CN103585313B - Compound Chinese-western powder for treating fish disease - Google Patents

Compound Chinese-western powder for treating fish disease Download PDF

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CN103585313B
CN103585313B CN201310602131.2A CN201310602131A CN103585313B CN 103585313 B CN103585313 B CN 103585313B CN 201310602131 A CN201310602131 A CN 201310602131A CN 103585313 B CN103585313 B CN 103585313B
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fish
parts
western
vitamin
compound chinese
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CN103585313A (en
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张嗣喜
张子祥
梁小英
张伽祥
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Changde Yongli Sheng Xiang Biotechnology Co., Ltd.
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张嗣喜
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Abstract

The invention provides a compound Chinese-western powder for treating fish disease. The compound Chinese-western powder comprises the following raw materials in part by weight: 15 to 20 parts of acalypha australis, 10 to 15 parts of herba agrimoniae, 9 to 10 parts of rhizoma coptidis, 9 to 10 parts of folium isatidis, 10 to 15 parts of cyrtomium fortunei, 0.005 to 0.01 part of vitamin C, and 0.18 to 0.37 part of transfer factor. The five traditional Chinese herbs in the invention are cooperated tightly and complementarily, and have significant curative effect in smoothly removing viruses of fishes. The western medicines, i.e. vitamin C and the transfer factor, can enhance immunity of fishes, and have remarkable curative effect in treating hemorrhagic disease, enteritis, sepsis and gill rot. The compound Chinese-western powder provided by the invention can be easily absorbed and completely metabolized by fishes, has the advantages of no toxic and side effects, no allergic reaction, no antigenicity, small dosage, quick effect andlong action time, and can solve the problem of abuse and residue of fish-dependent chemical drugs.

Description

A kind of compound recipe Chinese and Western for the treatment of fish diseases is in conjunction with medicated powder
Technical field
The present invention relates to a kind of compound recipe Chinese and Western for the treatment of fish diseases for concrete case in conjunction with medicated powder.
Background technology
Current fishery has unprecedented development, but raiser does not pay attention to environment, causes virus and bacteria to be had an opportunity to take advantage of, makes Fish suffer from various diseases, as sudden hemorrhage, septicemia, sepsis etc.Here single-mindedly detailed annotation is made for sudden hemorrhage.The cause of disease of sudden hemorrhage mainly three kinds: 1, Yersinia ruckeri; 2, gas single-cell bacteria; 3, vibrio.Wherein Yersinia ruckeri is a kind of pathogen being suitable for growth below 20 DEG C, and the optimum time that this bacterium occurs is 3 annual-April, the main bacterium for this reason of pathogen of the Outbreak disease occurred during this; And gas single-cell bacteria and vibrio are warm water type antibacterial, between suitable growth temperature is 20-30 DEG C, therefore, extend to whole high temperature season from late May always, when checking disease fish, all can find this kind of pathogenic bacteria.Above-mentioned three class pathogen all can from ill silver carp, flathead (comprising Carassius aurutus gibelio, white crucian carp), Cyprinus carpio, bream, Ctenopharyngodon idellus and other wild fisheses, and be even separated in mussel, visible cause of disease is not strong to the specificity of host.Ill early stage from visual inspection, the oral cavity of sick fish, abdominal part, the gill cover, eye socket, fin ray and fish body both sides are mild hyperaemia symptom, cut open in abdominal cavity, intestinal and still see a small amount of food.Along with the development of the state of an illness, the congested phenomenon aggravation of above-mentioned body surface, kindred presents bleeding, congested around eye socket, exophthalmos, and abdominal part expands, redness.Cut abdominal cavity open, because internal organs (liver,spleen,kidney etc.) suffer damage, cause abdominal cavity inner product to have the ascites of yellow or redness, liver,spleen,kidney enlargement, intestinal wall is congested, inflation and without food.The greyish white display anemia of the gill, be sometimes purple and swelling, time serious, cheek silk end rots.In 3-April, the body surface inflammation congestive symptom that sick fish occurs is: the positions such as head, mouth, the gill cover, eye socket, and body surface both sides, under abdomeinal fin and the bright place of grade of tail is very, the visible expophthalmos of sick fish had, gill anemia, internal organs are mixed with inflammation in various degree, sometimes also show in intestinal and inflate swelling.Sick fish symptom after May be body surface mainly with gill cover lower edge, fin base and visceral congestion inflammation, oral cavity, kindred also simultaneously congested inflammation sometimes.Owing to occurring more complicated in this sick fish clinical symptoms, symptom not obvious sometimes, fish is both dead, simultaneously the symptom of the sick fish of every bar incomplete same, is therefore difficult to an absolute boundary, so only set about for cause of disease in stage.
The method being used for tackling virus and bacteria at present probably have spray resistance medicine, make virus get rid of external, strengthen autoimmunity etc., wherein spraying resistance medicine can only for a certain virus, and other viruses can cause pathological changes again, can only the respite state of an illness so spray resistance medicine, this is not permanent plan; And only have elder generation that virus is excreted, then strengthen autoimmunity, then change time clear water, the health of such guarantee fish.If use Western medicine to be that master carries out toxin expelling, therapeutic effect is really faster and better, if but with regard to generation drug resistance slowly in permanent use Western medicine fish body, therapeutic effect will be much little, gradually medicine does not just produce great effect, virus and bacteria can get more and more in the body of fish on the contrary, will be more serious during disease relapse.
Summary of the invention
In order to overcome the deficiency that above-mentioned prior art exists, the invention provides a kind of compound recipe Chinese and Western for the treatment of fish diseases in conjunction with medicated powder, this medicated powder can treat the diseases such as Fish fulminant hemorrhagic disease, septicemia, gill rot, and can improve fish body immunity, drug resistance is not produced to Fish, without any side effects.
Technical scheme of the present invention is to provide a kind of compound recipe Chinese and Western for the treatment of fish diseases in conjunction with medicated powder, comprises the raw material of following parts by weight: Acalypha australis 15-20, Radix Agrimoniae 10-15, chicken feet Rhizoma Coptidis 9-10, Folium Isatidis 9-10, Rhizoma Osmundae 10-15, vitamin C 0.005-0.01, transfer factor 0.18-0.37.
The parts by weight of above-mentioned each raw material are preferably Acalypha australis 20, Radix Agrimoniae 15, chicken feet Rhizoma Coptidis 10, Folium Isatidis 10, Rhizoma Osmundae 15, vitamin C 0.007, transfer factor 0.26.
During making, by above-mentioned parts by weight take clean and dried Acalypha australis, Radix Agrimoniae, chicken feet Rhizoma Coptidis, Folium Isatidis, Rhizoma Osmundae, and roll to be pulverized and mixed through machine together with vitamin C, transfer factor and form.
It is auxiliary that the present invention takes Western medicine as the leading factor with Chinese medicine, so Chinese medicine accounts for main component.Acalypha australis, Agrimony, chicken feet Rhizoma Coptidis, Folium Isatidis, the Chinese medicine such as Rhizoma Osmundae coordinates compact, determined curative effect, complements one another, and can get rid of fishes virus smoothly.Vitamin C, transfer factor then can improve the immunity of Fish self.Medicated powder of the present invention can realize first being discharged in fish body by fishes virus antibacterial, then improves the autoimmunity of Fish, thoroughly the disease such as fulminant hemorrhagic disease, septicemia, gill rot for the treatment of Fish.
In the present invention, Acalypha australis is monarch drug, bitter and puckery flavor, heat-clearing and toxic substances removing, dampness removing, astringing to arrest bleeding, for enteritis, dysentery, haematemesis, epistaxis, have blood in stool, hematuria, metrorrhagia, external treatment carbuncle furuncle infections, dermatitis and eczema.Radix Agrimoniae, JIZHUANHUANG are linked as ministerial drug, and wherein Agrimony is epistasis astringing to arrest bleeding, diarrhea, have heart tonifying, blood coagulation, hemostasis, removing heat from blood, the effect such as antibacterial, for various hemorrhage, haematemesis, hematuria, have blood in stool, metrorrhagia, click blood, epistaxis, dysentery; Chicken feet Rhizoma Coptidis, bitter cold, GUIXIN, taste liver and gall, large intestine channel, cures mainly heat clearing and damp drying, eliminating fire and detoxication, dispersing the stagnated liver-QI for regulating the stomach preventing or arresting vomiting, and also have stronger bactericidal action, to three burnt excess-fires, scorching, heat in blood tells nosebleed, dysentery, carbuncle pyogenic infections from tumour or sore, and eczema, therapeutical effect is obvious.Folium Isatidis and Rhizoma Osmundae are for making medicine, wherein Folium Isatidis is mainly used in pyretic toxicity and sends out the diseases such as speckle, erysipelas, laryngopharynx swelling and pain, aphtha of the mouth and tongue, sore and toxic, for causing bleeding property of antibacterial septicemia, gill rot, hard squama, rotten disorders of blood, hemorrhagic disease, there is therapeutical effect, tool clinical experiment is improved the Scavenging activity of fish body to oxygen-derived free radicals, alleviates fish body and suffers free radical to attack caused damage; Rhizoma Osmundae bitter in the mouth is slightly cold, main enter Liver Channel, have the merit of cooling blood for hemostasis, cure mainly the caused haematemesis of heat in blood, have blood in stool, the disease such as metrorrhagia, especially kindly control metrostaxis, can the excess-heat that divides of clearing heat in QI system, can separate again the pyretic toxicity of blood system, the disease caused by all warm poison are evil all can use it.And vitamin C is for preventing vitamin C deficiency, to the auxiliary treatment of various infectious disease, regulating the internal recycle of fish body, thus reaching the effect of co-treatment; Transfer factor has immunology widely and regulates active, can activate by inducing immune cells on the one hand, enhancing body non-specific immunity, specific immunity ability can be delivered to other animals on the other hand, excites animal to produce specific immunity.
Advantage of the present invention is: Chinese medicine of the five flavours in the present invention coordinates compact, determined curative effect, complements one another, fishes virus can be got rid of smoothly, Western medicine vitamin C, transfer factor then can improve the immunity of Fish self, evident in efficacy to hemorrhagic disease, enteritis, deteriorated blood, gill rot.This fish medicine is easily absorbed and fully metabolism by fish body, has no side effect simultaneously, and without anaphylaxis, no antigen, using dosage is little, rapid-action, and duration of efficacy is long, can solve abuse and residue problem that Fish rely on chemicals.
Detailed description of the invention
Now in conjunction with specific embodiments, technology contents of the present invention is further described.
Embodiment 1
Take by weight cleaned and dried Acalypha australis 20kg, Radix Agrimoniae 15kg, chicken feet Rhizoma Coptidis 10kg, Folium Isatidis 9kg, Rhizoma Osmundae 15 kg, and roll to be pulverized and mixed through machine together with 10g vitamin C, 370g transfer factor and form.
Embodiment 2
Take by weight cleaned and dried Acalypha australis 20kg, Radix Agrimoniae 15kg, chicken feet Rhizoma Coptidis 10kg, Folium Isatidis 10kg, Rhizoma Osmundae 15 kg, and roll to be pulverized and mixed through machine together with 7g vitamin C, 260g transfer factor and form.
Embodiment 3
Take by weight cleaned and dried Acalypha australis 15kg, Radix Agrimoniae 10kg, chicken feet Rhizoma Coptidis 9kg, Folium Isatidis 10kg, Rhizoma Osmundae 10 kg, and roll to be pulverized and mixed through machine together with 5g vitamin C, 180g transfer factor and form.
Through experimental observation Fish gill rot, hemorrhage, diarrhoea, the traditional Chinese medical science thinks all relevant with liver, lung, stomach, intestinal, hemorrhagic disease is all about 6-JIUYUE, heat, accumulation of heat is in interior, pyretic toxicity impairing the liver, pathogenic fire derived from stagnation of liver-QI, burning hot punishment gold, lung lose Xuan Fabian and cause upper respiratory tract infection (gill rot class), liver enlargement.Pyretic toxicity excretion is unable, on disturb in lung, impairment of purifying and descending function of the lung, lung moves heat in intestinal, injures fat network, and cause suffering from diarrhoea and saying of having blood in stool, pyretic toxicity is invaded in blood, causes systemic toxicity profiles phenomenon just to cause hemorrhage even dead.Be below the test of several embody rule:
Test A: western Dongting Lake five branch eight team, householder Zhang Jiafu supports 60 mu, the fishing pond depth of water one meter five, the diseases such as disorders of blood, gill rot, enteritis are broken in August, 2013, dead about 300 jin of general every day, householder just repeatedly uses other fish medicines invalid, after going and finding out what's going on, carry out the actual dispensing test of this product, test procedure is as follows: first day is got ten jin and stirred with 250 grams of fish medicines of the present invention from 100 jin of feedstuffs, first drop in lake, all the other 90 jin are not added any impurity or medicine, after throw something and feed, sooner or later respectively once, then this medicine feed is carried out three days.Dose minimizing is carried out after improving situation, stir with 200 grams of fish medicines of the present invention with extracting ten jin in 100 jin of feedstuffs, first drop in lake, all the other 90 jin are not added any impurity or medicine, after throw something and feed, once a day, this medicine feed mode carries out two days, five days is a course for the treatment of, has the observation period of 15 days, do not occur exception after drug withdrawal.
Experiment B: Long Tian village of Jin Feng office, western Dongting Lake, householder Xu Hong supports 30 mu, the fishing pond depth of water two meter five, the disease such as disorders of blood, gill rot is broken in July, 2013, dead about 200 jin of general every day, householder just repeatedly uses other fish medicines invalid, after going and finding out what's going on, carry out the actual dispensing experiment of this product, test procedure is as follows: first day stirs with 250 grams of fish medicines of the present invention with extracting ten jin in 100 jin of feedstuffs, first drop in lake, all the other 90 jin are not added any impurity or medicine, after throw something and feed, sooner or later respectively once, then this medicine feed is carried out three days.Dose minimizing is carried out after improving situation, stir with 200 grams of fish medicines of the present invention with extracting ten jin in 100 jin of feedstuffs, first drop in lake, all the other 90 jin are not added any impurity or medicine, after throw something and feed, once a day, then this medicine feed mode is carried out two days, five days is a course for the treatment of, has the observation period of 15 days, do not occur exception after drug withdrawal.
Experiment C: around western Dongting Lake Jin Feng tri-village, 20 mu, the householder Zhou Weiyu pond depth of water one meter five, the diseases such as disorders of blood, gill rot, enteritis are broken in August, 2013, dead about 100 jin of general every day, householder just repeatedly uses other fish medicines invalid, after going and finding out what's going on, carry out the actual dispensing experiment of this product, experimental procedure is as follows: first day stirs with 250 grams of fish medicines of the present invention with extracting ten jin in 100 jin of feedstuffs, first drop in lake, all the other 90 jin are not added any impurity or medicine, after throw something and feed, sooner or later respectively once, then this medicine feed is carried out three days.Dose minimizing is carried out after improving situation, stir with 200 grams of fish medicines of the present invention with extracting ten jin in 100 jin of feedstuffs, first drop in lake, all the other 90 jin are not added any impurity or medicine, after throw something and feed, once a day, then this medicine feed mode is carried out two days, five days is a course for the treatment of, has the observation period of 15 days, do not occur exception after drug withdrawal.
The following form of result of the test of three testing sites:
(note: following data are the weight of dead fish after medication)

Claims (2)

1. the compound recipe Chinese and Western for the treatment of fish diseases, in conjunction with a medicated powder, is characterized in that being made up of the raw material of following parts by weight: Acalypha australis 15-20, Radix Agrimoniae 10-15, chicken feet Rhizoma Coptidis 9-10, Folium Isatidis 9-10, Rhizoma Osmundae 10-15, vitamin C 0.005-0.01, transfer factor 0.18-0.37.
2. the compound recipe Chinese and Western for the treatment of fish diseases according to claim 1 is in conjunction with medicated powder, it is characterized in that: the parts by weight of described each raw material are preferably Acalypha australis 20, Radix Agrimoniae 15, chicken feet Rhizoma Coptidis 10, Folium Isatidis 10, Rhizoma Osmundae 15, vitamin C 0.007, transfer factor 0.26.
CN201310602131.2A 2013-11-26 2013-11-26 Compound Chinese-western powder for treating fish disease Active CN103585313B (en)

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CN103861069B (en) * 2014-03-11 2016-06-22 昆明理工大学 A kind of humate compound recipe fish medicine and preparation method
CN104688856A (en) * 2015-03-31 2015-06-10 苏远芳 Medicine for treating fish diseases

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CN101721616A (en) * 2008-10-22 2010-06-09 宋正飞 Medicine for stopping bleeding
CN101757149A (en) * 2008-10-30 2010-06-30 天津生机集团股份有限公司 Pure Chinese herbal compound medicine for preventing fish hemorrhage

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Effective date of registration: 20190530

Address after: 415137 Three Villagers Group of Tianfu Village, Zhufeng Town, West Dongting, Changde City, Hunan Province

Patentee after: Changde Yongli Sheng Xiang Biotechnology Co., Ltd.

Address before: 415137 Tianfu Village 3 Villagers Group, Zhufeng Town, West Dongting District, Dingcheng District, Changde City, Hunan Province

Patentee before: Zhang Sixi

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