CN101048493B - 细胞组织微芯片及细胞组织的形成方法 - Google Patents

细胞组织微芯片及细胞组织的形成方法 Download PDF

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CN101048493B
CN101048493B CN2005800367166A CN200580036716A CN101048493B CN 101048493 B CN101048493 B CN 101048493B CN 2005800367166 A CN2005800367166 A CN 2005800367166A CN 200580036716 A CN200580036716 A CN 200580036716A CN 101048493 B CN101048493 B CN 101048493B
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cell
cells
adhesive
tissue
microchip
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CN101048493A (zh
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中泽浩二
福田淳二
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Kitakyushu Foundation for Advancement of Industry Science and Technology
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CN2005800367166A 2004-10-29 2005-10-21 细胞组织微芯片及细胞组织的形成方法 Expired - Fee Related CN101048493B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004315600A JP3981929B2 (ja) 2004-10-29 2004-10-29 細胞組織体マイクロチップ
JP315600/2004 2004-10-29
PCT/JP2005/019427 WO2006046490A1 (ja) 2004-10-29 2005-10-21 細胞組織体マイクロチップ及び細胞組織体の形成方法

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CN101048493A CN101048493A (zh) 2007-10-03
CN101048493B true CN101048493B (zh) 2012-07-18

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US (1) US8652847B2 (enExample)
EP (1) EP1806394B1 (enExample)
JP (1) JP3981929B2 (enExample)
KR (1) KR100877306B1 (enExample)
CN (1) CN101048493B (enExample)
DE (1) DE602005017924D1 (enExample)
WO (1) WO2006046490A1 (enExample)

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JP4033265B2 (ja) * 2004-10-29 2008-01-16 財団法人北九州産業学術推進機構 細胞組織体マイクロデバイス
US9121003B2 (en) 2007-09-12 2015-09-01 Kitakyushu Foundation For The Advancement Of Industry, Science And Technology Cell culture instrument and cell culture method using the same
KR20140069360A (ko) * 2009-06-23 2014-06-09 가부시키가이샤 히타치세이사쿠쇼 배양 기재
JP5730472B2 (ja) * 2009-06-23 2015-06-10 株式会社日立製作所 培養基材、及び細胞培養方法
JP5730499B2 (ja) * 2010-05-07 2015-06-10 株式会社日立製作所 培養器材
JP5688695B2 (ja) * 2010-01-29 2015-03-25 独立行政法人理化学研究所 基板、細胞培養装置、細胞チップおよび培養方法
CN103261393A (zh) * 2010-12-22 2013-08-21 株式会社日立制作所 培养器材以及培养片材
WO2014061675A1 (ja) * 2012-10-17 2014-04-24 コニカミノルタ株式会社 希少細胞の回収方法および検出方法
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
US20160369217A1 (en) * 2014-02-05 2016-12-22 Toyo Gosei Co., Ltd. Plates for culture of biological samples
JP2017532971A (ja) 2014-10-29 2017-11-09 コーニング インコーポレイテッド 細胞培養集合体を生成するためのマイクロウェル設計および製造
JP6930914B2 (ja) 2014-10-29 2021-09-01 コーニング インコーポレイテッド 灌流バイオリアクタ・プラットフォーム
JP6731916B2 (ja) 2014-10-29 2020-07-29 コーニング インコーポレイテッド 細胞培養インサート
JP5909543B2 (ja) * 2014-12-26 2016-04-26 株式会社日立製作所 培養器材
JP5984998B2 (ja) * 2015-04-08 2016-09-06 株式会社日立製作所 培養基材
CN104774763A (zh) * 2015-04-24 2015-07-15 何向锋 一种微片式单细胞克隆分离培养板及单细胞克隆分离方法
CN109126912B (zh) * 2017-06-15 2021-02-02 上海微创医疗器械（集团）有限公司 生物芯片及其制备方法
PL3652292T3 (pl) 2017-07-14 2025-09-01 Corning Incorporated Naczynie do hodowli komórkowej 3d i sposoby hodowli komórkowej 3d
CN111051494B (zh) 2017-07-14 2024-03-29 康宁股份有限公司 用于手动或自动培养基交换的3d细胞培养容器
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
AU2019302182A1 (en) 2018-07-10 2021-03-04 Nippon Shokubai Co., Ltd. Cell culture sheet
CN111065725B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 包括具有互联的壁的微板的流体装置
EP3649229B1 (en) 2018-07-13 2021-08-25 Corning Incorporated Cell culture vessels with stabilizer devices
US11912968B2 (en) 2018-07-13 2024-02-27 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
CN113278523B (zh) * 2021-05-08 2024-11-15 上海碧博生物医药工程有限公司 具有细胞定位功能的细胞培养板及其制备方法和细胞定位的方法
EP4289934B1 (en) * 2022-06-09 2025-12-31 Finnadvance Oy CELL CULTURE MEMBRANE STRUCTURE, ITS PRODUCTION PROCESSES, CELL CULTURE PLATE, CELL CULTURE APPARATUS INCLUDING THE CELL CULTURE MEMBRANE STRUCTURE AND CELL CULTURE PROCESSES USING THE CELL CULTURE APPARATUS

Citations (2)

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CN1490400A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 毛细管微包被法控制细胞空间分布、形状和大小及其应用
CN1490401A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 低自由能表面微处理控制细胞空间定位及应用

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US5202227A (en) 1989-06-03 1993-04-13 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Control of cell arrangement
JP3887435B2 (ja) 1996-07-12 2007-02-28 第一製薬株式会社 スフェロイド形成促進剤
WO2002004113A2 (en) * 2000-07-11 2002-01-17 The Johns Hopkins University School Of Medicine Methods of patterning protein and cell adhesivity
JP4002720B2 (ja) * 2000-11-22 2007-11-07 独立行政法人科学技術振興機構 一細胞長期培養顕微観察装置
JP2002357604A (ja) * 2001-04-17 2002-12-13 Nisshinbo Ind Inc 反応容器及びこれを用いる生物学的に活性な物質の分析方法
AU2002257289A1 (en) 2001-05-17 2002-11-25 The Board Of Trustees Of The Leland Stanford Junior University Device and method for three-dimensional spatial localization and functional interconnection of different types of cells
AU2002352696A1 (en) 2001-11-16 2003-06-10 University Of North Carolina At Chapel Hill Cell substrates and methods of use thereof

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1490400A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 毛细管微包被法控制细胞空间分布、形状和大小及其应用
CN1490401A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 低自由能表面微处理控制细胞空间定位及应用

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Publication number Publication date
CN101048493A (zh) 2007-10-03
KR100877306B1 (ko) 2009-01-07
WO2006046490A1 (ja) 2006-05-04
EP1806394A4 (en) 2008-10-22
EP1806394A1 (en) 2007-07-11
EP1806394B1 (en) 2009-11-25
US8652847B2 (en) 2014-02-18
JP3981929B2 (ja) 2007-09-26
US20080138900A1 (en) 2008-06-12
JP2006121991A (ja) 2006-05-18
KR20070065905A (ko) 2007-06-25
DE602005017924D1 (de) 2010-01-07

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Address after: Fukuoka Prefecture

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