CH627188A5 - - Google Patents

Download PDF

Info

Publication number
CH627188A5
CH627188A5 CH319877A CH319877A CH627188A5 CH 627188 A5 CH627188 A5 CH 627188A5 CH 319877 A CH319877 A CH 319877A CH 319877 A CH319877 A CH 319877A CH 627188 A5 CH627188 A5 CH 627188A5
Authority
CH
Switzerland
Prior art keywords
methadone
derivative
antibody
sample
added
Prior art date
Application number
CH319877A
Other languages
German (de)
English (en)
Inventor
Magdalena Usategui Gomez
Harvey Gurien
John Edward Heveran
Manfred Weigele
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH627188A5 publication Critical patent/CH627188A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates

Landscapes

  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CH319877A 1976-10-13 1977-03-15 CH627188A5 (https=)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/731,620 US4104367A (en) 1976-10-13 1976-10-13 Radioimmunoassay for methadone

Publications (1)

Publication Number Publication Date
CH627188A5 true CH627188A5 (https=) 1981-12-31

Family

ID=24940277

Family Applications (1)

Application Number Title Priority Date Filing Date
CH319877A CH627188A5 (https=) 1976-10-13 1977-03-15

Country Status (9)

Country Link
US (1) US4104367A (https=)
JP (1) JPS5350144A (https=)
CA (1) CA1096774A (https=)
CH (1) CH627188A5 (https=)
DE (1) DE2716536C2 (https=)
GB (1) GB1574744A (https=)
IT (1) IT1075387B (https=)
NL (1) NL186116C (https=)
SE (1) SE447761B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901218A1 (de) * 1979-01-13 1980-07-17 Byk Gulden Lomberg Chem Fab Ung von theophyllin
US5089390A (en) * 1987-09-04 1992-02-18 Syntex (U.S.A.) Inc. 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US5073629A (en) * 1989-01-23 1991-12-17 Abbott Laboratories Methadone fluorescence polarization immunoassay
US5776783A (en) * 1993-11-02 1998-07-07 Private Clinic Laboratories, Inc. Method of monitoring therapeutic agent consumption
US5547878A (en) * 1993-11-02 1996-08-20 Kell; Michael Method of monitoring patient compliance with medications prescriptions
ATE245814T1 (de) * 1993-11-02 2003-08-15 U D Testing Inc Verffahren zum überwachen der befolgung einer vorgeschriebenen medikation durch einen patienten
US5955370A (en) * 1993-11-02 1999-09-21 U.D. Testing, Inc. Urine adulteration test method
US6124136A (en) * 1993-11-02 2000-09-26 U. D. Testing, Inc. Method of monitoring compliance with methadone treatment program
US5492841A (en) * 1994-02-18 1996-02-20 E. I. Du Pont De Nemours And Company Quaternary ammonium immunogenic conjugates and immunoassay reagents
US5710256A (en) * 1995-04-03 1998-01-20 Biosite Diagnostics Incorporated Methadone derivatives and protein and polypeptide methadone derivative conjugates and labels
JPH0918228A (ja) * 1995-06-30 1997-01-17 Nec Corp パラボラ空中線
ES2229341T3 (es) * 1997-05-27 2005-04-16 Microgenics Corporation Conjugados e inmunoensayos especificos para el metabolito de la metadona 2-etilidina-1,5-dimetil-3,3-difenil-pirrolidina.
US6136801A (en) * 1998-12-24 2000-10-24 U. D. Testing, Inc. Therapeutic agent with quantitative consumption marker
JP2025516687A (ja) * 2022-05-12 2025-05-30 ユニバーシティ オブ パドヴァ 中枢神経系（ｃｎｓ）効果及び末梢ｎｍｄａｒ遮断活性及び／又は免疫系調節効果を有する薬物のポリマーコンジュゲート

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2166716C3 (de) * 1970-05-13 1980-06-12 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Opiumalkaloid-Antigene und Verfahren zu ihrer Herstellung
IL39323A (en) * 1971-05-14 1975-08-31 Syva Co Highly sensitive assay method employing an enzyme for amplification
US3966556A (en) * 1972-11-06 1976-06-29 Syva Company Compounds for enzyme amplification assay methadone analogs

Also Published As

Publication number Publication date
NL186116B (nl) 1990-04-17
SE7704325L (sv) 1978-04-14
GB1574744A (en) 1980-09-10
NL186116C (nl) 1990-09-17
DE2716536C2 (de) 1985-03-21
IT1075387B (it) 1985-04-22
DE2716536A1 (de) 1978-04-20
SE447761B (sv) 1986-12-08
JPS6316709B2 (https=) 1988-04-11
US4104367A (en) 1978-08-01
CA1096774A (en) 1981-03-03
JPS5350144A (en) 1978-05-08
NL7704093A (nl) 1978-04-17

Similar Documents

Publication Publication Date Title
DE2202441C3 (https=)
DE69113114T2 (de) Test für Phencyclidin und Phencyclidin-Metaboliten, Tracer, Immunogene, Antikörper und Reagenzsatz dafür.
DE69332988T2 (de) Reagenzien zum Nachweis und zur Quantifizierung von Thyroxin in flüssigen Proben
DE2716536C2 (de) Methadon-Antigene und Verfahren zur Herstellung dieser
EP0013910B1 (de) Theophyllin-Antigene und -Antikörper, Verfahren zu deren Herstellung, ihre Verwendung zur Bestimmung von Theophyllin, Reagens-Set und Antiserum für diese Verwendung
DE69610716T2 (de) Topiramate-immunoassay, sowie analoge und antikörper
DE68913402T2 (de) Antikörper mit hoher Affinität für Methamphetamine sowie geeignetes Immunogen für seine Herstellung.
DE2910998A1 (de) Verfahren zur herstellung von gebundenes enzym enthaltenden produkten und deren verwendung
DE3856358T2 (de) Für Tests verwendbare chemilumineszierende Ester, Thioester und Amide
DE69332741T2 (de) Nachweis von hypoxia
DE2805663A1 (de) Verfahren zur herstellung von antigenen und antikoerpern
DE2539242A1 (de) Radioimmunologisches analyseverfahren zur bestimmung von digoxin
DE2627455A1 (de) Verfahren zur radioimmunologischen in-vitro-bestimmung von thyroxin und abgepacktes testbesteck zur durchfuehrung dieses verfahrens
EP0183901B1 (de) Bifunktionelle Haptene, Verfahren zu ihrer Herstellung und ihre Verwendung
DE2548196A1 (de) Antigene auf basis von methaqualon- hapten sowie deren verwendung
DE4329952C1 (de) Monoklonale Antikörper zum Nachweis von Pyrethroiden sowie Verfahren zu deren Herstellung
DE69731649T2 (de) Konjugate und spezifische immuntests des methadonmetaboliten 2-ethylidin-1,5-dimethyl-3,3-diphenyl-3,3-diphenylpyrrolidin
DE3129705A1 (de) Mit dichlortriazinylaminofluorescein markierte verbindungen von biologischem interesse
DE2310280A1 (de) Tubocurarin-antigene
DE2607826A1 (de) Verfahren zur radioimmunologischen in-vitro-bestimmung von kardiotenischen glykosiden und abgepacktes testbesteck zur durchfuehrung dieses verfahrens
DE3025226A1 (de) Radioimmunoassay zur bestimmung von pterinen und neue dafuer verwendbare pterinderivate
DE2738156A1 (de) Bestimmung von catecholaminen
DE69023357T2 (de) Fluoreszenz-Polarisationsimmunoassay für Methadon.
DE3114362C2 (de) Verfahren zur Herstellung eines Antikörpers bzw. Antiserums, Verwendung dieses Verfahrens zur Gewinnung von Säugetierzellen, welche fähig sind, einen solchen Antikörper zu erzeugen und Verwendung des so hergestellten Antikörpers bzw. Antiserums zur Immunoprüfung
EP0303284B2 (de) Immunologisches Bestimmungsverfahren zur Bestimmung von Hapteneigenschaften aufweisenden freien Substanzen

Legal Events

Date Code Title Description
PUE Assignment

Owner name: F. HOFFMANN-LA ROCHE AG

PL Patent ceased
PL Patent ceased