CL2011001834A1 - Antucerpo o fragmento de union del mismo que se enlaza a interleuquina -1 alfa (il-1 alfa) humana; acido nucleico que la codifica; vector; celula huesped; metodo de produccion; composicion farmaceutica que lo comprende; y su uso para preparar un medicamento. - Google Patents

Antucerpo o fragmento de union del mismo que se enlaza a interleuquina -1 alfa (il-1 alfa) humana; acido nucleico que la codifica; vector; celula huesped; metodo de produccion; composicion farmaceutica que lo comprende; y su uso para preparar un medicamento.

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Publication number
CL2011001834A1
CL2011001834A1 CL2011001834A CL2011001834A CL2011001834A1 CL 2011001834 A1 CL2011001834 A1 CL 2011001834A1 CL 2011001834 A CL2011001834 A CL 2011001834A CL 2011001834 A CL2011001834 A CL 2011001834A CL 2011001834 A1 CL2011001834 A1 CL 2011001834A1
Authority
CL
Chile
Prior art keywords
alpha
binds
vector
nucleic acid
pharmaceutical composition
Prior art date
Application number
CL2011001834A
Other languages
English (en)
Inventor
Chungming Wu Chengbin Hsieh
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of CL2011001834A1 publication Critical patent/CL2011001834A1/es

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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Abstract

Proteína de unión que se enlaza a interleuquina-1 alfa (il-1a) humana; ácido nucleico que la codifica; vector; célula huésped; método de producción; composición farmacéutica que la comprende; y su uso para tratar un trastorno en el cual la actividad il-1a es perjudicial.
CL2011001834A 2009-01-29 2011-07-28 Antucerpo o fragmento de union del mismo que se enlaza a interleuquina -1 alfa (il-1 alfa) humana; acido nucleico que la codifica; vector; celula huesped; metodo de produccion; composicion farmaceutica que lo comprende; y su uso para preparar un medicamento. CL2011001834A1 (es)

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EP (1) EP2391652A4 (es)
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AU (1) AU2010208637A1 (es)
BR (1) BRPI1007371A2 (es)
CA (1) CA2749966A1 (es)
CL (1) CL2011001834A1 (es)
CO (1) CO6400231A2 (es)
CR (1) CR20110577A (es)
DO (1) DOP2011000232A (es)
EC (1) ECSP11011239A (es)
IL (1) IL214341A0 (es)
MX (1) MX2011007987A (es)
NZ (1) NZ593905A (es)
PE (1) PE20120586A1 (es)
RU (1) RU2011135768A (es)
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UA (1) UA102722C2 (es)
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KR20110110349A (ko) 2011-10-06
EP2391652A4 (en) 2013-01-02
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WO2010087972A3 (en) 2010-09-16
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RU2011135768A (ru) 2013-03-10
BRPI1007371A2 (pt) 2018-03-27
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