CL2012000061A1 - Composición oftálmica acuosa estéril que comprende un copolímero de bloque de óxido de etileno óxido de butileno (eo-bo) y una galactomanana; y uso para el tratamiento del ojo seco. - Google Patents

Composición oftálmica acuosa estéril que comprende un copolímero de bloque de óxido de etileno óxido de butileno (eo-bo) y una galactomanana; y uso para el tratamiento del ojo seco.

Info

Publication number
CL2012000061A1
CL2012000061A1 CL2012000061A CL2012000061A CL2012000061A1 CL 2012000061 A1 CL2012000061 A1 CL 2012000061A1 CL 2012000061 A CL2012000061 A CL 2012000061A CL 2012000061 A CL2012000061 A CL 2012000061A CL 2012000061 A1 CL2012000061 A1 CL 2012000061A1
Authority
CL
Chile
Prior art keywords
galactomannan
block copolymer
sterile aqueous
ophthalmic composition
treatment
Prior art date
Application number
CL2012000061A
Other languages
English (en)
Spanish (es)
Inventor
James W Davis
Howard Allen Ketelson
David L Meadows
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of CL2012000061A1 publication Critical patent/CL2012000061A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/77Polymers containing oxygen of oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/008Polymeric surface-active agents
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/20Organic compounds containing oxygen
    • C11D3/22Carbohydrates or derivatives thereof
    • C11D3/222Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eyeglasses (AREA)
CL2012000061A 2009-07-07 2012-01-09 Composición oftálmica acuosa estéril que comprende un copolímero de bloque de óxido de etileno óxido de butileno (eo-bo) y una galactomanana; y uso para el tratamiento del ojo seco. CL2012000061A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22359909P 2009-07-07 2009-07-07

Publications (1)

Publication Number Publication Date
CL2012000061A1 true CL2012000061A1 (es) 2012-10-19

Family

ID=43427630

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012000061A CL2012000061A1 (es) 2009-07-07 2012-01-09 Composición oftálmica acuosa estéril que comprende un copolímero de bloque de óxido de etileno óxido de butileno (eo-bo) y una galactomanana; y uso para el tratamiento del ojo seco.

Country Status (15)

Country Link
US (1) US9175249B2 (https=)
EP (1) EP2451463B1 (https=)
JP (1) JP5791600B2 (https=)
KR (1) KR101246243B1 (https=)
CN (1) CN102548561B (https=)
AR (1) AR077458A1 (https=)
AU (1) AU2010270628B2 (https=)
BR (1) BR112012000506A2 (https=)
CA (1) CA2767459C (https=)
CL (1) CL2012000061A1 (https=)
MX (1) MX2012000456A (https=)
RU (1) RU2548789C2 (https=)
TW (1) TWI547522B (https=)
WO (1) WO2011005864A2 (https=)
ZA (1) ZA201200255B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2919755T3 (pl) * 2012-11-19 2018-07-31 Bausch & Lomb Incorporated Wodna ciekła kompozycja zawierająca kwas 2-amino-3-(4-bromobenzoilo)fenylooctowy
WO2015048223A2 (en) * 2013-09-27 2015-04-02 Novartis Ag Compositions and methods for disinfecting and cleaning contact lenses
US9987581B2 (en) 2015-06-22 2018-06-05 Agco International Gmbh Vehicle filter system
CA3034608A1 (en) * 2016-08-24 2018-03-01 The University Of Melbourne Diagnostic methods and device

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2174761A (en) * 1935-04-13 1939-10-03 Ig Farbenindustrie Ag Condensation products derived from hydroxy compounds and method of producing them
GB722746A (en) 1952-06-24 1955-01-26 Wyandotte Chemicals Corp Surface active compounds derived from higher ª‡, ª‰ alkylene oxides
US2674619A (en) * 1953-10-19 1954-04-06 Wyandotte Chemicals Corp Polyoxyalkylene compounds
US2828345A (en) * 1955-04-27 1958-03-25 Dow Chemical Co Hydroxypolyoxyethylene diethers of polyoxybutylene glycols
US3050511A (en) * 1958-09-15 1962-08-21 Dow Chemical Co Block copolymers of alkenyl aromatic hydrocarbons and alkylene oxides
US3042668A (en) * 1960-12-02 1962-07-03 American Molasses Company Modified galactomannan gums and method of preparing same
US3829506A (en) * 1971-06-01 1974-08-13 Basf Wyandotte Corp Biodegradable surface active agents having good foam properties and foam stabilizing characteristics
US4130517A (en) * 1973-01-29 1978-12-19 Exxon Research & Engineering Co. Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
CA1043039A (en) * 1973-01-29 1978-11-21 Robert D. Lundberg Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
US4104824A (en) * 1975-02-27 1978-08-08 Exxon Research & Engineering Co. Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
US4218327A (en) * 1976-04-05 1980-08-19 Shell Oil Company Stabilizing the viscosity of an aqueous solution of polysaccharide polymer
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
JPS5594901A (en) 1979-01-11 1980-07-18 Nichiden Kagaku Kk Preparation of modified guar gum
US4360451A (en) * 1981-08-10 1982-11-23 Basf Wyandotte Corporation Amphoteric surfactant gels
US4447336A (en) * 1981-12-18 1984-05-08 Monsanto Company Stabilized galactomannan gum compositions
US4447337A (en) * 1982-02-24 1984-05-08 Monsanto Company Stabiized galactomannan gum compositions
US4606831A (en) 1985-06-17 1986-08-19 Monsanto Company Stabilized galactomannan gum compositions
SE458576B (sv) * 1985-06-20 1989-04-17 Lejus Medical Ab Foerfarande foer framstaellning av en guar-gum produkt
JPS6335606A (ja) 1986-07-30 1988-02-16 Mitsubishi Acetate Co Ltd ガラクトマンナンの精製方法
JPS63101402A (ja) 1986-10-17 1988-05-06 Mitsubishi Acetate Co Ltd ガラクトマンナンの精製法
DE3701509A1 (de) 1987-01-21 1988-08-04 Henkel Kgaa Verfahren zur herstellung von guar-(misch-)ethern aus guarsplits
PT89126B (pt) * 1987-12-02 1993-09-30 Colgate Palmolive Co Processo para a preparacao de uma composicao de limpeza suave e de condicionamento para amaciamento da pele, contendo baixos niveis de um agente tensio-activo nao ionico e um acido organico
JPH01247049A (ja) 1988-03-29 1989-10-02 Sumitomo Chem Co Ltd 溶解性の改良されたガラクトマンナンの製造法
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
WO1990003406A1 (en) * 1988-09-22 1990-04-05 University Of Utah Polymer supersurfactants for protein resistance and protein removal
US5233032A (en) * 1990-06-29 1993-08-03 Stein, Hall & Co., Inc. Hydrophobically modified hydroxybutyl ethers of polygalactomannan
US5346703A (en) * 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
US5077033A (en) * 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US5376693A (en) * 1990-08-07 1994-12-27 Mediventures Inc. Thermo-irreversible gel corneal contact lens formed in situ
JPH08842B2 (ja) * 1991-05-22 1996-01-10 信越化学工業株式会社 多糖類の精製方法
EP0557627A1 (en) 1992-02-24 1993-09-01 TAIYO KAGAKU Co., LTD. Limitedly enzyme-hydrolyzed polysaccharide and method for its production
JPH05239105A (ja) 1992-03-02 1993-09-17 Mitsubishi Rayon Co Ltd 精製ガラクトマンナンの製造方法
JP2729722B2 (ja) 1992-03-02 1998-03-18 三菱レイヨン株式会社 精製ガラクトマンナンの製造方法
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
ATE300936T1 (de) * 1992-05-06 2005-08-15 Alcon Lab Inc Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
KR100342089B1 (ko) * 1993-06-18 2002-11-23 폴리머 테크놀로지 코포레이션 콘택트렌즈 세정 및 습윤화용 조성물
US5370744B1 (en) * 1993-08-27 1999-11-09 Alcon Lab Inc Process for cleaning and disinfecting contact lenses
US5631005A (en) * 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5489674A (en) * 1994-06-09 1996-02-06 Rhone-Poulenc Inc. Guar gum composition and process for making it
US5536825A (en) * 1994-06-09 1996-07-16 Rhone-Poulenc Inc. Derivatized guar gum composition and process for making it
ATE201883T1 (de) 1994-06-09 2001-06-15 Rhodia Guargummizusammensetzung und verfahren zur deren herstellung
ES2163462T3 (es) * 1994-08-22 2002-02-01 Kao Corp Composicion detergente para superficie dura.
US5602241A (en) 1995-03-14 1997-02-11 Shin-Etsu Chemical Co., Ltd. Method for purifying polysaccharides
US6063402A (en) * 1995-06-07 2000-05-16 Venture Lending, A Division Of Cupertino National Bank Purified galactomannan as an improved pharmaceutical excipient
CH691026A5 (de) 1995-09-28 2001-04-12 Meyhall Chemical Ag Rhone Poul Verfahren zur Herstellung von reinem Guarkernmehl.
WO1997016408A1 (de) * 1995-10-27 1997-05-09 Basf Aktiengesellschaft Fettsäurederivate und ihre verwendung als tenside in wasch- und reinigungsmitteln
JP4030603B2 (ja) * 1995-11-02 2008-01-09 ノボザイムス アクティーゼルスカブ アルカリプロテアーゼ、その製造方法、用途及びそのプロテアーゼを生産する微生物
WO1997025354A1 (en) 1996-01-05 1997-07-17 Rhone-Poulenc Inc. Modified guar, prepared by high shear treatment under acidic conditions at elevated temperature
US5756720A (en) * 1996-10-25 1998-05-26 Rhodia Inc. Derivatized guar gum composition including nonionic and cationic groups which demonstrate excellent solution clarity properties
DK0934343T3 (da) 1996-10-25 2003-04-28 Rhodia Afledt guargummisammensætning indbefattende non-ioniske og kationiske grupper, der udviser enestående egenskaber til klaring af opløsninger til brug som rengøringsmidler
WO1998025649A1 (en) * 1996-12-13 1998-06-18 Alcon Laboratories, Inc. Use of low molecular weight amino alcohols in ophthalmic compositions
US6214596B1 (en) * 1996-12-18 2001-04-10 Alcon Laboratories, Inc. Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5997907A (en) 1997-03-12 1999-12-07 Rhodia Inc. Enhancement of guar solution stability
DK1203808T3 (da) 1997-07-29 2005-01-31 Alcon Lab Inc Konditioneringsoplösninger til pleje af hårde kontaktlinser
DE69839355T2 (de) 1997-07-29 2009-06-04 Alcon Laboratories, Inc., Fort Worth Ophthalmische Zusammensetzungen enthaltend Galaktomannanpolymere und Borat
ZA9811445B (en) * 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
US6656504B1 (en) * 1999-09-09 2003-12-02 Elan Pharma International Ltd. Nanoparticulate compositions comprising amorphous cyclosporine and methods of making and using such compositions
MY128134A (en) * 2000-09-28 2007-01-31 Novartis Ag Compositions and methods for cleaning contact lenses
ES2331302T3 (es) * 2001-05-01 2009-12-29 A.V. Topchiev Institute Of Petrochemical Synthesis Composiciones de hidrogel.
DE10135060A1 (de) 2001-07-18 2003-02-06 Noveon Ip Holdings Corp Galactomannan mit verändertem Mannose zu Galactose Verhältnis
TW200300448A (en) 2001-11-21 2003-06-01 Novartis Ag Conditioning solution for contact lenses
DE10241878A1 (de) * 2002-09-10 2004-03-11 Ecolab Gmbh & Co. Ohg Reinigung von Fahrzeugen
US20040241130A1 (en) * 2002-09-13 2004-12-02 Krishnan Tamareselvy Multi-purpose polymers, methods and compositions
US7378479B2 (en) * 2002-09-13 2008-05-27 Lubrizol Advanced Materials, Inc. Multi-purpose polymers, methods and compositions
ITTO20020809A1 (it) * 2002-09-17 2004-03-18 St Microelectronics Srl Micropompa, in particolare per un dispositivo integrato di analisi del dna.
TW200503762A (en) 2003-05-09 2005-02-01 Toho Chem Ind Co Ltd Cation-modified galactomannan polysaccharide and cosmetic composition containing the same
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7195065B2 (en) * 2004-08-05 2007-03-27 Baker Hughes Incorporated Stabilizing crosslinked polymer guars and modified guar derivatives
US7629386B2 (en) * 2004-08-26 2009-12-08 Bausch + Lomb Incorporated Compositions containing trialkanolamine alkoxylate buffer
RU2285511C2 (ru) * 2004-10-13 2006-10-20 НИИ ГБ им. Гельмгольца Средство для лечения синдрома сухого глаза
US20060229219A1 (en) * 2005-04-11 2006-10-12 Advanced Medical Optics, Inc. Borate-polyol mixtures as a buffering system
US7282178B2 (en) * 2005-06-03 2007-10-16 Bausch & Lomb Incorporated Composition and method for cleaning lipid deposits on contact lenses
TWI434926B (zh) 2006-12-11 2014-04-21 Alcon Res Ltd 眼用組成物中聚氧化乙烯-聚氧化丁烯(peo-pbo)嵌段共聚物之使用
AR066901A1 (es) 2007-05-18 2009-09-23 Alcon Mfg Ltd Composiciones fodfolipidicas para elcuidado de lentes de contacto y conservacion de composiciones farmaceuticas
US20090132294A1 (en) * 2007-11-15 2009-05-21 Haines Samuel H Method for ranking driver's relative risk based on reported driving incidents
BRPI0910717A2 (pt) 2008-04-26 2015-09-29 Alcon Res Ltd sistema polimérico de lágrima artificial
AR073574A1 (es) 2008-09-10 2010-11-17 Alcon Res Ltd Inhibidores heterociclicos de los receptores de histamina para el tratamiento de una enfermedad

Also Published As

Publication number Publication date
AU2010270628A1 (en) 2012-02-02
CA2767459C (en) 2018-04-10
AR077458A1 (es) 2011-08-31
RU2012103982A (ru) 2013-08-20
JP5791600B2 (ja) 2015-10-07
CN102548561A (zh) 2012-07-04
US20110008276A1 (en) 2011-01-13
JP2012532878A (ja) 2012-12-20
MX2012000456A (es) 2012-02-28
ZA201200255B (en) 2013-03-27
WO2011005864A2 (en) 2011-01-13
CN102548561B (zh) 2016-03-16
TW201107414A (en) 2011-03-01
WO2011005864A3 (en) 2011-04-28
KR101246243B1 (ko) 2013-03-22
TWI547522B (zh) 2016-09-01
RU2548789C2 (ru) 2015-04-20
KR20120028994A (ko) 2012-03-23
EP2451463A2 (en) 2012-05-16
US9175249B2 (en) 2015-11-03
BR112012000506A2 (pt) 2017-05-16
AU2010270628B2 (en) 2013-12-19
CA2767459A1 (en) 2011-01-13
EP2451463B1 (en) 2018-11-07

Similar Documents

Publication Publication Date Title
AR062046A1 (es) Soluciones oftalmicas
MX2009009463A (es) Preparacion de una pelicula de rapida disolucion/desintegracion que tiene una alta proporcion de ingrediente activo.
CL2008003406A1 (es) Compuestos derivados de quinolina; composicion farmaceutica que los comprende; y uso en el tratamiento de una infeccion por vih.
CL2012001583A1 (es) Preparación oftálmica que comprende: a) povidona yodada, b) un agente refrescante y c) uno o más entre alcanfor, borneol, lubricante, emoliente, antiinflamatorio esteroidal y antinflamatorio no esteroidal; y su uso para el tratamiento y/o profilaxis de un trastorno ocular o una infección.
UY33984A (es) Uso de 2,3-dihidroimidazo [1,2-c] quinazolinas sustituidas
CL2011000170A1 (es) Composicion farmaceutica solida y estabilizada que comprende un ingrediente farmaceuticamente activo, oxido de titanio y un plastificante; procedimiento para estabilizar la composicion farmaceutica durante una irradiacion luminosa.
CL2016001041A1 (es) Implante intraocular biodegradable que contiene una matriz de polimero biodegradable, polietilenglicol 3350 y una prostamida; uso del mismo en la reducción de la presion ocular en el ojo de un mamifero; aparato para administrar el implante intraocular biodegradable; y método para confeccionar un implante intraocular biodegradable.
CL2011003266A1 (es) Compuestos derivados de imidazolidin-2-ona, con actividad inhibidora de 17alfa-hidroxilasa/liasa-c17,20; composicion farmaceutica que los comprende; y uso en el tratamiento de inflamacion o cancer, entre otras.
CL2011002700A1 (es) Marcador de eventos ingerible altamente confiable y metodo para el uso del mismo.
BRPI0714399B8 (pt) composição farmacêutica líquida oral
CO6541645A2 (es) Compuestos de indol y su uso farmaceutico
CL2013000715A1 (es) Composicion farmaceutica que comprende (3s,11ar)-n-[(2,4-difluorofenil)metil]-2,3,5,7,11,11a-hexahidro-6-hidroxi-3-metil-5,7-dioxo-oxazolo[3,2-a]pirido[1,2-d]pirazin-8-carboxamida y un sistema de agente tensoactivo de polisorbato y polietilenglicol; metodo de tratamiento; y su uso para tratar o prevenir una infeccion por vih.
AR060580A1 (es) Elastomeros de silicona que contienen antisepticos
CL2008001498A1 (es) Uso de un anticuerpo contra el factor d en la prevencion o tratamiento de una condicion ocular asociada al complemento.
CL2012002355A1 (es) Compuestos derivados de 1,3,4,8-tetrahidro-2h-pirido[1,2-a]pirazina; composicion farmaceutica que los comprende; kit farmaceutico; y su uso como inhibidores de la integrasa del vih para el tratamiento de una enfermedad infecciosa del vih.
CL2012002733A1 (es) Compuestos derivados de ácido 1-amino-2-ciclopropiletilborónico, inhibidores de proteasoma; composición farmacéutica; uso en el tratamiento del cáncer; procedimiento de preparacion; compuestos intermediarios.
CL2008003405A1 (es) Compuestos derivados de tienopiridina, inhibidores de la enzima integrasa del vih; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una infeccion por vih.
MX2015009772A (es) Moduladores de receptores nmda de espiro-lactama y sus usos.
UY32819A (es) Composiciones farmaceuticas de uso oftalmico de antagonistas del receptor dp2
AR089336A1 (es) Composiciones para el cuidado oral
CL2011003327A1 (es) Composicion farmaceutica que comprende finafloxacina y un agente antiinflamatorio; uso en el tratamiento de infecciones oftalmicas, oticas o nasales.
ECSP109889A (es) Composiciones terapeuticas y usos de las mismas
BR112015018095A2 (pt) moduladores de receptor nmda de espiro-lactama e usos dos mesmos
AR059097A1 (es) Tratamiento a largo plazo de la infeccion por vih
DOP2011000093A (es) Inhibidores de la integrasa del vih