HK1139854A1 - Fast-dissolving disintegrating film preparation having high proportion of active agent - Google Patents

Fast-dissolving disintegrating film preparation having high proportion of active agent

Info

Publication number
HK1139854A1
HK1139854A1 HK10105997.0A HK10105997A HK1139854A1 HK 1139854 A1 HK1139854 A1 HK 1139854A1 HK 10105997 A HK10105997 A HK 10105997A HK 1139854 A1 HK1139854 A1 HK 1139854A1
Authority
HK
Hong Kong
Prior art keywords
dissolving
fast
active agent
high proportion
film preparation
Prior art date
Application number
HK10105997.0A
Other languages
English (en)
Chinese (zh)
Inventor
Charlene Ng
Seema Mody
Josh Ghaim
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of HK1139854A1 publication Critical patent/HK1139854A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK10105997.0A 2007-03-05 2010-06-15 Fast-dissolving disintegrating film preparation having high proportion of active agent HK1139854A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/714,007 US20080220029A1 (en) 2007-03-05 2007-03-05 Fast-dissolving/disintegrating film preparation having high proportion of active
PCT/US2008/002462 WO2008108940A1 (en) 2007-03-05 2008-02-26 Fast-dissolving/disintegrating film preparation having high proportion of active

Publications (1)

Publication Number Publication Date
HK1139854A1 true HK1139854A1 (en) 2010-09-30

Family

ID=39651356

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10105997.0A HK1139854A1 (en) 2007-03-05 2010-06-15 Fast-dissolving disintegrating film preparation having high proportion of active agent

Country Status (11)

Country Link
US (1) US20080220029A1 (es)
EP (2) EP2131824B1 (es)
KR (1) KR20090128402A (es)
CN (1) CN101626757A (es)
AU (1) AU2008223583B2 (es)
BR (1) BRPI0808475A2 (es)
CA (1) CA2679370A1 (es)
HK (1) HK1139854A1 (es)
MX (1) MX2009009463A (es)
RU (1) RU2492854C2 (es)
WO (1) WO2008108940A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8623401B2 (en) * 2008-03-27 2014-01-07 Fenwafe Inc. Wafer formulation
ITMI20081450A1 (it) * 2008-08-04 2010-02-05 Biofarmitalia Spa Pellicola solida a rapida dissoluzione nei liquidi
WO2010150930A1 (ko) * 2009-06-25 2010-12-29 (주)벡스코아 불쾌한 맛을 효과적으로 은폐한 경구용 속용 필름
US20120207836A1 (en) * 2009-08-19 2012-08-16 Bayer Pharma Aktiengesellschaft Drug delivery systems (wafer) for pediatric use
TR200907338A1 (tr) * 2009-09-28 2011-04-21 Yedi̇tepe Üni̇versi̇tesi̇ Doğal bileşenler içeren bir film şeridi.
TR201902233T4 (tr) 2009-10-30 2019-03-21 Ix Biopharma Ltd Hızlı çözünen katı dozaj formu.
JP5751868B2 (ja) * 2010-03-30 2015-07-22 日東電工株式会社 フィルム状製剤及びその製造方法
DE102010049706A1 (de) * 2010-10-28 2012-05-03 Hexal Ag Herstellung orodispersibler Filme
JP5555148B2 (ja) * 2010-12-10 2014-07-23 日東電工株式会社 シート状製剤及びシート状製剤の製造方法
JP5875246B2 (ja) * 2010-12-10 2016-03-02 日東電工株式会社 シート状製剤及びシート状製剤の製造方法
US8241661B1 (en) * 2011-06-24 2012-08-14 Fuisz Richard C Biocompatible film with variable cross-sectional properties
KR101303479B1 (ko) * 2011-07-28 2013-09-06 (주)씨엘팜 가식성 필름형성 조성물 및 약물이 함유된 가식성 필름형 제제
JP5841433B2 (ja) 2012-01-11 2016-01-13 日東電工株式会社 口腔内フィルム状基剤及び製剤
CA2864322C (en) 2012-02-28 2016-08-09 Seoul Pharma. Co., Ltd. High-content fast dissolving film with masking of bitter taste comprising sildenafil as active ingredient
US9572580B2 (en) 2012-03-16 2017-02-21 Covidien Lp Closure tape dispenser
AU2012385956B2 (en) 2012-07-23 2017-03-30 Crayola, Llc Dissolvable films and methods of using the same
CA2890757C (en) 2012-11-14 2021-10-26 Smith & Nephew, Inc. Stable thermolysin hydrogel
RU2525926C1 (ru) * 2013-01-09 2014-08-20 Мария Александровна Никулина Водорастворимая биодеградируемая съедобная упаковочная пленка
AU2014235578B2 (en) 2013-03-15 2017-08-17 Smith & Nephew, Inc. Dissolvable gel-forming film for delivery of active agents
US20170165315A1 (en) * 2014-07-31 2017-06-15 Pharmathen S.A. Orodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population
WO2016071395A1 (en) 2014-11-04 2016-05-12 Acucort Ab Dexamethasone oral film
US9956323B2 (en) 2014-12-18 2018-05-01 Cook Medical Technologies Llc Medical devices for local bioactive delivery
KR101547219B1 (ko) * 2014-12-31 2015-08-25 (주)씨엘팜 다열 다제 구강용해 필름 제조장치 및 제조방법
CN106606779A (zh) * 2015-10-19 2017-05-03 浙江安吉山争医药包装科技有限公司 一种可食性膜片及其制备方法
WO2018166432A1 (en) * 2017-03-13 2018-09-20 Nano And Advanced Materials Institute Limited High loading and fast disintegration film for fast drug absorption
US11357542B2 (en) 2019-06-21 2022-06-14 Covidien Lp Valve assembly and retainer for surgical access assembly
KR102044515B1 (ko) 2019-08-20 2019-11-14 이영환 구강점막 부착력이 우수한 서방형 구강붕해용 필름 및 이의 제조방법
US20210187858A1 (en) * 2019-12-18 2021-06-24 Dieu Cam Vuong Method and system for manufacturing of pharmaceutical formulas in form of orally disintegrating films (odf)
AU2021244054A1 (en) * 2020-03-23 2022-10-13 Aavishkar Oral Strips Private Limited Taste masked and rapidly disintegrating ultra thin iron orodispersible film and a process thereof
EP4185119A1 (en) * 2020-07-23 2023-05-31 Société des Produits Nestlé S.A. Mct formulations for improving cognitive functions and methods of making and using such formulations

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340591A (en) * 1992-01-24 1994-08-23 Fujisawa Pharmaceutical Co., Ltd. Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
DE60020716T2 (de) * 1999-07-22 2005-12-15 Warner-Lambert Co. Llc Filmbildende zusammensetzungen aus pullulan
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
ATE536869T1 (de) * 2001-10-12 2011-12-15 Monosolrx Llc Auf glucan-film basierte wirkstoffverabreichungssysteme
GB0217382D0 (en) * 2002-07-26 2002-09-04 Pfizer Ltd Process for making orally consumable dosage forms
WO2004019885A2 (en) * 2002-08-29 2004-03-11 Linguagen Corp. Fast dissolving film delivery of nucleotides that inhibit the unpleasant taste of bitter tasting medications
ES2365012T3 (es) * 2002-11-12 2011-09-20 Elan Pharma International Limited Formas farmacéuticas sólidas de desintegración rápida que no son friables y que comprenden pululano.
US20070059346A1 (en) * 2003-07-01 2007-03-15 Todd Maibach Film comprising therapeutic agents
US20050170138A1 (en) * 2004-01-20 2005-08-04 Berry Craig J. Laminated thin film with increased dosage loading and improved physical film properties and method for manufacture
US20050186257A1 (en) * 2004-02-20 2005-08-25 Todd Manegold Dissolvable film and method of manufacture
CN100366294C (zh) * 2004-04-30 2008-02-06 量子高科（北京）研究院有限公司 一种口腔速溶制剂及其生产方法
CN101102748A (zh) * 2004-12-23 2008-01-09 麦克内尔-Ppc股份有限公司 具有感觉提示剂的在口中分裂的药物组合物

Also Published As

Publication number Publication date
EP2131824A1 (en) 2009-12-16
CN101626757A (zh) 2010-01-13
RU2492854C2 (ru) 2013-09-20
CA2679370A1 (en) 2008-09-12
KR20090128402A (ko) 2009-12-15
EP2131824B1 (en) 2014-09-24
AU2008223583B2 (en) 2013-08-15
RU2009136580A (ru) 2011-04-10
WO2008108940A1 (en) 2008-09-12
BRPI0808475A2 (pt) 2014-07-15
MX2009009463A (es) 2009-09-15
AU2008223583A1 (en) 2008-09-12
US20080220029A1 (en) 2008-09-11
EP2444076A1 (en) 2012-04-25

Similar Documents

Publication Publication Date Title
HK1139854A1 (en) Fast-dissolving disintegrating film preparation having high proportion of active agent
IL250435A0 (en) Using hil-2-mutein of human origin to prepare a factor for the production of regulatory t cells
HK1219272A1 (zh) 螺羥吲哚化合物及其作為治療劑的用途
EP2251064A4 (en) HYGIENE MASK FOR THE PROTECTION OF OTHERS
HK1211889A1 (en) Therapeutic use of diaminophenothiazines
EP2027849A4 (en) TOPICAL SKIN PREPARATION
IL203051A (en) Use of alpha-ketoglutarate for drug preparation
PT2173345E (pt) Formulação oral de metadoxina
GB2458228B (en) External preparation for skin
IL201465A0 (en) Self-precipitating pharmaceutical formulations for the modified release of active principle
GB0605376D0 (en) Preparation for the relief of disease
IL206577A0 (en) Formulations of flibanserin
IL199771A0 (en) Active substance combination
IL213711A0 (en) Pharmaceuticl formulation of nanonised fenofibrate
ZA200708280B (en) Unit dosage forms of temozolomide
EP2098245A4 (en) USE OF CHOLINESTERASE FOR THE PREPARATION OF ANTI-TACHYKININ MEDICAMENT
IL199756A0 (en) Medically active plaster
PL2219611T3 (pl) Farmaceutyczne postacie do uwalniania związków czynnych
GB2463566B (en) Formulations active against propionibacteria
IL193959A0 (en) Use of caspases for the preparation of medicaments
ZA200806439B (en) Stable dosage formulations of imidazolylalkyl-pyridines
HUE035942T2 (hu) Orvosilag hatásos tapasz
TWM300976U (en) Improved structure of underpants
AU2013257527A1 (en) Unit dosage of apadenoson
GB0802451D0 (en) Sanitary towel with additional protection

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190224