CH626535A5 - - Google Patents

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Publication number
CH626535A5
CH626535A5 CH504776A CH504776A CH626535A5 CH 626535 A5 CH626535 A5 CH 626535A5 CH 504776 A CH504776 A CH 504776A CH 504776 A CH504776 A CH 504776A CH 626535 A5 CH626535 A5 CH 626535A5
Authority
CH
Switzerland
Prior art keywords
ascorbic acid
reagent
acid
added
technetium
Prior art date
Application number
CH504776A
Other languages
German (de)
English (en)
Inventor
Harry S Winchell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH626535A5 publication Critical patent/CH626535A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH504776A 1975-04-30 1976-04-22 CH626535A5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/573,297 US4364920A (en) 1975-04-30 1975-04-30 Stable diagnostic reagents

Publications (1)

Publication Number Publication Date
CH626535A5 true CH626535A5 (xx) 1981-11-30

Family

ID=24291411

Family Applications (1)

Application Number Title Priority Date Filing Date
CH504776A CH626535A5 (xx) 1975-04-30 1976-04-22

Country Status (10)

Country Link
US (1) US4364920A (xx)
JP (1) JPS51148038A (xx)
BE (1) BE841261A (xx)
CA (1) CA1114291A (xx)
CH (1) CH626535A5 (xx)
DE (1) DE2619382A1 (xx)
DK (1) DK156540C (xx)
FR (1) FR2309215A1 (xx)
GB (1) GB1489330A (xx)
NL (1) NL189336C (xx)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075314A (en) * 1976-04-29 1978-02-21 Mallinckrodt, Inc. Stannous pyrophosphate technetium-99m compositions
US4247534A (en) * 1978-07-31 1981-01-27 The Procter & Gamble Company Radiographic scanning agent
JPS55180577U (xx) * 1979-06-15 1980-12-25
JPS5750928A (en) * 1980-09-13 1982-03-25 Nippon Mejifuijitsukusu Kk Diagnostic agent for scanning bone
DE3274621D1 (en) * 1981-10-30 1987-01-22 Amersham Int Plc Radiopharmaceutical composition based on technetium-99m and reagent for making it
JPS5896031A (ja) * 1981-12-03 1983-06-07 Nippon Mejifuijitsukusu Kk 放射性診断剤およびその製造用組成物
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
US4454106A (en) * 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
US4440738A (en) * 1982-06-10 1984-04-03 Mallinckrodt, Inc. Stable radiographic imaging agents
EP0096931B1 (en) * 1982-06-10 1987-03-25 Mallinckrodt, Inc. (a Delaware corporation) Radiographic imaging agents
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4504463A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
ATE23800T1 (de) * 1982-06-10 1986-12-15 Mallinckrodt Inc Roentgen-sichtbarmachungsmittel.
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
US4510125A (en) * 1982-12-08 1985-04-09 Mallinckrodt, Inc. Process for making lyophilized radiographic imaging kit
EP0111414A3 (en) * 1982-12-08 1985-05-02 Mallinckrodt, Inc. (a Delaware corporation) Radiographic imaging agents
JPS59199636A (ja) * 1983-04-26 1984-11-12 Nippon Mejifuijitsukusu Kk 放射性診断剤
US4574079A (en) * 1983-05-27 1986-03-04 Gavras Haralambos P Radiolabeled angiotensin converting enzyme inhibitors for radiolabeling mammalian organ sites
US4647445A (en) * 1984-03-28 1987-03-03 Massachusetts Institute Of Technology Radiolabelled lipoproteins and method for making same
JPS61103841A (ja) * 1984-10-26 1986-05-22 Nippon Mejifuijitsukusu Kk 放射性テクネチウム標識に供する安定な塩化第一スズ組成物
US4897255A (en) * 1985-01-14 1990-01-30 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US5393512A (en) * 1985-01-14 1995-02-28 Vanderheyden; Jean-Luc Stable therapeutic radionuclide compositions and methods for preparation thereof
DE3621570A1 (de) * 1986-06-27 1988-01-07 Hoechst Ag Diagnostikum zur szintigraphischen darstellung von boesartigen tumoren
US4880615A (en) * 1988-11-25 1989-11-14 Merck & Co., Inc. Stabilized radiopharmaceutical compositions
CA2066779A1 (en) * 1989-09-22 1991-03-23 Jean-Luc Vanderheyden Stable therapeutic radionuclide compositions and methods for preparation thereof
US5306482A (en) * 1991-04-09 1994-04-26 Merck Frosst Canada, Inc. Radiopharmaceutical bacteriostats
AU2541592A (en) * 1991-08-01 1993-03-02 Hybritech Incorporated Improvements in or relating to modified haptens useful as imaging and therapeutic agents
DE4332479A1 (de) * 1993-09-24 1995-03-30 Theodor Prasso Wasserkraftanlage zur Ausnutzung von Kleingefälle
US6027710A (en) * 1996-09-18 2000-02-22 Nihon Medi-Physiscs Co., Ltd. Radiation-protecting agent
US6231832B1 (en) 1998-03-23 2001-05-15 Brookhaven Science Associates Radiopharmaceutical stannic Sn-117m chelate compositions and methods of use
WO1999051276A1 (en) * 1998-04-01 1999-10-14 Australian Nuclear Science & Technology Organisation Tin-free rhenium(v) complexes and methods for their preparation
GB0031592D0 (en) * 2000-12-28 2001-02-07 Nycomed Amersham Plc Stabilised radiopharmaceutical compositions
US7556795B2 (en) * 2002-05-03 2009-07-07 Bracco Imaging S.P.A. Radiopharmaceutical formulations
EP1444990A1 (en) 2003-02-07 2004-08-11 Amersham plc Improved Radiometal Complex Compositions
BRPI0412824A (pt) * 2003-07-24 2006-09-26 Bracco Imaging Spa composições radiofarmacêuticas estáveis e métodos para suas preparações
GB0718386D0 (en) * 2007-09-21 2007-10-31 Ge Healthcare As Improved radiopharmaceutical formulation
US20100196272A1 (en) * 2009-01-30 2010-08-05 Neoprobe Corporation Compositions for radiolabeling diethylenetriaminepentaacetic acid (dtpa)-dextran
FR2967671A1 (fr) * 2010-11-24 2012-05-25 Pf Medicament Complexe de technetium 99m en tant qu'outil de diagnostic in vivo des tumeurs cancereuses

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2088149B1 (xx) * 1970-05-22 1974-05-24 Philips France
US3740418A (en) * 1970-07-01 1973-06-19 Squibb & Sons Inc Radioactive scanning preparation
US3725295A (en) * 1971-07-20 1973-04-03 Atomic Energy Commission Technetium labeling
US3902849A (en) * 1971-08-19 1975-09-02 Medi Physics Inc Radioisotope and radiopharmaceutical generators
AU5527973A (en) * 1972-05-08 1974-11-07 Solco Basel Ag PROCESS FORTHE MANUFACTURE OF INJECTABLE PREPARATIONS OF Tc99m AND/OR In113m AND APPARATUS FOR CARRYING OUT THE PROCESS
CH566138A5 (en) * 1972-05-08 1975-09-15 Benes Ivan Diagnostic solns contg technetium 99 or indium 113 - from solns of low concn
US3735001A (en) * 1972-05-24 1973-05-22 Atomic Energy Commission Technetium bone scanning medium
ZA743158B (en) * 1973-05-23 1975-05-28 Procter & Gamble Radiographic scanning

Also Published As

Publication number Publication date
GB1489330A (en) 1977-10-19
US4364920A (en) 1982-12-21
DK156540C (da) 1990-02-05
CA1114291A (en) 1981-12-15
DE2619382A1 (de) 1976-11-11
DE2619382C2 (xx) 1988-09-01
JPS576409B2 (xx) 1982-02-04
JPS51148038A (en) 1976-12-18
NL189336B (nl) 1992-10-16
NL189336C (nl) 1993-03-16
BE841261A (fr) 1976-10-29
NL7604475A (nl) 1976-11-02
DK156540B (da) 1989-09-11
FR2309215B1 (xx) 1979-09-28
DK156976A (da) 1976-10-31
FR2309215A1 (fr) 1976-11-26

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: F. HOFFMANN-LA ROCHE AG

PUE Assignment

Owner name: AMERSHAM INTERNATIONAL PLC

PL Patent ceased