CH626057A5 - - Google Patents

Download PDF

Info

Publication number
CH626057A5
CH626057A5 CH334576A CH334576A CH626057A5 CH 626057 A5 CH626057 A5 CH 626057A5 CH 334576 A CH334576 A CH 334576A CH 334576 A CH334576 A CH 334576A CH 626057 A5 CH626057 A5 CH 626057A5
Authority
CH
Switzerland
Prior art keywords
oxime
compounds
salts
aminoethyl
pharmaceutically acceptable
Prior art date
Application number
CH334576A
Other languages
German (de)
English (en)
Inventor
Hendricus Bernardus Anto Welle
Volkert Claassen
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of CH626057A5 publication Critical patent/CH626057A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH334576A 1975-03-20 1976-03-17 CH626057A5 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7503310A NL7503310A (nl) 1975-03-20 1975-03-20 Verbindingen met antidepressieve werking.

Publications (1)

Publication Number Publication Date
CH626057A5 true CH626057A5 (cs) 1981-10-30

Family

ID=19823424

Family Applications (4)

Application Number Title Priority Date Filing Date
CH334576A CH626057A5 (cs) 1975-03-20 1976-03-17
CH153981A CH629184A5 (de) 1975-03-20 1981-03-06 Verfahren zur herstellung neuer oximaetherverbindungen.
CH154181A CH629761A5 (de) 1975-03-20 1981-03-06 Verfahren zur herstellung neuer oximaetherverbindungen.
CH154081A CH629477A5 (de) 1975-03-20 1981-03-06 Verfahren zur herstellung neuer oximaetherverbindungen.

Family Applications After (3)

Application Number Title Priority Date Filing Date
CH153981A CH629184A5 (de) 1975-03-20 1981-03-06 Verfahren zur herstellung neuer oximaetherverbindungen.
CH154181A CH629761A5 (de) 1975-03-20 1981-03-06 Verfahren zur herstellung neuer oximaetherverbindungen.
CH154081A CH629477A5 (de) 1975-03-20 1981-03-06 Verfahren zur herstellung neuer oximaetherverbindungen.

Country Status (27)

Country Link
US (1) US4085225A (cs)
JP (1) JPS6026776B2 (cs)
AR (2) AR211011A1 (cs)
AT (1) AT340895B (cs)
AU (1) AU505358B2 (cs)
BE (1) BE839744A (cs)
CA (1) CA1076142A (cs)
CH (4) CH626057A5 (cs)
DD (1) DD128332A5 (cs)
DE (1) DE2610886A1 (cs)
DK (1) DK144942C (cs)
ES (1) ES446192A1 (cs)
FI (1) FI61875C (cs)
FR (1) FR2304336A1 (cs)
GB (1) GB1535226A (cs)
GR (1) GR60052B (cs)
HU (1) HU171030B (cs)
IE (1) IE43768B1 (cs)
IL (1) IL49238A (cs)
IT (1) IT1063064B (cs)
MX (1) MX9203723A (cs)
NL (1) NL7503310A (cs)
PL (3) PL100052B1 (cs)
SE (1) SE410312B (cs)
SU (3) SU635867A3 (cs)
YU (1) YU39345B (cs)
ZA (1) ZA761434B (cs)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
ES2145977T3 (es) * 1995-08-16 2000-07-16 Lilly Co Eli Potenciacion de la respuesta de la serotonina.
IN182588B (cs) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IE990406A1 (en) 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
IN186677B (cs) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
AU2001257022B2 (en) * 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
EP1276478A2 (en) * 2000-04-24 2003-01-22 ARYx Therapeutics (2-aminoethyl) oxime derivatives for the treatment of depression
US7256191B2 (en) * 2000-04-24 2007-08-14 Aryx Therapeutics Materials and methods for the treatment of depression
ES2666188T3 (es) * 2001-10-12 2018-05-03 Azevan Pharmaceuticals, Inc. Antagonistas del v1a de vasopresina beta-lactámicos
KR20040088519A (ko) 2002-02-22 2004-10-16 뉴 리버 파마슈티칼스, 인크. 활성 제제 전달 시스템 및 활성 제제의 보호 및 투여 방법
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
EP1651195A4 (en) * 2003-07-11 2007-10-03 Myriad Genetics Inc PHARMACEUTICAL PROCESSES, DOSIERSCHEMATA AND DOSAGE FORMS FOR THE TREATMENT OF ALZHEIMER DISEASE
CA2537402C (en) 2003-09-12 2009-05-05 Pfizer Inc. Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
DE602004028150D1 (de) * 2003-11-26 2010-08-26 Pfizer Prod Inc Aminopyrazolderivate als gsk-3-inhibitoren
PT1691811E (pt) 2003-12-11 2014-10-30 Sunovion Pharmaceuticals Inc Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
CA2567249A1 (en) * 2004-04-19 2006-10-05 Jds Pharmaceuticals, Llc Lithium combinations, and uses related thereto
WO2005108683A1 (en) * 2004-04-29 2005-11-17 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CA2618985A1 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
AU2006227199A1 (en) 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
AU2006239897A1 (en) * 2005-04-22 2006-11-02 Wyeth Crystal forms of {[(2R)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
CN101203216A (zh) * 2005-04-22 2008-06-18 惠氏公司 二氢苯并呋喃衍生物及其用途
CA2605554A1 (en) * 2005-04-22 2006-11-02 Wyeth Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists
CN101175740A (zh) 2005-04-22 2008-05-07 惠氏公司 二氢苯并呋喃衍生物和其用途
NZ565683A (en) * 2005-07-08 2011-04-29 Braincells Inc Methods for identifying agents and conditions that modulate neurogenesis in human neural cells
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
RU2466991C2 (ru) * 2005-07-19 2012-11-20 Эйзеван Фармасьютиклз, Инк. β-ЛАКТАМИЛЗАМЕЩЕННЫЕ АНАЛОГИ ФЕНИЛАЛАНИНА, ЦИСТЕИНА И СЕРИНА В КАЧЕСТВЕ АНТАГОНИСТОВ ВАЗОПРЕССИНА
US20070042034A1 (en) * 2005-07-22 2007-02-22 Myriad Genetics, Incorporated High drug load formulations and dosage forms
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
PA8720801A1 (es) * 2006-03-24 2008-11-19 Wyeth Corp Nuevas combinaciones terapeuticas para el tratamiento de la depresion
JP4615470B2 (ja) * 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
EP2046119A2 (en) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Treatment of psychiatric disorders
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス，インコーポレイティド ４−アシルアミノピリジン誘導体を含む組み合わせ
WO2008034032A2 (en) * 2006-09-14 2008-03-20 Azevan Pharmaceuticals, Inc. Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080167363A1 (en) * 2006-12-28 2008-07-10 Braincells, Inc Modulation of Neurogenesis By Melatoninergic Agents
EP2125017A2 (en) * 2007-01-11 2009-12-02 Braincells, Inc. Modulation of neurogenesis with use of modafinil
US20110034565A1 (en) 2008-04-18 2011-02-10 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
KR101859409B1 (ko) 2009-10-23 2018-05-18 얀센 파마슈티카 엔.브이. 오렉신 수용체 조절제로서의 이치환된 옥타하이드로피롤로［3,4-ｃ］피롤
EP2509596B1 (en) 2009-12-08 2019-08-28 Case Western Reserve University Gamma aminoacids for treating ocular disorders
ES2858499T3 (es) 2010-07-01 2021-09-30 Azevan Pharmaceuticals Inc Compuestos para su uso en el tratamiento de trastorno explosivo intermitente
BR112013023810A2 (pt) 2011-03-17 2016-12-13 Lupin Ltd composições farmacêuticas de liberação controlada de inibidores seletivos da recaptação de serotonina
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
IN2013MU01290A (cs) 2013-04-03 2015-04-10 Zcl Chemicals Ltd
WO2015118365A1 (en) 2014-02-07 2015-08-13 Mta Támogatott Kutatócsoportok Irodája Novel use of sigma-1 receptor agonist compounds
SG10202001065SA (en) 2014-03-28 2020-04-29 Azevan Pharmaceuticals Inc Compositions and methods for treating neurodegenerative diseases
SG11201807597UA (en) 2016-03-10 2018-10-30 Janssen Pharmaceutica Nv Methods of treating depression using orexin-2 receptor antagonists
CN110337244B (zh) 2016-11-24 2023-07-21 西格玛研究有限责任公司 用于器官保藏的组合物
CA3075759A1 (en) 2017-09-15 2019-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury
JP7739256B2 (ja) 2019-07-19 2025-09-16 バイオエクセル セラピューティクス，インコーポレイテッド 鎮静作用のないデクスメデトミジン治療レジメン
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes

Also Published As

Publication number Publication date
YU71476A (en) 1982-10-31
GR60052B (en) 1978-04-04
JPS51125345A (en) 1976-11-01
DE2610886C2 (cs) 1987-09-24
CH629477A5 (de) 1982-04-30
IE43768B1 (en) 1981-05-20
DE2610886A1 (de) 1976-10-07
SE410312B (sv) 1979-10-08
FI61875C (fi) 1982-10-11
AU505358B2 (en) 1979-11-15
MX9203723A (es) 1992-07-01
CH629184A5 (de) 1982-04-15
CA1076142A (en) 1980-04-22
SU645559A3 (ru) 1979-01-30
PL101951B1 (pl) 1979-02-28
SU635867A3 (ru) 1978-11-30
IL49238A0 (en) 1976-05-31
FI760699A7 (cs) 1976-09-21
DK144942C (da) 1982-12-06
PL100052B1 (pl) 1978-08-31
DD128332A5 (de) 1977-11-09
GB1535226A (en) 1978-12-13
IL49238A (en) 1978-08-31
DK144942B (da) 1982-07-12
JPS6026776B2 (ja) 1985-06-25
CH629761A5 (de) 1982-05-14
NL7503310A (nl) 1976-09-22
SE7603341L (sv) 1976-09-21
HU171030B (hu) 1977-10-28
AU1214776A (en) 1977-09-22
PL100614B1 (pl) 1978-10-31
SU620206A3 (ru) 1978-08-15
AR211011A1 (es) 1977-10-14
DK115976A (da) 1976-09-21
AR211153A1 (es) 1977-10-31
FR2304336B1 (cs) 1979-09-28
FI61875B (fi) 1982-06-30
ATA195476A (de) 1977-05-15
IE43768L (en) 1976-09-20
ZA761434B (en) 1977-10-26
ES446192A1 (es) 1977-10-01
US4085225A (en) 1978-04-18
BE839744A (fr) 1976-09-20
AT340895B (de) 1978-01-10
FR2304336A1 (fr) 1976-10-15
YU39345B (en) 1984-10-31
IT1063064B (it) 1985-02-11

Similar Documents

Publication Publication Date Title
CH626057A5 (cs)
CH616676A5 (cs)
CH615677A5 (cs)
DE2305092C2 (cs)
CH622507A5 (en) Process for the preparation of 1,4-dihydropyridines
CH626062A5 (cs)
CH622501A5 (cs)
DE2610679C2 (de) Sulfinylgruppenhaltige Oximätherderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Mittel
CH626056A5 (cs)
DE2353160C2 (de) 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine, ihre Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
DE2034588C3 (de) 6,7-Dimethoxy-4-benzylisochinoline, Verfahren zu ihrer Herstellung und Arzneimittel
DD148633A5 (de) Verfahren zur herstellung von hexahydro-1,4-oxazepinen
DE2348577A1 (de) L-amino-4-phenyltetralin-derivate und diese enthaltende pharmazeutische zubereitung
DE2244737B2 (de) H-o-ChlorphenyD-2-tert-butylaminoäthanol, Verfahren zu dessen Herstellung und Arzneimittel auf dessen Basis
DE2421549A1 (de) Naphthalinderivate, verfahren zu ihrer herstellung und arzneimittel
DE2615129A1 (de) Tripeptide, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE69621706T2 (de) Verwendung von Piperazinverbindungen als narkotische Antagonisten
DE2003353B2 (de) Phenylisopropylaminoäthanol-Derivate, deren Herstellungsverfahren und Arzneimittel auf deren Basis
DE2538593C3 (de) m-Trifluormethylthio-phenäthylaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2810482A1 (de) 1-phenyl-2- eckige klammer auf (n-alkyl)-amino eckige klammer zu -propan-1,3-diole, solche enthaltende arzneimittel und verfahren zur herstellung derselben
AT278785B (de) Verfahren zur Herstellung von neuen Piperidinderivaten und ihren Salzen
DE2022790C3 (de) 10-Methyl-5-[ (4-Methylpiperazino)-acetyl J-5,10dihydro-llH-dibenzo [b,e ] [1,4 ] diazepin-11-on, ein Verfahren zu dessen Herstellung sowie dieses enthaltende Arzneimittel
DE2518514A1 (de) 1,3,4-trimethyl-2-(3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridin, verfahren zu seiner herstellung sowie es enthaltende arzneimittel
CH454147A (de) Verfahren zur Herstellung eines neuen Isoxazolderivates
DE2538593B2 (de) M-trifluormethylthio-phenaethylaminderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Legal Events

Date Code Title Description
PL Patent ceased
SPCF Supplementary protection certificate filed

Free format text: IKS 44603/830713, 960221

SPCG Supplementary protection certificate granted

Free format text: IKS 44603/830713, 960221, EXPIRES:19980713