editor ": " controlled cough, nebulousurine, supporing yang road." 7. essentials of Matea Medica: " lung moistening, parasite killing." 8. " herbal classic is met former ": " and the same merit of Fructus Quisqualis." 9. " book on Chinese herbal medicine is new again ": " controlled lung-fire, spleen invigorating soil, and QI invigorating is reduced phlegm, and cough-relieving is coughed, and breathes out to breathe heavily eliminating blood stasis to promote regeneration of blood surely."

Semen Cucurbitae:

[nature and flavor] property is flat, sweet in the mouth.

[function cures mainly] anthelmintic, detumescence.Be used to control cestode, ascarid, puerperal brothers' edema, pertussis, hemorrhoid.

Semen Arecae:

[meridian distribution of property and flavor] is bitter, hot, warm; Go into spleen, stomach, large intestine channel.

[function] parasite killing, removing mass, the therapeutic method to keep the adverse QI flowing downwards, row water.Control malnutrition due to parasitic infestation, dyspepsia, abdominal distention, heavy behind the dysentery, malaria, edema, beriberi, accumulation of phlegm in the hypochondrium, crux.

Cortex Hibisci:

[meridian distribution of property and flavor] is cold; Sweet, bitter; Return large intestine, liver, spleen channel

[effect] heat clearing away, dampness removing, detoxifcation, antipruritic.Be used to control hemorrhoidal hamorrhage and rush down blood, dysentery is controlled proctoptosis, leucorrhea, hemorrhoid, scabies.

Camphora:

[meridian distribution of property and flavor] suffering, temperature.

[function cures mainly] sensible ward off dirty, warming middle-JIAO to relieve pain, dampness removing parasite killing.Be used for cold-damp and vomit and diarrhoea stomach abdomen pain; External is controlled scabies, tinea, dental caries and is had a pain.

Folium Hibisci Rosae-Sinensis

[nature and flavor] are " detailed outline " 1.: " sweet, flat, nontoxic." 2. " Guangxi Chinese medicinal herbal ": " puckery, property is flat."

[function cures mainly] controlled carbuncle, skin infection, epistaxis.1. " detailed outline ": " control the carbuncle mumps, get leaf or spend same white Folium Hibisci Mutabilis, Herba Arctii leaf, whitish honey to grind cream and apply it." 2. " Fujian traditional herbal medicine ": " separated pyretic toxicity, subduing inflammation." 3. " Luchuan book on Chinese herbal medicine ": " removing pathogenic heat from blood and toxic substance from the body.Control the heat in blood epistaxis, pruritus, skin infection." 4. " Nanning City's medicine will ": " is smashed deposited abscess to pieces."

Colophonium:

[meridian distribution of property and flavor] is bitter sweet, temperature.1. " herbal classic ": " bitter in the mouth, temperature." 2. " not Lu ": " sweet, nontoxic." 3. " property of medicine opinion ": " and sweet in the mouth, flat." 4. " book on Chinese herbal medicine is just ": " bitter in the mouth is hot, temperature." go into liver, spleen channel.1. " Thunder God concoct the property of medicine separate ": " go into spleen, lung two warps." 2. " must join book on Chinese herbal medicine ": " lunar, the sufficient Yangming Channel of starting with." 3. " book on Chinese herbal medicine is looked for the truth ": " go into liver, spleen.”

[function cures mainly] dispeiling pathogenic wind and removing dampness, the granulation promoting pain relieving is applicable to carbuncle furuncle infections, eczema, traumatic hemorrhage, burn and scald.

Folium Indigoferae teysmannii:

[meridian distribution of property and flavor] acrid in the mouth; Bitter; Warm in nature.

[function cures mainly] parasite killing; Antipruritic tinea pedis; Scabies.

Herba Peristrophes:

[meridian distribution of property and flavor] is hot, little hardship, cold.

[function cures mainly] juice induces sweat heat-clearing and toxic substances removing, spasmolytic.Be used for flu, laryngopharynx swelling and pain, diphtheria, infantile dyspepsia, infantile hyperpyrexia, carbuncle furuncle and phyma poison, venom.

Herba Violae:

[meridian distribution of property and flavor] is bitter, hot, cold, nontoxic; GUIXIN, Liver Channel.

[function cures mainly] can be used as medicine, its mildly bitter flavor cold in nature, heat-clearing and toxic substances removing, removing heat from blood detumescence.Cure mainly jaundice, dysentery, mastitis, conjunctival congestion and swelling pain, pharyngitis; Traumatic injury, carbuncle, venom etc. are controlled in external application.

Fructus Carpesii:

[meridian distribution of property and flavor] toil, flat, poisonous.1. Tang Materia Medica: " bitter in the mouth, flat, slightly poisonous." 2. " detailed outline ": " and toil, slightly poisonous." 3. " the medical center bun is wanted ": " toil, temperature." go into spleen, stomach, Liver Channel; " herbal classic is met former " " " cloudy Liver Channel of going into to faint.”

[effect] parasite killing, heat-clearing and toxic substances removing, invigorating the spleen and regulating the stomach.

[curing mainly] controlled abdominal pain due to worm stagnation, trichomonas vaginitis; It has anthelmintic action, and 1% Fructus Carpesii is joined 5 and drips among the human physiology saline solution 25ml, heats 37 ℃ and puts National People's Congress cestode again, and 1-2 minute as a result promptly dead.

Herba Ophioglossi:

[nature and flavor] sweet in the mouth is flat, nontoxic.

[function cures mainly] heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis.1. " vegetation is the side just ": " the heat clearing away poison removes wind heat.Control scrotum kind pain, furuncle is swollen vicious, breast abdomen stagnated blood, snake venom." 2. " classification medical herbs property ": " controlled the son of itching, the sore that disappears, traumatic injury, toxic swelling." 3. " Sichuan Chinese medicinal herbal ": " heat-clearing and toxic substances removing, subduing inflammation.Control dog and hinder scabies."

Folium Acori graminei:

[nature and flavor] are hot, temperature is gone into the heart, lung two warps.

Skin ulcer, parasite killing are treated in [function cures mainly] detoxifcation.Control skin ulcer scabies, leprosy, impetigo.

Radix Sophorae Tonkinensis:

[meridian distribution of property and flavor]: hardship, cold.Go into the heart, lung, large intestine three warps;

[function] relieves inflammation or internal heat, detoxifcation, detumescence, pain relieving.Function cures mainly: control retropharyngeal abscess, and acute throat trouble, sore throat, gingival swelling and pain, the dyspnea with fullness of the chest heat syndrome cough, jaundice, dysentery, haemorrhoids, heat is swollen, tinea alba, scabies, Serpentis, worm, lyssodexis.

Borneolum Syntheticum:

[meridian distribution of property and flavor] acrid in the mouth, hardship are slightly cold; GUIXIN, spleen, the lung hydrocarbon.

[effect] refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.

Rhizoma Zingiberis Recens:

[Nature and flavor] hot, tepor, return lung taste warp

[effect] relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, solving toxin of fish and crab is separated poison of drug; Deliver, cold expelling, preventing or arresting vomiting is opened expectorant, carbuncle skin ulcer.

Bulbus Allii:

[meridian distribution of property and flavor] is warm in nature, and acrid in the mouth is flat; People's spleen, stomach, lung meridian.

[function cures mainly] is used for that dysentery is had loose bowels, pulmonary tuberculosis. pertussis, intestinal parasitic disease (ancylostome, enterobiasis), diseases such as sore and toxic.1. diffusing carbuncle removing food stagnancy, detoxifcation parasite killing: cure mainly carbuncle sore tumefacting virus, tinea skin ulcer pruritus.Mash the outer wiping of external application or section.2. detoxifcation: be used for the pulmonary tuberculosis pertussis, dysentery is had loose bowels.3. parasite killing: be used for ancylostomiasis,, can join the same decoction of anthelmintic around parasitosis.To ancylostomiasis, these article also can prevent usefulness, before the work of going to the field, Bulbus Allii are mashed, and are applied to extremity.The opposing connection parasitosis also can be mashed these article, add vegetable oil a little, be applied to around the anus just before going to bed.In addition, these article are eaten raw also and can be prevented and treated influenza.

Chinese liquor:

[performance] acrid in the mouth, sweet, warm in nature.Ability and blood are promoted blood circulation, the cold relieving the mind invigorating, and a surname leads the medicine gesture.In addition, but rice wine replenishing vital QI with drugs of warm nature taste again, and rice wine, yellow wine have certain benefiting action.

[purposes] is used for arthromyodynia, and passages through which vital energy circulates is unfavorable, limbs pain, contracture; The thoracic obstruction, the breast sun is not declared, chest dull pain, or chest pain radiating to the back; Blood stasis or yin-cold excess disease; The tired Mental fatigue of tired back body, limb aching pain.

[usage] directly drinks or the temperature drink.With medicine with frying in shallow oil or converting clothes with medicinal liquid, take some ball, the medicament that looses, some food of infuse, medicine.

The chemical constituent of wine is an ethanol, generally contains the fusel and the Ester of trace, and the concentration of edible distillate spirit is below 60 degree (promptly 60%), and it is medical alcohol that Chinese liquor purifies to 75% or more through fractional distillation, and being purified to more than 99.5% is dehydrated alcohol.Wine is that raw material forms through fermented soy with grain.China is the country of making wine the earliest; Before 2000, just invented brewing technology; And update and perfect; Developed into now and can produce various concentration, various odor type, the various beverage that contains wine, and be that to produce out concentration be medical alcohol and 99.99% dehydrated alcohol more than 95% for industrial, health care and scientific experimentation.Because wine is in vogue, crime rate sharply rises.Drinking lets the people benumb easily, thus the not clear-headed behavior that loses one's marbles.

Oleum Glycines:

[nature and flavor] suffering; Sweet; Temperature [return through] large intestine channel

[effect classification] moisturized medicine

[effect] loosening bowel to relieve constipation; The anthelmintic detoxifcation

[textual criticism] come from Compendium of Material Medica.

[section belongs to classification] pulse family

[curing mainly] helminth is blocked; Constipation; Scabies erythromycin:

" erythromycin is the representational antibiotics that is by the macrolide (macrolide) that streptomyces erythareus (Streptomyces erythreus) is produced.”?。Lauryl sulfate (erythromycin estolate) hyoscine that its ethyl succinate (erythromycin ethylsuccinate), propionic ester are still arranged in addition.

These article are macrolide antibiotics; Antimicrobial spectrum and penicillin are approximate; To gram positive bacteria, stronger inhibitory action is arranged like staphylococcus, micrococcus scarlatinae, viridans streptococci, streptococcus pneumoniae, streptococcus faecalis, Hemolytic streptococcus, clostridium, diphtheria corynebacterium, anthrax bacillus etc.To gram-negative bacteria, certain inhibitory action is also arranged like gonococcus, pylori, bordetella pertussis, Brucella, legionella, meningococcus and hemophilus influenza, bacteroid, part dysentery bacterium and escherichia coli etc.In addition, mycoplasma, actinomycetes, spirillum, rickettsia, chlamydia, slave's card bacterium, minority mycobacteria and ameba there is inhibitory action.Staphylococcus aureus is prone to drug resistance to these article.Characteristics are that penicillin is produced chemical sproof bacterial strain, and are responsive to these article.Mechanism of action mainly is to combine with the 50S subunit of ribosome, and the peptide for inhibiting acyltransferase influences the shifting process of ribosome, hinders the peptide chain growth, suppresses the synthetic of bacterioprotein, is antibacterial.

Be applicable to that neonatal conjunctivitis, infant pneumonia, genitourinary tract that mycoplasma pneumonia, chlamydia trachomatis cause infect that respiratory tract infection (comprising pneumonia), angina rheumatica, the Li Side bacterium that (comprising nongonococcai urethritis), l, diphtheria (auxiliary treatment) and diphtheriaphor, skin soft-tissue infection, pertussis, sensitive organism (hemophilus influenza, streptococcus pneumoniae, Hemolytic streptococcus, staphylococcus etc.) cause infects, the long-term prevention of rheumatic fever and endocarditic prevention, campylobacter jejuni enteritis, and gonorrhea, syphilis, acne etc.Be mainly used in penicillin-fast infection of staphylococcus aureus clinically and reach infection of staphylococcus aureus penicillin anaphylaxis.Also be used for the infection such as respiratory tract, Legionnaires Pneumonia, mycoplasma pneumonia, skin soft tissue due to Hemolytic streptococcus and the streptococcus pneumoniae, in addition, dialogue laryngopathy people, then evident in efficacy with these article and diphtheria antitoxin coupling.

Vitamin B:

Vitamin B (Vitamin B) is also made vitamin B, is the general name of some vitamin, and they usually come from identical food source, like yeast etc.Vitamin B once was considered to as vitamin C, have the organic compound of single structure; But it is one group of chemical compound that different structure is arranged in fact for the proof of research afterwards; So its member has had independently title; Like vitamin B1, and vitamin B becomes a general name, also is called as the assorted or compound crowd of vitamin B of vitamin B complex, vitamin B sometimes.Vitamin B all is a water soluble vitamins, and they are synergism, regulates metabolism, keeps the health of skin and muscle, promotes immune system and neural function, promotes cell growth and division (comprise promoting erythrocytic generation, the prevention anemia takes place).

Comprise B1.B2.B3.B5.B6 and H etc. with the closely-related vitamin B group of skin protection.Vitamin B1 is claimed thiamine again, can suppress cholinesterase activity, alleviates the scytitis reaction, and the effect of the seborrheic dermatitis of control, eczema, enhancement skin health is arranged.Be mainly derived from corn, fresh vegetables, fruit, Lac Bovis seu Bubali, egg yolk, lean meat, liver, yeast, furfur, Semen arachidis hypogaeae etc.Vitamin B2 is claimed riboflavin again, participates in the redox reaction of cell, and the metabolism of the synthetic and sugar of hemoglobin, protein, fat can help skin to resist the infringement of daylight, promotes cell regeneration.When being deficient in vitamin B2 in the body, skin is relatively more responsive to daylight, occurs solar dermatitis easily, and of a specified duration by the daylight solarization, face is rubescent itches, and around nose, has powder to occur.Be mainly derived from egg yolk, Lac Bovis seu Bubali, yeast, green vegetable, Testa oryzae, plumule, animal livers and kidney, Radix Dauci Sativae, brewer's yeast, fish, Fructus Citri tangerinae, Citrus chachiensis Hort., orange etc.Vitamin B3 is called nicotinic acid again, can suppress the formation of dermal melanin, prevents pachylosis.Cell that helps being hurt or skin restore.To keeping normal structure, especially skin, digestive tract, neural integrity have important function.Vitamin B6 and skin health have substantial connection, are the parts of a lot of enzymes and auxiliary enzymes molecular structure.Promote amino acid whose metabolism to keep skin health, can reduce capillary wall permeability and hyaluronidase activity, reduce allergy, inflammatory reaction, promote epithelial cell growth.Can be used for preventing and treating pachylosis, acne, daylight sunburn, antipruritic and sunlight is tanned, also can be used for preventing and treating seborrhea atopic dermatitis disease, general acne, dryness seborrheic dermatitis eczema and exfoliation property skin and change.Be mainly derived from liver, egg yolk, corn, plumule, beans, Lac Bovis seu Bubali, Fish, meat, vegetable.Biotin is claimed biotin (biotin) again, can promote skin metabolism, improves pachylosis, prevents alopecia, seborrheic dermatitis, polymorphous acne (acne) etc.Be present in the foods such as liver, egg yolk, milk, yeast.

The specific embodiment:

Embodiment 1, prescription:

Cortex Meliae 40g, mentha leave 40g, Fructus Quisqualis 40g, Semen Torreyae 40g, Semen Cucurbitae 40g, Semen Arecae 40g, Cortex Hibisci 30g, Camphora 30g, Folium Hibisci Rosae-Sinensis 30g, Colophonium 30g, Folium Indigoferae teysmannii 30g, Herba Peristrophes 30g, Herba Violae 20g, Fructus Carpesii 20g, Herba Ophioglossi 20g, Folium Acori graminei 20g, Radix Sophorae Tonkinensis 20g, Borneolum Syntheticum 20g, Rhizoma Zingiberis Recens 10g, Bulbus Allii 10g, Chinese liquor 10g, Oleum Glycines 10g, erythromycin 10g, vitaminB10 g;

Method for preparing comprises:

A, Borneolum Syntheticum is dissolved in the Chinese liquor by formula proportion;

B, step 1 gained solution and Oleum Glycines, erythromycin, vitamin B are fully with must stock solution after water mixes subsequent use;

C, by formula proportion Cortex Meliae, mentha leave, Fructus Quisqualis, Semen Torreyae, Semen Cucurbitae, Semen Arecae, Cortex Hibisci, Camphora, Folium Hibisci Rosae-Sinensis, Colophonium, Folium Indigoferae teysmannii, Herba Peristrophes, Herba Violae, Fructus Carpesii, Herba Ophioglossi, Folium Acori graminei, Radix Sophorae Tonkinensis, Rhizoma Zingiberis Recens, Bulbus Allii are screened → weighing assorts → dries → after pulverizing; Put into and be equipped with that to contain 5 times of amount concentration be that 80% (V/V) Chinese liquor solution mix to stir, flood and adjust flow velocity after 24 hours; When the existing stock solution of potching liquid 3/4 the time stop percolation, press residue, it is for use to get percolation;

D, step 2 mixed the subsequent use stock solution in back mix, stir with step 3 percolate, then under 0-10 ℃ of temperature with ultrasound wave homogenize 10-30 minute, sterilize, packing is finished product.

Usage and dosage: get medical Cotton Gossypii or cotton during use, be equal on the area average price at impaired skin and smear evenly, every day six times, cure next day.

Embodiment 2, prescription:

Cortex Meliae 42g, mentha leave 42g, Fructus Quisqualis 42g, Semen Torreyae 42g, Semen Cucurbitae 42g, Semen Arecae 42g, Cortex Hibisci 32g, Camphora 32g, Folium Hibisci Rosae-Sinensis 32g, Colophonium 32g, Folium Indigoferae teysmannii 32g, Herba Peristrophes 32g, Herba Violae 22g, Fructus Carpesii 22g, Herba Ophioglossi 22g, Folium Acori graminei 22g, Radix Sophorae Tonkinensis 22g, Borneolum Syntheticum 22g, Rhizoma Zingiberis Recens 12g, Bulbus Allii 12g, Chinese liquor 12g, Oleum Glycines 12g, erythromycin 12g, vitamin B12 g;

Method for preparing, usage and dosage are identical with embodiment 1.

Embodiment 3, prescription:

Cortex Meliae 45g, mentha leave 45g, Fructus Quisqualis 45g, Semen Torreyae 45g, Semen Cucurbitae 45g, Semen Arecae 45g, Cortex Hibisci 35g, Camphora 35g, Folium Hibisci Rosae-Sinensis 35g, Colophonium 35g, Folium Indigoferae teysmannii 35g, Herba Peristrophes 35g, Herba Violae 25g, Fructus Carpesii 25g, Herba Ophioglossi 25g, Folium Acori graminei 25g, Radix Sophorae Tonkinensis 25g, Borneolum Syntheticum 25g, Rhizoma Zingiberis Recens 15g, Bulbus Allii 15g, Chinese liquor 15g, Oleum Glycines 15g, erythromycin 15g, VITAMIN B15 g;

Method for preparing, usage and dosage are identical with embodiment 1.

Embodiment 4, prescription:

Cortex Meliae 48g, mentha leave 48g, Fructus Quisqualis 48g, Semen Torreyae 48g, Semen Cucurbitae 48g, Semen Arecae 48g, Cortex Hibisci 38g, Camphora 38g, Folium Hibisci Rosae-Sinensis 38g, Colophonium 38g, Folium Indigoferae teysmannii 38g, Herba Peristrophes 38g, Herba Violae 28g, Fructus Carpesii 28g, Herba Ophioglossi 28g, Folium Acori graminei 28g, Radix Sophorae Tonkinensis 28g, Borneolum Syntheticum 28g, Rhizoma Zingiberis Recens 18g, Bulbus Allii 18g, Chinese liquor 18g, Oleum Glycines 18g, erythromycin 18g, vitamin B1 8g;

Method for preparing, usage and dosage are identical with embodiment 1.

Embodiment 5, prescription:

Cortex Meliae 50g, mentha leave 50g, Fructus Quisqualis 50g, Semen Torreyae 50g, Semen Cucurbitae 50g, Semen Arecae 50g, Cortex Hibisci 40g, Camphora 40g, Folium Hibisci Rosae-Sinensis 40g, Colophonium 40g, Folium Indigoferae teysmannii 40g, Herba Peristrophes 40g, Herba Violae 30g, Fructus Carpesii 30g, Herba Ophioglossi 30g, Folium Acori graminei 30g, Radix Sophorae Tonkinensis 30g, Borneolum Syntheticum 30g, Rhizoma Zingiberis Recens 20g, Bulbus Allii 20g, Chinese liquor 20g, Oleum Glycines 20g, erythromycin 20g, vitamin B2 0g;

Method for preparing, usage and dosage are identical with embodiment 1.

Result of the test:

To the oidiomycetic fungistatic effect of white

Note: The positive control group, the average number of colonies and scope of the 7.50 ×

? (6.10 ×

~ 8.70 × ) cfu / ml negative control bacterial growth.

Fungistatic effect to staphylococcus aureus

Note: The positive control group, the average number of colonies and scope of the 6.32 ×

? (4.85 ×

~ 7.15 ×

) cfu / ml negative control bacterial growth.

Conclusion (of pressure testing):

Conclusion 1:The present invention is directed to and cause behind the mosquito bite: the body surface disease that pathogenic microorganism and other reason cause, staphylococcus aureus, Candida albicans are acted on 2min, 5min, 10min, 20min respectively, its average bacteriostasis rate is 100%.

Conclusion 2:

2.1, clinical observation of the present invention 500 routine body surface diseases, recovery from illness is 67%, effective percentage 95%.

2.2, criterion of therapeutical effect: after the medication time in a few days disease disappear and be recovery from illness; Disease disappears for effective in 5 minutes;

Disease can not disappear for invalid in 3 days.

Claims (1)

1. a compound spirit of preventing and treating the domestic animal mosquito bite is characterized in that, is to be processed by following weight portion raw material:

Cortex Meliae 40-50 part; Mentha leave 40-50 part; Fructus Quisqualis 40-50 part; Semen Torreyae 40-50 part; Semen Cucurbitae 40-50 part; Semen Arecae 40-50 part; Cortex Hibisci 30-40 part; Camphora 30-40 part; Folium Hibisci Rosae-Sinensis 30-40 part; Colophonium 30-40 part; Folium Indigoferae teysmannii 30-40 part; Herba Peristrophes 30-40 part; Herba Violae 20-30 part; Fructus Carpesii 20-30 part; Herba Ophioglossi 20-30 part; Folium Acori graminei 20-30 part; Radix Sophorae Tonkinensis 20-30 part; Borneolum Syntheticum 20-30 part; Rhizoma Zingiberis Recens 10-20 part; Bulbus Allii 10-20 part; Chinese liquor 10-20 part; Oleum Glycines 10-20 part; Erythromycin 10-20 part; VitaminB10-20 part;

A kind of compound spirit of preventing and treating the domestic animal mosquito bite is characterized in that, is to be processed by following weight portion raw material:

Cortex Meliae 42-48 part; Mentha leave 42-48 part; Fructus Quisqualis 42-48 part; Semen Torreyae 42-48 part; Semen Cucurbitae 42-48 part; Semen Arecae 42-48 part; Cortex Hibisci 32-38 part; Camphora 32-38 part; Folium Hibisci Rosae-Sinensis 32-38 part; Colophonium 32-38 part; Folium Indigoferae teysmannii 32-38 part; Herba Peristrophes 32-38 part; Herba Violae 22-28 part; Fructus Carpesii 22-28 part; Herba Ophioglossi 22-28 part; Folium Acori graminei 22-28 part; Radix Sophorae Tonkinensis 22-28 part; Borneolum Syntheticum 22-28 part; Rhizoma Zingiberis Recens 12-18 part; Bulbus Allii 12-18 part; Chinese liquor 12-18 part; Oleum Glycines 12-18 part; Erythromycin 12-18 part; Vitamin B12-18 part;

A kind of compound spirit of preventing and treating the domestic animal mosquito bite is characterized in that, is to be processed by following weight portion raw material:

45 parts of Cortex Meliaees, 45 parts of mentha leavves, 45 parts of Fructus Quisqualis, 45 parts of Semen Torreyaes, 45 parts of Semen Cucurbitaes, 45 parts of Semen Arecaes, 35 parts of Cortex Hibiscis, 35 parts of Camphoras, 35 parts of Folium Hibisci Rosae-Sinensiss, 35 parts of Colophonium, 35 parts of Folium Indigoferae teysmanniis, 35 parts of Herba Peristrophess, 25 parts of Herba Violaes, 25 parts of Fructus Carpesiis, 25 parts of Herba Ophioglossis, 25 parts of Folium Acori gramineis, 25 parts of Radix Sophorae Tonkinensiss, 25 parts of Borneolum Syntheticums, 15 parts in Rhizoma Zingiberis Recens, 15 parts in Bulbus Allii, 15 parts of Chinese liquor, 15 parts in Oleum Glycines, 15 parts in erythromycin, VITAMIN B15 part;

A kind of compound spirit of preventing and treating the domestic animal mosquito bite is characterized in that method for preparing comprises:

A, Borneolum Syntheticum is dissolved in the Chinese liquor by formula proportion;

B, step 1 gained solution and Oleum Glycines, erythromycin, vitamin B are fully with must stock solution after water mixes subsequent use;

C, by formula proportion Cortex Meliae, mentha leave, Fructus Quisqualis, Semen Torreyae, Semen Cucurbitae, Semen Arecae, Cortex Hibisci, Camphora, Folium Hibisci Rosae-Sinensis, Colophonium, Folium Indigoferae teysmannii, Herba Peristrophes, Herba Violae, Fructus Carpesii, Herba Ophioglossi, Folium Acori graminei, Radix Sophorae Tonkinensis, Rhizoma Zingiberis Recens, Bulbus Allii are screened → weighing assorts → dries → after pulverizing; Put into and be equipped with that to contain 5 times of amount concentration be that 80% (V/V) Chinese liquor solution mix to stir, flood and adjust flow velocity after 24 hours; When the existing stock solution of potching liquid 3/4 the time stop percolation, press residue, it is for use to get percolation;

D, step 2 mixed the subsequent use stock solution in back mix, stir with step 3 percolate, then under 0-10 ℃ of temperature with ultrasound wave homogenize 10-30 minute, sterilize, packing is finished product.