CH624956A5 - Verfahren zur entfernung von verunreinigungen aus clavulansaeure. - Google Patents
Verfahren zur entfernung von verunreinigungen aus clavulansaeure. Download PDFInfo
- Publication number
- CH624956A5 CH624956A5 CH148776A CH148776A CH624956A5 CH 624956 A5 CH624956 A5 CH 624956A5 CH 148776 A CH148776 A CH 148776A CH 148776 A CH148776 A CH 148776A CH 624956 A5 CH624956 A5 CH 624956A5
- Authority
- CH
- Switzerland
- Prior art keywords
- salt
- lithium
- clavulanic acid
- water
- clavulanate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB540975A GB1543563A (en) | 1975-02-07 | 1975-02-07 | Beta-lactam antibiotic in purified form |
GB1107675 | 1975-03-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH624956A5 true CH624956A5 (de) | 1981-08-31 |
Family
ID=26239868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH148776A CH624956A5 (de) | 1975-02-07 | 1976-02-06 | Verfahren zur entfernung von verunreinigungen aus clavulansaeure. |
Country Status (15)
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ177159A (en) * | 1974-04-20 | 1978-03-06 | Beecham Group Ltd | Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions |
GB1542405A (en) * | 1975-04-15 | 1979-03-21 | Beecham Group Ltd | Clavulanic acid derivatives |
DE2862254D1 (en) * | 1977-12-02 | 1983-06-16 | Beecham Group Plc | A process for the preparation of ether derivatives of clavulanic acid |
DE3063683D1 (en) * | 1979-08-24 | 1983-07-14 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
GB9702216D0 (en) * | 1997-02-04 | 1997-03-26 | Smithkline Beecham Plc | Novel product |
GB9702218D0 (en) * | 1997-02-04 | 1997-03-26 | Smithkline Beecham Plc | Novel product |
ES2142641T3 (es) * | 1997-03-24 | 2000-04-16 | Cipan Comp Ind Prod | Procedimiento para aislar una sal alcalino-metalica farmaceuticamente aceptable del acido clavulanico. |
JPH11254368A (ja) * | 1998-03-12 | 1999-09-21 | Central Motor Co Ltd | 部材保持装置 |
AU5409799A (en) * | 1998-07-03 | 2000-01-24 | Dsm N.V. | Fermentation process to produce clavulanic acid at a low concentration of free amino acids |
PT102181A (pt) * | 1998-07-20 | 2000-01-31 | Dsm Nv | Processo melhorado para a producao de acido clavulanico |
JP3737801B2 (ja) * | 2000-10-05 | 2006-01-25 | テバ ジョジセルジャール レースベニュタールシャシャーグ | プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウム、並びにそれを含む組成物 |
US20040072815A1 (en) * | 2002-02-12 | 2004-04-15 | Koppel Gary A. | Antibiotic composition and method |
KR100461278B1 (ko) * | 2002-10-23 | 2004-12-10 | 현대자동차주식회사 | 용접 대상물의 위치규제 및 취출장치 |
EP3692159A1 (en) | 2017-10-02 | 2020-08-12 | Metabolic Explorer | Method for producing organic acid salts from fermentation broth |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE754693A (fr) * | 1969-08-12 | 1971-02-11 | Lilly Co Eli | Nouvel antibiotique et procede pour le preparer |
NZ177159A (en) * | 1974-04-20 | 1978-03-06 | Beecham Group Ltd | Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions |
JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
-
1976
- 1976-02-06 YU YU290/76A patent/YU40452B/xx unknown
- 1976-02-06 FR FR7603281A patent/FR2368276A1/fr active Granted
- 1976-02-06 DK DK49876AA patent/DK141099B/da not_active IP Right Cessation
- 1976-02-06 AT AT83476A patent/AT353409B/de not_active IP Right Cessation
- 1976-02-06 IT IT7647988A patent/IT1059403B/it active Protection Beyond IP Right Term
- 1976-02-06 AU AU10891/76A patent/AU509313B2/en not_active Expired
- 1976-02-06 ES ES76444948A patent/ES444948A1/es not_active Expired
- 1976-02-06 IE IE245/76A patent/IE43790B1/en unknown
- 1976-02-06 DE DE19762604697 patent/DE2604697A1/de active Granted
- 1976-02-06 SE SE7601337A patent/SE421796B/xx not_active IP Right Cessation
- 1976-02-06 FI FI760285A patent/FI63580C/fi not_active IP Right Cessation
- 1976-02-06 CH CH148776A patent/CH624956A5/de not_active IP Right Cessation
- 1976-02-06 JP JP51012156A patent/JPS51101994A/ja active Pending
- 1976-02-06 NL NL7601227A patent/NL7601227A/xx active Search and Examination
- 1976-02-09 IT IT7648002A patent/IT1066098B/it active
-
1978
- 1978-03-20 US US05/888,496 patent/US4490294A/en not_active Expired - Lifetime
-
1980
- 1980-05-07 US US06/147,584 patent/US4490295A/en not_active Expired - Lifetime
- 1980-05-07 US US06/147,614 patent/US4367175A/en not_active Expired - Lifetime
-
1989
- 1989-02-27 JP JP1046384A patent/JPH0222281A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
SE7601337L (sv) | 1976-11-03 |
JPH0222281A (ja) | 1990-01-25 |
US4367175A (en) | 1983-01-04 |
IE43790B1 (en) | 1981-06-03 |
DK49876A (US06420036-20020716-C00037.png) | 1976-08-08 |
SE421796B (sv) | 1982-02-01 |
FI63580C (fi) | 1983-07-11 |
FR2368276B1 (US06420036-20020716-C00037.png) | 1979-03-16 |
US4490295A (en) | 1984-12-25 |
US4490294A (en) | 1984-12-25 |
AT353409B (de) | 1979-11-12 |
DK141099B (da) | 1980-01-14 |
NL7601227A (nl) | 1976-08-10 |
DE2604697A1 (de) | 1976-08-19 |
IT1059403B (it) | 1982-05-31 |
IE43790L (en) | 1976-08-07 |
DK141099C (US06420036-20020716-C00037.png) | 1980-07-21 |
FR2368276A1 (fr) | 1978-05-19 |
AU1089176A (en) | 1977-08-11 |
IT1066098B (it) | 1985-03-04 |
ES444948A1 (es) | 1977-08-16 |
JPS51101994A (US06420036-20020716-C00037.png) | 1976-09-08 |
YU29076A (en) | 1982-08-31 |
AU509313B2 (en) | 1980-05-08 |
YU40452B (en) | 1986-02-28 |
FI760285A (US06420036-20020716-C00037.png) | 1976-08-08 |
ATA83476A (de) | 1979-04-15 |
FI63580B (fi) | 1983-03-31 |
DE2604697C2 (US06420036-20020716-C00037.png) | 1992-10-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE2552638C3 (de) | Thienamycin, Verfahren zu seiner Herstellung und Thienamycin enthaltende Arzneimittel | |
DE2560074C2 (de) | Verfahren zur Gewinnung von Clavulansäure und deren Salze | |
CH624956A5 (de) | Verfahren zur entfernung von verunreinigungen aus clavulansaeure. | |
DE2718782C2 (US06420036-20020716-C00037.png) | ||
DE2816608A1 (de) | Antibiotisches n-acetyl-dehydro- thienamycin | |
US4144242A (en) | Process for the purification of clavulanic acid | |
DE69628002T2 (de) | Herstellung von clavunalat-salzen | |
CH627494A5 (de) | Verfahren zur herstellung eines neuen antibioticums. | |
DE2340005A1 (de) | Beta-lactamaseinhibitoren und verfahren zu ihrer herstellung | |
JPS6366200B2 (US06420036-20020716-C00037.png) | ||
DE2652677C2 (de) | Antibiotica 890A↓1↓ und 890A↓3↓, Verfahren zu ihrer Herstellung und diese Antibiotika enthaltende antibakterielle Mittel | |
DE1952317A1 (de) | 3-Phosphat-Ester von Lincomycin,dessen Analysen und Celestin sowie Verfahren zu deren Herstellung | |
DE3782169T2 (de) | Verfahren zur herstellung von antibiotica 10381b. | |
DE1768965B1 (de) | (-)-(cis-1,2-Epoxypropyl)-phosphonsaeure und deren Salze und Verfahren zur Herstellung dieser Verbindungen | |
DE2652681C2 (de) | N-Acetylthienamycin, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Mittel | |
DE3132786C2 (de) | Antibiotikum SF-2103A, Verfahren zu dessen Herstellung und antibiotisches Mittel, welches das Antibiotikum enthält | |
DE2224640A1 (de) | Verbessertes Fermentationsverfahren | |
CH636127A5 (en) | Process for the preparation of the novel antibiotic MSD890A9 | |
AT364455B (de) | Verfahren zur herstellung von neuen phosphonsaeuren | |
KR800001241B1 (ko) | 클라블란산 항생물질의 정제방법 | |
AT366411B (de) | Verfahren zur herstellung einer neuen antibakte- riellen verbindung und deren salzen und estern | |
AT227384B (de) | Verfahren zur Herstellung eines neuen Antibiotikums und seiner Salze | |
DE2905066C2 (de) | Antibiotikum SF-2050B, Verfahren zur Herstellung desselben und antibakterielle Mittel, welche dasselbe enthalten | |
CH634104A5 (en) | Process for the preparation of the novel antibiotic MSD 890A10 | |
DE1153133B (de) | Verfahren zur Herstellung von 7-Chlor-6-desmethyltetracyclin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUE | Assignment |
Owner name: BEECHAM GROUP PLC |
|
PL | Patent ceased |