CH641805A5 - Derivatives of 3-thio-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo-[3.2.0]hept-2-ene-2-carbo xylic acid, process for their preparation and medicaments containing these compounds - Google Patents

Derivatives of 3-thio-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo-[3.2.0]hept-2-ene-2-carbo xylic acid, process for their preparation and medicaments containing these compounds Download PDF

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Publication number
CH641805A5
CH641805A5 CH233978A CH233978A CH641805A5 CH 641805 A5 CH641805 A5 CH 641805A5 CH 233978 A CH233978 A CH 233978A CH 233978 A CH233978 A CH 233978A CH 641805 A5 CH641805 A5 CH 641805A5
Authority
CH
Switzerland
Prior art keywords
compound
formula
salt
salts
fractions
Prior art date
Application number
CH233978A
Other languages
German (de)
English (en)
Inventor
Stephen John Box
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9366/77A external-priority patent/GB1601688A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of CH641805A5 publication Critical patent/CH641805A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
CH233978A 1977-03-05 1978-03-03 Derivatives of 3-thio-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo-[3.2.0]hept-2-ene-2-carbo xylic acid, process for their preparation and medicaments containing these compounds CH641805A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9366/77A GB1601688A (en) 1977-03-05 1977-03-05 6-(1-hydroxyethyl)-7-oxo 1-aza bicyclo (3,2,0)-hept-2-ene-2-carboxylic acid derivatives and their use in pharmaceutical compositions
GB3283677 1977-08-05

Publications (1)

Publication Number Publication Date
CH641805A5 true CH641805A5 (en) 1984-03-15

Family

ID=26242889

Family Applications (1)

Application Number Title Priority Date Filing Date
CH233978A CH641805A5 (en) 1977-03-05 1978-03-03 Derivatives of 3-thio-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo-[3.2.0]hept-2-ene-2-carbo xylic acid, process for their preparation and medicaments containing these compounds

Country Status (11)

Country Link
JP (1) JPS53116396A (fr)
AU (1) AU525142B2 (fr)
CH (1) CH641805A5 (fr)
DE (1) DE2808563A1 (fr)
DK (1) DK98478A (fr)
ES (1) ES467562A1 (fr)
FR (1) FR2401162A1 (fr)
IE (1) IE46736B1 (fr)
IT (1) IT7848280A0 (fr)
NL (1) NL7802356A (fr)
SE (1) SE7802462L (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
EP0008885B1 (fr) * 1978-09-09 1983-11-30 Beecham Group Plc Composés de bêta-lactame, leur préparation et application
EP0033209B1 (fr) * 1980-01-25 1984-06-13 Beecham Group Plc Composés dérivés de bêta-lactame, leur préparation et leur utilisation
IN155384B (fr) * 1980-05-14 1985-01-19 Pfizer
JP4977670B2 (ja) * 2008-09-11 2012-07-18 啓司 関口 生花整形器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143713C (da) * 1975-11-21 1982-03-08 Merck & Co Inc Fremgangsmaade til fremstilling af et antibiotisk stof n-acetyl-thienamycin og salte deraf
DK143712C (da) * 1975-11-21 1982-03-22 Merck & Co Inc Fremgangsmaade til fremstilling af de antibiotiske stoffer 890a1 og 890a3
DK145504C (da) * 1976-04-28 1983-04-25 Merck & Co Inc Fremgangsmaade til fremstilling af det antibiotiske stof 890a2og/eller det antibiotiske stof 890a5 og farmaceutisk acceptable salte deraf

Also Published As

Publication number Publication date
FR2401162A1 (fr) 1979-03-23
FR2401162B1 (fr) 1980-08-29
AU3384178A (en) 1979-09-06
IT7848280A0 (it) 1978-03-03
IE46736B1 (en) 1983-09-07
SE7802462L (sv) 1978-09-06
DE2808563A1 (de) 1978-09-07
IE780443L (en) 1978-09-05
NL7802356A (nl) 1978-09-07
ES467562A1 (es) 1980-05-16
DK98478A (da) 1978-09-06
AU525142B2 (en) 1982-10-21
JPS53116396A (en) 1978-10-11

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