CH634840A5 - 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate. - Google Patents

2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate. Download PDF

Info

Publication number
CH634840A5
CH634840A5 CH710378A CH710378A CH634840A5 CH 634840 A5 CH634840 A5 CH 634840A5 CH 710378 A CH710378 A CH 710378A CH 710378 A CH710378 A CH 710378A CH 634840 A5 CH634840 A5 CH 634840A5
Authority
CH
Switzerland
Prior art keywords
compound
formula
salt
benzo
salts
Prior art date
Application number
CH710378A
Other languages
German (de)
English (en)
Inventor
Raymond Dr Bernasconi
Pier Giorgio Dr Ferrini
Richard Dr Goeschke
Jacques Dr Gosteli
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to PT66412A priority Critical patent/PT66412B/pt
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH710378A priority patent/CH634840A5/de
Priority to PL21637879A priority patent/PL216378A3/xx
Priority to PL21637679A priority patent/PL216376A3/xx
Priority to PL21637779A priority patent/PL216377A3/xx
Priority to DE19792924496 priority patent/DE2924496A1/de
Priority to GB7921851A priority patent/GB2024220B/en
Priority to CY1288A priority patent/CY1288A/xx
Priority to FI792011A priority patent/FI792011A/fi
Priority to ES481936A priority patent/ES481936A2/es
Priority to FR7916603A priority patent/FR2429792A2/fr
Priority to DD79213935A priority patent/DD144544A6/de
Priority to SE7905631A priority patent/SE445737B/sv
Priority to GR59451A priority patent/GR82335B/el
Priority to IT49562/79A priority patent/IT1164125B/it
Priority to CA330,705A priority patent/CA1125761A/en
Priority to AT0451779A priority patent/AT373598B/de
Priority to HU79CI1943A priority patent/HU181663B/hu
Priority to NZ190868A priority patent/NZ190868A/xx
Priority to AT0451679A priority patent/AT373597B/de
Priority to AU48509/79A priority patent/AU531535B2/en
Priority to NO792178A priority patent/NO151323C/no
Priority to BE0/196017A priority patent/BE877339R/xx
Priority to ZA793230A priority patent/ZA793230B/xx
Priority to DK274279A priority patent/DK152047C/da
Priority to AT0451579A priority patent/AT374199B/de
Priority to IL5768479A priority patent/IL57684A/xx
Priority to AR277124A priority patent/AR231540A1/es
Priority to JP8154679A priority patent/JPS559075A/ja
Priority to NL7905084A priority patent/NL7905084A/nl
Priority to IE1205/79A priority patent/IE48767B1/en
Priority to US06/204,747 priority patent/US4396621A/en
Publication of CH634840A5 publication Critical patent/CH634840A5/de
Priority to AT171483A priority patent/AT392787B/de
Priority to SG159/85A priority patent/SG15985G/en
Priority to HK425/85A priority patent/HK42585A/xx
Priority to MY212/85A priority patent/MY8500212A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH710378A 1976-04-09 1978-06-29 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate. CH634840A5 (de)

Priority Applications (36)

Application Number Priority Date Filing Date Title
PT66412A PT66412B (en) 1976-04-09 1977-04-07 Process for the manufacture of new oxothia compounds
CH710378A CH634840A5 (de) 1978-06-29 1978-06-29 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate.
PL21637879A PL216378A3 (hu) 1978-06-29 1979-06-16
PL21637679A PL216376A3 (hu) 1978-06-29 1979-06-16
PL21637779A PL216377A3 (hu) 1978-06-29 1979-06-16
DE19792924496 DE2924496A1 (de) 1978-06-29 1979-06-18 Neue oxathiaverbindungen, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische praeparate und ihre verwendung als arzneimittelwirkstoff
CY1288A CY1288A (en) 1978-06-29 1979-06-22 Oxothia compounds processes for their preparation pharmaceutical preparations containing these compounds and their use as a medicinal active compound
GB7921851A GB2024220B (en) 1978-06-29 1979-06-22 Oxothia compounds processes for their preparation pharmaceutical preparations containing these compounds and their uas a medicinal active compound
FI792011A FI792011A (fi) 1978-06-29 1979-06-25 Foerfarande foer framstaellning av nya oxatiafoereningar
ES481936A ES481936A2 (es) 1978-06-29 1979-06-26 Mejoras introducidas en la patente principal: procedimiento para la obtencion de compuestos oxotio.
FR7916603A FR2429792A2 (fr) 1978-06-29 1979-06-27 Nouveaux composes oxothia, leur preparation et leur application en tant que substances actives medicamenteuses
DD79213935A DD144544A6 (de) 1978-06-29 1979-06-27 Verfahren zur herstellung neuer oxathiaverbindungen
SE7905631A SE445737B (sv) 1978-06-29 1979-06-27 Forfarande for framstellning av n-(2-tienyl)-2-oxo-2,3-dihydro-benso/b/tiofen-3-karboxamid
GR59451A GR82335B (hu) 1978-06-29 1979-06-27
IT49562/79A IT1164125B (it) 1978-06-29 1979-06-27 Ossotiacomposti e procedimento per la loro produzione ed impiego in preparati farmaceutici
CA330,705A CA1125761A (en) 1978-06-29 1979-06-27 Process for the manufacture of novel oxothia compounds
HU79CI1943A HU181663B (en) 1978-06-29 1979-06-28 Process for preparing n-/2-thienyl/-2-oxo-2,3-dihydro-benzo/b/-thiophene-3-carboxamide and salts thereof
AT0451779A AT373598B (de) 1978-06-29 1979-06-28 Verfahren zur herstellung einer neuen oxathiaverbindung und ihrer salze
NZ190868A NZ190868A (en) 1977-03-31 1979-06-28 N-heterocyclyl-2-oxo-2 3-dihydro-benzo(b) thiophen-3-carboxamides pharmaceutical compositions
AT0451679A AT373597B (de) 1978-06-29 1979-06-28 Verfahren zur herstellung einer neuen oxathiaverbindung und ihrer salze
AU48509/79A AU531535B2 (en) 1978-06-29 1979-06-28 Oxothia compounds
NO792178A NO151323C (no) 1978-06-29 1979-06-28 Analogifremgangsmaate til fremstilling av et terapeutisk aktivt n-(2-tienyl)-2-okso-2,3-dihydro-benzo(b)tiofen-3-karboksamid
BE0/196017A BE877339R (fr) 1978-06-29 1979-06-28 Nouveaux composes oxathia, leur preparation et leur application en tant que medicaments
ZA793230A ZA793230B (en) 1978-06-29 1979-06-28 Novel oxothia compounds,processes for their preparation,pharmaceutical preparations containing these compounds and their use as a medicinal active compound
DK274279A DK152047C (da) 1978-06-29 1979-06-28 Analogifremgangsmaade til fremstilling af n-(2-thienyl)-2-oxo-2,3-dihydro-benzo(b)thiophen-3-carboxamid eller salte deraf med baser
AT0451579A AT374199B (de) 1978-06-29 1979-06-28 Verfahren zur herstellung einer neuen oxathiaverbindung und ihrer salze
IL5768479A IL57684A (en) 1977-04-08 1979-06-28 2,3-dihydro-2-oxo-benzo(b)thiophen-2-carboxamide,its manufacture and pharmaceutical compositions containing it
AR277124A AR231540A1 (es) 1978-06-29 1979-06-29 Procedimiento para la elaboracion de derivados de 2-oxo-3-n-2,3-dihidro b-tiofeno y sus sales
JP8154679A JPS559075A (en) 1978-06-29 1979-06-29 Novel oxothia compound*its manufacture*drug composition containing it and use as medical material
NL7905084A NL7905084A (nl) 1978-06-29 1979-06-29 Oxothiaverbindingen, werkwijzen voor de bereiding daar- van, farmaceutische preparaten die de verbindingen bevatten en de toepassing daarvan in farmaceutische preparaten als werkzame verbinding.
IE1205/79A IE48767B1 (en) 1978-06-29 1979-08-08 Novel oxothia compounds,processes for their preparation,pharmaceutical preparations containing these compounds and such compounds for therapeutic use
US06/204,747 US4396621A (en) 1976-04-09 1980-11-07 Certain 2-oxo-2,3-dihydro-3-benzothiophene-carboxamides and their pharmaceutical compositions
AT171483A AT392787B (de) 1978-06-29 1983-05-10 Verfahren zur herstellung des neuen n-(2-thienyl)-2-oxo-2,3-dihydro-benzo(b)thiophen-3-carboxamids
SG159/85A SG15985G (en) 1978-06-29 1985-03-01 Novel oxothia compounds,processes for their preparation,pharmaceutical preparations containing these compounds and such compounds for therapeutic use
HK425/85A HK42585A (en) 1978-06-29 1985-05-30 Novel oxothia compounds,processes for their preparation,pharmaceutical preparations containing these compounds and such compounds for therapeutic use
MY212/85A MY8500212A (en) 1978-06-29 1985-12-30 Novel oxothia compounds processes for their preparation,pharmaceutical preparations containing these compounds and their use as a medicinal active compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH710378A CH634840A5 (de) 1978-06-29 1978-06-29 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate.

Publications (1)

Publication Number Publication Date
CH634840A5 true CH634840A5 (de) 1983-02-28

Family

ID=4320005

Family Applications (1)

Application Number Title Priority Date Filing Date
CH710378A CH634840A5 (de) 1976-04-09 1978-06-29 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate.

Country Status (26)

Country Link
JP (1) JPS559075A (hu)
AR (1) AR231540A1 (hu)
AT (3) AT373597B (hu)
AU (1) AU531535B2 (hu)
BE (1) BE877339R (hu)
CA (1) CA1125761A (hu)
CH (1) CH634840A5 (hu)
CY (1) CY1288A (hu)
DD (1) DD144544A6 (hu)
DE (1) DE2924496A1 (hu)
DK (1) DK152047C (hu)
ES (1) ES481936A2 (hu)
FI (1) FI792011A (hu)
FR (1) FR2429792A2 (hu)
GB (1) GB2024220B (hu)
GR (1) GR82335B (hu)
HK (1) HK42585A (hu)
HU (1) HU181663B (hu)
IE (1) IE48767B1 (hu)
MY (1) MY8500212A (hu)
NL (1) NL7905084A (hu)
NO (1) NO151323C (hu)
PL (3) PL216376A3 (hu)
SE (1) SE445737B (hu)
SG (1) SG15985G (hu)
ZA (1) ZA793230B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800211A (en) * 1986-08-18 1989-01-24 Merck & Co., Inc. 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
JP2004501910A (ja) 2000-06-28 2004-01-22 イーライ・リリー・アンド・カンパニー 新規なｓＰＬＡ２インヒビター

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2713584C2 (de) * 1976-04-09 1986-09-04 Ciba-Geigy Ag, Basel Benzo[b]thiophencarboxamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
JPS6218556A (ja) * 1985-07-18 1987-01-27 Fuji Photo Film Co Ltd ハロゲン化銀カラ−写真感光材料

Also Published As

Publication number Publication date
DD144544A6 (de) 1980-10-22
ATA451579A (de) 1983-08-15
FR2429792B2 (hu) 1983-02-04
JPH0215549B2 (hu) 1990-04-12
ZA793230B (en) 1980-06-25
ATA451779A (de) 1983-06-15
ES481936A2 (es) 1980-06-16
SE7905631L (sv) 1979-12-30
CY1288A (en) 1985-07-05
GB2024220B (en) 1982-12-01
AT373598B (de) 1984-02-10
DK152047B (da) 1988-01-25
AU531535B2 (en) 1983-08-25
FR2429792A2 (fr) 1980-01-25
GB2024220A (en) 1980-01-09
AT374199B (de) 1984-03-26
PL216377A3 (hu) 1980-03-24
PL216376A3 (hu) 1980-03-24
AT373597B (de) 1984-02-10
HK42585A (en) 1985-06-07
PL216378A3 (hu) 1980-03-24
JPS559075A (en) 1980-01-22
AU4850979A (en) 1980-02-07
DE2924496A1 (de) 1980-01-17
NO151323C (no) 1985-03-20
NO792178L (no) 1980-01-03
MY8500212A (en) 1985-12-31
IE791205L (en) 1979-12-29
BE877339R (fr) 1979-12-28
AR231540A1 (es) 1984-12-28
NO151323B (no) 1984-12-10
CA1125761A (en) 1982-06-15
FI792011A (fi) 1979-12-30
DK152047C (da) 1988-08-08
HU181663B (en) 1983-10-28
NL7905084A (nl) 1980-01-03
IE48767B1 (en) 1985-05-15
SE445737B (sv) 1986-07-14
GR82335B (hu) 1984-12-13
ATA451679A (de) 1983-06-15
SG15985G (en) 1985-08-16
DK274279A (da) 1979-12-30
DE2924496C2 (hu) 1989-12-21

Similar Documents

Publication Publication Date Title
DE3131752C2 (hu)
AT372955B (de) Verfahren zur herstellung neuer benzopyranderivate
CH634840A5 (de) 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate.
EP0008072B1 (de) Substituierte Anthranilsäureamide, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Herstellung
DE2713584C2 (de) Benzo[b]thiophencarboxamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE2612926A1 (de) Neue acyl-derivate der 6-(alpha- amino-phenylacetamido)-penicillansaeure
US4260779A (en) Oxothia compounds
AT392787B (de) Verfahren zur herstellung des neuen n-(2-thienyl)-2-oxo-2,3-dihydro-benzo(b)thiophen-3-carboxamids
US4396621A (en) Certain 2-oxo-2,3-dihydro-3-benzothiophene-carboxamides and their pharmaceutical compositions
CH638204A5 (en) Process for preparing oxothia compounds
EP0000574B1 (de) Benzimidazol-2-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneimitteln
CH629797A5 (en) Process for the preparation of salts of oxothia compounds
AT357149B (de) Verfahren zur herstellung neuer 2,3-dihydro -2-oxo-thiophenderivate
EP0125484A1 (de) Polycyclische Carbonsäureverbindungen, Verfahren zu ihrer Herstellung und Präparate enthaltend solche Carbonsäureverbindungen, sowie deren Verwendung
AT357150B (de) Verfahren zur herstellung neuer 2,3-dihydro-2 -oxo-thiophenderivate
AT375350B (de) Verfahren zur herstellung neuer substituierter heterocyclylverbindungen und ihrer salze
AT358028B (de) Verfahren zur herstellung neuer 2,3-dihydro- -2-oxothiophenderivate und ihrer salze
DE2520107A1 (de) Verfahren zur herstellung von neuen aminoacyl-verbindungen
EP0280268A1 (de) Thienothiopyrane
EP0005141A1 (de) Benzothiopyranderivate, ihre Herstellung und diese enthaltende pharmazeutische Präparate
EP0124479A1 (de) Iminosulfonamide und Verfahren zu ihrer Herstellung, die pharmazeutische Präparate solche Verbindungen enthalten, sowie die Verbindungen zur Verwendung
DE2804798A1 (de) Verfahren zur herstellung neuer indolylglyoxylsaeurederivate
DE3036553A1 (de) Substituierte 2-(pyridyl-cyclopropyl)chromone, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
EP0406614A1 (de) Neue Sulfamoyl-Thiophene, ein Verfahren zu ihrer Herstellung und ihre Verwendung
CH640848A5 (en) Benzopyran derivatives

Legal Events

Date Code Title Description
PL Patent ceased