CH627281A5 - - Google Patents

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Publication number
CH627281A5
CH627281A5 CH645975A CH645975A CH627281A5 CH 627281 A5 CH627281 A5 CH 627281A5 CH 645975 A CH645975 A CH 645975A CH 645975 A CH645975 A CH 645975A CH 627281 A5 CH627281 A5 CH 627281A5
Authority
CH
Switzerland
Prior art keywords
complex
sample
mixture
complexes
amount
Prior art date
Application number
CH645975A
Other languages
German (de)
English (en)
Inventor
Pierre Lucien Masson
Joseph Felix Heremans
Original Assignee
Technicon Instr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technicon Instr filed Critical Technicon Instr
Publication of CH627281A5 publication Critical patent/CH627281A5/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/966—Chemistry: molecular biology and microbiology involving an enzyme system with high turnover rate or complement magnified assay, e.g. multi-enzyme systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CH645975A 1974-05-20 1975-05-20 CH627281A5 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB22377/74A GB1508132A (en) 1974-05-20 1974-05-20 Analysis of biological fluids

Publications (1)

Publication Number Publication Date
CH627281A5 true CH627281A5 (it) 1981-12-31

Family

ID=10178404

Family Applications (4)

Application Number Title Priority Date Filing Date
CH645975A CH627281A5 (it) 1974-05-20 1975-05-20
CH645875A CH631015A5 (de) 1974-05-20 1975-05-20 Verfahren zur herstellung eines reagenzes zum nachweis oder zur bestimmung von antikoerpern, antigenen und antikoerper/antigen-komplexen in einer fluessigkeit.
CH878779A CH637770A5 (de) 1974-05-20 1979-09-28 Zur durchfuehrung von immunoassays sowie zur abtrennung eines antikoerper/antigen-komplexes aus einer fluessigkeitsprobe geeignetes reagenz sowie verwendung dieses reagenzes.
CH918880A CH630465A5 (de) 1974-05-20 1980-12-12 Verfahren zum nachweis oder zur bestimmung eines antikoerper/antigen-komplexes in einer fluidprobe.

Family Applications After (3)

Application Number Title Priority Date Filing Date
CH645875A CH631015A5 (de) 1974-05-20 1975-05-20 Verfahren zur herstellung eines reagenzes zum nachweis oder zur bestimmung von antikoerpern, antigenen und antikoerper/antigen-komplexen in einer fluessigkeit.
CH878779A CH637770A5 (de) 1974-05-20 1979-09-28 Zur durchfuehrung von immunoassays sowie zur abtrennung eines antikoerper/antigen-komplexes aus einer fluessigkeitsprobe geeignetes reagenz sowie verwendung dieses reagenzes.
CH918880A CH630465A5 (de) 1974-05-20 1980-12-12 Verfahren zum nachweis oder zur bestimmung eines antikoerper/antigen-komplexes in einer fluidprobe.

Country Status (11)

Country Link
US (2) US4062935A (it)
JP (4) JPS5949545B2 (it)
AU (2) AU498364B2 (it)
BE (2) BE829278A (it)
CH (4) CH627281A5 (it)
DE (3) DE2522087C2 (it)
FR (2) FR2272398B1 (it)
GB (1) GB1508132A (it)
IT (1) IT1038305B (it)
NL (2) NL182175C (it)
SE (4) SE435425B (it)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
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GB1508132A (en) * 1974-05-20 1978-04-19 Technicon Instr Analysis of biological fluids
US4283383A (en) * 1974-05-20 1981-08-11 Technicon Instruments Corporation Analysis of biological fluids
SE441041B (sv) * 1976-09-08 1985-09-02 Pharmacia Diagnostics Ab Sett vid pavisning av rheumatoida faktorer
SE441042B (sv) * 1976-09-08 1985-09-02 Pharmacia Diagnostics Ab Sett att pavisa rheumatoida faktorer
JPS5339265U (it) * 1976-09-09 1978-04-05
GB1603406A (en) * 1977-08-31 1981-11-25 Nat Res Dev Assay of immune complexes
GB1590524A (en) * 1976-11-24 1981-06-03 Nat Res Dev Assay of immune complexes
GB1592450A (en) * 1976-12-10 1981-07-08 Technicon Instr Biological analysis
JPS5387877U (it) * 1976-12-21 1978-07-19
JPS5387876U (it) * 1976-12-21 1978-07-19
JPS53115946A (en) * 1977-03-18 1978-10-09 Matsushita Electric Ind Co Ltd High frequency heating apparatus
JPS53119441A (en) * 1977-03-28 1978-10-18 Matsushita Electric Ind Co Ltd High-frequency heater
JPS53128781A (en) * 1977-04-15 1978-11-10 Matsushita Electric Ind Co Ltd Touch switch and method of producing same
DE2731992A1 (de) * 1977-07-15 1979-02-01 Behringwerke Ag Verfahren zur bestimmung von immunologisch veraendertem immunglobulin
ES471585A1 (es) * 1977-07-15 1979-01-16 Behringwerke Ag Procedimiento para la determinacion de reactivos fc
JPS5423977A (en) * 1977-07-22 1979-02-22 Sato Shinichi Contacttswitch circuit
US4210622A (en) * 1977-09-07 1980-07-01 National Research Development Corporation Kit for assay of immune complexes
US4231750A (en) * 1977-12-13 1980-11-04 Diagnostic Reagents, Inc. Methods for performing chemical assays using fluorescence and photon counting
JPS54113064U (it) * 1978-01-30 1979-08-08
DE2836046A1 (de) * 1978-08-17 1980-02-28 Behringwerke Ag Immunologisches bestimmungsverfahren
US4307190A (en) * 1978-10-30 1981-12-22 Technicon Instruments Corporation Immunoassay using ascitic fluid
DE2853453A1 (de) * 1978-12-11 1980-06-19 Behringwerke Ag Mittel zur therapie von immunkomplexerkrankungen
FI58566C (fi) * 1979-02-22 1981-02-10 Orion Yhtymae Oy Foerbaettrat foerfarande att framstaella indikatorsystem foer bestaemning av antigen-antikroppsreaktioner med hjaelp av hemolys i gel
GB2045431B (en) * 1979-02-26 1983-04-20 Technicon Instr Immunoassay utilising two particulate reagents
US4282002A (en) * 1979-09-06 1981-08-04 Akzona Incorporated Sensitized sheep stroma immunoassay for rheumatoid factor
US4399229A (en) * 1980-04-14 1983-08-16 Immutron, Inc. Rapid radioimmunoassay product and method of making and using same
JPS5742854A (en) * 1980-08-27 1982-03-10 Seikagaku Kogyo Co Ltd Latex sensitized with complement 1q
GB2109932B (en) * 1980-10-24 1984-08-01 David Parratt A method of diagnosis
US4427781A (en) * 1981-03-16 1984-01-24 International Institute Of Cellular And Molecular Pathology Particle agglutination immunoassay with agglutinator for determining haptens; PACIA
EP0089367A1 (en) * 1981-09-18 1983-09-28 Georgetown University Monoclonal antibody detection system
US4434227A (en) 1982-02-08 1984-02-28 Abbott Laboratories Immunoassay for class specific immunoglobulin antibodies
JPS59501123A (ja) * 1982-03-31 1984-06-28 バイオスタ−・メディカル・プロダクツ・インコ−ポレ−テッド 免疫分析法、それに使用する装置及びかかる装置の製法
US4450231A (en) * 1982-03-31 1984-05-22 Biostar Medical Products, Inc. Immunoassay for determination of immune complexes with polymer-coated plastic base
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US4427779A (en) 1982-05-26 1984-01-24 Ortho Diagnostic Systems Inc. Agglutination-inhibition test method for detecting immune complexes
US4420461A (en) * 1982-05-26 1983-12-13 Ortho Diagnostic Systems Inc. Agglutination-inhibition test kit for detecting immune complexes
US4459361A (en) * 1982-06-04 1984-07-10 Angenics, Inc. Ligand assay with one or two particulate reagents and filter
US4547466A (en) * 1983-06-01 1985-10-15 Allied Corporation Detecting rheumatoid factor with synthetic particles having immune complexes thereon
US4551435A (en) * 1983-08-24 1985-11-05 Immunicon, Inc. Selective removal of immunospecifically recognizable substances from solution
US4595654A (en) * 1983-11-07 1986-06-17 Immunomedics Inc. Method for detecting immune complexes in serum
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
EP0177023A3 (en) * 1984-10-02 1987-08-12 The Calpis Food Industry Co., Ltd. Substance-conjugated complement component c1q
JPS6178041U (it) * 1984-10-29 1986-05-24
FR2585367B1 (fr) * 1985-07-26 1987-10-02 Lyonnaise Eaux Procede de dosage immunologique en continu de composes organiques dans un fluide en circulation, et dispositif de mise en oeuvre
DE3603085C1 (en) * 1986-02-01 1987-04-23 Medac Klinische Spezialpraep Immunological method for detecting antigen-specific antibodies and test kit for carrying out the method
US5223441A (en) 1986-10-09 1993-06-29 Syntex (U.S.A.) Inc. Receptors for immune complexes
DE3839869C2 (de) * 1987-12-10 1993-12-09 Wild Gmbh & Co Kg Rudolf Süßungsmittel
JP2670498B2 (ja) * 1988-03-04 1997-10-29 株式会社エスアールエル西日本 免疫複合体の測定法
DE69130217T2 (de) * 1990-04-06 1999-06-02 University Of Florida, Gainesville, Fla. Flüssigphasenimmundiagnostisches analysenverfahren
US5843794A (en) * 1992-03-26 1998-12-01 Montefiore Medical Center Technique for the prevention of false positive reactions in immunological testing due to C1 and C1q components of the complement and method for screening for rheumatic factor
JPH07500190A (ja) * 1992-03-26 1995-01-05 マントティフィオーレ、メディカル、センター 免疫試験中の誤反応を防止する技術
US5270169A (en) * 1992-06-23 1993-12-14 Sangstat Medical Corporation Detection of HLA antigen-containing immune complexes
WO1994017410A1 (en) * 1993-01-22 1994-08-04 Imre Corporation Improved immune complex assay
US5561049A (en) * 1994-09-21 1996-10-01 Behringwerke Ag Method for detecting antibodies
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
AT409801B (de) * 2000-05-31 2002-11-25 Cistem Biotechnologies Gmbh Verfahren zum screenen und isolieren von mikroorganismen, insbesondere prokaryontischer und eukaryontischer zellen, die ein antigen präsentieren
EP1298438A4 (en) * 2000-06-30 2006-12-13 Kyowa Medex Co Ltd NEUTROMETRIC IMMUNOLOGICAL DOSAGE REAGENT WITH PARTICLES-INSOLUBLE SUPPORTS
US9575070B2 (en) * 2001-12-04 2017-02-21 Wayne State University Neoepitope detection of disease using protein arrays
JPWO2004061452A1 (ja) * 2003-01-07 2006-05-18 株式会社医学生物学研究所 抗体の測定方法
US7799556B2 (en) * 2004-06-17 2010-09-21 George Dacai Liu System and method for antigen structure-independent detection of antigens captured on antibody arrays
DE102004052729A1 (de) * 2004-10-30 2006-05-04 Roche Diagnostics Gmbh Immunkomplex-spezifsicher Antikörper zur Reduktion des Nullwerts beim Nachweis von Antigen-spezifisch gebundenen Antikörpern einer bestimmten Immunglobulinklasse in Array-Testformaten
WO2012022774A1 (en) 2010-08-19 2012-02-23 Roche Diagnostics Gmbh An assay for measurement of antibodies binding to a therapeutic monoclonal antibody
JP5467365B2 (ja) * 2010-12-09 2014-04-09 パナソニック株式会社 抗原抗体複合体を分離する方法
CN107976535B (zh) * 2017-11-03 2020-03-20 科美诊断技术股份有限公司 一种检测样本中目标IgM抗体的均相免疫检测试剂盒及其使用方法和应用

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US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
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Also Published As

Publication number Publication date
JPS6022662A (ja) 1985-02-05
CH630465A5 (de) 1982-06-15
FR2272398B1 (it) 1981-08-21
JPS5126220A (it) 1976-03-04
NL182175C (nl) 1988-01-18
SE7505735L (sv) 1975-11-21
CH637770A5 (de) 1983-08-15
AU8133275A (en) 1976-11-25
DE2522087C2 (de) 1987-03-26
BE829278A (fr) 1975-11-20
NL7505867A (nl) 1975-11-24
SE435425B (sv) 1984-09-24
AU498364B2 (en) 1979-03-08
DE2522087A1 (de) 1975-12-11
DE2522086C2 (de) 1985-04-18
US4143124A (en) 1979-03-06
AU496821B2 (en) 1978-11-02
JPS5949545B2 (ja) 1984-12-03
FR2272398A1 (it) 1975-12-19
CH631015A5 (de) 1982-07-15
JPS6112224B2 (it) 1986-04-07
DE2560554C2 (de) 1985-04-18
BE829277A (fr) 1975-11-20
SE7807275L (sv) 1978-06-27
AU8133375A (en) 1976-11-25
JPS6110776B2 (it) 1986-03-31
NL7505868A (nl) 1975-11-24
IT1038305B (it) 1979-11-20
GB1508132A (en) 1978-04-19
DE2522086A1 (de) 1975-12-11
SE447606B (sv) 1986-11-24
SE435325B (sv) 1984-09-17
SE7505734L (sv) 1975-11-21
FR2272102B1 (it) 1979-05-04
JPS5126221A (it) 1976-03-04
SE7808314L (sv) 1978-08-01
JPS5915860A (ja) 1984-01-26
JPS598779B2 (ja) 1984-02-27
SE443660B (sv) 1986-03-03
US4062935A (en) 1977-12-13
FR2272102A1 (it) 1975-12-19

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