AU5409799A - Fermentation process to produce clavulanic acid at a low concentration of free amino acids - Google Patents

Fermentation process to produce clavulanic acid at a low concentration of free amino acids

Info

Publication number
AU5409799A
AU5409799A AU54097/99A AU5409799A AU5409799A AU 5409799 A AU5409799 A AU 5409799A AU 54097/99 A AU54097/99 A AU 54097/99A AU 5409799 A AU5409799 A AU 5409799A AU 5409799 A AU5409799 A AU 5409799A
Authority
AU
Australia
Prior art keywords
amino acids
low concentration
fermentation process
free amino
clavulanic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU54097/99A
Inventor
Wilhelmus Theodorus Antonius Maria De Laat
Preben Krabben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Publication of AU5409799A publication Critical patent/AU5409799A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU54097/99A 1998-07-03 1999-07-01 Fermentation process to produce clavulanic acid at a low concentration of free amino acids Abandoned AU5409799A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98202264 1998-07-03
EP98202264 1998-07-03
PCT/EP1999/004702 WO2000001840A1 (en) 1998-07-03 1999-07-01 Fermentation process to produce clavulanic acid at a low concentration of free amino acids

Publications (1)

Publication Number Publication Date
AU5409799A true AU5409799A (en) 2000-01-24

Family

ID=8233894

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54097/99A Abandoned AU5409799A (en) 1998-07-03 1999-07-01 Fermentation process to produce clavulanic acid at a low concentration of free amino acids

Country Status (7)

Country Link
EP (1) EP1097238A1 (en)
CN (1) CN1308682A (en)
AU (1) AU5409799A (en)
CA (1) CA2336363A1 (en)
MX (1) MXPA00012930A (en)
TR (1) TR200003828T2 (en)
WO (1) WO2000001840A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122305A1 (en) * 2000-01-31 2001-08-08 Dsm N.V. Glutamate dehydrogenase-transformed streptomyces clavuligerus with an improved capacity to assimilate ammonia
WO2009138994A1 (en) * 2008-05-14 2009-11-19 Biocon Limited A fermentation process for the production of secondary metabolites
KR101723167B1 (en) * 2015-04-28 2017-04-05 주식회사 대웅 Medium Composition for Preparing Botulinum Toxin
KR101729251B1 (en) 2015-04-28 2017-04-21 주식회사 대웅 Medium Composition for Preparing Botulinum Toxin
CN105817190B (en) * 2016-03-15 2019-01-08 浙江凯色丽科技发展有限公司 Hydrolyze automatic control system
CN111944734B (en) * 2019-05-17 2023-01-10 中国科学院微生物研究所 Method for improving yield of streptomycete polyketide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
IT1059403B (en) * 1975-02-07 1982-05-31 Glaxo Lab Ltd PROCEDURE FOR PRODUCING CLAVULANIC ACID AND ITS DERIVATIVES AS WELL AS COMPOSITIONS CONTAINING IT
EP0026044B1 (en) * 1979-08-24 1983-06-08 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use

Also Published As

Publication number Publication date
CA2336363A1 (en) 2000-01-13
CN1308682A (en) 2001-08-15
WO2000001840A1 (en) 2000-01-13
EP1097238A1 (en) 2001-05-09
MXPA00012930A (en) 2002-05-08
TR200003828T2 (en) 2001-06-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase