MX2009009463A - Preparacion de una pelicula de rapida disolucion/desintegracion que tiene una alta proporcion de ingrediente activo. - Google Patents

Preparacion de una pelicula de rapida disolucion/desintegracion que tiene una alta proporcion de ingrediente activo.

Info

Publication number
MX2009009463A
MX2009009463A MX2009009463A MX2009009463A MX2009009463A MX 2009009463 A MX2009009463 A MX 2009009463A MX 2009009463 A MX2009009463 A MX 2009009463A MX 2009009463 A MX2009009463 A MX 2009009463A MX 2009009463 A MX2009009463 A MX 2009009463A
Authority
MX
Mexico
Prior art keywords
fast
dissolving
high proportion
active
film preparation
Prior art date
Application number
MX2009009463A
Other languages
English (en)
Inventor
Josh Ghaim
Charlene Ng
Seema Mody
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of MX2009009463A publication Critical patent/MX2009009463A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención proporciona una preparación de película de rápida disolución o rápida desintegración que tiene una alta proporción (es decir, por lo menos aproximadamente 40%) del (los) agente(s) activo(s) y métodos relacionados para su preparación; en una modalidad, el agente activo es un agente farmacéutico y la película comprende entre aproximadamente 10% y aproximadamente 40% de pululano como el polímero soluble en agua primario o el único polímero soluble en agua.
MX2009009463A 2007-03-05 2008-02-26 Preparacion de una pelicula de rapida disolucion/desintegracion que tiene una alta proporcion de ingrediente activo. MX2009009463A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/714,007 US20080220029A1 (en) 2007-03-05 2007-03-05 Fast-dissolving/disintegrating film preparation having high proportion of active
PCT/US2008/002462 WO2008108940A1 (en) 2007-03-05 2008-02-26 Fast-dissolving/disintegrating film preparation having high proportion of active

Publications (1)

Publication Number Publication Date
MX2009009463A true MX2009009463A (es) 2009-09-15

Family

ID=39651356

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009463A MX2009009463A (es) 2007-03-05 2008-02-26 Preparacion de una pelicula de rapida disolucion/desintegracion que tiene una alta proporcion de ingrediente activo.

Country Status (11)

Country Link
US (1) US20080220029A1 (es)
EP (2) EP2444076A1 (es)
KR (1) KR20090128402A (es)
CN (1) CN101626757A (es)
AU (1) AU2008223583B2 (es)
BR (1) BRPI0808475A2 (es)
CA (1) CA2679370A1 (es)
HK (1) HK1139854A1 (es)
MX (1) MX2009009463A (es)
RU (1) RU2492854C2 (es)
WO (1) WO2008108940A1 (es)

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US8623401B2 (en) * 2008-03-27 2014-01-07 Fenwafe Inc. Wafer formulation
ITMI20081450A1 (it) * 2008-08-04 2010-02-05 Biofarmitalia Spa Pellicola solida a rapida dissoluzione nei liquidi
WO2010150930A1 (ko) * 2009-06-25 2010-12-29 (주)벡스코아 불쾌한 맛을 효과적으로 은폐한 경구용 속용 필름
KR20120056824A (ko) * 2009-08-19 2012-06-04 바이엘 파마 악티엔게젤샤프트 소아과 용도를 위한 약물 전달 시스템 （웨이퍼）
TR200907338A1 (tr) * 2009-09-28 2011-04-21 Yedi̇tepe Üni̇versi̇tesi̇ Doğal bileşenler içeren bir film şeridi.
PL2493457T3 (pl) 2009-10-30 2018-01-31 Ix Biopharma Ltd Szybko rozpuszczalna stała postać dawkowana
JP5751868B2 (ja) * 2010-03-30 2015-07-22 日東電工株式会社 フィルム状製剤及びその製造方法
DE102010049706A1 (de) * 2010-10-28 2012-05-03 Hexal Ag Herstellung orodispersibler Filme
JP5875246B2 (ja) * 2010-12-10 2016-03-02 日東電工株式会社 シート状製剤及びシート状製剤の製造方法
JP5555148B2 (ja) * 2010-12-10 2014-07-23 日東電工株式会社 シート状製剤及びシート状製剤の製造方法
US8241661B1 (en) * 2011-06-24 2012-08-14 Fuisz Richard C Biocompatible film with variable cross-sectional properties
KR101303479B1 (ko) * 2011-07-28 2013-09-06 (주)씨엘팜 가식성 필름형성 조성물 및 약물이 함유된 가식성 필름형 제제
JP5841433B2 (ja) 2012-01-11 2016-01-13 日東電工株式会社 口腔内フィルム状基剤及び製剤
WO2013129889A2 (ko) 2012-02-28 2013-09-06 주식회사 서울제약 실데나필을 유효성분으로 함유하며 고미가 은폐된 고함량 속용필름
US9572580B2 (en) 2012-03-16 2017-02-21 Covidien Lp Closure tape dispenser
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RU2525926C1 (ru) * 2013-01-09 2014-08-20 Мария Александровна Никулина Водорастворимая биодеградируемая съедобная упаковочная пленка
RU2015137174A (ru) 2013-03-15 2017-04-24 Смит энд Невью, Инк. Растворимая образующая гель плёнка и способ очистки раны
RS58120B1 (sr) * 2014-07-31 2019-02-28 Pharmathen Sa Kompozicija orodisperzibilnog filma koja sadrži enalapril za lečenje hipertenzije kod pedijatrijske populacije
WO2016071395A1 (en) 2014-11-04 2016-05-12 Acucort Ab Dexamethasone oral film
US9956323B2 (en) 2014-12-18 2018-05-01 Cook Medical Technologies Llc Medical devices for local bioactive delivery
KR101547219B1 (ko) * 2014-12-31 2015-08-25 (주)씨엘팜 다열 다제 구강용해 필름 제조장치 및 제조방법
CN106606779A (zh) * 2015-10-19 2017-05-03 浙江安吉山争医药包装科技有限公司 一种可食性膜片及其制备方法
US11096892B2 (en) * 2017-03-13 2021-08-24 Nano And Advanced Materials Institute Limited High loading and fast disintegration film for fast drug absorption
US11357542B2 (en) 2019-06-21 2022-06-14 Covidien Lp Valve assembly and retainer for surgical access assembly
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Also Published As

Publication number Publication date
RU2009136580A (ru) 2011-04-10
RU2492854C2 (ru) 2013-09-20
EP2444076A1 (en) 2012-04-25
AU2008223583A1 (en) 2008-09-12
CN101626757A (zh) 2010-01-13
EP2131824A1 (en) 2009-12-16
AU2008223583B2 (en) 2013-08-15
BRPI0808475A2 (pt) 2014-07-15
KR20090128402A (ko) 2009-12-15
HK1139854A1 (en) 2010-09-30
EP2131824B1 (en) 2014-09-24
CA2679370A1 (en) 2008-09-12
WO2008108940A1 (en) 2008-09-12
US20080220029A1 (en) 2008-09-11

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