CH681300A5 - - Google Patents
Download PDFInfo
- Publication number
- CH681300A5 CH681300A5 CH1348/90A CH134890A CH681300A5 CH 681300 A5 CH681300 A5 CH 681300A5 CH 1348/90 A CH1348/90 A CH 1348/90A CH 134890 A CH134890 A CH 134890A CH 681300 A5 CH681300 A5 CH 681300A5
- Authority
- CH
- Switzerland
- Prior art keywords
- general formula
- lower alkyl
- compound
- reaction
- carried out
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU193089A HU203333B (en) | 1989-04-21 | 1989-04-21 | Process for producing n-cyano-carboxamidine derivatives |
| HU193189A HU203342B (en) | 1989-04-21 | 1989-04-21 | Process for producing quinazoline deivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH681300A5 true CH681300A5 (nl) | 1993-02-26 |
Family
ID=26317437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1348/90A CH681300A5 (nl) | 1989-04-21 | 1990-04-20 |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPH02292282A (nl) |
| KR (1) | KR900016194A (nl) |
| AT (1) | AT398075B (nl) |
| BG (1) | BG91821A (nl) |
| CA (2) | CA2015066A1 (nl) |
| CH (1) | CH681300A5 (nl) |
| DK (1) | DK99090A (nl) |
| ES (1) | ES2019826A6 (nl) |
| FI (1) | FI902002A0 (nl) |
| GB (1) | GB2231571B (nl) |
| GR (1) | GR900100294A (nl) |
| IT (1) | IT1241128B (nl) |
| PL (1) | PL162976B1 (nl) |
| RU (1) | RU1838309C (nl) |
| SE (1) | SE9001402L (nl) |
| YU (1) | YU70890A (nl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2077252C (en) * | 1992-08-31 | 2001-04-10 | Khashayar Karimian | Methods of making ureas and guanidines, and intermediates therefor |
| ES2096518B1 (es) * | 1994-03-28 | 1997-12-01 | Grupo Farmaceutico Almirall S | Nuevas anilinas. |
| WO2008015525A2 (en) * | 2006-07-31 | 2008-02-07 | Orchid Chemicals & Pharmaceuticals Limited | An improved process for the preparation of alfuzosin hydrochloride |
| EP2152697A2 (en) | 2007-05-04 | 2010-02-17 | Actavis Group PTC EHF | Process for the preparation of alfuzosin and salts thereof |
| AU2008281567B2 (en) | 2007-08-02 | 2012-07-26 | Cipla Limited | Process for the preparation of alfuzosin hydrochloride |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
| US4044135A (en) * | 1975-10-14 | 1977-08-23 | Abbott Laboratories | Antihypertensive agents |
| GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
| US4138561A (en) * | 1977-09-30 | 1979-02-06 | Bristol-Myers Company | Cyanocarboxamidines and quinazoline process |
| FI56836C (fi) * | 1977-10-25 | 1980-04-10 | Fermion Oy | 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner |
| FI57751C (fi) * | 1977-10-25 | 1980-10-10 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner med blodtryckssaenkande verkan |
| FR2421888A1 (fr) * | 1978-02-06 | 1979-11-02 | Synthelabo | Amides d'alkylene-diamines et leur application en therapeutique |
| FI59800C (fi) * | 1979-01-10 | 1981-10-12 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin |
| FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
| ATE32074T1 (de) * | 1983-11-22 | 1988-02-15 | Heumann Ludwig & Co Gmbh | Verfahren zur herstellung von 4-amino-6,7dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)chinazolin und dessen physiologisch annehmbarer salze. |
-
1990
- 1990-04-11 YU YU00708/90A patent/YU70890A/xx unknown
- 1990-04-19 GR GR900100294A patent/GR900100294A/el unknown
- 1990-04-20 RU SU904743794A patent/RU1838309C/ru active
- 1990-04-20 CA CA2015066A patent/CA2015066A1/xx active Pending
- 1990-04-20 DK DK099090A patent/DK99090A/da not_active Application Discontinuation
- 1990-04-20 SE SE9001402A patent/SE9001402L/xx not_active Application Discontinuation
- 1990-04-20 CH CH1348/90A patent/CH681300A5/de not_active IP Right Cessation
- 1990-04-20 CA CA002028953A patent/CA2028953A1/en not_active Abandoned
- 1990-04-20 BG BG091821A patent/BG91821A/bg unknown
- 1990-04-20 PL PL28486090A patent/PL162976B1/pl unknown
- 1990-04-20 JP JP2103239A patent/JPH02292282A/ja active Pending
- 1990-04-20 AT AT0093190A patent/AT398075B/de not_active IP Right Cessation
- 1990-04-20 IT IT20092A patent/IT1241128B/it active IP Right Grant
- 1990-04-20 ES ES9001130A patent/ES2019826A6/es not_active Expired - Lifetime
- 1990-04-20 GB GB9008941A patent/GB2231571B/en not_active Expired - Lifetime
- 1990-04-20 KR KR1019900005608A patent/KR900016194A/ko not_active Application Discontinuation
- 1990-04-20 FI FI902002A patent/FI902002A0/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2015066A1 (en) | 1990-10-21 |
| GR900100294A (el) | 1991-09-27 |
| DK99090D0 (da) | 1990-04-20 |
| ATA93190A (de) | 1994-01-15 |
| PL162976B1 (pl) | 1994-01-31 |
| IT9020092A0 (it) | 1990-04-20 |
| GB2231571B (en) | 1992-09-16 |
| SE9001402D0 (sv) | 1990-04-20 |
| KR900016194A (ko) | 1990-11-12 |
| SE9001402L (sv) | 1990-10-22 |
| FI902002A0 (fi) | 1990-04-20 |
| IT9020092A1 (it) | 1991-10-20 |
| YU70890A (en) | 1992-05-28 |
| RU1838309C (ru) | 1993-08-30 |
| JPH02292282A (ja) | 1990-12-03 |
| PL284860A1 (en) | 1991-03-11 |
| GB2231571A (en) | 1990-11-21 |
| GB9008941D0 (en) | 1990-06-20 |
| BG91821A (bg) | 1993-12-24 |
| DK99090A (da) | 1990-10-22 |
| CA2028953A1 (en) | 1990-10-22 |
| ES2019826A6 (es) | 1991-07-01 |
| AT398075B (de) | 1994-09-26 |
| IT1241128B (it) | 1993-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2096411C1 (ru) | Производные бензимидазолона, смеси их изомеров или их кислотно-аддитивные соли в качестве антагониста рецептора 5-ht*00i*00a и 5-нт*002 | |
| DE69723846T2 (de) | Verfahren zur Herstellung von Sildenafil | |
| Tani et al. | Studies on biologically active halogenated compounds. 1. Synthesis and central nervous system depressant activity of 2-(fluoromethyl)-3-aryl-4 (3H)-quinazolinone derivatives | |
| EP0726899B1 (de) | Neue pyrazincarboxamidderivate, ihre herstellung und ihre verwendung in arzneimitteln | |
| EP0006506B1 (de) | 1,2-Dihydro-chinolin-2-on-Derivate, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel | |
| DE1231705B (de) | Verfahren zur Herstellung von 2, 3-substituierten Chinazolon-(4)-derivaten | |
| DE1620035A1 (de) | 3-Amino-5-X-6-halogenpyrazinonitrile und Verfahren zu deren Herstellung | |
| JPH07188207A (ja) | １−［２ｈ−１−ベンゾピラン−２−オン−８−イル］−ピペラジン誘導体 | |
| DD286581A5 (de) | Verfahren zur herstellung von hetera-aliphatischem carbonsaeureamiden | |
| DE69411589T2 (de) | Indol, indolin und chinolin derivate mit einer 5ht1d antagonistischen wirkung | |
| CH681300A5 (nl) | ||
| DE2508543A1 (de) | Verfahren zur herstellung von imidazo- und pyrimido eckige klammer auf 2,1-b eckige klammer zu -chinazolinen und neue chinazoline | |
| US3200151A (en) | Arylaminoalkyl guanidines | |
| DE2413610A1 (de) | Neue heterocyclische verbindungen und verfahren zu deren herstellung | |
| CS202069B2 (en) | Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines | |
| DE1076691B (de) | Verfahren zur Herstellung von Phenthiazinderivaten | |
| EP0472166A1 (de) | Tricyclische Pyridonderivate | |
| EP0552758A1 (de) | N-5-geschützte 2,5-Diamino-4,6-dichlorpyrimidine und Verfahren zu deren Herstellung | |
| DE2903850A1 (de) | 2-amino-8-cyclopropyl-5-oxo-5,8- dihydro-pyrido eckige klammer auf 2,3-d eckige klammer zu -pyrimidin-6-carnonsaeuren, verfahren zu ihrer herstellung sowie ihrer verwendung als antibakterielle mittel | |
| KR880001298B1 (ko) | 벤조일-페닐-피페리딘 유도체의 제법 | |
| DE69230730T2 (de) | VERFAHREN ZUR HERSTELLUNG VON BENZO[b]NAPHTHYRIDINEN | |
| DD297971A5 (de) | Verfahren zur herstellung von chinazolinderivaten | |
| SU999967A3 (ru) | Способ получени 6-N-замещенных 6-амино-3-пиридазинилгидразинов или их солей | |
| AU689478B2 (en) | Pharmacologically active enantiomers of triazolone compounds | |
| NO129744B (nl) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |