CN104381713A - Compound feeds for sheep and preparation method for compound feeds - Google Patents

Abstract

The invention discloses compound feeds for sheep and a preparation method for the compound feeds. The feeds comprise the following raw materials: corns, bran, soybean meal, cottonseed meal, limestone, salt, sunflower cakes, yeast powder, green hay, calcium carbonate, corn straws, distilled grains, fish meal, dried carrots, shell powder and vitamin additives. The preparation method comprises a crushing step, a batching step, a granulation step and a drying step. The compound feeds and the preparation method have the beneficial effects that the compound feeds contain Chinese medicinal additives with the effects of removing blood stasis, stopping bleeding, dispersing water swelling, soothing the liver, relieving depression and invigorating spleen to promote digestion, so that the compound feeds have the advantages of better curative effects, no medicinal residues, low cost and the like; the Chinese medicinal additives are compounded and react with other feed raw materials, so that infectious necrotic hepatitis can be controlled, the nutritional requirements of sheep can be met, and the nutritional requirements of sheep suffering from infectious necrotic hepatitis can particularly be met.

Description

A kind of sheep mixed feed and preparation method thereof

Technical field

The present invention relates to beasts field of fodder, particularly a kind of sheep mixed feed and preparation method thereof.

Background technology

Sheep black disease has another name called infectious necrotic hepatitis, is the one acute height lethal toxaemia of sheep and goat.This disease betides Australia, New Zealand, France, Chile, Britain, the U.S., Germany; Also there is this sick existence in Asia.

Cause of disease and epidemiology: Nuo Weishi clostridium (Cl.novyi) and sheep braxy, sheep be sudden to be hit, the cause of disease of enterotoxemia is the same, belongs to Clostridium.This bacterium is Gram-positive escherichia coli, and strictly anaerobic can form brood cell, not produce pod membrane.This bacterium is divided into A, B, C tri-type.A type bacterium can produce α, γ, ε, δ tetra-kinds of exotoxins; Type B bacterium produces ε, β, η, ζ, θ five kinds of exotoxins; C type bacterium does not produce exotoxin, and this kind of bacterium is relevant with myelitis, but without aetology meaning.This bacterium can make the sheep of more than 1 years old infect, and occurs at most with the sheep of 2 ~ 4 years old.Morbidity sheep mostly only is the fat sheep of eutrophy, and goat also can infect, and ox occasionally can infect.Be the most responsive with cavy in animal used as test, rabbit, mouse neurological susceptibility are lower.This disease mainly betides the popular low-lying humid area of Fasciola hepatica at spring and summer.

Clinical symptoms and cause of disease: this disease is extremely similar with sheep braxy, enterotoxemia etc. clinically.The course of disease is very rapid, and most situation has no ill and suddenly death occurs.The minority case course of disease is slightly long, can delay 1 ~ 2d, but not more than 3d's.Ill domestic animal falls group, does not eat, expiratory dyspnea, and body temperature about 41.5 DEG C is prostrate in lethargic sleep, and maintenance has no painfully to die suddenly in this state.Under sick sheep cadaver skin, vein is significantly congested, and its skin is furvous outward appearance (namely the name of black disease is come therefrom).The frequent oedema of subcutaneous tissue of chest.Serous cavity has liquid to ooze out, and is exposed to air and is easy to solidify, and liquid is often in yellow, but peritoneal fluid slightly color.Often hemorrhage under endocardium of left ventricle.Abomasum pyloric part and little enteremia and hemorrhage.The congested swelling of liver, can see from surface or touch one to multiple coagulation necrosis stove, the distinct of necrosis region, lark, not full circle shape, around the cherry hyperemia band of Chang Weiyi around, necrosis region diameter can reach 2 ~ 3cm, and tangent plane becomes semicircle.This necrosis change of sheep black disease liver is very feature, has very large diagnostic significance.

Diagnosis: sick sheep dead under the area that Fasciola hepatica is popular finds extremely anxious or lethargic state, cuts open inspection and sees special hepatic necrosis change, contribute to diagnosis.Bacteriology checking and toxin inspection can be done if desired.Toxin checks available Nagler's reaction.This method recall rate and specificity all higher.Its method is the filtrate by the ascites of animals died of illness or the precipitation supernatant of necrosis region suspensions of tissues or clarification, add 4, test tube, often prop up 0.5ml, A type Nuo Weishi clostridium antitoxic serum, Type B Nuo Weishi clostridium antitoxic serum and clostridieum welchii 6 antitoxic serum 0.25ml is added again respectively in 1st ~ 3 pipes, 4th pipe does not add with measuring physiological saline with antitoxic serum, in contrast.Mix, act on 30min under putting room temperature, then often pipe adds lecithin vitellin liquid 0.25ml, mixes 1 ~ 2h in rearmounted incubator, takes out observed result.If contrast produces opalescence layer, namely represent containing lecithinase in tested material, in 1st ~ 3 pipes this reaction suppress by the antitoxin of which kind of bacterium, namely prove that this lecithinase is produced by this kind of bacterium.

The clostridium property diseases such as sheep black disease, sheep braxy, sheep be sudden to be hit, sheep enterotoxemia due to the course of disease very brief, symptom is similar, not easily distinguishes mutually clinically, and meanwhile, this class disease also has similarity clinically with braxy, therefore, should notice that class disease is distinguished.

Doctor trained in Western medicine control sheep black disease is sick: prevent this disease to be first to control the infection of Fasciola hepatica.Specific immunity can carry out immunization campaign with black disease, fast epidemic disease Combined vaccine or anaerobic bacteria seven dry powder seedling.When there is this disease, flock of sheep should be moved and herd in high and dry area.Can treat with anti-Nuo Weishi clostridium serum (every milliliter containing 7500IU) sick sheep.But the sick therapeutic scheme of doctor trained in Western medicine control sheep black disease is single, and medicine is limited, rapidly, the wayward state of an illness, if can not symptom management in time, range of infection expansion, then can cause the mortality of disease sheep, cause huge economic loss to culturist in this sick morbidity.

But traditional Chinese medicine prevention sheep black disease disease have accumulated abundant clinical experience, has abundant theoretical foundation, utilize Traditional Chinese medical theory, diagnosis and treatment is carried out on the basis of Overall View, and targeting is comparatively strong, and, adopt natural Chinese traditional medicines material, cheapness, while control sheep black disease, can improve sheep immunity, strengthen the ability etc. of its defence disease and evil, can marketing be carried out.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of sheep mixed feed and preparation method thereof, containing having removing blood stasis and hemostasis, the water conservancy that disappears swells, the Chinese medicine additive of effect of soothing liver-qi stagnation, reinforcing spleen to promote digestion, the present invention has and utilizes Traditional Chinese medical theory, diagnosis and treatment is carried out on the basis of Overall View, and targeting is comparatively strong, and drug effect can be gone directly focus, effective symptom management, evident in efficacy, illness rate, the death rate can be reduced, improve cure rate, survival rate etc.Further, adopt natural Chinese traditional medicines material, cheap, safe and effective, drug residue free, while control sheep black disease, can improve the appetite of sheep, meet its growing nutrient demand.

For solving the problems of the technologies described above, the invention provides a kind of sheep mixed feed, wherein, described mixed feed comprises following raw material: corn, wheat bran, dregs of beans, cotton dregs, stone flour, salt, sunflower cake, dusty yeast, green hay, calcium carbonate, maize straw, vinasse, fish meal, dried carrot and oyster shell whiting.

In described feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 20-28 weight portion, dregs of beans 6-8 weight portion, cotton dregs 3-6 weight portion, stone flour 0.1-0.6 weight portion, salt 0.2-0.8 weight portion, sunflower cake 2-4 weight portion, dusty yeast 1-2 weight portion, green hay 10-15 weight portion, calcium carbonate 0.2-0.4 weight portion, maize straw 25-30 weight portion, vinasse 1-2 weight portion, fish meal 2-3 weight portion, dried carrot 3-6 weight portion and oyster shell whiting 1-2 weight portion.

Described feed also comprises Chinese medicine additive, and in described feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 20-28 weight portion, dregs of beans 6-8 weight portion, cotton dregs 3-6 weight portion, stone flour 0.1-0.6 weight portion, salt 0.2-0.8 weight portion, sunflower cake 2-4 weight portion, dusty yeast 1-2 weight portion, green hay 10-15 weight portion, calcium carbonate 0.2-0.4 weight portion, maize straw 25-30 weight portion, vinasse 1-2 weight portion, fish meal 2-3 weight portion, dried carrot 3-6 weight portion, oyster shell whiting 1-2 weight portion and Chinese medicine additive 6-8 weight portion.

In described feed, the parts by weight of each raw material are: corn 32 weight portion, wheat bran 24 weight portion, dregs of beans 6 weight portion, cotton dregs 4 weight portion, stone flour 0.3 weight portion, salt 0.3 weight portion, sunflower cake 3 weight portion, dusty yeast 1 weight portion, green hay 10 weight portion, calcium carbonate 0.2 weight portion, maize straw 25 weight portion, vinasse 1 weight portion, fish meal 2 weight portion, dried carrot 3 weight portion, oyster shell whiting 1 weight portion and Chinese medicine additive 7 weight portion.

Described Chinese medicine additive comprises following raw medicinal material: Paris polyphylla, adder-wort, field pennycress, wolf's milk, climbing groundsel, moutan bark, the radix paeoniae rubrathe, fevervine, the fruit of Rangoon creeper, betel nut, pumpkin seeds, field thistle, sophora flower, cogongrass rhizome, sheep hoof, Japanses beauty-berry, Artemisia anomala, madder, dalbergia wood, lily, the Radix Astragali, adenophora tetraphylla, Tu Gupi, Epipremnum pinnatunz, Semen Herpetospermi, Phytolacca acinosa and Radix Betae.

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Paris polyphylla 4-6 weight portion, adder-wort 10-20 weight portion, field pennycress 10-18 weight portion, wolf's milk 12-22 weight portion, climbing groundsel 15-25 weight portion, moutan bark 10-23 weight portion, radix paeoniae rubrathe 10-20 weight portion, fevervine 12-25 weight portion, fruit of Rangoon creeper 13-36 weight portion, betel nut 12-29 weight portion, pumpkin seeds 14-30 weight portion, field thistle 15-28 weight portion, sophora flower 15-31 weight portion, cogongrass rhizome 10-24 weight portion, sheep hoof 10-20 weight portion, Japanses beauty-berry 12-27 weight portion, Artemisia anomala 10-20 weight portion, madder 12-24 weight portion, dalbergia wood 10-15 weight portion, lily 15-28 weight portion, Radix Astragali 10-24 weight portion, adenophora tetraphylla 12-24 weight portion, soil bone skin 10-20 weight portion, Epipremnum pinnatunz 10-18 weight portion, Semen Herpetospermi 12-20 weight portion, Phytolacca acinosa 4-7 weight portion is with Radix Betae 4-6 weight portion.

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Paris polyphylla 4 weight portion, adder-wort 16 weight portion, field pennycress 18 weight portion, wolf's milk 22 weight portion, climbing groundsel 25 weight portion, moutan bark 23 weight portion, the radix paeoniae rubrathe 20 weight portion, fevervine 25 weight portion, the fruit of Rangoon creeper 26 weight portion, betel nut 19 weight portion, pumpkin seeds 20 weight portion, field thistle 18 weight portion, sophora flower 21 weight portion, cogongrass rhizome 18 weight portion, sheep hoof 15 weight portion, Japanses beauty-berry 17 weight portion, Artemisia anomala 18 weight portion, madder 24 weight portion, dalbergia wood 15 weight portion, lily 18 weight portion, the Radix Astragali 17 weight portion, adenophora tetraphylla 22 weight portion, soil bone skin 20 weight portion, Epipremnum pinnatunz 18 weight portion, Semen Herpetospermi 20 weight portion, Phytolacca acinosa 5 weight portion is with Radix Betae 6 weight portion.

The preparation method of described Chinese medicine additive comprises the following steps:

Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 3 ~ 5 times, mixture is the ethanol of 84% ~ 95%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.07 ~ 0.09Mpa, relative density is the lotion of 1.05 ~ 1.10, spraying dry, the EAT 150 ~ 165 DEG C of spray dryer, leaving air temp 70 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;

Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.1 ~ 0.3 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes particle, in 45 ~ 50 DEG C of dryings, obtains granule.

For solving the problems of the technologies described above, present invention also offers a kind of preparation method of sheep mixed feed, wherein, described preparation method comprises the following steps:

(1) pulverising step: take corn, wheat bran, dregs of beans, cotton dregs, sunflower cake, green hay, maize straw, vinasse, dried carrot and Chinese medicine additive by ratio of weight and the number of copies, drops into pulverizer and carries out Crushing of Ultrafine, crosses 3.5mm sieve and obtain fine powder after pulverizing;

(2) batching step: take stone flour, salt, dusty yeast, calcium carbonate, fish meal, oyster shell whiting and vitamine supplement according to ratio of weight and number, pulverizes with step (1) fine powder obtained and mixes, and drop into mixer, mix, incorporation time is 50-60s;

(3) granulation step: mixture is dropped into the water that granulator adds mixture quality 2-3 times amount, granulate, grain temperature is 70-85 DEG C, makes its gelatinization degree reach more than 94%.

(4) drying steps: the feed granules that step (3) obtains is carried out air-dry drying when temperature is 50 DEG C-60 DEG C, obtains feed packing.

The invention has the beneficial effects as follows: the present invention contain there is removing blood stasis and hemostasis, the water conservancy that disappears swells, the Chinese medicine additive of effect of soothing liver-qi stagnation, reinforcing spleen to promote digestion, the present invention has and utilizes Traditional Chinese medical theory, diagnosis and treatment is carried out on the basis of Overall View, targeting is stronger, drug effect can be gone directly focus, and effective symptom management is evident in efficacy, illness rate, the death rate can be reduced, improve cure rate, survival rate etc.Further, adopt natural Chinese traditional medicines material, cheap, safe and effective, drug residue free, while control sheep black disease, can improve the appetite of sheep, meet its growing nutrient demand.

Detailed description of the invention

Chinese veterinarian's theory is thought, sheep black disease to be damaged and insufficiency of the spleen due to the liver that causes of diseases caused by external factors virus, removing blood stasis and hemostasis answered in treatment, the water conservancy that disappears is swollen, soothing liver-qi stagnation, reinforcing spleen to promote digestion, enhancing sheep Abwehrkraft des Koepers.

According to above-mentioned theory and principle, the invention provides a kind of like this Chinese medicine composition being used for the treatment of sheep black disease, it comprises: Paris polyphylla, adder-wort, field pennycress, wolf's milk, climbing groundsel, moutan bark, the radix paeoniae rubrathe, fevervine, the fruit of Rangoon creeper, betel nut, pumpkin seeds, field thistle, sophora flower, cogongrass rhizome, sheep hoof, Japanses beauty-berry, Artemisia anomala, madder, dalbergia wood, lily, the Radix Astragali, adenophora tetraphylla, Tu Gupi, Epipremnum pinnatunz, Semen Herpetospermi, Phytolacca acinosa and Jun Da.

Wherein, Paris polyphylla, the adder-wort water conservancy that disappears swells; Field pennycress, wolf's milk, climbing groundsel, moutan bark, the radix paeoniae rubrathe, Tu Gupi, Epipremnum pinnatunz and Semen Herpetospermi clearing heat and cooling blood, reinforcing spleen to promote digestion; Fevervine, the fruit of Rangoon creeper, betel nut, pumpkin seeds, Phytolacca acinosa He Radix Betae desinsection; Field thistle, sophora flower, cogongrass rhizome, sheep hoof, Japanses beauty-berry cooling blood and hemostasis; Artemisia anomala, madder, marmor serpentinatum, dalbergia wood removing blood stasis and hemostasis; Lily, the Radix Astragali, adenophora tetraphylla tonifying QI to produce body fluid.

Now each taste Chinese medicine is described below:

Paris polyphylla: have another name called paris polyphylla.Bitter, cold; Enter Liver Channel.There is the merit of clearing heat and detoxicating, cool liver arresting convulsion, be applicable to multiple pathopyretic ulcer, abscess of throat, mumps, venomous snake bite, frightened epilepsy, unconsciousness due to high fever etc.Pharmacological research shows, this product is to the antibacterial action of the various bacteria such as enteric bacilli, pyococcus, and infected by influenza has inhibitory action, and has certain relievining asthma, antitussive action, but without phlegm-dispelling functions.Therefore, during flu pharyngalgia, eat a little flea and to stop or flea stops congee, can be clearing heat and detoxicating, eliminating stasis to subdue swelling, has obvious curative effects to abscess of throat.

Adder-wort: bitter, cool; Return lung, liver, large intestine channel." modern Practical Chinese medicinal ": " take orally and control dysentery characterized by blood in the stool; Containing gargling the astringent making stomatitis; Hemorrhoid and early stage of pyogenic infection of skin are controlled in external application." " Chinese medicinal herbal ": " is clearing heat and detoxicating, mass dissipating and swelling eliminating.Control pyreticosis and shy epilepsy, tetany, lockjaw, carbuncle swells scrofula, snake bite and insect sting." heat-clearing is relieving convulsion, the wet detumescence of reason.Control that pyreticosis is frightened jerks, lockjaw, dysentery characterized by blood in the stool, carbuncle swells, scrofula.Adder-wort is oozed adder-wort and to filter clean No. 1 of the hemostasis that liquid and gelatin etc. make, and all has certain haemostatic effect for dog and the various hemostasis experiment (femoral artery cuts off, liver clip, and splenectomy etc. are hemorrhage) of sheep.All antibacterial action is had in vitro to staphylococcus aureus, Pseudomonas aeruginosa, hay bacillus, Escherichia coli etc.

Field pennycress: taste is pungent, bitter, is slightly cold; Return liver, stomach, large intestine channel." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " cool blood-head, cold stomach are sent out in tripe abdomen all long-pending, diuresis.Compendium of Material Medica: " control blood and drench hemorrhoid complicated by anal fistula." Tang Materia Medica: " Patrinia scaniosaefolia, does not go out shortcut, and between Duo Shenggang ridge, leaf is like water Liang and common vetch rank, and grow thickly, brightly yellowish, root purple makes old dark reddish brown; Its leaf different Bu Si pig Xian also." function is clearing heat and detoxicating, cool blood, the carbuncle that disappears apocenosis, stasis-dispelling and pain-killing, for acute appendicitis, the high heat of lung carbuncle, coughs vomiting of pus and blood, hot carbuncle malignant boil, and sore furuncle pain is swollen, chest abdomen pain, appendicitis, enteritis, dysentery, postpartum abdominal pain, dysmenorrhoea.

Wolf's milk: be the wolf's milk of euphorbia plant, is a kind of Chinese medicine, gathers at summer, Qiu Erji, and removing impurity, dries." book on Chinese herbal medicine converges and says ": " cooling blood to dissipate stasis, removing toxic substances stops the medicine of dysentery also.Kind through-flow blood vessels, specially clear up carbuncle.All blood is sick and because of hot institute envoy, suitable with it.If non-blood-head is disease, and the thin weak person of stomach Qi, again when consideration row." Compendium of Material Medica: " main carbuncle is swollen dislikes sore, and it is hemorrhage that Jin Ren flutters damage, bloody flux, lower blood, metrorrhagia, and the blood that can fall apart stops blooding, diuresis." can be clearing heat and detoxicating, dampness removing removing jaundice, promoting blood circulation and hemostasis.Main dysentery, have loose bowels, jaundice; Hemoptysis; Spit blood; Hematuria; Have blood in stool; Uterine bleeding; Agalactia; Treating swelling and pain by traumatic injury and pathopyretic ulcer etc.Blood-head spit blood, bleeding from five sense organs or subcutaneous tissue person, can with radix rehmanniae recen, the same use of moutan bark, to increase the merit of cooling blood and hemostasis.Jaundice with damp-heat pathogen, difficult urination person, can be alone, or with the compatibility such as oriental wormwood, cape jasmine, with heat-clearing and dampness-resolving, also can be used for ulcer dislike sore, injuries from falls as well eczema ulcer, burn and scald and all cards of venomous snake bite, clinical multiplex fresh goods mashes external application.

Climbing groundsel: cold in nature, bitter.Supplement to the Herbal: " main epidemic disease gas, knot is yellow, malaria miasma, and cup poison, boils telling down of clothes, also smash the place of biting such as deposited sore, worm snake dog." " detailed outline is picked up any lost article from the road ": " improving eyesight goes star to hinder.Decoct soup bath sore.Dog stings mixes pollen with a thousand li cream and pastes it.Treating snakebite." heat-clearing, removing toxic substances, desinsection, improving eyesight, controls various acute inflammatory disease, wind fire cute conjunctivitis, order screen, typhoid fever; bacillary dysentery, lobar pneumonia, tonsillitis, enteritis, jaundice, influenza, toxaemia; septicemia, and carbuncle swells furuncle poison, dry wet tinea sore, and erysipelas, eczema, scalds, trichomonas vaginitis.For anemopyretic cold, red eye, swell pain, dysentery, skin eczema sore furuncle.Climbing groundsel has broad-spectrum antibiotic effect, has very strong inhibitory action to icterohemorrhagic form Leptospira.

Moutan bark: bitter, pungent, cold nature, enters the heart, liver, kidney channel." herbal classic ": " main fever and chills, apoplexy Chi Zong, convulsion, frightened epilepsy perverse trend, except the hard hemostasis of disease stays house stomach, five viscera settling, treat carbuncle sore." " Japan hanako materia medica ": " except perverse trend, happy look, clearance natural fibre line of meat blood vessels, apocenosis, logical menstruation, disappears and flutters damage hemostasis, continuous muscles and bones, and except wandering arthritis, fall tire lower eyelid, postpartum all cold and hot vim and vigour."。Compendium of Material Medica: " nourishing Yin and falling fire, separate spot poison, throat, diuresis stasis.Descendant specially controls fire mutually with yellow tiller, does not know that the merit of the root bark of tree peony more wins also.Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it." there is the effect of clearing heat and cooling blood, promoting blood circulation to remove blood stasis, be mainly used in treatment warm heat disease heat invading xuefen, send out spot, tell nosebleed, pyreticosis later stage hot Fu Yin divides heating, deficiency of Yin osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhoea, carbuncle sore tumefacting virus, falls and flutter the card such as the pain of injury, beriberoid pyretic arthralgia.Be apt to purify the blood, and invigorate blood circulation, thus have effect of cool the blood dissipate blood stasis, make blood flow freely and not stay the stasis of blood, the absurd clearly and not row of blood-head.Therefore to diseases such as intense heat in the blood, liver kidney hyperactivity of fire and stagnation of blood stasis, all rely on as key medicine.Moutan bark can increase CF to the anesthetized dog heart, reduces cardiac output, reduces the effect of left room work done.The mouse heating that Paeonol oral disposition typhoid fever, paratyphoid vaccine cause has refrigeration function, and reduces normal mouse body temperature.

The radix paeoniae rubrathe: nature and flavor is bitter, cold; Return Liver Channel." herbal classic ": " main perverse trend stomachache, except blood-arthralgia, broken hard long-pending, fever and chills hernia lump in the abdomen, pain relieving, diuresis, beneficial gas." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " rush down spleen fire, sending down abnormally ascending, promoting circulation of blood, the broken stasis of blood, loose clot, only stomachache, moves back blood-head, attacks carbuncle sore, control scabies leprosy." " property of medicine opinion ": " control lung perverse trend, Fu Zhong Xu pain, vim and vigour are gathered, and logical a surname's internal organs gather around gas, control evil pain sepsis, and disease bone heat time main, strong the five internal organs, kidney tonifying gas, controls trusted subordinate's heavily fortified point swollen, and married woman's blood closes obstructed, and disappear hemostasis, can lose purulence." stasis of blood can be gone, pain relieving, cool blood, detumescence.Can be used for controlling the stasis of blood stagnant through closing, hernia lump in the abdomen is gathered, stomachache, hypochondriac pain, bleeding from five sense organs or subcutaneous tissue, bloody flux, discharging fresh blood stool, hot eyes, and carbuncle swells.For warm heat disease, heat enters that ying blood, heating, tongue are deep red, body sends out macula, and blood-heat bleeding etc., also can be used for through closing, traumatic injury, the stagnation of QI-blood cards such as sore and toxic.

Fevervine: property is put down, sweet, the micro-hardship of taste." the sward property of medicine is standby to be wanted ": " its head controls new internal injury, and pot is carnivorous, and qi-restoratives kidney-nourishing, except fire is enriched blood; Wash sore pain relieving, the loose poison of the heat that disappears.Its leaf beats rice with confectionery, only dysentery." " Illustrated Book on Plants ": " be wash, removing toxic substances, removes wind, heat-clearing, loose cold.Apply nameless sores or boils, and mend muscles and bones." expelling wind and activating blood flow, analgesic antidotal, promoting digestion, dehumidifying detumescence.Treatment of rheumatalgia pain, diarrhoea dysentery, dirty abdomen pain, deficiency of vital energy edema, dizzy food is few, hepatosplenomegaly, scrofula, acute appendicitis, nameless sores or boils, traumatic injury.Fevervine TA lumbar injection can suppress mouse spontaneous activity, extends yellow Jackets lengths of one's sleep, has certain sedation.Fevervine TA can suppress myenteron to shrink, and the myenteron contracture caused by energy antagonism acetylcholine.Fevervine decoction has inhibitory action to S. aureus in vitro and Fu Shigella flexneri, and medicinal extract also has bacteriostasis to staphylococcus aureus and streptococcus pneumonia.

The fruit of Rangoon creeper: taste is sweet, warm in nature; Return spleen, stomach, large intestine channel.Compendium of Material Medica: " mostly all insecticides are toil, only make monarch, Chinese torreyanut, sweet and desinsection, and also one is also different.All children's adult have parasitosis, and approaching daybreak is food fruit of Rangoon creeper benevolence number piece on an empty stomach, or decoct soup with shell and swallow, and next day, worm was all dead and go out also.Or the raw seven stewing foods of cloud seven are also good.The sweet temperature of this thing taste, can desinsection, again beneficial taste, so can hold back abnormal heat and antidiarrheal dysentery." there is anti parasitic and Antifungi about.The mouse enterobiasis of fruit of Rangoon creeper's pulvis to natural infection has certain drives pinworm effect.Toxicity is little, and semifinished product (26.6g/kg) is oral to dog, except generation vomiting, hiccup, there is no other poisoning symptoms.

Bin youth: bitter, pungent, warm in nature.Return stomach, large intestine channel.Have desinsection, broken long-pending, sending down abnormally ascending is capable stagnant, and row aquation wets.Effect.Cure mainly the paddy that disappears to relieve oedema or abdominal distension through diuresis or purgation, kill enteron aisle volt corpse, pinworm; Except moisture, get round by bribery, sharp nine orifices, relieving restlessness, caking in broken abdomen; Also can control beriberi, oedema, pectoralgia, dysentery, abdominal distension is suffered from abdominal pain, stool and urine is unfavorable, mental disorder breathes heavily urgency, treat pernicious malaria, resist communicable subtropical diseases.Compendium of Material Medica: " semen arecae goes out ridge table, the southern regions of the Yunnan Province, i.e. flat the and puckery person of the large shape of a kind of abdomen in betel nut, and not like the good ear of the betel nut long taste of point, so-called pig betel nut person is.Cover the different of also local products, moderns very do not distinguish." by Liu Xun " ridge table record " cloud, hand over, wide survivor, betel nut on non-oceangoing ship, all semen arecae also, know in that and exhale as betel nut; delicate and old, adopt and eat it in fact, stay rattan, watt room ash with food to hold up, with communicable subtropical diseases of dispelling; receive its skin and be used as medicine, black outside skin, intracutaneous all muscle silk as coconut skin." Yunnan note " cloud again, large abdomen betel nut every has three, 200, cuts open it time blue or green, rolls up and eats it, namely subtract astringent taste with a slice betel and clam meal.See this one to say, then semen arecae and betel nut can be general, but the slightly bad ear of force rate betel nut.

Pumpkin seeds: sweet, temperature.Pumpkin seeds be suitable for roundworm disease, enterobiasis, taeniasis, hookworm disease, fluke disease, diabetes, hypertrophy of the prostate and postpartum brothers' oedema and hypogalactia people eat.For insufficiency of the spleen malnutrition, become thin weak; Edema due to deficiency of the spleen; Hypogalactia after delivery; Pertussis, cough dry throat; Tapeworm, roundworm and snail fever.The Scientific Articles that American Studies personnel once delivered also is pointed out to adhere to that eating pumpkin seeds just can treat hypertrophy of the prostate every day, and make second phase glucose recovery to the initial stage, obviously improve the third phase state of an illness, because the active component among pumpkin seeds can eliminate the swelling at prostate initial stage, also has the effect of prevention prostate cancer simultaneously.

Field thistle: sweet, bitter, cold.The thoughts of returning home, Liver Channel." classifying herbal ": " control blood and drench distending pain, traumatic injury, redly to collapse, leukorrhea." function cooling blood and hemostasis, eliminating stasis to resolve swelling.For bleeding from five sense organs or subcutaneous tissue, spit blood, hematuria, has blood in stool, metrostaxis, traumatism and bleeding, carbuncle sore tumefacting virus.Obviously can raise the blood pressure of non-reserpinization rat after field thistle crystallization iv, boosting intensity exists obviously, and obviously weakens the boosting of reserpinization rat field thistle crystallization, and without dose-effect relationship, the similar cruel amine of this interaction property.Field thistle water decoction 0.075g/ml nutrient solution is to the rabbit aorta strip performance contraction of tool adrenergic a acceptor, and this effect can by a ARBs phentolamine institute antagonism.Field thistle is traditional Hemostatic of traditional herb medicine, has confirmed that it has anastalsis, and obtains active ingredient of stopping blooding.Field thistle hemostasis mainly through making local vasoconstriction, suppresses fibrinolytic and plays effect.

Sophora flower: bitter, cold nature; Return liver, lung, the heart, large intestine channel." Japan hanako materia medica ": " control five hemorrhoid, pained, eye is red, kills abdomen and hides worm and heat, control skin wind, and intestines diarrhea due to wind-evil blood, dysentery." " book on Chinese herbal medicine asks former ": " be cool blood key medicine.Control gastral cavilty soldier pain, kill roundworm." there is cooling blood and hemostasis, effect of clearing liver-fire; Main hematochezia; Blood under hemorrhoid; Bloody flux; Hematuria; Blood drenches; Uterine bleeding; Spit blood; Bleeding from five sense organs or subcutaneous tissue; The headache of liver heat; Red eye, swell pain; Carbuncle swells sore.For having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, spit blood, bleeding from five sense organs or subcutaneous tissue, the hot hot eyes of liver, has a headache dizzy.

Cogongrass rhizome: taste is sweet, cold in nature, enter lung, stomach, urinary bladder channel." Bencao Tujing ": " lalang grass rhizome, the present has it everywhere.Spring sprouts, and cloth ground is as pin, and the thatch pin called between custom, also can eat, very beneficial children's.Xia Sheng spends in vain, so fine, withered to the autumn, and its root, to pure white, also very sweet and refreshing, adopted root June and used." Compendium of Material Medica: " antiemetic is defeated in battle all blood, and typhoid fever hiccup, lung heat breathes heavily urgency, oedema, jaundice, relieving alcoholism." have the effect of cooling blood and hemostasis, reducing fever and causing diuresis, be mainly used in haematemesis, hemoptysis that lung stomach has accumulated heat, damp invasion of lower energizer pents up the hematuria of bladder, and pyreticosis polydipsia draws drink, gastropyretic vomiting, the cards such as jaundice with damp-heat pathogen.Cogongrass rhizome decoction and water logging agent gavage, and have diuresis to normal rabbits, administration 5-10 days, and diuresis is the most obvious.Cogongrass rhizome decoction has obvious inhibitory action to Fu Shi and sonne bacillus in vitro, but to will Hayes and the effect of easypro Shigella flexneri nothing.Coixol contained by cogongrass rhizome has inhibitory action to the contraction of skeletal muscle and metabolism.

Sheep hoof: bitter, cold in nature, the thoughts of returning home, liver, large intestine channel." Japan hanako materia medica ": " control tinea, kill all worm pyogenic infections, vinegar rubs subsides." effect clearing away heat and loosing the bowels, cooling blood and hemostasis, killing parasites to relieve itshing.Cure mainly constipation, hematemesis and epistaxis, hematochezia, hemorrhoid blood, uterine bleeding, mange, in vain bald, carbuncle pyogenic infections from tumour or sore, traumatic injury.Join cacumen biotae, cooling blood and hemostasis, the two mutual reinforcement between is use, and what treatment blood-head compeled the absurd row of blood goes out blood trouble.Join alum, removing toxic substances desinsection treats tinea, for carbuncle pyogenic infections from tumour or sore, and eczema scabies, psoriasis itch etc.Rumex root tincture has certain inhibitory action to multiple pathomycete in vitro.After rumex root (kind is not identified) decoction is concentrated, alcoholic extract has inhibitory action to acute lymphoblastic type leukaemia, Acute monocytic type leukaemia and Acute granulocytic leukemia patient haemocyte dehydrogenase.Similar to rheum officinale, low dose has convergence, has laxative effective in a large number.And the reflexive cholagogic of energy, also there is some anastalsis.

Japanses beauty-berry: pungent, bitter, flat.Return liver, spleen, stomach warp.Loose stasis of blood hemostasis, swelling and pain relieving.Leaf: for spitting blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, has blood in stool; External curing traumatism and bleeding.Root: treating swelling and pain by traumatic injury, treating rheumatic ostealgia.Supplement to the Herbal: " separate all poisonous substances, ulcer, larynx numbness, poison is swollen, lower impotence, and snake a poisonous snake mentioned in ancient books is bugbite, mad dog poison, and liquor clothes; Also liquor wash sore swell, the long skin of dehematize." " illustrated handbook planted by middle traditional Chinese medicines ": " hemorrhage to esophageal vein, intestine gastric ulcer is hemorrhage, nosebleed, and wound hinders, empsyxis and have tooth pulled out and hemorrhagely all have good effect." the careless effect having promotion blood clotting of Japanses beauty-berry, there is direct contraction and an anastalsis indirectly by intestinal tube contracture compressing stifled resistance blood vessel to enteron aisle blood vessel.Japanses beauty-berry grass all has inhibitory action in various degree to Escherichia coli, shigella flexneri, staphylococcus aureus, hemolytic streptococcus etc.Japanses beauty-berry can make bleeding time and reduced clotting time, and its hemostasis principle may be that it makes vessel retraction and platelet count is increased.

Artemisia anomala: bitter, temperature; Enter the heart, the spleen channel." Japan hanako materia medica ": " control pain in the chest and abdomen, lower air water be swollen, vim and vigour, logical married woman's passages through which vital energy circulates crux, only cholera watery diarrhea." " Kaibao Bencao ": " treats metal-inflicted wound, stops blooding as key medicine; Disease more than postpartum, lower blood, pain relieving." broken blood stimulates the menstrual flow, healing up sore and subduing swelling.Control through closing abdominal mass, chest and abdomen swelling and pain, postpartum blood stasis, traumatic injury, metal-inflicted wound is hemorrhage, Yong Du inflammation swell.The rat height serum glutamic pyruvic transminase (SGPT) that concentrated decocting liquid can make gossypol acetate cause obviously declines; Obvious choleretic effect is had to anesthetized dog and rat.Artemisia anomala TA and general flavone all can prevent and treat the rat height SGPT that gossypol acetate hepatic lesion causes, and are the active ingredient of Artemisia anomala decoction control gossypol hepatic lesion.

Madder: cold in nature, bitter, returns Liver Channel, " Bencao Jingshu ": " rubia, the key medicine of the cool blood of promoting circulation of blood.Main numbness and subcutaneous ulcer.Subcutaneous ulcer has five, this its for controlling, lid does not refer to jaundice of blood stasis, and not specially in damp and hot person yet.Numbness person's blood is sick, the soft heavily fortified point of promoting circulation of blood.Then numbness self-healing." " Japan hanako materia medica ": " and only profuse nasal bleeding, under band, postpartum anemic fainting, breast knot, menstruation is more than, intestines wind hemorrhoid complicated by anal fistula, apocenosis; Control sore furuncle, let out essence, hematuria, flutter damage hemostasis." effect: cooling blood and hemostasis; Promoting blood circulation and removing blood stasis, cure mainly blood-head spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, have blood in stool, uterine bleeding, through closing, postpartum stasis blocking stomachache, the card such as traumatic injury, arthralgia due to wind-dampness, jaundice, sore carbuncle, hemorrhoid are swollen.The antitussive action of madder is comparatively strong, eliminates the phlegm, relievings asthma and take second place, and have certain antiinflammation; After taking medicine, dry, the moist rale of lung and wheezing sound majority reduce or disappear.

Dalbergia wood: pungent, temperature.Return liver, the spleen channel.The promoting flow of qi and blood circulation, pain relieving, hemostasis.For epigastric pain, liver-depressed hypochondrium pain, obstruction of qi in the chest shouting pain, injury from falling down, traumatism and bleeding.Dalbergia wood volatile oil and aqua aromatica thereof have anti thrombotic action, and yellow wingceltis have faint anticoagulation, significantly can increase coronary flow, reducing heart rate, and slight increase heartbeat amplitude, does not cause cardiac arrhythmia.Dalbergia wood ethanol extract has anticonvulsion, analgesic activity.Experiment shows that it injects the blood high viscosity syndrome formed syndrome of blood stasis animal capable to high molecular dextran makes WBV show and reduces, especially with WBV effect under reducing high shear rate be, also plasma viscosity can be reduced, but to erythrocyte aggregation without significant impact, dalbergia wood reduces blood fat in addition, it reduces syndrome of blood stasis animal blood viscosity may be relevant with its effect for reducing fat, and the mechanism of its effect for reducing blood fat is then relevant with suppressing HMG CoA-reductase.

Lily: lily is except containing protein 21.29%, fat 12.43%, reduced sugar 11.47%, starch 1.61%, and calcium, phosphorus, iron, every hectogram is containing outside the nutrients such as 1.443 milligrams of Cobastabs, 21.2 milligrams of vitamin Cs, also containing some special nutritional labelings, as multiple alkaloids such as colchicins.These composition comprehensive functions, in human body, not only have the merit of good nutritious tonifying, but also to dry in autumn and multiple Seasonal diseases that is that cause has certain preventive and therapeutic effect.The traditional Chinese medical science is said fresh lily bulb has mental-tranquilization, the effect moistened the lung and relieve the cough, weakling is after being ill highly profitable.

The Radix Astragali: sweet, tepor; Return lung, spleen, liver, kidney channel.Essentials of Matea Medica: " Radix Astragali, raw with solid table, losslessly to send out, to have sweat to stop; Process with bowl spares, beneficial vigour, strong taste.Green blood, myogenic, apocenosis Neto, sore carbuncle panacea.Variola does not rise, and the deficiency of yang should it without hot person." " book on Chinese herbal medicine justice ": " temperature supports taste, and all middle gas is depressed for the Radix Astragali, soil in help, and spleen soil is weak, and the clear gas person of sinking is the most suitable.Its skin goes directly the skin table muscle of people, and solid protection defends sun, and enriching table point, is its speciality, so all diseases of exterior deficiency, and the most refreshing agent." function shows arrest sweating, inducing diuresis for removing edema admittedly, the apocenosis of holder sore, regulating fluid apssage.The Radix Astragali makes contractile ability strengthen, and can improve the blood circulation of whole body, can coronary artery dilator, Renal vascular and adder-wort peripheral vessel, make skin blood overactive circulation; The nonspecific immunity power of body can be improved, protect the liver and fall hypoglycemic effect, have inhibitory action to staphylococcus, blood dissolubility streptococcus, Diplococcus pneumopniae, shigella dysenteriae etc.The Radix Astragali can significantly affect SPL Information Conduction, realizes immunoregulation effect.Can be used for high blood pressure, ischemic heart disease, acute glomerulonephritis, gastric ulcer, psoriasis, diabetes, osteoporosis." Bencao Jingshu ": " the real table of function, has the evil person of table not use; Can help gas, gas reality person do not use; Can interiorly fill in, tonifying for the deficiency, chest diaphragm is gas-tight asks, stomach has stagnant person not use; Energy yang-tonifying, overabundance of YANG leading to deficiency of YIN person avoids it; Part of the body cavity above the diaphragm housing the heart and lungs heat is contained, and part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels cold of insufficiency type person avoids it; The many anger of patient, irritability discord person do not take; Variola blood system heat is notably forbidden.”

Adenophora tetraphylla: sweet, the micro-hardship of taste, cold nature, enters lung, stomach warp.Clearing heat and nourishing yin, moistens the lung and relieve the cough, the effect of nourishing the stomach to improve the production of body fluid, is mainly used in the lung-dryness syndrome due to yin deficiency, dry cough lacks phlegm, labor coughs phlegm blood, dry, the tracheitis of deficiency of stomach-Yin, mouthfeel pharynx, pertussis, cough with lung heat, the cards such as Huang is thick, the red few tongue of constipation, tongue of coughing up phlegm.The root of straight ladybell preserved material has obvious cardiotonic to Isolated Toad Heart, and the amplitude of the in vitro heart can be made to increase, and the ethanol extract of glehnia littoralis root can make the body temperature of normal rabbits slightly decline; Also cooling effect is had to causing the rabbit of heating because of antityphoid vaccine; And have analgesic activity (rabbit dental pulp electrostimulation).The root of straight ladybell water logging agent (1:2) has inhibitory action in various degree to pathogenic dermatophytes such as Austria big belly microspore Du tinea bacterium, ulotrichy microspore tinea bacterium in vitro.

Soil bone skin: nature and flavor are bitter, cold.1. " book on Chinese herbal medicine asks former ": " bitter sweet, flat." 2. " south of the Five Ridges gather medicinal herbs record ": " taste rock, cold in nature." 3. " Luchuan book on Chinese herbal medicine ": " is cool in nature, lightly seasoned." cure mainly heat-clearing, removing toxic substances, cool blood, pain relieving.Cure cold heating, cough, pharyngalgia, bleeding from five sense organs or subcutaneous tissue, dysentery characterized by blood in the stool, sore scabies, scrofula, treating swelling and pain by traumatic injury.1. " the sward property of medicine is standby to be wanted ": " heat that disappears poison, washes the rotten sore pain of Ci pin, with white lantern and Yan Suan Jiang pot beverage, i.e. alleviating pain and detumescence.Fall to beat and also use.The prosperous blood of red person, white person's sterilization." 2. " south of the Five Ridges gather medicinal herbs record ": " controls hernia, disappear fall beat red and swollen, scrofula core; Lump in abdomen, the heavily fortified point pressed pain, smash deposited it." 3. " Luchuan book on Chinese herbal medicine ": " cool serum liver, removing toxic substances of bringing down a fever.Control blood-head bleeding from five sense organs or subcutaneous tissue, pyreticosis dysentery characterized by blood in the stool." 4. Guangzhou army " conventional Chinese herbal medicine handbook ": " is clearing heat and detoxicating, cough-relieving analgesic therapy.Cure cold fever, pharyngalgia, cough, pulmonary tuberculosis; Stomachache, stomachache; Furunculosis furuncle."

Epipremnum pinnatunz: habitats distribution is in being born in thick forest.Distribution south China.Nature and flavor " thousand kinds, south China herbal medicine ": " light micro-puckery, flat." 1. function cures mainly " Wuzhou herbal medicine and the choosing of common disease frequently-occurring disease prescription ": " cool blood of clearing liver, subdhing swelling and detoxicating.Control red eye, swell pain, nosebleed epistaxis; Ulcer sore furuncle is controlled in external application, scrotal swelling, newborn sore." 2. " GUIHAIA register ": " root, rattan promoting blood circulation to remove blood stasis, clearing heat and promoting diuresis, swelling and pain relieving.Control to fall and beat, fracture, snakebite, carbuncle furuncle, pertussis, order pain, nosebleed epistaxis etc."

Semen Herpetospermi: nature and flavor are bitter; Cold in nature.Function cures mainly clearing liver cholagogic; Invigorating the spleen helps fortune.Main icteric catarrhal jaundice; Cholecystitis; Indigestion.

Phytolacca acinosa: nature and flavor are bitter, cold.1. " herbal classic ": " taste is pungent, flat." 2. " not Lu ": " acid, poisonous." 3. " detailed outline ": " is bitter, cold." return through entering spleen, urinary bladder channel." Thunder God concocts property of medicine solution ": " enter spleen, bladder, small intestine three warp." function cures mainly logical two just, water pouring, dissipating bind.Harness the river swollen, turgor, beriberi, larynx numbness, carbuncle swells, and dislikes sore.1. " herbal classic ": " main water swelling, hernia lump in the abdomen, numbness; Press except carbuncle swells." 2. " not Lu ": " treats perverse trend in the heart, oedema, impotence numbness, and the full flood of abdomen is straight, dredges the five internal organs, aproll gas." 3. " property of medicine opinion ": " can rush down ten kinds of edemas; Larynx numbness is obstructed, and thinly-sliced vinegar is endured, outer thin being recovered in the swollen place of larynx." 4. " Japan hanako materia medica ": " leads to intestine and small intestine, rushes down disease due to noxious agents produced by various parasites, induced abortion, and Xie pyogenic infections applies and dislikes sore." 5. " medical center bun is wanted ": " mill is coated with sore tinea, desinsection." 6. " Guizhou side's medicine among the people collection ": " subcutaneous ulcer of harnessing the Yellow River."

Radix Betae: nature and flavor are sweet is cool.1. " not Lu ": " sweetness and bitterness, Great Cold." 2. " Japan hanako materia medica ": " is cold, nontoxic." 3. " praise and help book on Chinese herbal medicine ": " is flat, micro-poison." 4. herbal for Relief of Famines: " taste is salty, and property is flat cold, micro-poison." return through 1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enters Yangming Channel." 2. " book on Chinese herbal medicine brief points ": " meridian of Foot-TAI YIN of starting with." function cures mainly clearing heat and detoxicating, and the row stasis of blood is stopped blooding.Controlling measles sends out unhappy thoroughly, hot malicious diarrhea, amenorrhoea stranguria with turbid discharge, and carbuncle is swollen traumatics fracture.1. " not Lu ": " row high fever when treating separates wind-heat poison." 2. Tang Materia Medica: " Xia Yue grinds with its dish and makes congee, antipyretic, stops pyrotoxic dysentery again.Smash deposited post-moxibustion sore, pain relieving." 3. supplement to the Herbal: " is smash strand juice and is taken it, main cold and hot dysentery.Hemostasia and promoting granulation again, people has and traumatics fracture, and applies it." 4. " Japan hanako materia medica ": " is processed and is made hot water drink, appetizing, logical heart diaphragm.Gas under " 5. " praise and help book on Chinese herbal medicine ": " bowl spares, reason temper, wind of decaptitating, sharp the five internal organs." 6. " occupying diet spectrum with breath ": " is relieved inflammation or internal heat and is dispeled the wind, and desinsection detoxifies, and wash dirt turbid, rare variola, is only with menstruation regulating, treating strangurialy controls dysentery, and children's married woman You Yi eats it." 7. " conventional glossary of Herbs and Drugs among the people ": " heat-clearing, promoting circulation of blood.Control anus to swell and ache." 8. " Traditional Chinese Medicine in Sichuan will ": " control measles from the beginning of, see a little thoroughly and color not red, and control women and stop the stasis of blood through closing, hemotoncus and anus swell and ache."

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 Chinese medicine additive

Paris polyphylla 4 weight portion, adder-wort 16 weight portion, field pennycress 18 weight portion, wolf's milk 22 weight portion, climbing groundsel 25 weight portion, moutan bark 23 weight portion, the radix paeoniae rubrathe 20 weight portion, fevervine 25 weight portion, the fruit of Rangoon creeper 26 weight portion, betel nut 19 weight portion, pumpkin seeds 20 weight portion, field thistle 18 weight portion, sophora flower 21 weight portion, cogongrass rhizome 18 weight portion, sheep hoof 15 weight portion, Japanses beauty-berry 17 weight portion, Artemisia anomala 18 weight portion, madder 24 weight portion, dalbergia wood 15 weight portion, lily 18 weight portion, the Radix Astragali 17 weight portion, adenophora tetraphylla 22 weight portion, soil bone skin 20 weight portion, Epipremnum pinnatunz 18 weight portion, Semen Herpetospermi 20 weight portion, Phytolacca acinosa 5 weight portion is with Radix Betae 6 weight portion.

Its preparation method comprises the following steps:

Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 3 times, mixture is the ethanol of 84%, be heated to boiling reflux 2 hours, filter, adopt percolation with the speed of 1ml per minute slowly diacolation, collect percolate, when being evaporated to 50 DEG C subsequently under vacuum 0.07Mpa, relative density is the lotion of 1.05, spraying dry, the EAT 150 DEG C of spray dryer, leaving air temp 85 DEG C, be ground into powder subsequently, make dried cream powder;

Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.1 times and 0.1 times in the dried cream powder obtained, makes particle, in 50 DEG C of dryings, obtains granule.

Embodiment 2 mixed feed

Corn 32 weight portion, wheat bran 24 weight portion, dregs of beans 6 weight portion, cotton dregs 4 weight portion, stone flour 0.3 weight portion, salt 0.3 weight portion, sunflower cake 3 weight portion, dusty yeast 1 weight portion, green hay 10 weight portion, calcium carbonate 0.2 weight portion, maize straw 25 weight portion, vinasse 1 weight portion, fish meal 2 weight portion, dried carrot 3 weight portion, oyster shell whiting 1 weight portion and Chinese medicine additive 7 weight portion.

Its preparation method comprises the following steps:

(1) pulverising step: take corn, wheat bran, dregs of beans, cotton dregs, sunflower cake, green hay, maize straw, vinasse, dried carrot and Chinese medicine additive by ratio of weight and the number of copies, drops into pulverizer and carries out Crushing of Ultrafine, crosses 3.5mm sieve and obtain fine powder after pulverizing;

(2) batching step: take stone flour, salt, dusty yeast, calcium carbonate, fish meal, oyster shell whiting and vitamine supplement according to ratio of weight and number, pulverizes with step (1) fine powder obtained and mixes, and drop into mixer, mix, incorporation time is 60s;

(3) granulation step: mixture is dropped into the water that granulator adds mixture quality 3 times amount, granulate, grain temperature is 75 DEG C, makes its gelatinization degree reach more than 94%.

(4) drying steps: the feed granules that step (3) obtains is carried out air-dry drying when temperature is 50 DEG C, obtains feed packing.

The toxicity test of Chinese medicine additive

1, trial drug: by Paris polyphylla 4g, adder-wort 16g, field pennycress 18g, wolf's milk 22g, climbing groundsel 25g, moutan bark 23g, radix paeoniae rubrathe 20g, fevervine 25g, fruit of Rangoon creeper 26g, betel nut 19g, pumpkin seeds 20g, field thistle 18g, sophora flower 21g, cogongrass rhizome 18g, sheep hoof 15g, Japanses beauty-berry 17g, Artemisia anomala 18g, madder 24g, dalbergia wood 15g, lily 18g, Radix Astragali 17g, adenophora tetraphylla 22g, native bone skin 20g, Epipremnum pinnatunz 18g, Semen Herpetospermi 20g, Phytolacca acinosa 5g with purple casserole is put in Radix Betae 6g mixing, add clear water, to clear water dipped medicinal material upper surface 4cm, soak 8 hours; Be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 50 minutes dosage to liquid be slowly 300ml, filters, obtain filtrate a, for subsequent use; The residue dregs of a decoction are added clear water again, to clear water dipped medicinal material upper surface 3cm, soaks 7 hours; Be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 35 minutes dosage to liquid be slowly 200ml, filters, obtain filtrate b, mixed by filtrate a and filtrate b.

2, test method: application NIH mouse 40, SPF level, male and female half and half, body weight 18 ~ 22g, trial drug is pressed 7.5 to mouse, 15.0, 30.0 and 45.0g crude drug/kg continuous use 16 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal after 4 weeks, result shows: this trial drug is to the hair of mouse, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, the indexs such as blood fat all have no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, Organs of Mice is all without obviously changing.Illustrate that Chinese medicine additive of the present invention is little to toxicity after mouse long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Contrast test

Purchase the sheep 5 batches cultivated without the Shandong Province of antibody 1 years old age, totally 800.Select 240 to test, be divided into 4 groups at random, often organize 60, be i.e. mixed feed group, western medicine group, infection control group and blank group.

Intoxicating material: Type B Nuo Weishi clostridium.

Trial drug: embodiment 2 mixed feed and conventional feed, and Western medicine anti-Nuo Weishi clostridium serum (every milliliter containing 7500IU) treatment.

Process: blank group does not infect Type B Nuo Weishi clostridium, all the other respectively organize sheep all through infecting the process of Type B Nuo Weishi clostridium.

Treatment: mixed feed group is normally fed with embodiment 2 mixed feed after infection Type B Nuo Weishi clostridium, is used in conjunction 3d.

Western medicine group is with anti-Nuo Weishi clostridium serum (every milliliter containing 7500IU) injection for curing after infection Type B Nuo Weishi clostridium, and conventional feed of normally feeding, is used in conjunction 3 d.

Blank group need not any drug therapy, conventional feed of feeding.

Infecting control group need not any drug therapy, conventional feed of feeding.

Result of the test

After Type B Nuo Weishi clostridium, morbidity sheep occurs that symptom is as follows: ill domestic animal falls group, does not eat, expiratory dyspnea, and body temperature about 41.5 DEG C is prostrate in lethargic sleep, and maintenance has no painfully to die suddenly in this state.Dissect disease sheep corpse, venae subcutaneae is significantly congested, and its skin is furvous outward appearance.Subcutaneous tissue of chest's oedema.Serous cavity has liquid to ooze out, and is exposed to air and is easy to solidify, and liquid is often in yellow, but peritoneal fluid slightly color.Often hemorrhage under endocardium of left ventricle.Abomasum pyloric part and little enteremia and hemorrhage.The congested swelling of liver, can see from surface or touch one to multiple coagulation necrosis stove, the distinct of necrosis region, lark, not full circle shape, around the cherry hyperemia band of Chang Weiyi around, necrosis region diameter can reach 2 ~ 3cm, and tangent plane becomes semicircle.Namely sheep black disease is judged as.

Record the survival rate after metainfective morbidity number and treatment and the death rate.See table 1

As can be seen from Table 1, after Type B Nuo Weishi clostridium, all there is incidence in various degree in mixed feed group, western medicine group and infection control group.Through treatment, the treatment survival rate of mixed feed group is all higher than western medicine group, more higher than infection control group.Therefore, can learn, mixed feed of the present invention, while feeding, treat sheep black disease, effective, determined curative effect.

Model case: Linyi sheep raiser, cultivation has 600 sheep, occurs sheep black disease epidemic situation, dead 50, symptom: ill domestic animal falls group, does not eat, expiratory dyspnea, body temperature about 41.5 DEG C, prostrate in lethargic sleep, and maintenance has no painfully to die suddenly in this state.Dissect disease sheep corpse, venae subcutaneae is significantly congested, and its skin is furvous outward appearance.Subcutaneous tissue of chest's oedema.Serous cavity has liquid to ooze out, and is exposed to air and is easy to solidify, and liquid is often in yellow, but peritoneal fluid slightly color.Often hemorrhage under endocardium of left ventricle.Abomasum pyloric part and little enteremia and hemorrhage.The congested swelling of liver, can see from surface or touch one to multiple coagulation necrosis stove, the distinct of necrosis region, lark, not full circle shape, around the cherry hyperemia band of Chang Weiyi around, necrosis region diameter can reach 2 ~ 3cm, and tangent plane becomes semicircle, is namely judged as sheep black disease.Select 300 sick sheep, adopt the mixed feed of embodiments of the invention 2 normally to feed, treat 3, cure 297 sheep, dead 3, survival rate 99%.

The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (9)

1. a sheep mixed feed, it is characterized in that, described mixed feed comprises following raw material: corn, wheat bran, dregs of beans, cotton dregs, stone flour, salt, sunflower cake, dusty yeast, green hay, calcium carbonate, maize straw, vinasse, fish meal, dried carrot, oyster shell whiting and vitamine supplement.

2. sheep mixed feed according to claim 1, it is characterized in that, in described feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 20-28 weight portion, dregs of beans 6-8 weight portion, cotton dregs 3-6 weight portion, stone flour 0.1-0.6 weight portion, salt 0.2-0.8 weight portion, sunflower cake 2-4 weight portion, dusty yeast 1-2 weight portion, green hay 10-15 weight portion, calcium carbonate 0.2-0.4 weight portion, maize straw 25-30 weight portion, vinasse 1-2 weight portion, fish meal 2-3 weight portion, dried carrot 3-6 weight portion, oyster shell whiting 1-2 weight portion and vitamine supplement 0.001-0.002 weight portion.

3. sheep mixed feed according to claim 1 and 2, it is characterized in that, described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn 30-40 weight portion, wheat bran 20-28 weight portion, dregs of beans 6-8 weight portion, cotton dregs 3-6 weight portion, stone flour 0.1-0.6 weight portion, salt 0.2-0.8 weight portion, sunflower cake 2-4 weight portion, dusty yeast 1-2 weight portion, green hay 10-15 weight portion, calcium carbonate 0.2-0.4 weight portion, maize straw 25-30 weight portion, vinasse 1-2 weight portion, fish meal 2-3 weight portion, dried carrot 3-6 weight portion, oyster shell whiting 1-2 weight portion, vitamine supplement 0.001-0.002 weight portion and Chinese medicine additive 6-8 weight portion.

4. the sheep mixed feed according to any one of claim 1-3, it is characterized in that, in described feed, the parts by weight of each raw material are: corn 32 weight portion, wheat bran 24 weight portion, dregs of beans 6 weight portion, cotton dregs 4 weight portion, stone flour 0.3 weight portion, salt 0.3 weight portion, sunflower cake 3 weight portion, dusty yeast 1 weight portion, green hay 10 weight portion, calcium carbonate 0.2 weight portion, maize straw 25 weight portion, vinasse 1 weight portion, fish meal 2 weight portion, dried carrot 3 weight portion, oyster shell whiting 1 weight portion, vitamine supplement 0.001 weight portion and Chinese medicine additive 7 weight portion.

5. the sheep mixed feed according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: Paris polyphylla, adder-wort, field pennycress, wolf's milk, climbing groundsel, moutan bark, the radix paeoniae rubrathe, fevervine, the fruit of Rangoon creeper, betel nut, pumpkin seeds, field thistle, sophora flower, cogongrass rhizome, sheep hoof, Japanses beauty-berry, Artemisia anomala, madder, dalbergia wood, lily, the Radix Astragali, adenophora tetraphylla, Tu Gupi, Epipremnum pinnatunz, Semen Herpetospermi, Phytolacca acinosa and Radix Betae.

6. the sheep mixed feed according to any one of claim 1-5, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Paris polyphylla 4-6 weight portion, adder-wort 10-20 weight portion, field pennycress 10-18 weight portion, wolf's milk 12-22 weight portion, climbing groundsel 15-25 weight portion, moutan bark 10-23 weight portion, radix paeoniae rubrathe 10-20 weight portion, fevervine 12-25 weight portion, fruit of Rangoon creeper 13-36 weight portion, betel nut 12-29 weight portion, pumpkin seeds 14-30 weight portion, field thistle 15-28 weight portion, sophora flower 15-31 weight portion, cogongrass rhizome 10-24 weight portion, sheep hoof 10-20 weight portion, Japanses beauty-berry 12-27 weight portion, Artemisia anomala 10-20 weight portion, madder 12-24 weight portion, dalbergia wood 10-15 weight portion, lily 15-28 weight portion, Radix Astragali 10-24 weight portion, adenophora tetraphylla 12-24 weight portion, soil bone skin 10-20 weight portion, Epipremnum pinnatunz 10-18 weight portion, Semen Herpetospermi 12-20 weight portion, Phytolacca acinosa 4-7 weight portion is with Radix Betae 4-6 weight portion.

7. the sheep mixed feed according to any one of claim 1-6, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Paris polyphylla 4 weight portion, adder-wort 16 weight portion, field pennycress 18 weight portion, wolf's milk 22 weight portion, climbing groundsel 25 weight portion, moutan bark 23 weight portion, the radix paeoniae rubrathe 20 weight portion, fevervine 25 weight portion, the fruit of Rangoon creeper 26 weight portion, betel nut 19 weight portion, pumpkin seeds 20 weight portion, field thistle 18 weight portion, sophora flower 21 weight portion, cogongrass rhizome 18 weight portion, sheep hoof 15 weight portion, Japanses beauty-berry 17 weight portion, Artemisia anomala 18 weight portion, madder 24 weight portion, dalbergia wood 15 weight portion, lily 18 weight portion, the Radix Astragali 17 weight portion, adenophora tetraphylla 22 weight portion, soil bone skin 20 weight portion, Epipremnum pinnatunz 18 weight portion, Semen Herpetospermi 20 weight portion, Phytolacca acinosa 5 weight portion is with Radix Betae 6 weight portion.

8. the sheep mixed feed according to any one of claim 1-7, is characterized in that, the preparation method of described Chinese medicine additive comprises the following steps:

Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 3 ~ 5 times, mixture is the ethanol of 84% ~ 95%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.07 ~ 0.09Mpa, relative density is the lotion of 1.05 ~ 1.10, spraying dry, the EAT 150 ~ 165 DEG C of spray dryer, leaving air temp 70 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;

Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.1 ~ 0.3 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes particle, in 45 ~ 50 DEG C of dryings, obtains granule.

9. the preparation method of the sheep mixed feed according to any one of claim 1-8, is characterized in that, described preparation method comprises the following steps:

(1) pulverising step: take corn, wheat bran, dregs of beans, cotton dregs, sunflower cake, green hay, maize straw, vinasse, dried carrot and Chinese medicine additive by ratio of weight and the number of copies, drops into pulverizer and carries out Crushing of Ultrafine, crosses 3.5mm sieve and obtain fine powder after pulverizing;

(2) batching step: take stone flour, salt, dusty yeast, calcium carbonate, fish meal, oyster shell whiting and vitamine supplement according to ratio of weight and number, pulverizes with step (1) fine powder obtained and mixes, and drop into mixer, mix, incorporation time is 50-60s;

(3) granulation step: mixture is dropped into the water that granulator adds mixture quality 2-3 times amount, granulate, grain temperature is 70-85 DEG C, makes its gelatinization degree reach more than 94%;

(4) drying steps: the feed granules that step (3) obtains is carried out air-dry drying when temperature is 50 DEG C-60 DEG C, obtains feed packing.