CH644603A5 - Aurone derivatives and process for their preparation - Google Patents

Aurone derivatives and process for their preparation Download PDF

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Publication number
CH644603A5
CH644603A5 CH820379A CH820379A CH644603A5 CH 644603 A5 CH644603 A5 CH 644603A5 CH 820379 A CH820379 A CH 820379A CH 820379 A CH820379 A CH 820379A CH 644603 A5 CH644603 A5 CH 644603A5
Authority
CH
Switzerland
Prior art keywords
group
carbon atoms
carboxy
formula
compound according
Prior art date
Application number
CH820379A
Other languages
English (en)
French (fr)
Inventor
Stephen Richard Baker
William James Ross
William Boffey Jamieson
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of CH644603A5 publication Critical patent/CH644603A5/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
CH820379A 1978-09-13 1979-09-11 Aurone derivatives and process for their preparation CH644603A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7836705 1978-09-13

Publications (1)

Publication Number Publication Date
CH644603A5 true CH644603A5 (en) 1984-08-15

Family

ID=10499649

Family Applications (1)

Application Number Title Priority Date Filing Date
CH820379A CH644603A5 (en) 1978-09-13 1979-09-11 Aurone derivatives and process for their preparation

Country Status (29)

Country Link
US (1) USRE32196E (es)
JP (1) JPS5540692A (es)
KR (1) KR830001919B1 (es)
AR (2) AR228020A1 (es)
AT (1) AT376968B (es)
AU (1) AU535369B2 (es)
BG (2) BG43187A3 (es)
CA (1) CA1202309A (es)
CH (1) CH644603A5 (es)
CS (1) CS214806B2 (es)
DD (1) DD146046A5 (es)
DK (1) DK382579A (es)
EG (1) EG14105A (es)
ES (1) ES484115A1 (es)
FI (1) FI792850A (es)
GR (1) GR71200B (es)
HU (1) HU181450B (es)
IE (1) IE48824B1 (es)
IL (1) IL58229A (es)
IT (1) IT1162395B (es)
MX (1) MX6232E (es)
NZ (1) NZ191556A (es)
PH (1) PH15712A (es)
PL (1) PL124296B1 (es)
PT (1) PT70170A (es)
SE (1) SE447382B (es)
SU (1) SU1138027A3 (es)
YU (1) YU222079A (es)
ZA (1) ZA794836B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055128A1 (de) * 2000-01-28 2001-08-02 Merck Patent Gmbh Benzofuranonderivate enthaltende formulierung zum schutz vor oxidativem stress

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307070B1 (en) 1996-01-26 2001-10-23 Phytera, Inc. Substituted aurone derivatives
AU1709897A (en) * 1996-01-26 1997-08-20 Phytera, Inc. Antimicrobial aurone derivatives
AU751213B2 (en) * 1997-07-25 2002-08-08 Phytera, Inc. Substituted aurone derivatives
JP4166433B2 (ja) * 1997-09-11 2008-10-15 第一製薬株式会社 ホルモン依存性疾患治療剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT277985B (de) * 1967-11-14 1970-01-12 Schering Ag Verfahren zur Herstellung von neuen Nitro-furan-, -thiophen- oder -pyrrol-derivaten
US4115567A (en) * 1973-12-27 1978-09-19 Carlo Erba S. P. A. 6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof
US3975380A (en) * 1974-06-03 1976-08-17 Smithkline Corporation Substituted aurones
US4067993A (en) * 1975-09-24 1978-01-10 Riker Laboratories, Inc. Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids
US4143145A (en) * 1977-01-12 1979-03-06 Carlo Erba S. P. A. Substituted 2-vinyl-chromones and process for their preparation
FR2396756A1 (fr) * 1977-07-06 1979-02-02 Inst Nat Sante Rech Med Nouvelles benzylidene-2-benzofurannones-3, leur obtention et leur application a titre de medicaments
IT1093805B (it) * 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
US4143055A (en) * 1978-03-27 1979-03-06 Gruppo Lepetit S.P.A. 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055128A1 (de) * 2000-01-28 2001-08-02 Merck Patent Gmbh Benzofuranonderivate enthaltende formulierung zum schutz vor oxidativem stress
US6903134B2 (en) 2000-01-28 2005-06-07 Merck Patent Gmbh Formulation comprising benzofuranone derivatives for protection against oxidative stress

Also Published As

Publication number Publication date
PH15712A (en) 1983-03-14
FI792850A (fi) 1980-03-14
PL218277A1 (es) 1980-07-14
IL58229A (en) 1984-05-31
IL58229A0 (en) 1979-12-30
IT7950245A0 (it) 1979-09-12
SE447382B (sv) 1986-11-10
USRE32196E (en) 1986-07-01
BG43187A3 (en) 1988-04-15
NZ191556A (en) 1981-03-16
AR228020A1 (es) 1983-01-14
DK382579A (da) 1980-03-14
JPS5540692A (en) 1980-03-22
KR830001919B1 (ko) 1983-09-23
AU535369B2 (en) 1984-03-15
IT1162395B (it) 1987-03-25
BG40315A3 (en) 1986-11-14
HU181450B (en) 1983-07-28
CA1202309A (en) 1986-03-25
MX6232E (es) 1985-01-14
ZA794836B (en) 1981-03-25
CS214806B2 (en) 1982-06-25
PL124296B1 (en) 1983-01-31
ATA598079A (de) 1984-06-15
YU222079A (en) 1983-02-28
AU5078079A (en) 1980-03-20
GR71200B (es) 1983-04-11
DD146046A5 (de) 1981-01-21
EG14105A (en) 1983-03-31
PT70170A (en) 1979-10-01
AT376968B (de) 1985-01-25
AR226210A1 (es) 1982-06-15
SE7907532L (sv) 1980-03-14
IE48824B1 (en) 1985-05-29
SU1138027A3 (ru) 1985-01-30
IE791729L (en) 1980-03-13
ES484115A1 (es) 1980-04-16

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