CH625226A5 - - Google Patents

Download PDF

Info

Publication number
CH625226A5
CH625226A5 CH846880A CH846880A CH625226A5 CH 625226 A5 CH625226 A5 CH 625226A5 CH 846880 A CH846880 A CH 846880A CH 846880 A CH846880 A CH 846880A CH 625226 A5 CH625226 A5 CH 625226A5
Authority
CH
Switzerland
Prior art keywords
acid
iminodibenzyl
cyano
formula
dimethylaminopropyl
Prior art date
Application number
CH846880A
Other languages
German (de)
English (en)
Inventor
Philippe Dr Dostert
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH625226A5 publication Critical patent/CH625226A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CH846880A 1976-10-12 1980-11-14 CH625226A5 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1287676A CH623574A5 (da) 1976-10-12 1976-10-12

Publications (1)

Publication Number Publication Date
CH625226A5 true CH625226A5 (da) 1981-09-15

Family

ID=4387222

Family Applications (4)

Application Number Title Priority Date Filing Date
CH1287676A CH623574A5 (da) 1976-10-12 1976-10-12
CH847080A CH627169A5 (da) 1976-10-12 1980-11-14
CH846880A CH625226A5 (da) 1976-10-12 1980-11-14
CH846980A CH625227A5 (da) 1976-10-12 1980-11-14

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH1287676A CH623574A5 (da) 1976-10-12 1976-10-12
CH847080A CH627169A5 (da) 1976-10-12 1980-11-14

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH846980A CH625227A5 (da) 1976-10-12 1980-11-14

Country Status (32)

Country Link
US (1) US4138482A (da)
JP (1) JPS5346991A (da)
AR (1) AR216106A1 (da)
AT (1) AT362378B (da)
AU (1) AU512561B2 (da)
BE (1) BE859569A (da)
CA (1) CA1075688A (da)
CH (4) CH623574A5 (da)
DE (1) DE2745280C2 (da)
DK (1) DK153786C (da)
ES (1) ES463133A1 (da)
FI (1) FI62531C (da)
FR (1) FR2367749A1 (da)
GB (1) GB1583590A (da)
GR (1) GR66109B (da)
HK (1) HK26384A (da)
HU (1) HU173607B (da)
IE (1) IE45709B1 (da)
IL (1) IL53074A (da)
IT (1) IT1143697B (da)
LU (1) LU78280A1 (da)
MC (1) MC1169A1 (da)
MY (1) MY8500097A (da)
NL (1) NL183943C (da)
NO (1) NO145135C (da)
NZ (1) NZ185378A (da)
PH (1) PH13371A (da)
PT (1) PT67142B (da)
SE (1) SE427557B (da)
SG (1) SG60983G (da)
YU (1) YU40482B (da)
ZA (1) ZA775974B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370324A (en) * 1980-09-17 1983-01-25 Bernstein Joel E Method and composition for treating and preventing irritation of the eyes
US4505909A (en) * 1980-09-17 1985-03-19 Bernstein Joel E Method and composition for treating and preventing irritation of the eyes
JPH03129724U (da) * 1990-04-09 1991-12-26
US10639313B2 (en) 2017-09-01 2020-05-05 Ndsu Research Foundation Compound for inhibition of delta-5-desaturase (D5D) and treatment of cancer and inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK34863C (da) * 1924-09-12 1925-08-17 Carl Christian Marius Nielsen Anordning ved Bagagebærere til Cykler, Motorcykler og lignende.
DK93077C (da) * 1958-12-06 1962-03-26 Geigy Ag J R Fremgangsmåde til fremstilling af 5H-dibenzo[b,f]azepinforbindelser eller 10,11-dihydroforbindelser heraf eller salte heraf.
CH375360A (de) * 1959-01-12 1964-02-29 Geigy Ag J R Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen
FR1359676A (fr) * 1963-01-14 1964-04-30 Rhone Poulenc Sa Nouveau procédé d'aminoalcoylation d'amines hétérocycliques
FR84219E (fr) 1963-01-14 1964-12-24 Rhone Poulenc Sa Nouveau procédé d'aminoalcoylation d'amines hétérocycliques

Also Published As

Publication number Publication date
SG60983G (en) 1985-01-11
MC1169A1 (fr) 1978-06-02
DE2745280C2 (de) 1986-02-06
GR66109B (da) 1981-01-16
FI772675A (fi) 1978-04-13
NO773473L (no) 1978-04-13
ES463133A1 (es) 1979-01-01
ZA775974B (en) 1978-08-30
DK153786B (da) 1988-09-05
PH13371A (en) 1980-03-20
NL7710194A (nl) 1978-04-14
PT67142B (pt) 1979-11-12
IE45709B1 (en) 1982-11-03
NO145135C (no) 1982-01-20
NZ185378A (en) 1980-03-05
IE45709L (en) 1978-04-12
CA1075688A (en) 1980-04-15
GB1583590A (en) 1981-01-28
HK26384A (en) 1984-03-30
CH627169A5 (da) 1981-12-31
NL183943C (nl) 1989-03-01
FR2367749A1 (fr) 1978-05-12
YU40482B (en) 1986-02-28
NL183943B (nl) 1988-10-03
FR2367749B1 (da) 1982-03-26
IL53074A (en) 1981-10-30
PT67142A (pt) 1977-11-01
SE7711433L (sv) 1978-04-13
HU173607B (hu) 1979-06-28
IT1143697B (it) 1986-10-22
JPS5346991A (en) 1978-04-27
YU220977A (en) 1983-12-31
CH625227A5 (da) 1981-09-15
ATA726177A (de) 1980-10-15
US4138482A (en) 1979-02-06
FI62531C (fi) 1983-01-10
MY8500097A (en) 1985-12-31
DE2745280A1 (de) 1978-04-13
LU78280A1 (da) 1979-02-02
AR216106A1 (es) 1979-11-30
DK153786C (da) 1989-01-23
JPS6229428B2 (da) 1987-06-25
SE427557B (sv) 1983-04-18
AU512561B2 (en) 1980-10-16
IL53074A0 (en) 1977-12-30
NO145135B (no) 1981-10-12
BE859569A (fr) 1978-04-11
CH623574A5 (da) 1981-06-15
AU2939177A (en) 1979-04-12
DK451477A (da) 1978-04-13
AT362378B (de) 1981-05-11
FI62531B (fi) 1982-09-30

Similar Documents

Publication Publication Date Title
CH637935A5 (de) Verfahren zur herstellung neuer derivate von perhydro-aza-heterocyclen.
DE2234651B2 (de) Eckige klammer auf 1-(p-chlorbenzoyl)- 5-methoxy-2-methyl-3-indol eckige klammer zu -acetoxyessigsaeure, ihre salze mit basen, verfahren zu ihrer herstellung sowie pharmakologische zubereitungen
DE1220425B (de) Verfahren zur Herstellung des lokalanaesthetisch wirksamen N-[1'-Benzyl-piperidyl-(4')]-naphthalin-1, 8-dicarbonsaeureimids
DE2851416C2 (da)
CH625226A5 (da)
DE2463088C1 (de) Substituierte Thienylverbindungen,Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0082461B1 (de) Substituierte Phenoxyalkanolamine und Phenoxyalkanol-cycloalkylamine, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende pharmazeutische Zubereitungen und Zwischenprodukte
EP0005821B1 (de) Indanaminderivate, Verfahren zur Herstellung derselben und Arzneimittel, welche diese enthalten
DE2535599C2 (de) Substituierte Zimtsäureamide, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen, welche diese Verbindungen enthalten
AT363485B (de) Verfahren zur herstellung des neuen 3-cyan-n-(n,n-dimethylaminopropyl)-iminodibenzyls und dessen saeureadditionssalzen
DE3104883C2 (de) Benzylidenderivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
AT375345B (de) Verfahren zur herstellung des neuen 3-cyan-n-(n,n-dimethylaminopropyl)-iminodibenzy s und dessen saeureadditionssalzen
CH633522A5 (de) N-(3-trifluormethylphenyl)-anthranilsaeurealkylester und verfahren zu ihrer herstellung.
DE2624177A1 (de) Verfahren zur herstellung von m-benzoylhydratropsaeure
CH523884A (de) Verfahren zur Herstellung neuer Indol-Derivate
DE1095283B (de) Verfahren zur Herstellung von Phenthiazinderivaten
EP0003298A2 (de) 4-Hydroxy-2-benzimidazolin-thion-Derivate, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel
DE2632114C3 (de) Cyclopentancarbonsaureverbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Mittel
AT360018B (de) Verfahren zur herstellung des neuen 4-(7-brom-5 -methoxy-2-benzofuranyl)- piperidins und seiner saeureadditionssalze
DE1154806B (de) Verfahren zur Herstellung von Phenthiazinderivaten
DE2329815C3 (de) Pharmazeutisches Mittel zur Behandlung von Atherosklerose, Thrombose und Hämorrhagie
DE2410307C2 (de) 2-(2-Thioäthyl)-4-carboxy-thiazolidin-Derivate
CH617177A5 (da)
AT217465B (de) Verfahren zur Herstellung neuer Ester der Indol-Reihe
DE1953342C3 (de) 1 -(3-Cyan-3,3-diphenylpropy1)-4phenylisonipecotinsäure

Legal Events

Date Code Title Description
PUE Assignment

Owner name: F. HOFFMANN-LA ROCHE AG

PL Patent ceased