CN103860627A - Pithecellobium clypearia antibiosis veterinary drug - Google Patents
Pithecellobium clypearia antibiosis veterinary drug Download PDFInfo
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- CN103860627A CN103860627A CN201210524344.3A CN201210524344A CN103860627A CN 103860627 A CN103860627 A CN 103860627A CN 201210524344 A CN201210524344 A CN 201210524344A CN 103860627 A CN103860627 A CN 103860627A
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- pithecellobium clypearia
- antibiosis
- ramulus
- veterinary drug
- pithecellobii lucidi
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Abstract
The invention provides a pithecellobium clypearia antibiosis veterinary drug, which is used for preventing and controlling bacterial diseases such as livestock upper respiratory infection, acute gastrointestinal tract disease and the like. The pithecellobium clypearia antibiosis veterinary drug is composed of pithecellobium clypearia and dandelion according to weight ratio of 10-30: 15-45. The pithecellobium clypearia antibiosis veterinary drug is selected from pithecellobium clypearia and dandelion in south lands, and is prepared by combining a traditional production technology and a modern preparation production technology, has the advantages of less amount, clear curative effect, no medicament residue, little toxic and side effect, difficult drug resistance generation and no environmental pollution, and is very suitable for modern breeding industry.
Description
Technical field
The invention belongs to veterinary drug technical field, specially refer to a kind of fowl poultry upper respiratory tract infection Antibacterial medicines as loose in the Ramulus Et Folium Pithecellobii Lucidi of the bacterial diseasees such as laryngotracheitis, bronchitis, pharyngolaryngitis, pneumonia and cough due to lung-heat, acute enteritis and dysentery that can be used for preventing and treating.
Background technology
At present, along with aquaculture scale constantly expands, intensive degree improves constantly, that fowl diseases shows is multiple, take place frequently and complicated feature, to the more difficult of preventing and treating of livestock and poultry, respiratory tract disease and intestinal tract disease are the high morbidities of poultry first, and its sickness rate is more than 70%, cause huge economic loss to aquaculture, have a strong impact on culture benefit.Simultaneously, due to people's a large amount of drug resistance generation and pollutions to environment that use chemical medicine and antibiotic to cause in livestock and poultry disease control and prevention, people's food safety in the drug residue serious threat of livestock product, and these problems all affect health and the sustainable development of industry.
Summary of the invention
The object of the invention is to propose the loose Antibacterial medicines of a kind of Ramulus Et Folium Pithecellobii Lucidi, for bacterial diseasees such as control fowl poultry upper respiratory tract infection, acute gastroenteropathys.
The loose Antibacterial medicines of Ramulus Et Folium Pithecellobii Lucidi of the present invention is made up of according to the weight ratio of 10～30:15～45 Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci.
Further; it is that the ultra micro powder of 3-5 μ m mixes that the loose Antibacterial medicines of above-mentioned Ramulus Et Folium Pithecellobii Lucidi grinds into fineness of the particles by Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci; Chinese crude drug effective ingredient after cell wall breaking discharges completely; be conducive to poultry body to the absorbing of medicine, its therapeutic effect has qualitative leap.
Ramulus Et Folium Pithecellobii Lucidi (Folium Archidendri) is the Ramulus Et Folium Pithecellobii Lucidi platymiscium of pulse family Mimosoideae, have another name called land three money, flood dragon wood, chicken three-tree, enclose birth tree, hair washing wood, the south China, the southwest that are mainly distributed in China, its leaf, fruit, seed all can be used as medicine.Pharmaceutical research shows, Ramulus Et Folium Pithecellobii Lucidi has the multiple pharmacological effect such as antiinflammatory, analgesia, antibacterial, antitoxin.The effective ingredient that Ramulus Et Folium Pithecellobii Lucidi extracorporeal antivirus effect works is flavone and Flavane compound, and its In Vitro Anti respiratory syncytial virus (RSV) activity is even better than positive control drug ribavirin; Main effective ingredient gallic acid can significantly suppress the T lymphopoiesis of ConA induction; Ramulus Et Folium Pithecellobii Lucidi water extract or alcohol extract infected by influenza first 3 types, Parainfluenza type 1 virus (HVJ), respiratory syncytial virus (RSV), herpes simplex virus type 1 and 2 type (HSV-1, HSV-2), enterovirus Cox B3, rhinovirus (RV), mumps virus all have inhibitory action, and have very strong antioxidant activity.
According to theory of Chinese medical science, Chinese herbal medicine Ramulus Et Folium Pithecellobii Lucidi mildly bitter flavor, puckery, cold nature; Return lung, stomach, large intestine channel (also having the document book that is attributed to spleen, stomach, Liver Channel); Having the effects such as heat-clearing and toxic substances removing, removing heat from blood detumescence, antidiarrheal, is the conventional Chinese herbal medicine in In Guangdong Province, the treatment that is used for the diseases such as laryngopharynx swelling and pain, gastroenteritis, burn, scald, carbuncle sore furuncle and phyma among the people.
Herba Taraxaci has another name called Hemerocallis citrina Baroni Seedling, Po Poding, Herba crotalariae albidae etc., is feverfew Herba Taraxaci whole herb with root, is born in hillside, Tian Bian, roadside, river shoal and wilderness more, and all there is wild distribution all parts of the country.Modern pharmacological research discovery, Herba Taraxaci has stronger bactericidal action to Staphylococcus aureus Resistant strain, Hemolytic streptococcus, and Diplococcus pneumoniae, meningococcus, various bacillus and micrococcus catarrhalis are all had to certain bactericidal action.In addition, Herba Taraxaci also has anti-gastric-ulcer, function of gallbladder promoting, the effect such as protects the liver.
By flavour of a drug composition of the present invention and usage ratio, make pulvis, raise upper respiratory tract infection as diseases such as laryngotracheitis, bronchitis, pharyngolaryngitis, pneumonia and cough due to lung-heat, acute enteritis and dysentery for prevention and treatment fowl clinically, can obtain good prevention effect.
The loose Antibacterial medicines of Ramulus Et Folium Pithecellobii Lucidi of the present invention is selected from southern characteristic real estate Chinese herbal medicine Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci, make in conjunction with modern preparation production technology with traditional processing technology, there is consumption few, curative effect is clear and definite, drug residue free, toxic and side effects is little, is not easy to produce drug resistance, to features such as environmental health can not pollute, be very suitable for modern farming.
Detailed description of the invention
Below by the description to embodiment, the specific embodiment of the present invention is described in further detail as effect and the operation principle etc. of the mutual alignment between the shape of related each member, structure, each several part and annexation, each several part.
Embodiment 1:
It is that the ultra micro powder of 3-5 μ m mixes that the loose Antibacterial medicines of the Ramulus Et Folium Pithecellobii Lucidi of the present embodiment grinds into fineness of the particles by Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci according to the weight ratio of 10:45.
Following table is to measure the test result of this prescription drug inhibition zone of encountered pathogenic microorganism on veterinary clinic with paper disk method:
| Test organisms | Antibacterial circle diameter mm | Sensitivity |
| Fowl Mycoplasma (MGS6 strain) | 18.90±0.51 | Extremely sensitive |
| Staphylococcus aureus | 18.25±0.48 | Extremely sensitive |
| Escherichia coli (O78 serotype) | 17.60±0.55 | Extremely sensitive |
| Pasteurellosis bacillus | 18.53±0.70 | Extremely sensitive |
| Salmonella | 19.12±0.64 | Extremely sensitive |
Note: antibacterial circle diameter is greater than 20mm and is judged to extremely sensitivity, is extremely sensitive between 20～14.5mm, is middle sensitivity between 14.5～10mm, and being less than 10.5mm is low sensitivity.
Above-mentioned test shows, this product has good inhibitory action to pathogenic microorganism common on veterinary clinic.
Embodiment 2:
It is that the ultra micro powder of 3-5 μ m mixes that the loose Antibacterial medicines of the Ramulus Et Folium Pithecellobii Lucidi of the present embodiment grinds into fineness of the particles by Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci according to the weight ratio of 30:45.
Escherichia coli, Salmonella mixed infection are suffered from by certain plant sick chicken to making a definite diagnosis adopts the loose Antibacterial medicines of Ramulus Et Folium Pithecellobii Lucidi to feed in 2% ratio mixed feeding, and the ampicillin of same ratio for contrast groups, is used in conjunction 4 days, and result is as shown in the table:
Above-mentioned test shows, than ampicillin, this product to suffer from the sick chicken of escherichia coli, Salmonella mixed infection have respond well to treatment fast, the feature that effective percentage is high.
Embodiment 3:
It is that the ultra micro powder of 3-5 μ m mixes that the loose Antibacterial medicines of the Ramulus Et Folium Pithecellobii Lucidi of the present embodiment grinds into fineness of the particles by Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci according to the weight ratio of 30:15.
Certain plant suffers from pasteurellosis bacillus chicken and mines massively and feed in 2% ratio mixed feeding with the loose Antibacterial medicines of Ramulus Et Folium Pithecellobii Lucidi making a definite diagnosis, and contrast groups 0.1% Embazin, is used in conjunction 4 days, and result is as shown in the table:
Above-mentioned test shows, than Embazin, this product to suffer from pasteurellosis bacillus chicken group have respond well to treatment fast, the feature that effective percentage is high.
Claims (2)
1. the loose Antibacterial medicines of Ramulus Et Folium Pithecellobii Lucidi, is characterized in that being made up of according to the weight ratio of 10～30:15～45 Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci.
2. the loose Antibacterial medicines of Ramulus Et Folium Pithecellobii Lucidi according to claim 1, is characterized in that grinding into fineness of the particles by Ramulus Et Folium Pithecellobii Lucidi, Herba Taraxaci is that the ultra micro powder of 3-5 μ m mixes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210524344.3A CN103860627A (en) | 2012-12-10 | 2012-12-10 | Pithecellobium clypearia antibiosis veterinary drug |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210524344.3A CN103860627A (en) | 2012-12-10 | 2012-12-10 | Pithecellobium clypearia antibiosis veterinary drug |
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| CN103860627A true CN103860627A (en) | 2014-06-18 |
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| CN201210524344.3A Pending CN103860627A (en) | 2012-12-10 | 2012-12-10 | Pithecellobium clypearia antibiosis veterinary drug |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107812033A (en) * | 2017-12-07 | 2018-03-20 | 成都乾坤动物药业股份有限公司 | A kind of Chewable Tablets of Chinese traditional medicine for treating pet disease of digestive tract and its production and use |
| CN108379467A (en) * | 2018-05-02 | 2018-08-10 | 安徽安丰堂动物药业有限公司 | A kind of herbal medicine of prevention poultry infection of the upper respiratory tract tranquilizing and allaying excitement |
| EP3456335A4 (en) * | 2016-05-10 | 2019-05-08 | Sun Yat-Sen University | Pithecellobium clypearia benth, extract and application for preparing anti-microbial agent |
| CN113397041A (en) * | 2021-06-28 | 2021-09-17 | 广东温氏大华农生物科技有限公司 | Application of flood dragon wood in livestock breeding |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032547A (en) * | 2006-03-07 | 2007-09-12 | 广东奇方药业有限公司 | Anti-inflammatory and antivirotic medicine composition |
-
2012
- 2012-12-10 CN CN201210524344.3A patent/CN103860627A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032547A (en) * | 2006-03-07 | 2007-09-12 | 广东奇方药业有限公司 | Anti-inflammatory and antivirotic medicine composition |
Non-Patent Citations (2)
| Title |
|---|
| 张中贤等: "猴耳环水提取物抗流感病毒的实验研究", 《中国热带医学》 * |
| 李药兰等: "猴耳环抗病毒有效成分研究", 《中国中药杂志》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3456335A4 (en) * | 2016-05-10 | 2019-05-08 | Sun Yat-Sen University | Pithecellobium clypearia benth, extract and application for preparing anti-microbial agent |
| US11491198B2 (en) | 2016-05-10 | 2022-11-08 | Sun Yat-Sen University | Method of chinese herbal medicine extract used for treating multiple diseases caused by drug resistant bacteria infection |
| CN107812033A (en) * | 2017-12-07 | 2018-03-20 | 成都乾坤动物药业股份有限公司 | A kind of Chewable Tablets of Chinese traditional medicine for treating pet disease of digestive tract and its production and use |
| CN108379467A (en) * | 2018-05-02 | 2018-08-10 | 安徽安丰堂动物药业有限公司 | A kind of herbal medicine of prevention poultry infection of the upper respiratory tract tranquilizing and allaying excitement |
| CN113397041A (en) * | 2021-06-28 | 2021-09-17 | 广东温氏大华农生物科技有限公司 | Application of flood dragon wood in livestock breeding |
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Application publication date: 20140618 |