CN102894200A - Foodstuff additive used for enhancing sheep antibiosis and anti-virus, and preparation method thereof - Google Patents
Foodstuff additive used for enhancing sheep antibiosis and anti-virus, and preparation method thereof Download PDFInfo
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- CN102894200A CN102894200A CN2011102156307A CN201110215630A CN102894200A CN 102894200 A CN102894200 A CN 102894200A CN 2011102156307 A CN2011102156307 A CN 2011102156307A CN 201110215630 A CN201110215630 A CN 201110215630A CN 102894200 A CN102894200 A CN 102894200A
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Abstract
The invention relates to a foodstuff additive used for enhancing sheep antibiosis and anti-virus, and a preparation method thereof. The traditional Chinese medicine preparation is manufactured by the following raw materials of, by weight, 8-10 parts of cabline patchouli, 8-10 parts of herba elsholtziae, 8-10 parts of radix scutellariae, 2-10 parts of honeysuckle stem, 2-10 parts of dandelion, 2-10 parts of fructus forsythiae, 2-8 parts of astragalus mongholicus, 5-10 parts of rhizoma atractylodis macrocephalae, 2-8 parts of dried tangerine or orange peel, 0.1-3 parts of flos caryophylli, 1-5 parts of fennel and 5-8 parts of radix glycyrrhizae.
Description
The present invention relates to a kind of for strengthening the antiviral foodstuff additive of goat-anti bacterium and preparation method.Belong to medical technical field.
Background technology:
The our times various countries are that animal food has outstanding importance in food security for food security growing interest, excellent its.In the sheep raising industry, what the raiser was afraid of most is exactly that sheep is sick, tends at medium-term and long-term some antibiotic that add of feed as prophylactic.Will cause like this bacterial virus to develop immunity to drugs, the body immune system of sheep sustains damage, the dead group of group namely can occur hinders, suffers heavy losses, especially large-scale centralized formula sheep raising factory, morbidity quantity is increased sharply rapidly young sheep diarrhea, middle llama, influenza pestilence if propagate and morbidity is exceedingly fast, popularly very extensively, very harmful prevents improperly, cause serious economic loss, add that present domestic recessive sheep pest are quite serious then can for the sheep raising family.This is sick anti-to overweight and controls very mainly, and above-mentioned sheep disease poultry feeders often will be injected antiviral vaccine to sheep, but this can only play certain prevention effect, infects but group's sheep disease poison occurs, and it is still helpless.In therapeutic process; the animal doctor can give sheep intramuscular injection and more oral antiviral chemicalses usually; such as the Amoxicillin, sulfamido, kanamycins; amikacin; Ciprofloxacin, amantadines etc. are though these medicines have certain curative effect; but it all has very large toxic and side effect, and can cause the damage of sheep vivo immuning system.Hypoimmunity, drug accumulation.Cause mutton that a large amount of antibiotic residues are arranged.Quality descends, and this causes very big hidden danger and threat can for undoubtedly human body health.The expert of the World Health Organization points out: livestock is used antibiotic in a large number, can pass to the mankind by food, and therefore its result, appeals antibiotic is used in the livestock restriction so that human some diseases is difficult to cure.Report for work according to relevant, European Union member countries forbid adding all antibiotic with the legislation form in animal feed, source for open feed addictive, overcome above-mentioned shortcoming, and Chinese herbal medicine is just with the mode of action of its uniqueness, good result, noresidue are without the resistance to the action of a drug and pollution-free and be subject to the favor of vast Scientific Research Workers.China is vast in territory, and Chinese herbal medicine resource is very abundant, aspect the development Chinese herbal feed additive advantageous advantage is being arranged.Our institute of Traditional Chinese Medicine and materia medica utilization put into practice for many years clinical experience accumulation, draw the elite of secret prescription handed down in the family from generation to generation in conjunction with the analysis of modern high technology pharmacology pathology, take the property of medicine of natural Chinese medicinal herb (yin, yang, cold, cool, temperature, heat), flavour of a drug---the traditional theory that concerns between (hot, sour, sweet, salty) and thing is as basic.Take modernized animal nutrition and disease prevention and cure theory as guidance, mix together at all times, fine screen is carefully selected, eliminate the false and retain the true, and by a large amount of clinical testings, sum up to conclude natural medicinal plant preparation of the present invention, be used for overcoming the defective of antibiotic residue problem, and provide a kind of immunity of organisms that can strengthen sheep, anti diar rhea, antiviral, improve the meat taste and improve meat nutrition.Imperative in the hope of producing " nonreactive meat ".
Summary of the invention:
The object of the present invention is to provide a kind of pure natural Chinese herbal and crude drugs preparations that utilizes, can not only suffer from diarrhoea to goat-anti, resisiting influenza virus, and can growth promotion, improve that to improve meat bright fragrant delicious.Another problem that need to solve of the present invention provides the preparation method of this Chinese medicine preparation.
For achieving the above object, the technical solution used in the present invention is: 1, be used for strengthening the antiviral foodstuff additive of goat-anti bacterium, it is characterized in that it is to be made by the raw material of following weight proportioning:
Be used for strengthening the antiviral foodstuff additive of goat-anti bacterium, it is characterized in that: the weight ratio of described each raw material is:
The preparation method who is used for the antiviral foodstuff additive of enhancing goat-anti bacterium is characterized in that it is undertaken by following operation:
A, batching: take by weighing the raw material Chinese herbal medicine by consumption;
B, screening: the impurity of removing the raw material Chinese herbal medicine;
C, drying and crushing: each raw material drying is ground into fine powder (No. six sieve) and mixes, the pulvis finished product.
D, packing is up to the standards.
A, batching: take by weighing Chinese herbal medicine by the said ratio consumption;
B, screening: the impurity of removing the raw material medium-height grass;
C, drying and crushing: the Chinese medicine that is up to the standards is taken by weighing and is ground into fine powder, mixes by the double accurate measurement of prescription requirement, powder;
D, compressing grains: the starch and the water-soluble solution that add 2-3 part mix, and are pressed into particle;
Require to carry out weight packaging according to dosage after e, the passed examination.
Technological process: detect → get the raw materials ready → quantitatively → sieve → mix → component → packing
Also available pulverizing mill is smashed to 3 micron granularities mixing the Chinese medicine meal, adds water.Then the High Rotation Speed seperator obtains liquid, through concentrated, gets concentrated medicament again, is convenient to transportation.Diluting this liquid during use gets final product.
The present invention is based on traditional Chinese medicine and pharmacy for the understanding of disease pathogenesis and the principle for the treatment of, through Long-term clinical and to exploration and the research of Chinese medicine, and according to the physiological and pathological feature of sheep, rationally determine, behind reason, method, side, the medicine, one group of medicament that is comprised of natural Chinese medicinal herb is fed mutton sheep as feed addictive.To anti diar rhea, anti influenza, anti-sheep pest, enhancing immunity growth promotion, improve the meat taste and all can play good effect.Elite composition contained in the pure natural Chinese herbal medicine can play the aromatization temperature to mutton sheep, invigorating the spleen and in, clearing away heat to stop diarrhea, anti-inflammation, the fragrant tender effect of meat flavour.All natural Chinese medicinal herb of the present invention are conventional medicine, aboundresources, cheap, with its as sheep feed additive long-term or short-term take, the use of substitute antibiotics does not namely produce any toxic side effects, and can obviously prevent and treat again each age group and easily send out disease.Improve production performance, improve the meat taste.Obtain higher economic benefit with lower input, and antibiotic residue provides effective approach in the mutton in order to reduce.Composition principle is as follows: in the prescription: Pogostemon cablin, elscholtiza, the root of large-flowered skullcap, for monarch drug in a prescription, Pogostemon cablin be labiate.Its hot slightly warm in nature of distinguishing the flavor of is nontoxic, returns taste lung three warps.Have: aromatization temperature and middle preventing or arresting vomiting, the loose table heresy of a surname, the effect of promoting qi circulation, resolving food retention.Modern medicine study proves, contains volatile oil 0.28% in the Pogostemon cablin, and contains anethole, citrene, B-elemene, cloves alkene, a-ylangene, B-farnesene, calamus alkene etc.Flavone compound: robinin, lime tree element, linarin, ageratum glucoside, Daucosterol etc.
Antibacterial action: China book on Chinese herbal medicine record test tube experiment ageratum has inhibitory action to multiple pathogenic funguses such as Trichophyton schoenleinis.The in vitro test Pogostone has obvious inhibitory action to Candida albicans, Cryptococcus neoformans, rhizopus niger etc.Staphylococcus aureus, α-hemolytic streptococcus etc. also there is certain inhibitory action.Elscholtiza is labiate, and flavor is hot, slightly warm in nature, has and middle dampness elimination, line water detumescence, inducing sweat and dispelling exogenous evils function.Cure mainly: catch cold, internal injury vomits and diarrhoea in wet, vomiting and diarrhoea, difficult urination, oedema, main abdominal pain due to acute vomiting and diarrhea.
" China's book on Chinese herbal medicine " record: chemical analysis: the elscholtiza herb contains volatile oil 0.10%.Include carvacrol 71.64%, Thymol 9.82 and P-cymene 10.10%, elsholtziakesone are accounted for volatile oil 85%, other contains acetophenone, B-sitosterol, glycoside.D-galactopyranose glucoside etc.Pharmacological action has, immunity, anti-inflammation are eased pain, strengthened to bright heat.Herba Moslae volatile oil has stronger broad-spectrum antibacterial action.Antibacterial action intensity to golden Portugal bacterium, micrococcus catarrhalis and bacterium flexneri is higher than iodine liquid, in addition, volatile oil all has remarkable antibacterial action to Escherichia coli, beta streptococcus, typhoid bacillus, shigella dysenteriae, corynebacterium diphtheriae, pneumobacillus, proteus, bacillus anthracis, edge purulence bacillus and meningococcus etc.Influenza A virus and orphan virus there is remarkable inhibitory action." book on Chinese herbal medicine is looked for the truth " " smell perfume (or spice) alters, like attribute temperature, be not heavy trembling with fear.”
The root of large-flowered skullcap is labiate, and bitter is cold in nature, return lung, courage, spleen, large intestine, small intestinl channel, has: heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive function.Root of large-flowered skullcap chemical composition contains: root contains flavone compound, baicalein, baicalin, oroxylin, methoxyl group flavanones, rhamanopyranosyl, asafoetide acyl group, glycoside, Arabic glucoside, goes Chinese first baicalein etc. that staphylococcus, hemolytic streptococcus, corynebacterium diphtheriae, typhoid bacillus and comma bacillus are had stronger bacteriostasis, and streptococcus pneumonia, shigella dysenteriae, Escherichia coli, paratyphosum Bacterium, proteus and edge purulence bacillus are also had bacteriostasis.To will congratulate, this is close, Fu Shi and bacterium sonnei all have and suppress or killing action.Select its above-mentioned three flavors to do altogether monarch drug in a prescription, mutually take together.To young sheep diarrhea, in, llama respiratory tract infection, influenza, all can play preventive and therapeutic effect without Ming Gaore etc.
In the prescription: caulis lonicerae, dandelion, the capsule of weeping forsythia, be ministerial drug, wherein caulis lonicerae is the caprifoliaceae plant cauline leaf, its flavor is sweet, cold nature, have clearing heat and detoxicating, dispelling wind vein relaxing function, cure mainly the warm disease heating, the diseases such as toxic-heat and blood stasis, modern medicine study proves, bear and contain chlorogenic acid in the rattan, the two galactosides of isochlorogenic acid compounds and cyanidenon 7-0, honeysuckle element-6 sandlwood glycosides, sitosterol, glucose and various trace elements, but its pharmacological action resisting pathogenic microbes is to Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, white is read coccus, ox type Brucella has inhibitory action.Record in " book on Chinese herbal medicine is looked for the truth ", dandelion is the whole herb with root of feverfew, its bitter is cold in nature, have clearing heat and detoxicating, dispersing swelling and dissipating binds, the inducing diuresis for treating strangurtia function cures mainly all and treats sores pain ulcers, the malicious all cards of red and swollen heat.The capsule of weeping forsythia is Oleaceae plants.The bitter cold nature, return lung heart small intestinl channel, have clearing heat and detoxicating, dispersing swelling and dissipating binds.Cure mainly anemopyretic cold, warm disease, pain subcutaneous ulcer pyogenic infections.Chemical analysis contains: phillygenin, dextrorotation pine ester phenol flavone compound, rutin, capsule of weeping forsythia fat glucoside, hexamethylene alcohol ketone, triterpenes contains thing etc.Its pharmacology has anti-microbial effect.To staphylococcus aureus, hemolytic streptococcus, micrococcus catarrhalis, Pseudomonas aeruginosa, headgrit bacillus, bacillus anthracis, corynebacterium diphtheriae etc. have inhibition or killing action.
The common ministerial drug of above-mentioned three flavors mutually multiplies each other, can play most important effect to prevention and the treatment of sheep influenza, pestilence.
In the prescription: the Radix Astragali, the bighead atractylodes rhizome, dried orange peel, be adjutant altogether, wherein the Radix Astragali is legume, the sweet lung the spleen channel of returning warm in nature of flavor, has tonifying Qi and lifting yang, benefit is defended solid table function.Cure mainly asthenia of pulmonosplenic qi.The sinking of qi of middle-jiao, hypoimmunity etc., in the Radix Astragali and contain several amino acids, carrotene, folic acid, linoleic acid and 20 various trace elements, higher with calcium, phosphorus, magnesium, iron content, the Radix Astragali also can promote humoral immunity.The bighead atractylodes rhizome is the Cordycepps plant, and bitter is sweet, warm, have tonifying spleen stomach invigorating, eliminating dampness Li Shui, antiabortive, hidroschesis function.Cure mainly: splenasthenic diarrhea, the swollen oedema of tripe etc.Dried orange peel is rutaceae orange.Flavor hot warm in nature, return the lung the spleen channel.Has regulating qi-flowing for strengthening spleen, the dry temperature function of reducing phlegm.Cure mainly that " poor appetite, the stomachache tripe expands, has loose bowels, the productive cough due to phlegm-damp.Above-mentioned three flavor adjutants play sheep and strengthen immunity, somatotrophic effect.
In the prescription: flos caryophylli, fennel seeds, Radix Glycyrrhizae, for making medicine, wherein, flos caryophylli be dry flower, the flavor of plant clove of myrtaceae hot, warm in nature, return spleen, stomach, lung, kidney channel.Have warming middle energizer to descend adverse-rising qi, the warm supporing yang function of kidney.Cure mainly: gastrofrigid vomiting, tripe expand, cold intestines are had loose bowels etc.Fennel seeds be umbellifer drying kind benevolence, the hot levelling temperature of flavor, return, liver, kidney, stomach warp, have eliminating cold to stop pain, the therapeutic method to keep the adverse qi flowing downward and stomach function.Cure mainly: cold intestines are had loose bowels, tripe abdominal distention and pain etc., and have characteristic taste fragrance, flavor little sweet.Radix Glycyrrhizae is legume.Distinguish the flavor of sweet, property is put down, return, the heart, lung, spleen, stomach warp.Have: with the function of middle emergency, coordinating the drug actions of a prescription, cushion toxicity.Cure mainly: weakness of the spleen and the stomach, lassitude, poisoning sore etc.
The all medicine monarchs of above-mentioned prescription, minister, assistant make and respectively take charge of heat-clearing and damp-drying drug, invigorating the spleen to arrest diarrhea, anti-inflammation, enhancing immunity, and raising meat taste etc. is combined into fresh combatants altogether.They multiply each other mutually, mutually restriction, mutually take with, the similarities and differences seek common ground, seeking differences from similarities, thereby to each growth phase of sheep all can play heat-clearing and cold, invigorating the spleen and not dry, anti-inflammatory and do not decrease, smell perfume (or spice) is altered, and is not heavy cold effect.Make and to reach the antibiotic growth promotion of antidiarrheal, meat taste taste bright.
Instructions of taking: medicament of the present invention can be used as the sheep fine fodder and premix material additive long-term, short-term is added and to be fed.Its consumption is:
Young sheep can be added the 3-10 gram every every day in 1 monthly age;
2 monthly age sheep can be added the 10-20 gram every every day;
3 monthly age sheep can be added the 30-50 gram every every day;
Above sheep of 4 monthly ages can be added the 50-80 gram every every day;
Points for attention: this traditional Chinese powder medicine can not dry feeding, needs proportioning fine fodder or premix to add and feeds after proper amount of clear water is mixed thoroughly.
The present invention not yet finds bad reaction through a large amount of clinical testings.
The present invention is through as follows to each monthly age sheep feeding experiment result:
Totally 300 of test sheepshead numbers;
Test period: 60 days, wherein raise in advance 7 days phases;
Test method: be divided at random two groups, test group: above 50 of 50,4 monthly ages at young sheep 50,2 monthly age-3 monthly ages.
Contrast: 50 of young sheep, a 2-3 monthly age more than 50,4 monthly ages 50
Daily ration and daily management are all by the existing rules operation of Yang Chang.
Test group is all added traditional Chinese powder medicine of the present invention by above-mentioned weight ratio.
It is constant that control group is is all prevented and treated method by the original raising in sheep field and antibiotic.
Between the test group feed period, the sheep in three stages at monthly age is without 1 routine injures and deaths, and being full of animal spirits, hair smooth, be of strong physique, grow good.During the control group fed, young sheep causes dead 18, all the other poor growths, poor appetite, listless because of diarrhoea in 1 monthly age.The 2-3 monthly age is suffered from 20 of respiratory disorders.With intramuscular injection or the drug therapy of oral antibiotic class, cure 15, dead 5.4 above 36 of influenzas of suffering from of monthly age.Although controlled death but obvious trichoxerosis with a large amount of antibiotic, listless, poor growth.
Show during two groups of off-tests: the test group number of weaned improves 97%
Diarrhoea decreased average 95% average weight gain 15.8%
Raise tracing observation by all being added medicament of the present invention, during table, use this pharmacy security effective as a result, without 1 routine bad reaction, and be sampled to local Food Inspection department after sheep is butchered and detect delivering for sale, medicament residue is zero.The tracking cold cuts are tasted, and taste has the good to eat delicious food of the pure perfume (or spice) of nature, and this meat gets consumer reception very much.
Patent of the present invention is through using the result to show that following characteristics are arranged:
1, strengthens sheep immunity, improve survival rate; 2, control sheep diarrhea; 3, prevent and treat influenza and pestilence;
4, reduce disease and occur, growth promotion is obvious; 5, abundant, cheap, the safe without toxic side effect in medicine source; 6, improve the meat taste, in the hope of life
The fragrant nonreactive meat of output flavor of fine quality.
The specific embodiment:
Embodiment 1:
2 parts of 10 portions of caulis loniceraes of 10 parts of roots of large-flowered skullcap of 10 portions of elscholtizas of Pogostemon cablin
10 parts of 2 parts of bighead atractylodes rhizomes of 2 parts of Radixs Astragali of 2 parts of capsules of weeping forsythia of dandelion
5 parts in 1 portion of Radix Glycyrrhizae of 0.1 portion of fennel seeds of 2 portions of flos caryophyllis of dried orange peel.
Embodiment 2:
10 parts of 10 portions of caulis loniceraes of 5 parts of roots of large-flowered skullcap of 5 portions of elscholtizas of Pogostemon cablin
5 parts of 5 parts of bighead atractylodes rhizomes of 10 parts of Radixs Astragali of 10 parts of capsules of weeping forsythia of dandelion
8 parts in 2 portions of Radix Glycyrrhizaes of 0.5 portion of fennel seeds of 3 portions of flos caryophyllis of dried orange peel.
Embodiment 3:
15 parts of 8 portions of caulis loniceraes of 3 parts of roots of large-flowered skullcap of 3 portions of elscholtizas of Pogostemon cablin
3 parts of 5 parts of bighead atractylodes rhizomes of 10 parts of Radixs Astragali of 15 parts of capsules of weeping forsythia of dandelion.
Claims (3)
1. be used for strengthening the antiviral foodstuff additive of goat-anti bacterium, it is characterized in that it is to be made by the raw material of following weight proportioning:
。
2. according to claim 1 for strengthening the antiviral foodstuff additive of goat-anti bacterium, it is characterized in that: the weight ratio of described each raw material is:
3. described preparation method for strengthening the antiviral foodstuff additive of goat-anti bacterium is characterized in that it is undertaken by following operation according to claim 1-2:
A, batching: take by weighing the raw material Chinese herbal medicine by consumption;
B, screening: the impurity of removing the raw material Chinese herbal medicine;
C, drying and crushing: each raw material drying is ground into fine powder (No. six sieve) and mixes, the pulvis finished product.
D, packing is up to the standards.
A, batching: take by weighing Chinese herbal medicine by the said ratio consumption;
B, screening: the impurity of removing the raw material medium-height grass;
C, drying and crushing: the Chinese medicine that is up to the standards is taken by weighing and is ground into fine powder, mixes by the double accurate measurement of prescription requirement, powder;
D, compressing grains: the starch and the water-soluble solution that add 2-3 part mix, and are pressed into particle;
Require to carry out weight packaging according to dosage after e, the passed examination.
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| CN2011102156307A CN102894200A (en) | 2011-07-29 | 2011-07-29 | Foodstuff additive used for enhancing sheep antibiosis and anti-virus, and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103549137A (en) * | 2013-11-13 | 2014-02-05 | 易祥 | Antiviral livestock and poultry health care feed additive |
| CN105475645A (en) * | 2016-01-18 | 2016-04-13 | 肖华 | Ecological and health sheep feed additive |
| CN106074776A (en) * | 2016-06-22 | 2016-11-09 | 寿县联众畜牧养殖有限公司 | A kind of herbal mixture medicament for treating sheep diarrhoea |
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| CN101066313A (en) * | 2007-04-23 | 2007-11-07 | 张丛娥 | Chinese medicine prepn for antagonizing bacteria and viruses of pig and improving pork quality and its prepn process |
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| Title |
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| 李黔军等: "中草药饲料添加剂在牛羊生产上的应用研究", 《畜牧与饲料科学》, vol. 30, no. 3, 31 March 2009 (2009-03-31), pages 69 - 70 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103549137A (en) * | 2013-11-13 | 2014-02-05 | 易祥 | Antiviral livestock and poultry health care feed additive |
| CN103549137B (en) * | 2013-11-13 | 2015-09-16 | 易祥 | A kind of antiviral health-care feed for fowls and doemstic animals additive |
| CN105475645A (en) * | 2016-01-18 | 2016-04-13 | 肖华 | Ecological and health sheep feed additive |
| CN106074776A (en) * | 2016-06-22 | 2016-11-09 | 寿县联众畜牧养殖有限公司 | A kind of herbal mixture medicament for treating sheep diarrhoea |
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Application publication date: 20130130 |