ES444948A1 - Un procedimiento para la separacion de impurezas contaminan-tes del acido clavulanico. - Google Patents

Un procedimiento para la separacion de impurezas contaminan-tes del acido clavulanico.

Info

Publication number
ES444948A1
ES444948A1 ES76444948A ES444948A ES444948A1 ES 444948 A1 ES444948 A1 ES 444948A1 ES 76444948 A ES76444948 A ES 76444948A ES 444948 A ES444948 A ES 444948A ES 444948 A1 ES444948 A1 ES 444948A1
Authority
ES
Spain
Prior art keywords
potassium salt
clavulanic acid
pure potassium
acid
pure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES76444948A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB540975A external-priority patent/GB1543563A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of ES444948A1 publication Critical patent/ES444948A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES76444948A 1975-02-07 1976-02-06 Un procedimiento para la separacion de impurezas contaminan-tes del acido clavulanico. Expired ES444948A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB540975A GB1543563A (en) 1975-02-07 1975-02-07 Beta-lactam antibiotic in purified form
GB1107675 1975-03-17

Publications (1)

Publication Number Publication Date
ES444948A1 true ES444948A1 (es) 1977-08-16

Family

ID=26239868

Family Applications (1)

Application Number Title Priority Date Filing Date
ES76444948A Expired ES444948A1 (es) 1975-02-07 1976-02-06 Un procedimiento para la separacion de impurezas contaminan-tes del acido clavulanico.

Country Status (15)

Country Link
US (3) US4490294A (es)
JP (2) JPS51101994A (es)
AT (1) AT353409B (es)
AU (1) AU509313B2 (es)
CH (1) CH624956A5 (es)
DE (1) DE2604697A1 (es)
DK (1) DK141099B (es)
ES (1) ES444948A1 (es)
FI (1) FI63580C (es)
FR (1) FR2368276A1 (es)
IE (1) IE43790B1 (es)
IT (2) IT1059403B (es)
NL (1) NL7601227A (es)
SE (1) SE421796B (es)
YU (1) YU40452B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
GB1542405A (en) * 1975-04-15 1979-03-21 Beecham Group Ltd Clavulanic acid derivatives
DE2862254D1 (en) * 1977-12-02 1983-06-16 Beecham Group Plc A process for the preparation of ether derivatives of clavulanic acid
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
GB9702216D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
ES2142641T3 (es) * 1997-03-24 2000-04-16 Cipan Comp Ind Prod Procedimiento para aislar una sal alcalino-metalica farmaceuticamente aceptable del acido clavulanico.
JPH11254368A (ja) * 1998-03-12 1999-09-21 Central Motor Co Ltd 部材保持装置
AU5409799A (en) * 1998-07-03 2000-01-24 Dsm N.V. Fermentation process to produce clavulanic acid at a low concentration of free amino acids
PT102181A (pt) * 1998-07-20 2000-01-31 Dsm Nv Processo melhorado para a producao de acido clavulanico
JP3737801B2 (ja) * 2000-10-05 2006-01-25 テバ ジョジセルジャール レースベニュタールシャシャーグ プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウム、並びにそれを含む組成物
US20040072815A1 (en) * 2002-02-12 2004-04-15 Koppel Gary A. Antibiotic composition and method
KR100461278B1 (ko) * 2002-10-23 2004-12-10 현대자동차주식회사 용접 대상물의 위치규제 및 취출장치
EP3692159A1 (en) 2017-10-02 2020-08-12 Metabolic Explorer Method for producing organic acid salts from fermentation broth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754693A (fr) * 1969-08-12 1971-02-11 Lilly Co Eli Nouvel antibiotique et procede pour le preparer
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration

Also Published As

Publication number Publication date
SE7601337L (sv) 1976-11-03
JPH0222281A (ja) 1990-01-25
US4367175A (en) 1983-01-04
IE43790B1 (en) 1981-06-03
DK49876A (es) 1976-08-08
SE421796B (sv) 1982-02-01
FI63580C (fi) 1983-07-11
FR2368276B1 (es) 1979-03-16
US4490295A (en) 1984-12-25
US4490294A (en) 1984-12-25
AT353409B (de) 1979-11-12
DK141099B (da) 1980-01-14
CH624956A5 (de) 1981-08-31
NL7601227A (nl) 1976-08-10
DE2604697A1 (de) 1976-08-19
IT1059403B (it) 1982-05-31
IE43790L (en) 1976-08-07
DK141099C (es) 1980-07-21
FR2368276A1 (fr) 1978-05-19
AU1089176A (en) 1977-08-11
IT1066098B (it) 1985-03-04
JPS51101994A (es) 1976-09-08
YU29076A (en) 1982-08-31
AU509313B2 (en) 1980-05-08
YU40452B (en) 1986-02-28
FI760285A (es) 1976-08-08
ATA83476A (de) 1979-04-15
FI63580B (fi) 1983-03-31
DE2604697C2 (es) 1992-10-29

Similar Documents

Publication Publication Date Title
ES469568A1 (es) Procedimiento para la obtencion de compuestos de acido 2-pe-nem-3-carboxilicos
IE45256L (en) Quinazolone derivatives
ES444948A1 (es) Un procedimiento para la separacion de impurezas contaminan-tes del acido clavulanico.
GB1418822A (en) Imidazo-and pyrimido-2,1-b-quinazolin-2-ones and a process for the preparation thereof
ES463974A1 (es) Un procedimiento para la preparacion de nuevos derivados delacido clavulanico.
ES8303423A1 (es) Un procedimiento para preparar compuestos de cefem
ES453161A1 (es) Un procedimiento de preparacion de espiro (1,3-dioxolan-4,3)quinuclidinas.
DE3267188D1 (en) Hydroxybenzylamino-aryl compounds, process for preparing and pharmaceutical compositions containing the same
ES8308833A1 (es) "un metodo para la preparacion de 3-fenil-1-indanaminas".
ES8407009A1 (es) Un procedimiento para preparar -15-desoxiespergualina.
ES8104222A1 (es) Un procedimiento para la preparacion de derivados del acido 7-oxo-1-aza-biciclo (3,2,0) hept-2-en-2-carboxilico
JPS5271456A (en) Synthesis of 1alpha-hydroxysteroid derivatives
ES481271A1 (es) Procedimiento de preparacion de derivados de la l-cisteina.
ES8201531A1 (es) Procedimiento de preparar alcoxi propanolaminas
ES482194A1 (es) Procedimiento para la obtencion de compuestos de acido 7- aminotiazolilacetamido-3-cefem-4-carboxilico.
IE43872L (en) 2,9-dioxatricyclo [4.3.1.0(3,7)] decanes
IE34590B1 (en) Phenylethanolamine derivatives
IL51065A (en) Pharmaceutical compositions containing triphenylmethanedi-carboxylic acid derivatives and analogs thereof,some novel compounds of this type and process for their preparation
GB1428933A (en) 5-phenyl-sulphinyl-2-benzimidazolyl-carbamic acid esters and process for their manufacture
ES8105316A1 (es) Procedimiento para preparar la sal de d-diamonio del anti- biotico de oxa-beta-lactama
ES8302093A1 (es) Un procedimiento para obtener nuevos compuestos de beta-lac-tama
JPS51115402A (en) Process for preparation of alpha-amino acid
JPS5223037A (en) Process for preparation of optical active amino acid
JPS5331683A (en) Novel process for preparation of alpha-amino acid derivatives
JPS52136165A (en) Purification of pyrrolidine derivatives